المؤلفون: Megan Garland, Christopher J Schulze, Ian T Foe, Wouter A van der Linden, Matthew A Child, Matthew Bogyo

المصدر: PLoS ONE, Vol 13, Iss 1, p e0190255 (2018)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5783350?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e5d8492e87b545fe8500288befcbf7ae

المؤلفون: Christine S Hopp, Brandy L Bennett, Satish Mishra, Christine Lehmann, Kirsten K Hanson, Jing-Wen Lin, Kimberly Rousseau, Filomena A Carvalho, Wouter A van der Linden, Nuno C Santos, Matthew Bogyo, Shahid M Khan, Volker Heussler, Photini Sinnis

المصدر: PLoS Pathogens, Vol 13, Iss 9, p e1006586 (2017)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/89689e3f69b94011b1a32244742d0945

المؤلفون: Laura E Sanman, Yu Qian, Nicholas A Eisele, Tessie M Ng, Wouter A van der Linden, Denise M Monack, Eranthie Weerapana, Matthew Bogyo

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: Salmonella typhimurium, inflammasome, glycolysis, pyroptosis, NLRP3, Caspase-1, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/13663; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/ee523f6403ad4773923afdc7233086a7

المؤلفون: Marianne Kraus, Juergen Bader, Paul P. Geurink, Emily S. Weyburne, Anne C. Mirabella, Tobias Silzle, Tamer B. Shabaneh, Wouter A. van der Linden, Gerjan de Bruin, Sarah R. Haile, Eva van Rooden, Christina Appenzeller, Nan Li, Alexei F. Kisselev, Herman Overkleeft, Christoph Driessen

المصدر: Haematologica, Vol 100, Iss 10 (2015)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://haematologica.org/article/view/7530; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

URL الوصول: https://doaj.org/article/aedeca40c19b4a6f8ec5f90a0475552f

المؤلفون: Paula C. A. da Fonseca, Leann Tilley, Wouter A. van der Linden, Ian T. Foe, Matthew Bogyo, Hao Li, Euna Yoo, Charles S. Craik, Anthony J. O’Donoghue, Stanley C. Xie

المصدر: Nature

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Plasmodium, Proteasome Endopeptidase Complex, Proteases, medicine.medical_treatment, Plasmodium falciparum, Antigen presentation, Drug Resistance, 01 natural sciences, Article, Substrate Specificity, Plasmodium chabaudi, Antimalarials, Mice, 03 medical and health sciences, Enzyme activator, Species Specificity, Catalytic Domain, parasitic diseases, medicine, Animals, Humans, Mice, Inbred BALB C, Multidisciplinary, Protease, Dose-Response Relationship, Drug, biology, 010405 organic chemistry, Cryoelectron Microscopy, Drug Synergism, Cell cycle, biology.organism_classification, Artemisinins, 0104 chemical sciences, 3. Good health, Cell biology, Enzyme Activation, Protein Subunits, 030104 developmental biology, Proteasome, Biochemistry, Drug Design, Female, Proteasome Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746e8cfba41d92ca1128b6968f29f854
https://doi.org/10.1038/nature16936

المؤلفون: Hao Li, Anthony J. O'Donoghue, Wouter A. van der Linden, Stanley C. Xie, Euna Yoo, Ian T. Foe, Leann Tilley, Charles S. Craik, Paula C. A. da Fonseca, Matthew Bogyo

المصدر: Nature, Nature. 530(7589):233-236

الإتاحة: https://ideas.repec.org/a/nat/nature/v530y2016i7589d10.1038_nature16936.html

المؤلفون: Wouter A. van der Linden, Jing-wen Lin, Shahid M. Khan, Kimberly E Rousseau, Kirsten K. Hanson, Christine S. Hopp, Photini Sinnis, Satish Mishra, Christine Lehmann, Brandy L. Bennett, Matthew Bogyo, Volker Heussler, Filomena A. Carvalho, Nuno C. Santos

المساهمون: Repositório da Universidade de Lisboa

المصدر: PLoS Pathogens, Vol 13, Iss 9, p e1006586 (2017)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Pathogens, 13(9)
Hopp, Christine S; Bennett, Brandy L; Mishra, Satish; Lehmann, Christine; Hanson, Kirsten K; Lin, Jing-Wen; Rousseau, Kimberly; Carvalho, Filomena A; van der Linden, Wouter A; Santos, Nuno C; Bogyo, Matthew; Khan, Shahid M; Heussler, Volker; Sinnis, Photini (2017). Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites. PLoS pathogens, 13(9), e1006586. Public Library of Science 10.1371/journal.ppat.1006586 <http://dx.doi.org/10.1371/journal.ppat.1006586>
PLoS Pathogens

مصطلحات موضوعية: 0301 basic medicine, Erythrocytes, Physiology, Quantitative Parasitology, medicine.medical_treatment, Protozoan Proteins, Parasitemia, Plasmodium, Animal Cells, Red Blood Cells, Medicine and Health Sciences, Parasite hosting, Biology (General), 610 Medicine & health, Infectivity, Protozoans, biology, Malarial Parasites, Eukaryota, Cysteine protease, Cell biology, Body Fluids, Cysteine Endopeptidases, Blood, Liver, Sporozoites, Anatomy, Cellular Types, Research Article, Proteases, QH301-705.5, Immunology, Plasmodium falciparum, Cysteine Proteinase Inhibitors, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Virology, Parasite Groups, Genetics, medicine, Parasitic Diseases, Animals, Molecular Biology Techniques, Molecular Biology, Protease, Blood Cells, Merozoites, Organisms, Biology and Life Sciences, Cell Biology, RC581-607, biology.organism_classification, medicine.disease, Parasitic Protozoans, Malaria, 030104 developmental biology, Hepatocytes, 570 Life sciences, Parasitology, Immunologic diseases. Allergy, Apicomplexa, Cloning

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e645e652c422ca7fcc4afeb28712e0
https://doaj.org/article/89689e3f69b94011b1a32244742d0945

المؤلفون: Emily S. Weyburne, Christina Appenzeller, Gerjan de Bruin, Wouter A. van der Linden, Tobias Silzle, Paul P. Geurink, Sarah R. Haile, Herman S. Overkleeft, Eva van Rooden, Nan Li, Alexei F. Kisselev, Juergen Bader, Anne C. Mirabella, Marianne Kraus, Christoph Driessen, Tamer B. Shabaneh

المصدر: Haematologica
Haematologica, 100(10), 1350-1360

مصطلحات موضوعية: Antineoplastic Agents, Pharmacology, Bortezomib, chemistry.chemical_compound, Mice, immune system diseases, Cell Line, Tumor, hemic and lymphatic diseases, medicine, Animals, Humans, Multiple myeloma, Chemistry, Drug Synergism, Hematology, Articles, medicine.disease, Carfilzomib, Xenograft Model Antitumor Assays, 3. Good health, Disease Models, Animal, Proteasome, Apoptosis, Drug Resistance, Neoplasm, Cancer cell, Proteasome inhibitor, Unfolded protein response, Multiple Myeloma, Oligopeptides, Proteasome Inhibitors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53fc42d6e4b0b05336c92e9304d8e95
http://www.haematologica.org/content/100/10/1350.long

المؤلفون: Manlio Di Cristina, Tracey L. Schultz, Isabelle Coppens, Wouter A. van der Linden, Sébastien Besteiro, Zhicheng Dou, Alyssa J. Miller, Matthew Bogyo, Matteo Lunghi, Geetha Kannan, Vern B. Carruthers, Beth M. Hayes, Aric J. Schultz, Carla Emiliani, Olivia L. McGovern, My Hang Huynh

المصدر: Nature Microbiology. 2

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Protease, medicine.diagnostic_test, medicine.medical_treatment, Proteolysis, Immunology, Autophagy, Cell Biology, Biology, Applied Microbiology and Biotechnology, Microbiology, Virology, Cysteine protease, 3. Good health, 03 medical and health sciences, Chronic infection, 030104 developmental biology, Organelle, Genetics, medicine, Parasite hosting, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6282191f28f1a6cfcb0c15ac6bf0be
https://doi.org/10.1038/nmicrobiol.2017.96

المؤلفون: Peter Madzelan, Kristina Oresic Bender, Wouter A. van der Linden, Michael L. Reese, Moritz Treeck, Mark A. Wilson, Eranthie Weerapana, John C. Boothroyd, Ian T. Foe, Matthew Bogyo, Megan Garland, Matthew A. Child

المصدر: mBio
mBio, Vol 8, Iss 1 (2017)
mBio, Vol 8, Iss 1, p e02189-16 (2017)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, REPLACEMENTS, Protein Conformation, INVASION, Protein Deglycase DJ-1, INHIBITION, Crystallography, X-Ray, Exosomes, Microbiology, Exocytosis, Microneme, 03 medical and health sciences, PARKINSONS-DISEASE, Virology, Organelle, CRYSTAL-STRUCTURE, Secretion, Kinase activity, Protein kinase A, Science & Technology, MUTAGENESIS, Effector, Chemistry, Kinase, Intracellular parasite, SUPERFAMILY, PROTOZOAN PARASITE, QR1-502, 3. Good health, Cell biology, 030104 developmental biology, Calcium, GONDII, HOST-CELLS, Life Sciences & Biomedicine, Oxidation-Reduction, Protein Kinases, Toxoplasma, 0605 Microbiology, Research Article, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629625b1233b30c2c233b697f70aebb1
http://europepmc.org/articles/PMC5347346