المؤلفون: Currie SP; Muir Maxwell Epilepsy Centre, Patrick Wild Centre, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom., Luz LL; Muir Maxwell Epilepsy Centre, Patrick Wild Centre, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom., Booker SA; Muir Maxwell Epilepsy Centre, Patrick Wild Centre, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom., Wyllie DJ; Muir Maxwell Epilepsy Centre, Patrick Wild Centre, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, InStem, Bangalore, India., Kind PC; Muir Maxwell Epilepsy Centre, Patrick Wild Centre, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, InStem, Bangalore, India., Daw MI; Muir Maxwell Epilepsy Centre, Patrick Wild Centre, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.

المصدر: Epilepsia [Epilepsia] 2017 Apr; Vol. 58 (4), pp. 597-607. Date of Electronic Publication: 2017 Feb 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE

مواضيع طبية MeSH: Epilepsy, Absence/*genetics , Epilepsy, Absence/*pathology , Interneurons/*physiology , Point Mutation/*genetics , Receptors, GABA-A/*genetics , Somatosensory Cortex/*pathology, Action Potentials/drug effects ; Action Potentials/genetics ; Analysis of Variance ; Animals ; Animals, Newborn ; Arginine/genetics ; Disease Models, Animal ; Female ; Glutamic Acid/genetics ; In Vitro Techniques ; Inhibitory Postsynaptic Potentials/drug effects ; Inhibitory Postsynaptic Potentials/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Patch-Clamp Techniques

المؤلفون: Booker SA; Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK.; Patrick Wild Centre, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK., Campbell GR; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Mysiak KS; Centre for Neuroregeneration, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Brophy PJ; Centre for Neuroregeneration, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Kind PC; Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK.; Patrick Wild Centre, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, 560065, India., Mahad DJ; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Wyllie DJ; Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK.; Patrick Wild Centre, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, 560065, India.

المصدر: The Journal of physiology [J Physiol] 2017 Mar 15; Vol. 595 (6), pp. 2147-2160.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Alkyl and Aryl Transferases/*physiology , CA3 Region, Hippocampal/*physiology , Dentate Gyrus/*physiology , Membrane Proteins/*physiology , Mossy Fibers, Hippocampal/*physiology , Pyramidal Cells/*physiology, Alkyl and Aryl Transferases/genetics ; Animals ; Membrane Proteins/genetics ; Mice, Transgenic ; Synaptic Transmission

المؤلفون: Zanato C; Kosterlitz Centre for Therapeutics, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, Scotland, UK. m.zanda@abdn.ac.uk., Pelagalli A; Kosterlitz Centre for Therapeutics, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, Scotland, UK. m.zanda@abdn.ac.uk., Marwick KF; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, EH8 9XD, Scotland, UK., Piras M; Kosterlitz Centre for Therapeutics, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, Scotland, UK. m.zanda@abdn.ac.uk., Dall'Angelo S; Kosterlitz Centre for Therapeutics, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, Scotland, UK. m.zanda@abdn.ac.uk., Spinaci A; Kosterlitz Centre for Therapeutics, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, Scotland, UK. m.zanda@abdn.ac.uk., Pertwee RG; Kosterlitz Centre for Therapeutics, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, Scotland, UK. m.zanda@abdn.ac.uk., Wyllie DJ; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, EH8 9XD, Scotland, UK., Hardingham GE; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, EH8 9XD, Scotland, UK., Zanda M; Kosterlitz Centre for Therapeutics, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, Scotland, UK. m.zanda@abdn.ac.uk and C.N.R. - I.C.R.M., via Mancinelli 7, 20131 Milan, Italy.

المصدر: Organic & biomolecular chemistry [Org Biomol Chem] 2017 Mar 01; Vol. 15 (9), pp. 2086-2096.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Print Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: PubMed not MEDLINE

المؤلفون: Livesey MR; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, EH8 9XD, UK.; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, EH16 4SB, UK., Magnani D; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, EH16 4SB, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK.; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4SB, UK., Hardingham GE; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, EH8 9XD, UK.; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, EH16 4SB, UK., Chandran S; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, EH16 4SB, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK.; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4SB, UK.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, 560065, India., Wyllie DJ; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, EH8 9XD, UK.; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, EH16 4SB, UK.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, 560065, India.

المصدر: The Journal of physiology [J Physiol] 2016 Nov 15; Vol. 594 (22), pp. 6573-6582. Date of Electronic Publication: 2015 Dec 30.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Action Potentials/*physiology , Pluripotent Stem Cells/*physiology, Animals ; Cell Differentiation/physiology ; Humans ; Neurons ; Pluripotent Stem Cells/metabolism ; Transcription Factors/metabolism

المؤلفون: Perkins EM; The Centre for Integrative Physiology, The University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, UK., Suminaite D; The Centre for Integrative Physiology, The University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, UK., Clarkson YL; The Centre for Integrative Physiology, The University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, UK., Lee SK; The Centre for Integrative Physiology, The University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, UK., Lyndon AR; School of Energy, Geoscience, Infrastructure and Society, Heriot-Watt University, John Muir Building, Riccarton, Edinburgh, UK., Rothstein JD; Department of Neurology and Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, MD, USA., Wyllie DJ; The Centre for Integrative Physiology, The University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, UK.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India, Tanaka K; Laboratory of Molecular Neuroscience, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-Ku, Tokyo, Japan., Jackson M; The Centre for Integrative Physiology, The University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, UK.

المصدر: Human molecular genetics [Hum Mol Genet] 2016 Oct 15; Vol. 25 (20), pp. 4448-4461.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal*, Cerebellar Ataxia/*metabolism , Excitatory Amino Acid Transporter 1/*metabolism , Excitatory Amino Acid Transporter 4/*metabolism , Purkinje Cells/*metabolism , Spectrin/*metabolism , Spinocerebellar Ataxias/*metabolism, Animals ; Cerebellar Ataxia/genetics ; Cerebellar Ataxia/pathology ; Excitatory Amino Acid Transporter 1/physiology ; Excitatory Amino Acid Transporter 4/physiology ; Female ; Male ; Mice ; Mice, Knockout ; Phenotype ; Purkinje Cells/pathology ; Spectrin/physiology ; Spinocerebellar Ataxias/genetics ; Spinocerebellar Ataxias/pathology

SCR Disease Name: Autosomal Recessive Cerebellar Ataxia Type 1

المؤلفون: Qiu J; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom., McQueen J; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom., Bilican B; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Dando O; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, National Centre for Biological Sciences, Bangalore, India., Magnani D; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Punovuori K; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Selvaraj BT; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Livesey M; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom., Haghi G; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom.; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Heron S; School of Informatics, University of Edinburgh, Edinburgh, United Kingdom., Burr K; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Patani R; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Rajan R; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom.; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Sheppard O; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom., Kind PC; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, National Centre for Biological Sciences, Bangalore, India., Simpson TI; School of Informatics, University of Edinburgh, Edinburgh, United Kingdom., Tybulewicz VL; The Francis Crick Institute, London, United Kingdom.; Imperial College, London, United Kingdom., Wyllie DJ; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom., Fisher EM; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom., Lowell S; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Chandran S; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, National Centre for Biological Sciences, Bangalore, India., Hardingham GE; School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom.

المصدر: ELife [Elife] 2016 Oct 01; Vol. 5. Date of Electronic Publication: 2016 Oct 01.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Biological Evolution* , Gene Expression Regulation, Developmental* , Transcription, Genetic*, Neural Stem Cells/*physiology , Neurons/*physiology, Animals ; Cells, Cultured ; Humans ; Mice

المؤلفون: Livesey MR; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, United Kingdom., Magnani D; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Cleary EM; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Vasistha NA; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, United Kingdom., James OT; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, Karnataka, India., Selvaraj BT; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Burr K; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Story D; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom., Shaw CE; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, United Kingdom., Kind PC; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, Karnataka, India., Hardingham GE; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom., Wyllie DJ; Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, Karnataka, India., Chandran S; Euan MacDonald Centre for MND Research, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, Karnataka, India.

المصدر: Stem cells (Dayton, Ohio) [Stem Cells] 2016 Apr; Vol. 34 (4), pp. 1040-53. Date of Electronic Publication: 2016 Jan 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*physiopathology , Cell Differentiation/*genetics , Multiple Sclerosis/*physiopathology , Oligodendroglia/*physiology , Pluripotent Stem Cells/*physiology, Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/pathology ; Animals ; Electrophysiological Phenomena ; Female ; Humans ; Male ; Multiple Sclerosis/genetics ; Mutation ; Neurogenesis/genetics ; Neurogenesis/physiology ; Oligodendroglia/pathology ; Pluripotent Stem Cells/pathology ; Potassium Channels, Voltage-Gated/genetics ; Voltage-Gated Sodium Channels/genetics

المؤلفون: Barnes SA; Centre for Integrative Physiology and Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom., Wijetunge LS; Centre for Integrative Physiology and Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom, Interdisciplinary Institute for Neuroscience, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5297, University of Bordeaux, Bordeaux 33077, France., Jackson AD; Centre for Integrative Physiology and Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom, Centre for Brain Development and Repair, inStem, Bangalore 560065, India., Katsanevaki D; Centre for Integrative Physiology and Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom., Osterweil EK; Centre for Integrative Physiology and Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom, Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, and., Komiyama NH; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh EH16 4SB, United Kingdom., Grant SG; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh EH16 4SB, United Kingdom., Bear MF; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, and., Nägerl UV; Interdisciplinary Institute for Neuroscience, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5297, University of Bordeaux, Bordeaux 33077, France, valentin.nagerl@u-bordeaux2.fr p.kind@ed.ac.uk david.j.a.wyllie@ed.ac.uk., Kind PC; Centre for Integrative Physiology and Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom, Centre for Brain Development and Repair, inStem, Bangalore 560065, India, valentin.nagerl@u-bordeaux2.fr p.kind@ed.ac.uk david.j.a.wyllie@ed.ac.uk., Wyllie DJ; Centre for Integrative Physiology and Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom, Centre for Brain Development and Repair, inStem, Bangalore 560065, India, valentin.nagerl@u-bordeaux2.fr p.kind@ed.ac.uk david.j.a.wyllie@ed.ac.uk.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2015 Nov 11; Vol. 35 (45), pp. 15073-81.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Fragile X Mental Retardation Protein/*biosynthesis , Hippocampus/*metabolism , Hippocampus/*physiopathology , ras GTPase-Activating Proteins/*biosynthesis, Animals ; Dendritic Spines/metabolism ; Dendritic Spines/pathology ; Excitatory Postsynaptic Potentials/physiology ; Fragile X Mental Retardation Protein/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Organ Culture Techniques ; ras GTPase-Activating Proteins/genetics

المؤلفون: Till SM; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Integrative Physiology, The University of Edinburgh, Edinburgh EH8 9XD, UK., Asiminas A; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Cognitive and Neural Systems, The University of Edinburgh, Edinburgh EH8 9JZ, UK., Jackson AD; Centre for Integrative Physiology, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Brain Development and Repair, The Institute for Stem Cell Biology and Regenerative Medicine, Bangalore 560065, India., Katsanevaki D; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Integrative Physiology, The University of Edinburgh, Edinburgh EH8 9XD, UK., Barnes SA; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Integrative Physiology, The University of Edinburgh, Edinburgh EH8 9XD, UK., Osterweil EK; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Integrative Physiology, The University of Edinburgh, Edinburgh EH8 9XD, UK, Department of Brain and Cognitive Sciences, Howard Hughes Medical Institute, Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge MA 02139, USA and., Bear MF; Department of Brain and Cognitive Sciences, Howard Hughes Medical Institute, Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge MA 02139, USA and., Chattarji S; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Brain Development and Repair, The Institute for Stem Cell Biology and Regenerative Medicine, Bangalore 560065, India, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore 560065, India., Wood ER; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Cognitive and Neural Systems, The University of Edinburgh, Edinburgh EH8 9JZ, UK., Wyllie DJ; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Integrative Physiology, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Brain Development and Repair, The Institute for Stem Cell Biology and Regenerative Medicine, Bangalore 560065, India., Kind PC; Patrick Wild Centre, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Integrative Physiology, The University of Edinburgh, Edinburgh EH8 9XD, UK, Centre for Brain Development and Repair, The Institute for Stem Cell Biology and Regenerative Medicine, Bangalore 560065, India, pkind@ed.ac.uk.

المصدر: Human molecular genetics [Hum Mol Genet] 2015 Nov 01; Vol. 24 (21), pp. 5977-84. Date of Electronic Publication: 2015 Aug 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal*, Fragile X Syndrome/*physiopathology , Hippocampus/*physiopathology, Animals ; Female ; Fragile X Mental Retardation Protein/genetics ; Fragile X Mental Retardation Protein/metabolism ; Fragile X Syndrome/genetics ; Gene Knockout Techniques ; Hippocampus/pathology ; Male ; Maze Learning ; Memory Disorders/genetics ; Memory Disorders/physiopathology ; Neuronal Plasticity ; Pyramidal Cells/pathology ; Rats ; Rats, Sprague-Dawley ; Species Specificity

المؤلفون: Bell KF; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Al-Mubarak B; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Martel MA; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., McKay S; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Wheelan N; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Hasel P; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Márkus NM; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Baxter P; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Deighton RF; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Serio A; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4SB, UK., Bilican B; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4SB, UK., Chowdhry S; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Meakin PJ; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Ashford ML; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Wyllie DJ; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK., Scannevin RH; Biogen Idec, 14 Cambridge Center, Cambridge, Massachusetts 02142, USA., Chandran S; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4SB, UK., Hayes JD; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Hardingham GE; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.

المصدر: Nature communications [Nat Commun] 2015 May 13; Vol. 6, pp. 7066. Date of Electronic Publication: 2015 May 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antioxidants/*metabolism , Cerebral Cortex/*cytology , Epigenesis, Genetic/*physiology , Gene Expression Regulation, Developmental/*physiology , NF-E2-Related Factor 2/*metabolism , Neurons/*physiology, Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Cerebral Cortex/embryology ; Cytoskeletal Proteins/genetics ; Cytoskeletal Proteins/metabolism ; Electrophysiological Phenomena ; Kelch-Like ECH-Associated Protein 1 ; Mice ; Mice, Knockout ; NF-E2-Related Factor 2/genetics