المؤلفون: Cheng VC, Chan JF, Lau EH, Yam WC, Ho SK, Yau MC, Tse EY, Wong AC, Tai JW, Fan ST, Ho PL, Yuen KY

المصدر: Journal of Hospital Infection; Nov2011, Vol. 79 Issue 3, p206-210, 5p

المؤلفون: Chow N; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China., Long T; Centre for Virology, Vaccinology and Therapeutics Limited, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Microbiology and State Key Laboratory for Emerging Infectious Diseases, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China., Lee LK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China., Wong IT; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China., Lee AW; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China., Tam WY; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China., Wong HF; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China., Leung JS; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China., Chow FW; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China., Luk KS; Department of Pathology, Princess Margaret Hospital, Hong Kong Special Administrative Region, China., Ho AY; Department of Pathology, Princess Margaret Hospital, Hong Kong Special Administrative Region, China., Lam JY; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Hong Kong Special Administrative Region, China., Yau MC; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Hong Kong Special Administrative Region, China., Que TL; Department of Clinical Pathology, Tuen Mun Hospital, Hong Kong Special Administrative Region, China., Yip KT; Department of Clinical Pathology, Tuen Mun Hospital, Hong Kong Special Administrative Region, China., Chow VC; Department of Microbiology, Prince of Wales Hospital, Hong Kong Special Administrative Region, China., Wong RC; Department of Microbiology, Prince of Wales Hospital, Hong Kong Special Administrative Region, China., Mok BW; Centre for Virology, Vaccinology and Therapeutics Limited, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Microbiology and State Key Laboratory for Emerging Infectious Diseases, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China., Chen HL; Centre for Virology, Vaccinology and Therapeutics Limited, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Microbiology and State Key Laboratory for Emerging Infectious Diseases, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China., Siu GK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China.

المصدر: Viruses [Viruses] 2024 Jun 18; Vol. 16 (6). Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/epidemiology , COVID-19*/transmission , COVID-19*/virology , COVID-19*/prevention & control , SARS-CoV-2*/genetics , SARS-CoV-2*/classification , Quarantine* , Phylogeny* , Genome, Viral*, Humans ; Hong Kong/epidemiology ; Physical Distancing ; Male ; Female ; Adult ; Middle Aged ; Adolescent ; Child ; Aged ; Young Adult

SCR Organism: SARS-CoV-2 variants

المؤلفون: Lao HY; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China., Wong LL; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China., Hui Y; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China., Ng TT; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China., Chan CT; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China., Lo HW; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China., Yau MC; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong SAR, China., Leung EC; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong SAR, China., Wong RC; Department of Microbiology, Prince of Wales Hospital, Shatin, Hong Kong SAR, China., Ho AY; Department of Pathology, Princess Margaret Hospital, Kowloon, Hong Kong SAR, China., Yip KT; Department of Clinical Pathology, Tuen Mun Hospital, Tuen Mun, Hong Kong SAR, China., Lam JY; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong SAR, China., Chow VC; Department of Microbiology, Prince of Wales Hospital, Shatin, Hong Kong SAR, China., Luk KS; Department of Pathology, Princess Margaret Hospital, Kowloon, Hong Kong SAR, China., Que TL; Department of Clinical Pathology, Tuen Mun Hospital, Tuen Mun, Hong Kong SAR, China., Chow FWN; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China., Siu GK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.

المصدر: Frontiers in microbiology [Front Microbiol] 2024 Jan 09; Vol. 14, pp. 1324494. Date of Electronic Publication: 2024 Jan 09 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101548977 Publication Model: eCollection Cited Medium: Print ISSN: 1664-302X (Print) Linking ISSN: 1664302X NLM ISO Abbreviation: Front Microbiol Subsets: PubMed not MEDLINE

المؤلفون: Lao HY; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Ng TT; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Wong RY; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospitalgrid.417134.4, Hong Kong Special Administrative Region, China., Wong CS; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospitalgrid.417134.4, Hong Kong Special Administrative Region, China., Lee LK; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Wong DS; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Chan CT; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Jim SH; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Leung JS; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Lo HW; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Wong IT; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China., Yau MC; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospitalgrid.417134.4, Hong Kong Special Administrative Region, China., Lam JY; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospitalgrid.417134.4, Hong Kong Special Administrative Region, China., Wu AK; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospitalgrid.417134.4, Hong Kong Special Administrative Region, China., Siu GK; Department of Health Technology and Informatics, The Hong Kong Polytechnic Universitygrid.16890.36, Hong Kong Special Administrative Region, China.

المصدر: Journal of clinical microbiology [J Clin Microbiol] 2022 Jan 19; Vol. 60 (1), pp. e0176921. Date of Electronic Publication: 2021 Nov 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-660X (Electronic) Linking ISSN: 00951137 NLM ISO Abbreviation: J Clin Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: High-Throughput Nucleotide Sequencing*, Genes, rRNA ; Humans ; RNA, Ribosomal, 16S/chemistry ; RNA, Ribosomal, 16S/genetics ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods ; Workflow

المؤلفون: Chan CT; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Leung JS; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Lee LK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Lo HW; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Wong EY; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Wong DS; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Ng TT; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Lao HY; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Lu KK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Jim SH; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region., Yau MC; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Hong Kong Special Administrative Region., Lam JY; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Hong Kong Special Administrative Region., Ho AY; Department of Pathology, Princess Margaret Hospital, Hong Kong Special Administrative Region., Luk KS; Department of Pathology, Princess Margaret Hospital, Hong Kong Special Administrative Region., Yip KT; Department of Clinical Pathology, Tuen Mun Hospital, Hong Kong Special Administrative Region., Que TL; Department of Clinical Pathology, Tuen Mun Hospital, Hong Kong Special Administrative Region., To KK; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region., Siu GK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region. Electronic address: gilman.siu@polyu.edu.hk.

المصدر: Journal of virological methods [J Virol Methods] 2022 Jan; Vol. 299, pp. 114333. Date of Electronic Publication: 2021 Oct 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8005839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0984 (Electronic) Linking ISSN: 01660934 NLM ISO Abbreviation: J Virol Methods Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19* , SARS-CoV-2*, Humans ; Real-Time Polymerase Chain Reaction ; Whole Genome Sequencing

SCR Organism: SARS-CoV-2 variants

المؤلفون: Leung KS, Ng TT, Wu AK, Yau MC, Lao HY, Choi MP, Tam KK, Lee LK, Wong BK, Man Ho AY, Yip KT, Lung KC, Liu RW, Tso EY, Leung WS, Chan MC, Ng YY, Sin KM, Fung KS, Chau SK, To WK, Que TL, Shum DH, Yip SP, Yam WC, Siu GK

المصدر: Emerging infectious diseases [Emerg Infect Dis] 2021 Jan; Vol. 27 (1), pp. 196-204.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Disease Outbreaks*, COVID-19/*epidemiology , COVID-19/*virology, Adult ; Aged ; Aged, 80 and over ; COVID-19/transmission ; Cluster Analysis ; Disease Hotspot ; Evolution, Molecular ; Female ; Hong Kong/epidemiology ; Humans ; Male ; Middle Aged ; Mutation ; Phylogeny ; Phylogeography ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Viroporin Proteins/genetics ; Whole Genome Sequencing ; Young Adult

المؤلفون: Siu GK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, People's Republic of China., Lee LK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, People's Republic of China., Leung KS; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China., Leung JS; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, People's Republic of China., Ng TT; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, People's Republic of China., Chan CT; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, People's Republic of China., Tam KK; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China., Lao HY; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, People's Republic of China., Wu AK; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong Special Administrative Region, People's Republic of China., Yau MC; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong Special Administrative Region, People's Republic of China., Lai YW; Department of Clinical Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong Special Administrative Region, People's Republic of China., Fung KS; Department of Clinical Pathology, United Christian Hospital, Kwun Tong, Hong Kong Special Administrative Region, People's Republic of China., Chau SK; Department of Clinical Pathology, United Christian Hospital, Kwun Tong, Hong Kong Special Administrative Region, People's Republic of China., Wong BK; Department of Clinical Pathology, United Christian Hospital, Kwun Tong, Hong Kong Special Administrative Region, People's Republic of China., To WK; Department of Pathology, Princess Margaret Hospital, Kwai Chung, Hong Kong Special Administrative Region, People's Republic of China., Luk K; Department of Pathology, Princess Margaret Hospital, Kwai Chung, Hong Kong Special Administrative Region, People's Republic of China., Ho AY; Department of Pathology, Princess Margaret Hospital, Kwai Chung, Hong Kong Special Administrative Region, People's Republic of China., Que TL; Department of Clinical Pathology, Tuen Mun Hospital, Tuen Mun, Hong Kong Special Administrative Region, People's Republic of China., Yip KT; Department of Clinical Pathology, Tuen Mun Hospital, Tuen Mun, Hong Kong Special Administrative Region, People's Republic of China., Yam WC; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China., Shum DH; Faculty of Health and Social Science, The Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, People's Republic of China., Yip SP; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong Special Administrative Region, People's Republic of China.

المصدر: Emerging microbes & infections [Emerg Microbes Infect] 2020 Dec; Vol. 9 (1), pp. 2497-2500.

نوع المنشور: Letter

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/genetics, COVID-19/*epidemiology, Disease Outbreaks ; Hong Kong/epidemiology ; Humans

المؤلفون: Wang AW; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Yau MC; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Drug Design and Pharmacology (Center for Biopharmaceuticals), University of Copenhagen, Copenhagen, Denmark., Wang CK; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Sharmin N; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Yang RY; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Pless SA; Drug Design and Pharmacology (Center for Biopharmaceuticals), University of Copenhagen, Copenhagen, Denmark., Kurata HT; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada kurata@ualberta.ca.

المصدر: The Journal of general physiology [J Gen Physiol] 2018 Oct 01; Vol. 150 (10), pp. 1432-1443. Date of Electronic Publication: 2018 Aug 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE

مواضيع طبية MeSH: KCNQ Potassium Channels/*drug effects , Membrane Transport Modulators/*pharmacology, HEK293 Cells ; Humans ; KCNQ Potassium Channels/genetics ; Mutation

المؤلفون: Yau MC; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.; Department of Drug Design and Pharmacology (Center for Biopharmaceuticals), University of Copenhagen, Copenhagen, Denmark., Kim RY; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada., Wang CK; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada., Li J; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada., Ammar T; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada., Yang RY; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada., Pless SA; Department of Drug Design and Pharmacology (Center for Biopharmaceuticals), University of Copenhagen, Copenhagen, Denmark., Kurata HT; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada kurata@ualberta.ca.

المصدر: The Journal of general physiology [J Gen Physiol] 2018 Oct 01; Vol. 150 (10), pp. 1421-1431. Date of Electronic Publication: 2018 Aug 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Anticonvulsants/*pharmacology , Carbamates/*pharmacology , KCNQ3 Potassium Channel/*drug effects , Phenylenediamines/*pharmacology, Animals ; KCNQ3 Potassium Channel/genetics ; Mutation ; Xenopus laevis

المؤلفون: Kim RY; Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, 2176 Health Sciences Mall, Vancouver, British Columbia, Canada V6T 1Z3., Yau MC; Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, 2176 Health Sciences Mall, Vancouver, British Columbia, Canada V6T 1Z3., Galpin JD; Department of Molecular Physiology and Biophysics, University of Iowa, 285 Newton Road, Iowa City, Iowa 52242, USA., Seebohm G; Department of Cardiovascular Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1 (Gebäude D3), D-48149 Münster, Germany., Ahern CA; Department of Molecular Physiology and Biophysics, University of Iowa, 285 Newton Road, Iowa City, Iowa 52242, USA., Pless SA; Department of Drug Design and Pharmacology (Center for Biopharmaceuticals), University of Copenhagen, Jagtvej 160, DK-2100 Copenhagen, Denmark., Kurata HT; Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, 2176 Health Sciences Mall, Vancouver, British Columbia, Canada V6T 1Z3.

المصدر: Nature communications [Nat Commun] 2015 Sep 03; Vol. 6, pp. 8116. Date of Electronic Publication: 2015 Sep 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Anticonvulsants/*pharmacology , Carbamates/*pharmacology , KCNQ Potassium Channels/*drug effects , Neurons/*drug effects , Phenylenediamines/*pharmacology, Animals ; Anticonvulsants/metabolism ; Carbamates/metabolism ; Fluorine/metabolism ; Humans ; Hydrogen Bonding ; KCNQ Potassium Channels/genetics ; KCNQ Potassium Channels/metabolism ; KCNQ2 Potassium Channel/drug effects ; KCNQ2 Potassium Channel/genetics ; KCNQ2 Potassium Channel/metabolism ; KCNQ3 Potassium Channel/drug effects ; KCNQ3 Potassium Channel/genetics ; KCNQ3 Potassium Channel/metabolism ; Molecular Docking Simulation ; Mutagenesis, Site-Directed ; Neurons/metabolism ; Oocytes/drug effects ; Oocytes/metabolism ; Patch-Clamp Techniques ; Phenylenediamines/metabolism ; Tryptophan/metabolism ; Xenopus laevis