المؤلفون: Hewitt RJ; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, SW3 6NP, UK., Puttur F; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Gaboriau DCA; Facility for Imaging by Light Microscopy, National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Fercoq F; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Fresquet M; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK., Traves WJ; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Yates LL; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Walker SA; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Molyneaux PL; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, SW3 6NP, UK., Kemp SV; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, SW3 6NP, UK.; Department of Respiratory Medicine, Nottingham University Hospitals NHS Trust, City Campus, Hucknall Road, Nottingham, NG5 1PB, UK., Nicholson AG; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, SW3 6NP, UK., Rice A; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, SW3 6NP, UK., Roberts E; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Lennon R; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK., Carlin LM; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Byrne AJ; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Maher TM; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.; Keck Medicine of USC, 1510 San Pablo Street, Los Angeles, CA, 90033, USA., Lloyd CM; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK. c.lloyd@imperial.ac.uk.

المصدر: Nature communications [Nat Commun] 2023 Sep 27; Vol. 14 (1), pp. 6039. Date of Electronic Publication: 2023 Sep 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Idiopathic Pulmonary Fibrosis*, Humans ; Extracellular Matrix ; Alveolar Epithelial Cells ; Biological Transport ; Cell Movement ; Keratin-5

المؤلفون: Granell R; MRC Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Curtin JA; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom., Haider S; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Kitaba NT; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Mathie SA; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Gregory LG; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Yates LL; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Tutino M; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom., Hankinson J; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom., Perretti M; William Harvey Research Institute, Barts and The London School of Medicine Queen Mary University of London, London, United Kingdom., Vonk JM; Department of Epidemiology, University of Groningen, University Medical Center Groningen\, Groningen, Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, Netherlands., Arshad HS; NIHR Southampton Biomedical Research Centre, University Hospitals Southampton NHS Foundation Trust, Southampton, United Kingdom.; David Hide Asthma and Allergy Research Centre, Isle of Wight, United Kingdom.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Cullinan P; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Fontanella S; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Roberts GC; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospitals Southampton NHS Foundation Trust, Southampton, United Kingdom.; David Hide Asthma and Allergy Research Centre, Isle of Wight, United Kingdom., Koppelman GH; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, Netherlands.; Department of Pediatric Pulmonology and Pediatric Allergology, University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Groningen, Netherlands., Simpson A; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom., Turner SW; Child Health, University of Aberdeen, Aberdeen, United Kingdom., Murray CS; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom., Lloyd CM; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Holloway JW; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospitals Southampton NHS Foundation Trust, Southampton, United Kingdom., Custovic A; National Heart and Lung Institute, Imperial College London, London, United Kingdom.

مؤلفون مشاركون: UNICORN and Breathing Together investigators

المصدر: ELife [Elife] 2023 May 25; Vol. 12. Date of Electronic Publication: 2023 May 25.

نوع المنشور: Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Asthma*/genetics , Asthma*/diagnosis , Hypersensitivity*, Animals ; Mice ; Genome-Wide Association Study ; Phenotype ; Respiratory Sounds/genetics ; Annexins/genetics

المؤلفون: Leach DA; Department of Surgery and Cancer, Imperial College London, London, UK., Mohr A; School of Life Sciences, University of Essex, Colchester, Essex, UK., Giotis ES; School of Life Sciences, University of Essex, Colchester, Essex, UK.; Department of Infectious Diseases, Imperial College London, London, UK., Cil E; School of Life Sciences, University of Essex, Colchester, Essex, UK., Isac AM; School of Life Sciences, University of Essex, Colchester, Essex, UK., Yates LL; National Heart and Lung Institute, Imperial College London, London, UK., Barclay WS; Department of Infectious Diseases, Imperial College London, London, UK., Zwacka RM; School of Life Sciences, University of Essex, Colchester, Essex, UK., Bevan CL; Department of Surgery and Cancer, Imperial College London, London, UK. charlotte.bevan@imperial.ac.uk., Brooke GN; Department of Surgery and Cancer, Imperial College London, London, UK. gbrooke@essex.ac.uk.; School of Life Sciences, University of Essex, Colchester, Essex, UK. gbrooke@essex.ac.uk.

المصدر: Nature communications [Nat Commun] 2021 Jul 01; Vol. 12 (1), pp. 4068. Date of Electronic Publication: 2021 Jul 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19 Drug Treatment*, Androgen Antagonists/*pharmacology , Benzamides/*pharmacology , Nitriles/*pharmacology , Phenylthiohydantoin/*pharmacology , Serine Endopeptidases/*metabolism , Virus Internalization/*drug effects, Angiotensin-Converting Enzyme 2/chemical synthesis ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; COVID-19/metabolism ; COVID-19/virology ; Down-Regulation/drug effects ; Female ; Humans ; Lung/metabolism ; Lung/virology ; Male ; Mice ; SARS-CoV-2/drug effects ; Serine Endopeptidases/genetics

المؤلفون: Akram KM; Department of Oncology & Metabolism, University of Sheffield, Sheffield, UK., Yates LL; National Heart and Lung Institute, Imperial College London, London, UK., Mongey R; National Heart and Lung Institute, Imperial College London, London, UK., Rothery S; National Heart and Lung Institute, Imperial College London, London, UK.; Facility for Imaging by Light Microscopy, NHLI, Faculty of Medicine, Imperial College London, London, UK., Gaboriau DCA; National Heart and Lung Institute, Imperial College London, London, UK.; Facility for Imaging by Light Microscopy, NHLI, Faculty of Medicine, Imperial College London, London, UK., Sanderson J; MRC Harwell Institute, Harwell Campus, Oxfordshire, UK., Hind M; National Heart and Lung Institute, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Respiratory Biomedical Research Unit at the Royal Brompton & Harefield NHS Foundation Trust and Imperial College, London, UK., Griffiths M; National Heart and Lung Institute, Imperial College London, London, UK.; Peri-Operative Medicine Department, St Bartholomew's Hospital, London, UK., Dean CH; National Heart and Lung Institute, Imperial College London, London, UK.; MRC Harwell Institute, Harwell Campus, Oxfordshire, UK.

المصدر: Bio-protocol [Bio Protoc] 2019 Oct 20; Vol. 9 (20), pp. e3403. Date of Electronic Publication: 2019 Oct 20 (Print Publication: 2019).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bio-protocol LLC Country of Publication: United States NLM ID: 101635102 Publication Model: eCollection Cited Medium: Internet ISSN: 2331-8325 (Electronic) Linking ISSN: 23318325 NLM ISO Abbreviation: Bio Protoc Subsets: PubMed not MEDLINE

المؤلفون: Akram KM; National Heart and Lung Institute, Imperial College London, London, UK., Yates LL; National Heart and Lung Institute, Imperial College London, London, UK., Mongey R; National Heart and Lung Institute, Imperial College London, London, UK., Rothery S; Facility for Imaging by Light Microscopy, NHLI, Faculty of Medicine, Imperial College London, London, UK., Gaboriau DCA; Facility for Imaging by Light Microscopy, NHLI, Faculty of Medicine, Imperial College London, London, UK., Sanderson J; MRC Harwell Institute, Harwell Campus, Oxfordshire, UK., Hind M; National Heart and Lung Institute, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Respiratory Biomedical Research Unit at the Royal Brompton & Harefield NHS Foundation Trust and Imperial College, London, UK., Griffiths M; National Heart and Lung Institute, Imperial College London, London, UK.; Peri-Operative Medicine Department, St Bartholomew's Hospital, London, UK., Dean CH; National Heart and Lung Institute, Imperial College London, London, UK. c.dean@imperial.ac.uk.; MRC Harwell Institute, Harwell Campus, Oxfordshire, UK. c.dean@imperial.ac.uk.

المصدر: Nature communications [Nat Commun] 2019 Mar 12; Vol. 10 (1), pp. 1178. Date of Electronic Publication: 2019 Mar 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Cell Movement/*physiology , Epithelial Cells/*physiology , Organogenesis/*physiology , Pulmonary Alveoli/*embryology, Actomyosin/antagonists & inhibitors ; Actomyosin/physiology ; Animals ; Animals, Newborn ; Cell Movement/drug effects ; Cytochalasin D/pharmacology ; Epithelial Cells/drug effects ; Heterocyclic Compounds, 4 or More Rings/pharmacology ; Intravital Microscopy ; Mice ; Mice, Inbred C57BL ; Microscopy, Fluorescence ; Models, Animal ; Organogenesis/drug effects ; Pulmonary Alveoli/drug effects ; Time-Lapse Imaging

المؤلفون: Zhang Y; Genomics Medicine Section, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK y.zhang@imperial.ac.uk c.dean@imperial.ac.uk., Poobalasingam T; Inflammation, Repair and Development Section, National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Yates LL; Inflammation, Repair and Development Section, National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Walker SA; Inflammation, Repair and Development Section, National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Taylor MS; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3, 7BN., Chessum L; MRC Harwell Institute, Oxfordshire, OX11 0RD, UK., Harrison J; MRC Harwell Institute, Oxfordshire, OX11 0RD, UK., Tsaprouni L; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Adcock IM; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Lloyd CM; Inflammation, Repair and Development Section, National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Cookson WO; Genomics Medicine Section, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Moffatt MF; Genomics Medicine Section, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Dean CH; Inflammation, Repair and Development Section, National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK y.zhang@imperial.ac.uk c.dean@imperial.ac.uk.; MRC Harwell Institute, Oxfordshire, OX11 0RD, UK.

المصدر: Disease models & mechanisms [Dis Model Mech] 2018 Jan 29; Vol. 11 (1). Date of Electronic Publication: 2018 Jan 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Electronic Cited Medium: Internet ISSN: 1754-8411 (Electronic) Linking ISSN: 17548403 NLM ISO Abbreviation: Dis Model Mech Subsets: MEDLINE

مواضيع طبية MeSH: Asthma/*enzymology , Asthma/*prevention & control , Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/*metabolism, Amino Acid Sequence ; Animals ; Asthma/complications ; Asthma/pathology ; Base Sequence ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/chemistry ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/genetics ; Disease Models, Animal ; Epithelial Cells/metabolism ; Ethylnitrosourea ; Genotype ; Homozygote ; Humans ; Hypersensitivity/complications ; Hypersensitivity/pathology ; Inflammation/complications ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Lung/parasitology ; Lung/pathology ; Mice ; Mice, Mutant Strains ; Mutation/genetics ; Pyroglyphidae ; Reproducibility of Results

المؤلفون: Oozeer F; MRC Centre for Developmental Neurobiology, New Hunts House, Kings College London, London, SE1 1UL, UK., Yates LL; MRC Harwell, Oxfordshire, OX11 0RD, UK.; Department of Medicine, Imperial College London, London, SW7 2AZ, UK., Dean C; MRC Harwell, Oxfordshire, OX11 0RD, UK.; Department of Medicine, Imperial College London, London, SW7 2AZ, UK., Formstone CJ; MRC Centre for Developmental Neurobiology, New Hunts House, Kings College London, London, SE1 1UL, UK. c.formstone@herts.ac.uk.; Department of Biological and Environmental Sciences, University of Hertfordshire, College lane, Hatfield, AL10 9AB, UK. c.formstone@herts.ac.uk.

المصدر: Scientific reports [Sci Rep] 2017 May 12; Vol. 7 (1), pp. 1880. Date of Electronic Publication: 2017 May 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cell Communication* , Cell Division* , Cell Polarity* , Embryo, Mammalian*, Skin/*cytology , Skin/*metabolism, Animals ; Interphase/genetics ; Mice ; Mice, Knockout ; Mitosis/genetics ; Receptors, G-Protein-Coupled/metabolism ; Signal Transduction

المؤلفون: Poobalasingam T; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK., Yates LL; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK., Walker SA; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK., Pereira M; Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London SW3 6LR, UK., Gross NY; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK., Ali A; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK., Kolatsi-Joannou M; Developmental Biology and Cancer Unit, UCL Institute of Child Health, London WC1N 1EH, UK., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London SW7 2AZ, UK.; Center for Life Course Epidemiology, Faculty of Medicine, P.O. Box 5000, University of Oulu, Oulu FI-90014 Finland.; Biocenter Oulu, P.O. Box 5000, Aapistie 5A, University of Oulu, Oulu FI-90014, Finland.; Unit of Primary Care, Oulu University Hospital, Kajaanintie 50, P.O. Box 20, Oulu FI-90220, Finland., Pekkanen J; National Institute for Health and Welfare, Living Environment and Health Unit, Kuopio FI-70701, Finland.; University of Helsinki, Department of Public Health, Helsinki FI-00014, Finland., Papakrivopoulou E; Developmental Biology and Cancer Unit, UCL Institute of Child Health, London WC1N 1EH, UK., Long DA; Developmental Biology and Cancer Unit, UCL Institute of Child Health, London WC1N 1EH, UK., Griffiths M; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK.; National Institute for Health Research (NIHR) Respiratory Biomedical Research Unit at the Royal Brompton & Harefield NHS Foundation Trust and Imperial College, London SW3 6NP, UK., Wagner D; Comprehensive Pneumology Center, Helmholtz Center Munich, Ludwig Maximilians University Munich, Munich 81377, Germany., Königshoff M; Comprehensive Pneumology Center, Helmholtz Center Munich, Ludwig Maximilians University Munich, Munich 81377, Germany., Hind M; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK.; National Institute for Health Research (NIHR) Respiratory Biomedical Research Unit at the Royal Brompton & Harefield NHS Foundation Trust and Imperial College, London SW3 6NP, UK.; Department of Respiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London SW3 6NP, UK., Minelli C; Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London SW3 6LR, UK., Lloyd CM; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK., Dean CH; Inflammation Repair and Development Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK c.dean@imperial.ac.uk.; Mammalian Genetics Unit, MRC Harwell Institute, Didcot OX11 0RD, UK.

المصدر: Disease models & mechanisms [Dis Model Mech] 2017 Apr 01; Vol. 10 (4), pp. 409-423. Date of Electronic Publication: 2017 Feb 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1754-8411 (Electronic) Linking ISSN: 17548403 NLM ISO Abbreviation: Dis Model Mech Subsets: MEDLINE

مواضيع طبية MeSH: Cell Polarity* , Homeostasis* , Wound Healing*, Aging/*pathology , Lung/*pathology , Nerve Tissue Proteins/*genetics, A549 Cells ; Actin Cytoskeleton/metabolism ; Animals ; Cell Movement ; Down-Regulation/genetics ; Elastin/metabolism ; Embryo, Mammalian/pathology ; Gene Knockdown Techniques ; Heterozygote ; Humans ; Lung/embryology ; Lung/physiopathology ; Macrophages/pathology ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Models, Biological ; Mutation/genetics ; Phenotype ; Polymorphism, Genetic ; Pulmonary Disease, Chronic Obstructive/genetics ; Smoking/adverse effects ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism

المؤلفون: Elsum IA; Cell Cycle and Cancer Genetics, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Yates LL; Cell Cycle and Cancer Genetics, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Pearson HB; 1] Cell Cycle and Cancer Genetics, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia [2] The Sir Peter MacCallum Department of Oncology, Melbourne, Victoria, Australia., Phesse TJ; Cell Signaling and Cell Death Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Long F; Cell Cycle and Cancer Genetics, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., O'Donoghue R; Cell Signaling and Cell Death Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Ernst M; Cell Signaling and Cell Death Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Cullinane C; 1] The Sir Peter MacCallum Department of Oncology, Melbourne, Victoria, Australia [2] Translational Research Laboratory, Cancer Therapeutics Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Humbert PO; 1] Cell Cycle and Cancer Genetics, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia [2] The Sir Peter MacCallum Department of Oncology, Melbourne, Victoria, Australia [3] Department of Pathology, University of Melbourne, Parkville, Victoria, Australia [4] Department of Molecular Biology and Biochemistry, University of Melbourne, Parkville, Victoria, Australia.

المصدر: Oncogene [Oncogene] 2014 Nov 27; Vol. 33 (48), pp. 5523-33. Date of Electronic Publication: 2013 Nov 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung/*genetics , Cell Transformation, Neoplastic/*genetics , Lung Neoplasms/*genetics , Membrane Proteins/*genetics , Proto-Oncogene Proteins/*genetics , Tumor Suppressor Proteins/*genetics , ras Proteins/*genetics, Animals ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Disease Models, Animal ; Disease Progression ; Enzyme Activation ; Gene Dosage ; Heterozygote ; Humans ; Immunoblotting ; Immunohistochemistry ; Intracellular Signaling Peptides and Proteins/genetics ; Loss of Heterozygosity ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Mice ; Mice, Mutant Strains ; Oligonucleotide Array Sequence Analysis ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins p21(ras)/metabolism ; Real-Time Polymerase Chain Reaction ; ras Proteins/metabolism

المؤلفون: Godde NJ; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Sheridan JM; ACRF Stem Cells and Cancer Division, Walter and Eliza Hall Institute, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., Smith LK; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia., Pearson HB; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia., Britt KL; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Metastasis Research Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia., Galea RC; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia., Yates LL; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Visvader JE; ACRF Stem Cells and Cancer Division, Walter and Eliza Hall Institute, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., Humbert PO; Cell Cycle and Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia; Department of Molecular Biology and Biochemistry, The University of Melbourne, Parkville, Victoria, Australia.

المصدر: PLoS genetics [PLoS Genet] 2014 May 22; Vol. 10 (5), pp. e1004323. Date of Electronic Publication: 2014 May 22 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: MAP Kinase Signaling System*, Intracellular Signaling Peptides and Proteins/*physiology , Mammary Neoplasms, Experimental/*metabolism , Proto-Oncogene Proteins c-fos/*metabolism, Animals ; Cell Polarity ; Female ; Homeostasis ; Hyperplasia ; Mammary Glands, Animal/pathology ; Mammary Neoplasms, Experimental/pathology ; Mice ; Morphogenesis