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1
المؤلفون: Usha R. Patel, Richard M. Nelson, Gerald Nabozny, Christian Harcken, Zhidong Chen, Ljiljana Zuvela-Jelaska, Donald Souza, Todd Bosanac, Alison Kukulka, Mita Patel, Thomas Wai-Ho Lee, Doris Riether, Mark Stephen Ralph, David S. Thomson, Tazmeen Fadra-Khan, Yancey David Ward, Hossein Razavi, Pingrong Liu
المصدر: ACS Medicinal Chemistry Letters. 5:1318-1323
مصطلحات موضوعية: Drug, Nonsteroidal, biology, Chemistry, media_common.quotation_subject, Organic Chemistry, hERG, Cytochrome P450, Metabolic stability, Pharmacology, Biochemistry, chemistry.chemical_compound, Drug Discovery, Aqueous solubility, biology.protein, medicine, Ion channel, Glucocorticoid, media_common, medicine.drug
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2
المؤلفون: Kathy Crane, Michel J. Emmanuel, Younes Bekkali, Richard M. Nelson, Alison Kukulka, Denice M. Spero, Erick R. R. Young, Eugene R. Hickey, Usha R. Patel, Jessi Wildeson, Ming-Hong Hao, Weimin Liu, Raj Betageri, Yancey David Ward, Della White, David S. Thomson, Mark E. Labadia, Dorothy M. Freeman, Maryanne L. Brown
المصدر: Bioorganic & Medicinal Chemistry Letters. 17:2465-2469
مصطلحات موضوعية: Pyrrolidines, medicine.drug_class, Stereochemistry, Chemistry, Pharmaceutical, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Pyrrolidine, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Catalytic Domain, Nitriles, Drug Discovery, medicine, Humans, Structure–activity relationship, Molecular Biology, Cathepsin S, chemistry.chemical_classification, Cathepsin, biology, Organic Chemistry, Dipeptides, Cathepsins, Enzyme, Models, Chemical, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Peptides
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3
المؤلفون: Yancey David Ward, Vittorio Farina
المصدر: Tetrahedron Letters. 37:6993-6996
مصطلحات موضوعية: chemistry.chemical_classification, Primary (chemistry), Aryl, Organic Chemistry, chemistry.chemical_element, Cleavage (embryo), Biochemistry, Catalysis, chemistry.chemical_compound, Solid-phase synthesis, chemistry, Drug Discovery, Organic chemistry, Amination, Alkyl, Palladium
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4
المؤلفون: Neil Moss, Racheline Schwartz, Erick R. R. Young, Michael J. Burke, Eugene R. Hickey, Matthew R. Netherton, Raj Nagaraja, Yancey David Ward, Alexander Heim-Riether, Kathleen Haverty, Derek Cogan, Daw-Tsun Shih, Philip D. Ramsden, Qing Zhang, Gao Donghong A, Zhaoming Xiong, Kathy O’Shea
المصدر: Bioorganicmedicinal chemistry letters. 22(23)
مصطلحات موضوعية: Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Triazole, Pharmaceutical Science, Thiophenes, Metabolic stability, Triazoles, Biochemistry, Amides, Cathepsins, chemistry.chemical_compound, Structure-Activity Relationship, Amide, Drug Discovery, Microsomes, Liver, Molecular Medicine, Humans, Protease Inhibitors, Molecular Biology, Cathepsin S, Half-Life, Protein Binding
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5
المؤلفون: Leslie Martin, Brian Werneburg, Lori Patnaude, Wu Jiang-Ping, Roger J. Snow, Andre White, Neil Moss, Donna Skow, Wang Mao, Mohammed A. Kashem, Denise Andersen, Usha R. Patel, Asitha Abeywardane, Ji Wang, Tina Morwick, Yancey David Ward, Gregory W. Peet, Christopher Pargellis, Daniel R. Goldberg, Michel J. Emmanuel, Susan Lukas, Elda Gautschi
المصدر: Bioorganicmedicinal chemistry letters. 17(16)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Protein Serine-Threonine Kinases, Biochemistry, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Transferase, Structure–activity relationship, Molecular Biology, chemistry.chemical_classification, Protein-Serine-Threonine Kinases, biology, Molecular Structure, Organic Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Intracellular Signaling Peptides and Proteins, In vitro, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Lactam, Molecular Medicine, Hinge region, Carbolines
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6
المؤلفون: Doris Riether, Yancey David Ward, David S. Thomson, Christian Harcken
المصدر: ChemInform. 37
مصطلحات موضوعية: Chemistry, Organic Chemistry, Organic chemistry, General Medicine, Combinatorial chemistry