نتائج البحث - "Wouter F. Tonnis"

1

دورية أكاديمية

Pulmonary immunization: deposition site is of minor relevance for influenza vaccination but deep lung deposition is crucial for hepatitis B vaccination

المؤلفون: Jasmine Tomar, Wouter F. Tonnis, Harshad P. Patil, Anne H. de boer, Paul Hagedoorn, Rita Vanbever, Henderik W. Frijlink, Wouter L.J. Hinrichs

المصدر: Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1231-1240 (2019)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383519300991; https://doaj.org/toc/2211-3835

URL الوصول: https://doaj.org/article/e79481a79611462b9c54db7a3e21991f

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دورية أكاديمية

Association of plasma somatostatin with disease severity and progression in patients with autosomal dominant polycystic kidney disease

المؤلفون: A. Lianne Messchendorp, Edwin M. Spithoven, Niek F. Casteleijn, Wendy A. Dam, Jacob van den Born, Wouter F. Tonnis, Carlo A. J. M. Gaillard, Esther Meijer, on behalf of the DIPAK Consortium

المصدر: BMC Nephrology, Vol 19, Iss 1, Pp 1-10 (2018)

مصطلحات موضوعية: ADPKD, Somatostatin, Biomarker, cAMP, Disease progression, Diseases of the genitourinary system. Urology, RC870-923

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12882-018-1176-y; https://doaj.org/toc/1471-2369

URL الوصول: https://doaj.org/article/5ffdb32fedf24b4aa7465562d43628c9

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3

Pulmonary immunization

المؤلفون: Rita Vanbever, Anne H. de Boer, Harshad P. Patil, Henderik W. Frijlink, Wouter L. J. Hinrichs, Paul Hagedoorn, Wouter F. Tonnis, Jasmine Tomar

المساهمون: Pharmaceutical Technology and Biopharmacy, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanotechnology and Biophysics in Medicine (NANOBIOMED), UCL - SSS/LDRI - Louvain Drug Research Institute

المصدر: Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1231-1240 (2019)
Acta Pharmaceutica Sinica B, 9(6), 1231-1240. Chinese Academy of Medical Sciences
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, (2019)

مصطلحات موضوعية: Deep lung deposition, aerosol, trachea, immunogenicity, powder, Toxicology and Pharmaceutics, immune response, 0302 clinical medicine, Medicine, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, Immunogenicity, article, Hepatitis B, respiratory system, influenza vaccination, 3. Good health, Vaccination, medicine.anatomical_structure, Inhalation, 030220 oncology & carcinogenesis, subunit vaccine, Powders, Original article, Hepatitis B vaccine, Influenza vaccine, aerosol generator, animal experiment, lung, 03 medical and health sciences, Antigen, General Pharmacology, controlled study, mouse, 030304 developmental biology, Lung, nonhuman, business.industry, lcsh:RM1-950, medicine.disease, Influenza, drug formulation, hepatitis B surface antigen, lcsh:Therapeutics. Pharmacology, Immunization, airway, Immunology, fluorescent dye, influenza vaccine, business, hepatitis B vaccine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5a794613c7a9d4d4089e321c0084da
https://hdl.handle.net/11370/5da93227-90e1-4a77-b15a-73f30f1cb5f3

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Efficient production of solid dispersions by spray drying solutions of high solid content using a 3-fluid nozzle

المؤلفون: Joep Broekhuis, Niels Grasmeijer, Henderik W. Frijlink, Wouter L. J. Hinrichs, Jarkko Ketolainen, Ari Kauppinen, Wouter F. Tonnis

المساهمون: School of Pharmacy, Activities, Pharmaceutical Technology and Biopharmacy, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanotechnology and Biophysics in Medicine (NANOBIOMED)

المصدر: European Journal of Pharmaceutics and Biopharmaceutics, 123, 50-58. ELSEVIER SCIENCE BV

مصطلحات موضوعية: Dissolution rate, Yield, Materials science, Solid dispersion, BIOAVAILABILITY, Drug Compounding, Ethyl acetate, Pharmaceutical Science, 02 engineering and technology, SOLUBILITY, 030226 pharmacology & pharmacy, Lipophilic drug, Spray nozzle, Poor water solubility, 03 medical and health sciences, chemistry.chemical_compound, Crystallinity, 3-Fluid nozzle, 0302 clinical medicine, DISSOLUTION, DRUGS, WATER, Mannitol, Particle Size, Solubility, MICROENCAPSULATION, FORMULATION, Dissolution, Drug Carriers, Diazepam, Chromatography, MICROPARTICLES, Spray drying, General Medicine, 021001 nanoscience & nanotechnology, Solutions, Solvent, chemistry, Chemical engineering, Solvents, Particle size, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions, Design of experiments, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8414ca477f7b6ab1bc7683df11fca736
https://doi.org/10.1016/j.ejpb.2017.11.009

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Development and potential application of an oral ColoPulse infliximab tablet with colon specific release: A feasibility study

المؤلفون: Herman J. Woerdenbag, Jos G. W. Kosterink, J.M. Maurer, R.C.A. Schellekens, Henderik W. Frijlink, Wouter L. J. Hinrichs, Susan Hofman, Wouter F. Tonnis, Annelien O. T. Dubois

المساهمون: Pharmaceutical Technology and Biopharmacy, Pharmaceutical Technology and Biopharmacy (GRIP), Nanotechnology and Biophysics in Medicine (NANOBIOMED), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Targeted Gynaecologic Oncology (TARGON), PharmacoTherapy, -Epidemiology and -Economics

المصدر: International Journal of Pharmaceutics, 505(1-2), 175-186. Elsevier Bedrijfsinformatie b.v.

مصطلحات موضوعية: STABILIZATION, Time Factors, BIOAVAILABILITY, Chemistry, Pharmaceutical, medicine.medical_treatment, Pharmaceutical Science, ColoPulse, 02 engineering and technology, Pharmacology, Colon specific, Colon specific delivery, Drug Delivery Systems, 0302 clinical medicine, Crohn Disease, Drug Stability, Protein stability, skin and connective tissue diseases, Gastrointestinal agent, 021001 nanoscience & nanotechnology, CROHNS-DISEASE, Crohn's disease, Oral delivery, GLASSES, INULIN, LOCAL INJECTION, 030211 gastroenterology & hepatology, 0210 nano-technology, Local injection, BEHAVIOR, Tablets, medicine.drug, musculoskeletal diseases, Colon, PROTEINS, medicine.drug_class, Drug Storage, Monoclonal antibody, Excipients, 03 medical and health sciences, Gastrointestinal Agents, medicine, STABILITY, Crohn disease, business.industry, Infliximab, Formulation, Intravenous therapy, Delayed-Action Preparations, ANTIBODIES, Feasibility Studies, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77f27eda4ef6de4483d5a64c6a617ab
https://doi.org/10.1016/j.ijpharm.2016.03.027

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Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge

المؤلفون: Harshad P. Patil, Rita Vanbever, Nikolai Petrovsky, Gustavo Bracho, Wouter F. Tonnis, Jasmine Tomar, Henderik W. Frijlink, Wouter L. J. Hinrichs, Anke Huckriede

المساهمون: UCL - SSS/LDRI - Louvain Drug Research Institute, Pharmaceutical Technology and Biopharmacy, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Translational Immunology Groningen (TRIGR), Nanotechnology and Biophysics in Medicine (NANOBIOMED)

المصدر: Journal of controlled release : official journal of the Controlled Release Society, Vol. 288, p. 199-211 (2018)
Journal of Controlled Release, 288, 199-211. Elsevier Bedrijfsinformatie b.v.
Journal of Controlled Release

مصطلحات موضوعية: 0301 basic medicine, T-Lymphocytes, Pharmaceutical Science, Immune mechanisms, Antibodies, Viral, IMMUNOGENICITY, 0302 clinical medicine, Influenza A Virus, H1N1 Subtype, Medicine, 030212 general & internal medicine, B-Lymphocytes, Mice, Inbred BALB C, Mucosal, DELTA INULIN ADJUVANT, Protection, IMMUNE-RESPONSES, Immunogenicity, Inulin, Whole inactivated influenza vaccine, 3. Good health, Vaccination, Inhalation, Influenza Vaccines, Female, Powders, Influenza vaccine, Respiratory Mucosa, Article, Advax, 03 medical and health sciences, DELIVERY, Immune system, Adjuvants, Immunologic, Orthomyxoviridae Infections, Immunity, PULMONARY IMMUNIZATION, VACCINES, Administration, Inhalation, Animals, business.industry, Lethal dose, MEMORY, 030104 developmental biology, Immunization, Vaccines, Inactivated, Immunology, ANTIBODIES, Nasal administration, POLYSACCHARIDE ADJUVANT, business, GENERATION

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5282395ec36b28905755870186f89b9b
https://hdl.handle.net/2078.1/203430

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Size and Molecular Flexibility of Sugars Determine the Storage Stability of Freeze-Dried Proteins

المؤلفون: Maarten A Mensink, Wouter F. Tonnis, A.E.J. de Jager, K. van der Voort Maarschalk, Henderik W. Frijlink, Wouter L. J. Hinrichs

المساهمون: Pharmaceutical Technology and Biopharmacy, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanotechnology and Biophysics in Medicine (NANOBIOMED)

المصدر: Molecular pharmaceutics, 12(3), 684-694. AMER CHEMICAL SOC INC

مصطلحات موضوعية: DYNAMICS, STABILIZATION, PHARMACEUTICALS, GLASS-TRANSITION, Chemistry, Pharmaceutical, Drug Storage, TREHALOSE, lyophilization, Carbohydrates, Disaccharide, Pharmaceutical Science, Polysaccharide, DEXTRAN, MECHANISMS, Biopharmaceutics, chemistry.chemical_compound, Drug Stability, oligosaccharides, Drug Discovery, PARTICLES, Humans, Transition Temperature, Sugar, chemistry.chemical_classification, SPECTROSCOPY, Chromatography, Aqueous solution, inulin, Molecular Structure, Protein Stability, Hydrogen bond, Proteins, Oligosaccharide, Trehalose, mobility, vitrification, Molecular Weight, SOLID-STATE, Freeze Drying, Spectrometry, Fluorescence, Dextran, chemistry, water replacement, steric hindrance, Molecular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec969ca7d5a948de9894e70ba638d24
https://doi.org/10.1021/mp500423z

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A novel aerosol generator for homogenous distribution of powder over the lungs after pulmonary administration to small laboratory animals

المؤلفون: Jelmer Sjollema, Wouter F. Tonnis, Marieke Bagerman, Henderik W. Frijlink, Wouter L. J. Hinrichs, Michel Weij, Anne H. de Boer

المساهمون: Pharmaceutical Technology and Biopharmacy, Man, Biomaterials and Microbes (MBM), Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanotechnology and Biophysics in Medicine (NANOBIOMED)

المصدر: European Journal of Pharmaceutics and Biopharmaceutics, 88(3), 1056-1063. ELSEVIER SCIENCE BV