المؤلفون: MB Long, AJ Brenes, AJM Howden, HR Keir, C Rollings, YH Giam, T Pembridge, L Delgado, H Abo-Leyah, A Lloyd, G Sollberger, RC Hull, A Gilmour, C Hughes, S Gallant, DM Cassidy, BJM New, D Connell, H Richardson, A Shoemark, AI Lamond, DA Cantrell, JD Chalmers

المصدر: Joint BTS/BALR/A+L UK Early Career Investigator Symposium.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f321e2cff84a03918b92336e10e3fb23
https://doi.org/10.1136/thorax-2022-btsabstracts.3

المؤلفون: MB Long, H Abo-Leyah, YH Giam, T Vadiveloo, RC Hull, HR Keir, T Pembridge, D Alferes de Lima, BJM New, S Inglis, A Gilmour, C Hughes, L Delgado, G MacLennan, AT Dinkova-Kostova, JD Chalmers

المصدر: ‘The fast and the furious’ – Clinical studies in COVID-19.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f139f8d29397de5f542168f2216182dc
https://doi.org/10.1136/thorax-2022-btsabstracts.49

المؤلفون: Perea L; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Biomedical Research Institute August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Bottier M; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, National Heart and Lung Institute, Imperial College London, London, UK., Cant E; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Richardson H; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Dicker AJ; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Shuttleworth M; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Giam YH; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Abo-Leyah H; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Finch S; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Huang JT; Division of Systems Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Shteinberg M; Pulmonology Institute and CF Center, Carmel Medical Center, Haifa, Israel., Goeminne PC; AZNikolaas, Sint-Niklaas, Belgium., Polverino E; Vall d'Hebron University Hospital, Barcelona, Spain., Altenburg J; Amsterdam UMC, Amsterdam, The Netherlands., Blasi F; Department of Pathophysiology and Transplantation, Università Degli Studi Di Milano, Milan, Italy.; Department of Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Center, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano, Milan, Italy., Welte T; Department of Respiratory Medicine, Medizinische Hochschule Hannover, Hannover, Germany., Aliberti S; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; IRCCS Humanitas Research Hospital, Respiratory Unit, Milan, Italy., Sibila O; Respiratory Department, Hospital Clinic, IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain., Chalmers JD; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Senior authors contributed equally to this manuscript., Shoemark A; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK a.shoemark@dundee.ac.uk.; Senior authors contributed equally to this manuscript.

المصدر: The European respiratory journal [Eur Respir J] 2024 Aug 15; Vol. 64 (2). Date of Electronic Publication: 2024 Aug 15 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE

مواضيع طبية MeSH: Interleukin-1beta*/metabolism , Bronchiectasis*/physiopathology , Bronchiectasis*/metabolism , Bronchiectasis*/microbiology , Sputum*/metabolism , Mucociliary Clearance* , Severity of Illness Index*, Humans ; Female ; Male ; Middle Aged ; Aged ; Inflammasomes/metabolism ; Mucus/metabolism ; Caspase 1/metabolism ; Microbiota ; Inflammation ; Cohort Studies ; RNA, Ribosomal, 16S/genetics ; Adult ; Cilia/metabolism

المؤلفون: Long MB; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom., Gilmour A; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom., Kehl M; Vaccine and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., Tabor DE; Vaccine and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., Keller AE; Vaccine and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., Warrener P; Vaccine and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., Gopalakrishnan V; Vaccine and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., Rosengren S; Translational Science and Experimental Medicine, Respiratory & Immunology, Respiratory and Immunology, and., Crichton ML; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom., McIntosh E; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom., Giam YH; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom., Keir HR; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom., Brailsford W; Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden; and., Hughes R; Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Belvisi MG; Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden; and., Sellman BR; Vaccine and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., DiGiandomenico A; Vaccine and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., Chalmers JD; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.

المصدر: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Jul 01; Vol. 210 (1), pp. 35-46.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE

مواضيع طبية MeSH: Bronchiectasis*/immunology , Bronchiectasis*/microbiology , Pseudomonas aeruginosa*/immunology , Neutrophils*/immunology , Neutrophils*/drug effects , Antibodies, Bispecific*/therapeutic use , Antibodies, Bispecific*/pharmacology , Pseudomonas Infections*/immunology, Humans ; Female ; Male ; Middle Aged ; Aged ; Adult ; Antigens, Bacterial ; Bacterial Toxins ; Pore Forming Cytotoxic Proteins

المؤلفون: Gilmour A; Molecular and Clinical Medicine, University of Dundee, Dundee, UK.; These authors contributed equally., Hughes C; Molecular and Clinical Medicine, University of Dundee, Dundee, UK.; These authors contributed equally., Giam YH; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Hull RC; Molecular and Clinical Medicine, University of Dundee, Dundee, UK.; University of Sheffield, Sheffield, UK., Pembridge T; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Abo-Leyah H; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Thompson AAR; University of Sheffield, Sheffield, UK., Condliffe AM; University of Sheffield, Sheffield, UK., Shoemark A; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Chalmers JD; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Long MB; Molecular and Clinical Medicine, University of Dundee, Dundee, UK.

المصدر: ERJ open research [ERJ Open Res] 2024 Jun 17; Vol. 10 (3). Date of Electronic Publication: 2024 Jun 17 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE

المؤلفون: Long MB; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; These authors contributed equally., Abo-Leyah H; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; These authors contributed equally., Giam YH; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Vadiveloo T; Centre for Healthcare Randomised Trials, University of Aberdeen, Aberdeen, UK., Hull RC; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, UK., Keir HR; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Pembridge T; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Alferes De Lima D; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Delgado L; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Inglis SK; Tayside Clinical Trials Unit, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Hughes C; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Gilmour A; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Gierlinski M; Computational Biology, School of Life Sciences, University of Dundee, Dundee, UK., New BJM; NHS Tayside, Ninewells Hospital, Dundee, UK., MacLennan G; Centre for Healthcare Randomised Trials, University of Aberdeen, Aberdeen, UK., Dinkova-Kostova AT; Division of Cellular and Systems Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Department of Pharmacology and Molecular Sciences and Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chalmers JD; Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

المصدر: ERJ open research [ERJ Open Res] 2024 Mar 11; Vol. 10 (2). Date of Electronic Publication: 2024 Mar 11 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE

المؤلفون: Long MB; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.; Indicates equal contribution., Howden AJM; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.; Indicates equal contribution., Keir HR; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.; Indicates equal contribution., Rollings CM; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.; Indicates equal contribution., Giam YH; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Pembridge T; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Delgado L; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Abo-Leyah H; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Lloyd AF; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK., Sollberger G; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.; Max Planck Institute for Infection Biology, Berlin, Germany., Hull R; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Gilmour A; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Hughes C; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., New BJM; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Cassidy D; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Shoemark A; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Richardson H; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Lamond AI; Division of Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, UK., Cantrell DA; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK., Chalmers JD; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK j.chalmers@dundee.ac.uk.; Indicates joint senior authorship., Brenes AJ; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.; Division of Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, UK.; Indicates joint senior authorship.

المصدر: The European respiratory journal [Eur Respir J] 2024 Mar 07; Vol. 63 (3). Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).

نوع المنشور: Observational Study; Journal Article

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*, Humans ; SARS-CoV-2 ; Neutrophils ; Proteome ; Cytokines

المؤلفون: Choi H; Division of Molecular and Clinical Medicine and.; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Republic of Korea., Ryu S; Biostatistical Consulting and Research Lab, Medical Research Collaborating Center, Hanyang University, Seoul, Republic of Korea., Keir HR; Division of Molecular and Clinical Medicine and., Giam YH; Division of Molecular and Clinical Medicine and., Dicker AJ; Division of Molecular and Clinical Medicine and., Perea L; Division of Molecular and Clinical Medicine and., Richardson H; Division of Molecular and Clinical Medicine and., Huang JTJ; Division of Systems Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., Cant E; Division of Molecular and Clinical Medicine and., Blasi F; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Pollock J; Division of Molecular and Clinical Medicine and., Shteinberg M; Pulmonology Institute and CF Center, Carmel Medical Center and the Technion-Israel Institute of Technology, Haifa, Israel., Finch S; Division of Molecular and Clinical Medicine and., Aliberti S; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Respiratory Unit, IRCCS Humanitas Research Hospital, Milan, Italy; and., Sibila O; Respiratory Department, Hospital Clínic, IDIBAPS, CIBERES, Universitat de Barcelona, Barcelona, Spain., Shoemark A; Division of Molecular and Clinical Medicine and., Chalmers JD; Division of Molecular and Clinical Medicine and.

المصدر: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2023 Dec 01; Vol. 208 (11), pp. 1166-1176.

نوع المنشور: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE

مواضيع طبية MeSH: Bronchiectasis*/microbiology, Humans ; Female ; Aged ; Male ; Biomarkers ; Sputum/microbiology ; Inflammation ; Cohort Studies

المؤلفون: Keir HR; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Long MB; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Abo-Leyah H; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Giam YH; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Vadiveloo T; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., Pembridge T; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Hull RC; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Delgado L; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Band M; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., McLaren-Neil F; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Adamson S; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Lahnsteiner E; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Gilmour A; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Hughes C; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., New BJ; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Connell D; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Dowey R; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Turton H; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Richardson H; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Cassidy D; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Cooper J; NHS Grampian, Aberdeen, UK., Suntharalingam J; Royal United Hospitals, Bath, UK., Diwakar L; University Hospital North Midlands, Stoke-on-Trent, UK., Russell P; Princess Alexandria Hospital, Harlow, UK., Underwood J; Cardiff & Vale University Health Board, Cardiff, UK., Hicks A; Portsmouth Hospitals NHS Trust, Portsmouth, UK., Dosanjh DP; University Hospitals Birmingham, Birmingham, UK., Sage B; NHS Highland, Inverness, UK., Dhasmana D; NHS Fife, Kirkcaldy, UK., Spears M; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Thompson AR; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Brightling C; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Smith A; NHS Lanarkshire, Wishaw, UK., Patel M; NHS Lanarkshire, Wishaw, UK., George J; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Condliffe AM; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Shoemark A; Molecular and Clinical Medicine, University of Dundee, Dundee, UK., MacLennan G; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., Chalmers JD; Molecular and Clinical Medicine, University of Dundee, Dundee, UK. Electronic address: jchalmers@dundee.ac.uk.

مؤلفون مشاركون: STOP-COVID19 Investigators

المصدر: The Lancet. Respiratory medicine [Lancet Respir Med] 2022 Dec; Vol. 10 (12), pp. 1119-1128. Date of Electronic Publication: 2022 Sep 05.

نوع المنشور: Randomized Controlled Trial; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19 Drug Treatment* , Cathepsin C*/antagonists & inhibitors, Humans ; Double-Blind Method ; Serine Proteases ; Treatment Outcome

المؤلفون: Giam YH; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Shoemark A; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Chalmers JD; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK jchalmers@dundee.ac.uk.

المصدر: The European respiratory journal [Eur Respir J] 2021 Aug 26; Vol. 58 (2). Date of Electronic Publication: 2021 Aug 26 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE

مواضيع طبية MeSH: Bronchiectasis* , Extracellular Traps*, Humans ; Inflammation ; Neutrophils ; Severity of Illness Index