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لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Yang ZQ; Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486, USA. zhiqiang_yang@merck.com, Barrow JC, Shipe WD, Schlegel KA, Shu Y, Yang FV, Lindsley CW, Rittle KE, Bock MG, Hartman GD, Uebele VN, Nuss CE, Fox SV, Kraus RL, Doran SM, Connolly TM, Tang C, Ballard JE, Kuo Y, Adarayan ED, Prueksaritanont T, Zrada MM, Marino MJ, Graufelds VK, DiLella AG, Reynolds IJ, Vargas HM, Bunting PB, Woltmann RF, Magee MM, Koblan KS, Renger JJ

المصدر: Journal of medicinal chemistry [J Med Chem] 2008 Oct 23; Vol. 51 (20), pp. 6471-7. Date of Electronic Publication: 2008 Sep 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Calcium Channel Blockers/*chemical synthesis , Calcium Channel Blockers/*pharmacology , Calcium Channels, T-Type/*metabolism , Piperidines/*chemical synthesis , Piperidines/*pharmacology, Animals ; Calcium Channel Blockers/chemistry ; Cardiovascular System/drug effects ; Drug Evaluation, Preclinical ; Humans ; Molecular Structure ; Piperidines/chemistry ; Rats ; Structure-Activity Relationship

المؤلفون: Forrest MJ; Cardiovascular Diseases, Merck Research Laboratories, Rahway, NJ 07065, USA. mike_forrest@merck.com, Bloomfield D, Briscoe RJ, Brown PN, Cumiskey AM, Ehrhart J, Hershey JC, Keller WJ, Ma X, McPherson HE, Messina E, Peterson LB, Sharif-Rodriguez W, Siegl PK, Sinclair PJ, Sparrow CP, Stevenson AS, Sun SY, Tsai C, Vargas H, Walker M 3rd, West SH, White V, Woltmann RF

المصدر: British journal of pharmacology [Br J Pharmacol] 2008 Aug; Vol. 154 (7), pp. 1465-73. Date of Electronic Publication: 2008 Jun 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0007-1188 (Print) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Blood Pressure/*drug effects , Cholesterol Ester Transfer Proteins/*antagonists & inhibitors , Oxazolidinones/*toxicity , Quinolines/*toxicity, Adrenal Cortex/cytology ; Adrenal Cortex/drug effects ; Aldosterone/blood ; Animals ; Anticholesteremic Agents/toxicity ; Corticosterone/blood ; Dogs ; Drug Evaluation, Preclinical ; Female ; Macaca mulatta ; Male ; Mice ; Mice, Inbred C57BL ; Models, Animal ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Rats ; Rats, Sprague-Dawley ; Species Specificity

المؤلفون: Tucker TJ; Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486, USA., Lumma WC, Lewis SD, Gardell SJ, Lucas BJ, Sisko JT, Lynch JJ, Lyle EA, Baskin EP, Woltmann RF, Appleby SD, Chen IW, Dancheck KB, Naylor-Olsen AM, Krueger JA, Cooper CM, Vacca JP

المصدر: Journal of medicinal chemistry [J Med Chem] 1997 Oct 24; Vol. 40 (22), pp. 3687-93.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Propionates/*chemical synthesis , Thrombin/*antagonists & inhibitors, Administration, Oral ; Animals ; Biological Availability ; Dogs ; Magnetic Resonance Spectroscopy ; Propionates/pharmacokinetics ; Propionates/pharmacology ; Rats ; Spectrometry, Mass, Fast Atom Bombardment

المؤلفون: Barrett JA; RW Johnson Pharmaceutical Research Institute Welsh and McKean Roads Spring House PA 19477 USA., Derian CK, Swillo RS, Woltmann RF, Perrone MH

المصدر: Mediators of inflammation [Mediators Inflamm] 1993; Vol. 2 (1), pp. 85-92.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 9209001 Publication Model: Print Cited Medium: Print ISSN: 0962-9351 (Print) Linking ISSN: 09629351 NLM ISO Abbreviation: Mediators Inflamm Subsets: PubMed not MEDLINE