المؤلفون: Rodrigueza WV; ProNAi Therapeutics, Inc., Plymouth, MI, USA, wrodrigueza@pronai.com., Woolliscroft MJ, Ebrahim AS, Forgey R, McGovren PJ, Endert G, Wagner A, Holewa D, Aboukameel A, Gill RD, Bisgaier CL, Messmann RA, Whitehead CE, Izbicka E, Streeper R, Wick MC, Stiegler G, Stein CA, Monsma D, Webb C, Sooch MP, Panzner S, Mohammad R, Goodwin NC, Al-Katib A

المصدر: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2014 Jul; Vol. 74 (1), pp. 151-66. Date of Electronic Publication: 2014 May 16.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , DNA, Antisense/*therapeutic use , DNA, Single-Stranded/*therapeutic use , Gene Silencing/*drug effects , Neoplasms/*drug therapy , Proto-Oncogene Proteins c-bcl-2/*antagonists & inhibitors, 5' Flanking Region/drug effects ; Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/metabolism ; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cell Line, Tumor ; Cell Survival/drug effects ; DNA, Antisense/administration & dosage ; DNA, Antisense/pharmacokinetics ; DNA, Antisense/pharmacology ; DNA, Single-Stranded/administration & dosage ; DNA, Single-Stranded/pharmacokinetics ; DNA, Single-Stranded/pharmacology ; Drug Compounding ; Drug Stability ; Female ; Liposomes ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Mice, SCID ; Neoplasms/blood ; Oligodeoxyribonucleotides/chemistry ; Oligodeoxyribonucleotides/pharmacokinetics ; Oligodeoxyribonucleotides/pharmacology ; Oligodeoxyribonucleotides/therapeutic use ; Pharmaceutical Vehicles ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Random Allocation ; Xenograft Model Antitumor Assays

المؤلفون: Tolcher AW; South Texas Accelerated Research Therapeutics (START), LLC, San Antonio, TX, USA., Rodrigueza WV, Rasco DW, Patnaik A, Papadopoulos KP, Amaya A, Moore TD, Gaylor SK, Bisgaier CL, Sooch MP, Woolliscroft MJ, Messmann RA

المصدر: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2014 Feb; Vol. 73 (2), pp. 363-71. Date of Electronic Publication: 2013 Dec 03.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms/*drug therapy , Oligodeoxyribonucleotides/*administration & dosage , Oligonucleotides/*administration & dosage , Proto-Oncogene Proteins c-bcl-2/*genetics, Adult ; Aged ; Aged, 80 and over ; DNA/antagonists & inhibitors ; Female ; Humans ; Liposomes/administration & dosage ; Male ; Maximum Tolerated Dose ; Middle Aged ; Molecular Targeted Therapy ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Oligonucleotides/adverse effects ; Oligonucleotides/pharmacokinetics ; Treatment Outcome

المؤلفون: McConville P; MIR Preclinical Services, Inc., Ann Arbor, Michigan, USA., Hambardzumyan D, Moody JB, Leopold WR, Kreger AR, Woolliscroft MJ, Rehemtulla A, Ross BD, Holland EC

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2007 May 15; Vol. 13 (10), pp. 2897-904.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Print ISSN: 1078-0432 (Print) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Magnetic Resonance Imaging*, Brain Neoplasms/*drug therapy , Brain Neoplasms/*pathology , Dacarbazine/*analogs & derivatives , Glioma/*drug therapy , Glioma/*pathology, Animals ; Brain Neoplasms/mortality ; Dacarbazine/therapeutic use ; Disease Models, Animal ; Genetic Engineering ; Glioma/mortality ; Mice ; Mice, Mutant Strains ; Neoplasm Invasiveness ; Neoplasm Staging ; Prognosis ; Retroviridae/genetics ; Temozolomide

المؤلفون: Reddy GR; Molecular Therapeutics, Inc., Ann Arbor, MI 48109, USA., Bhojani MS, McConville P, Moody J, Moffat BA, Hall DE, Kim G, Koo YE, Woolliscroft MJ, Sugai JV, Johnson TD, Philbert MA, Kopelman R, Rehemtulla A, Ross BD

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2006 Nov 15; Vol. 12 (22), pp. 6677-86.

نوع المنشور: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Print ISSN: 1078-0432 (Print) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Brain Neoplasms/*diagnostic imaging , Brain Neoplasms/*therapy , Glioma/*diagnostic imaging , Glioma/*therapy , Nanoparticles/*therapeutic use , Photochemotherapy/*methods, Angiography/methods ; Animals ; Blood Vessels/drug effects ; Brain Neoplasms/blood supply ; Brain Neoplasms/mortality ; Diagnostic Imaging/methods ; Dihematoporphyrin Ether/administration & dosage ; Drug Administration Routes ; Drug Carriers/therapeutic use ; Ferric Compounds/administration & dosage ; Glioma/blood supply ; Glioma/mortality ; Humans ; Male ; Nanotechnology ; Photosensitizing Agents/administration & dosage ; Rats ; Survival Analysis ; Tumor Cells, Cultured