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المؤلفون: Fauser F; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Kadam BN; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Arangundy-Franklin S; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Davis JE; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Vaidya V; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Schmidt NJ; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Lew G; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Xia DF; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Mureli R; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Ng C; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Zhou Y; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Scarlott NA; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Eshleman J; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Bendaña YR; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Shivak DA; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Reik A; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Li P; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Davis GD; Sangamo Therapeutics, Inc., Brisbane, CA, USA., Miller JC; Sangamo Therapeutics, Inc., Brisbane, CA, USA. jmiller@sangamo.com.

المصدر: Nature communications [Nat Commun] 2024 Feb 15; Vol. 15 (1), pp. 1181. Date of Electronic Publication: 2024 Feb 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Editing* , Cytidine Deaminase*/genetics , Cytidine Deaminase*/metabolism, Humans ; DNA/metabolism ; Zinc Fingers ; Cytidine/genetics ; CRISPR-Cas Systems

المؤلفون: Miller JC; Sangamo Therapeutics, Inc., Richmond, CA, USA., Patil DP; Sangamo Therapeutics, Inc., Richmond, CA, USA., Xia DF; Sangamo Therapeutics, Inc., Richmond, CA, USA., Paine CB; Sangamo Therapeutics, Inc., Richmond, CA, USA., Fauser F; Sangamo Therapeutics, Inc., Richmond, CA, USA., Richards HW; Sangamo Therapeutics, Inc., Richmond, CA, USA., Shivak DA; Sangamo Therapeutics, Inc., Richmond, CA, USA., Bendaña YR; Sangamo Therapeutics, Inc., Richmond, CA, USA., Hinkley SJ; Sangamo Therapeutics, Inc., Richmond, CA, USA., Scarlott NA; Sangamo Therapeutics, Inc., Richmond, CA, USA., Lam SC; Sangamo Therapeutics, Inc., Richmond, CA, USA., Reik A; Sangamo Therapeutics, Inc., Richmond, CA, USA., Zhou Y; Sangamo Therapeutics, Inc., Richmond, CA, USA., Paschon DE; Sangamo Therapeutics, Inc., Richmond, CA, USA., Li P; Sangamo Therapeutics, Inc., Richmond, CA, USA., Wangzor T; Sangamo Therapeutics, Inc., Richmond, CA, USA., Lee G; Sangamo Therapeutics, Inc., Richmond, CA, USA., Zhang L; Sangamo Therapeutics, Inc., Richmond, CA, USA., Rebar EJ; Sangamo Therapeutics, Inc., Richmond, CA, USA. erebar@sangamo.com.

المصدر: Nature biotechnology [Nat Biotechnol] 2019 Aug; Vol. 37 (8), pp. 945-952. Date of Electronic Publication: 2019 Jul 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: DNA Cleavage* , T-Lymphocytes*, Gene Editing/*methods, Base Sequence ; DNA/genetics ; DNA/metabolism ; Flow Cytometry ; Hematopoietic Stem Cells ; Humans ; K562 Cells ; Protein Domains ; RNA, Messenger

المؤلفون: Paschon DE; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Lussier S; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Wangzor T; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Xia DF; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Li PW; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Hinkley SJ; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Scarlott NA; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Lam SC; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Waite AJ; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Truong LN; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Gandhi N; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Kadam BN; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Patil DP; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Shivak DA; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Lee GK; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Holmes MC; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Zhang L; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Miller JC; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA., Rebar EJ; Sangamo Therapeutics, Inc., 501 Canal Boulevard, Suite A100, Richmond, California, 94804, USA. erebar@sangamo.com.

المصدر: Nature communications [Nat Commun] 2019 Mar 08; Vol. 10 (1), pp. 1133. Date of Electronic Publication: 2019 Mar 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Genome, Human*, Deoxyribonucleases, Type II Site-Specific/*genetics , Gene Editing/*methods , Protein Engineering/*methods , Zinc Finger Nucleases/*genetics, Base Pairing ; Base Sequence ; DNA-Directed RNA Polymerases/genetics ; DNA-Directed RNA Polymerases/metabolism ; Deoxyribonucleases, Type II Site-Specific/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Genetic Loci ; Genomic Library ; Humans ; INDEL Mutation ; K562 Cells ; Peptide Library ; Plasmids/chemistry ; Plasmids/metabolism ; Transformation, Genetic ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Zinc Finger Nucleases/metabolism

المؤلفون: Oakes BL; The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA., Xia DF; Sangamo BioSciences Inc., Richmond, California 94804, USA., Rowland EF; The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA., Xu DJ; The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA., Ankoudinova I; Sangamo BioSciences Inc., Richmond, California 94804, USA., Borchardt JS; Sangamo BioSciences Inc., Richmond, California 94804, USA., Zhang L; Sangamo BioSciences Inc., Richmond, California 94804, USA., Li P; Sangamo BioSciences Inc., Richmond, California 94804, USA., Miller JC; Sangamo BioSciences Inc., Richmond, California 94804, USA., Rebar EJ; Sangamo BioSciences Inc., Richmond, California 94804, USA., Noyes MB; The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.; Institute for Systems Genetics, NYU School of Medicine, New York, New York 10016, USA.; Department of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, New York 10016, USA.

المصدر: Nature communications [Nat Commun] 2016 Jan 07; Vol. 7, pp. 10194. Date of Electronic Publication: 2016 Jan 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Zinc Fingers*, Deoxyribonucleases/*metabolism , Gene Expression Regulation, Enzymologic/*physiology , Receptors, CCR5/*metabolism, Animals ; DNA-Binding Proteins/genetics ; Deoxyribonucleases/genetics ; Genes, Reporter ; Genome ; Humans ; Peptide Library ; Receptors, CCR2/metabolism

المؤلفون: Miller JC; Sangamo BioSciences Inc., Richmond, California, USA., Zhang L; Sangamo BioSciences Inc., Richmond, California, USA., Xia DF; Sangamo BioSciences Inc., Richmond, California, USA., Campo JJ; Sangamo BioSciences Inc., Richmond, California, USA., Ankoudinova IV; Sangamo BioSciences Inc., Richmond, California, USA., Guschin DY; Sangamo BioSciences Inc., Richmond, California, USA., Babiarz JE; Sangamo BioSciences Inc., Richmond, California, USA., Meng X; Sangamo BioSciences Inc., Richmond, California, USA., Hinkley SJ; Sangamo BioSciences Inc., Richmond, California, USA., Lam SC; Sangamo BioSciences Inc., Richmond, California, USA., Paschon DE; Sangamo BioSciences Inc., Richmond, California, USA., Vincent AI; Sangamo BioSciences Inc., Richmond, California, USA., Dulay GP; Sangamo BioSciences Inc., Richmond, California, USA., Barlow KA; Sangamo BioSciences Inc., Richmond, California, USA., Shivak DA; Sangamo BioSciences Inc., Richmond, California, USA., Leung E; Sangamo BioSciences Inc., Richmond, California, USA., Kim JD; Sangamo BioSciences Inc., Richmond, California, USA., Amora R; Sangamo BioSciences Inc., Richmond, California, USA., Urnov FD; Sangamo BioSciences Inc., Richmond, California, USA., Gregory PD; Sangamo BioSciences Inc., Richmond, California, USA., Rebar EJ; Sangamo BioSciences Inc., Richmond, California, USA.

المصدر: Nature methods [Nat Methods] 2015 May; Vol. 12 (5), pp. 465-71. Date of Electronic Publication: 2015 Mar 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE

مواضيع طبية MeSH: Genome*, Gene Expression Regulation/*physiology , RNA Editing/*physiology , Transcription Factors/*metabolism, Animals ; Base Sequence ; DNA/genetics ; Enzyme-Linked Immunosorbent Assay ; Genetic Markers ; Transcription Factors/genetics

المؤلفون: Miller JC; Sangamo BioSciences, Inc., Richmond, California, USA., Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ

المصدر: Nature biotechnology [Nat Biotechnol] 2011 Feb; Vol. 29 (2), pp. 143-8. Date of Electronic Publication: 2010 Dec 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Engineering*, Combinatorial Chemistry Techniques/*methods , Mutagenesis, Site-Directed/*methods , Transcription Factors/*genetics , Transcription Factors/*metabolism, Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Base Sequence ; Binding Sites ; DNA/genetics ; DNA/metabolism ; Deoxyribonucleases, Type II Site-Specific/genetics ; Deoxyribonucleases, Type II Site-Specific/metabolism ; Genome ; Humans ; K562 Cells ; Molecular Sequence Data ; Receptors, CCR5/genetics ; Vascular Endothelial Growth Factor A/genetics ; Xanthomonas

المؤلفون: Doyon Y; Sangamo BioSciences, Richmond, California, USA. ydoyon@sangamo.com, Vo TD, Mendel MC, Greenberg SG, Wang J, Xia DF, Miller JC, Urnov FD, Gregory PD, Holmes MC

المصدر: Nature methods [Nat Methods] 2011 Jan; Vol. 8 (1), pp. 74-9. Date of Electronic Publication: 2010 Dec 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE

مواضيع طبية MeSH: Endonucleases/*metabolism , Zinc Fingers/*physiology, DNA/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Dimerization ; Endonucleases/genetics ; Genome ; Saccharomyces cerevisiae/enzymology ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Zinc Fingers/genetics