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المؤلفون: Chung H; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA. hchung@broadinstitute.org., Parkhurst CN; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA., Magee EM; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Phillips D; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA., Habibi E; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Chen F; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Yeung BZ; BioLegend Inc, San Diego, CA, USA., Waldman J; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Artis D; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Joan and Sanford I. Weill Department of Medicine, Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Regev A; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Genentech, South San Francisco, CA, USA. aviv.regev.sc@gmail.com.

المصدر: Nature methods [Nat Methods] 2021 Oct; Vol. 18 (10), pp. 1204-1212. Date of Electronic Publication: 2021 Oct 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE

مواضيع طبية MeSH: Computational Biology/*methods , Nuclear Proteins/*metabolism , Single-Cell Analysis/*methods, Animals ; Antibodies ; Brain/metabolism ; Gene Expression Regulation/physiology ; Genome-Wide Association Study ; Kainic Acid/toxicity ; Mice ; Nuclear Proteins/genetics ; RNA ; Reproducibility of Results ; Seizures/chemically induced ; Transcription Factor RelA/genetics ; Transcription Factor RelA/metabolism

المؤلفون: Mimitou EP; Technology Innovation Lab, New York Genome Center, New York, NY, USA., Lareau CA; Department of Pathology, Stanford University, Stanford, CA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology / Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Chen KY; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan., Zorzetto-Fernandes AL; BioLegend, Inc., San Diego, CA, USA., Hao Y; Center for Genomics and Systems Biology, New York University, New York, NY, USA.; New York Genome Center, New York, NY, USA., Takeshima Y; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Luo W; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology / Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Huang TS; BioLegend, Inc., San Diego, CA, USA., Yeung BZ; BioLegend, Inc., San Diego, CA, USA., Papalexi E; Center for Genomics and Systems Biology, New York University, New York, NY, USA.; New York Genome Center, New York, NY, USA., Thakore PI; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kibayashi T; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Wing JB; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Laboratory of Human Immunology (Single Cell Immunology), Immunology Frontier Research Center, Osaka University, Osaka, Japan., Hata M; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Satija R; Center for Genomics and Systems Biology, New York University, New York, NY, USA.; New York Genome Center, New York, NY, USA., Nazor KL; BioLegend, Inc., San Diego, CA, USA., Sakaguchi S; Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan., Ludwig LS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology / Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Sankaran VG; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology / Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; New York Genome Center, New York, NY, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Department of Biology and Koch Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA., Smibert P; Technology Innovation Lab, New York Genome Center, New York, NY, USA. smibertp@gmail.com.

المصدر: Nature biotechnology [Nat Biotechnol] 2021 Oct; Vol. 39 (10), pp. 1246-1258. Date of Electronic Publication: 2021 Jun 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: RNA-Seq/*methods , Single-Cell Analysis/*methods, Cell Differentiation ; Cell Lineage ; Chromatin/genetics ; Chromatin/metabolism ; DNA, Mitochondrial/genetics ; Epigenomics ; Gene Expression Profiling ; Gene Expression Regulation ; Hematopoiesis ; Humans ; Leukocytes, Mononuclear/cytology ; Leukocytes, Mononuclear/metabolism ; Proteins/genetics ; Proteins/metabolism ; T-Lymphocytes/cytology ; T-Lymphocytes/metabolism

المؤلفون: Hwang B; Institute for Human Genetics (IHG), University of California, San Francisco, San Francisco, CA, USA.; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA., Lee DS; Institute for Human Genetics (IHG), University of California, San Francisco, San Francisco, CA, USA.; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Tamaki W; Graduate Program in Pharmaceutical Sciences and Pharmacogenomics, University of California, San Francisco, San Francisco, CA, USA., Sun Y; Institute for Human Genetics (IHG), University of California, San Francisco, San Francisco, CA, USA.; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Ogorodnikov A; Institute for Human Genetics (IHG), University of California, San Francisco, San Francisco, CA, USA.; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Hartoularos GC; Institute for Human Genetics (IHG), University of California, San Francisco, San Francisco, CA, USA.; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Graduate Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, CA, USA., Winters A; Graduate Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, CA, USA., Yeung BZ; BioLegend Inc, San Diego, CA, USA., Nazor KL; BioLegend Inc, San Diego, CA, USA., Song YS; Computer Science Division, University of California, Berkeley, Berkeley, CA, USA.; Department of Statistics, University of California, Berkeley, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Chow ED; Center for Advanced Technology, Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Spitzer MH; Graduate Program in Biomedical Sciences, University of California, San Francisco, San Francisco, CA, USA.; Departments of Otolaryngology and Microbiology and Immunology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Ye CJ; Institute for Human Genetics (IHG), University of California, San Francisco, San Francisco, CA, USA. jimmie.ye@ucsf.edu.; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. jimmie.ye@ucsf.edu.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA. jimmie.ye@ucsf.edu.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA. jimmie.ye@ucsf.edu.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA. jimmie.ye@ucsf.edu.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. jimmie.ye@ucsf.edu.; Chan Zuckerberg Biohub, San Francisco, CA, USA. jimmie.ye@ucsf.edu.; J. David Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA. jimmie.ye@ucsf.edu.

المصدر: Nature methods [Nat Methods] 2021 Aug; Vol. 18 (8), pp. 903-911. Date of Electronic Publication: 2021 Aug 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome*, Flow Cytometry/*methods , High-Throughput Nucleotide Sequencing/*methods , Microfluidics/*methods , Sequence Analysis, RNA/*methods , Single-Cell Analysis/*methods, Case-Control Studies ; Gene Expression Profiling ; Humans

المؤلفون: Wang J; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA.; Institute of Quantitative Systems Pharmacology, Carlsbad, CA 92008, USA., Yeung BZ; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA.; Optimum Therapeutics LLC, Carlsbad, CA 92008, USA., Wientjes MG; Institute of Quantitative Systems Pharmacology, Carlsbad, CA 92008, USA.; Optimum Therapeutics LLC, Carlsbad, CA 92008, USA., Cui M; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA.; Optimum Therapeutics LLC, Carlsbad, CA 92008, USA., Peer CJ; Clinical Pharmacology Program, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Lu Z; Optimum Therapeutics LLC, Carlsbad, CA 92008, USA., Figg WD; Clinical Pharmacology Program, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Woo S; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA., Au JL; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA.; Institute of Quantitative Systems Pharmacology, Carlsbad, CA 92008, USA.; Optimum Therapeutics LLC, Carlsbad, CA 92008, USA.; College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.

المصدر: Pharmaceutics [Pharmaceutics] 2021 Jun 30; Vol. 13 (7). Date of Electronic Publication: 2021 Jun 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE

المؤلفون: Wu SZ; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia., Roden DL; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia., Al-Eryani G; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia., Bartonicek N; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia., Harvey K; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Cazet AS; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia., Chan CL; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, Sydney, Australia., Junankar S; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia., Hui MN; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Millar EA; NSW Health Pathology, Department of Anatomical Pathology, St George Hospital, Kogarah, NSW, Australia.; School of Medical Sciences, UNSW Sydney, Kensington, Australia.; Faculty of Medicine & Health Sciences, Sydney Western University, Campbelltown, NSW, Australia., Beretov J; NSW Health Pathology, Department of Anatomical Pathology, St George Hospital, Kogarah, NSW, Australia.; St George & Sutherland Clinical School, UNSW Sydney, Kensington, Australia., Horvath L; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; University of Sydney, Camperdown, NSW, Australia., Joshua AM; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Hospital, Darlinghurst, NSW, Australia., Stricker P; St Vincent's Hospital, Darlinghurst, NSW, Australia., Wilmott JS; Melanoma Institute Australia, The University of Sydney, Sydney, Australia.; The University of Sydney, Sydney, Australia., Quek C; Melanoma Institute Australia, The University of Sydney, Sydney, Australia.; The University of Sydney, Sydney, Australia., Long GV; Melanoma Institute Australia, The University of Sydney, Sydney, Australia.; The University of Sydney, Sydney, Australia.; Royal North Shore Hospital, St Leonards, NSW, Australia., Scolyer RA; Melanoma Institute Australia, The University of Sydney, Sydney, Australia.; The University of Sydney, Sydney, Australia.; Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, Australia., Yeung BZ; BioLegend, San Diego, CA, USA., Segara D; St Vincent's Hospital, Darlinghurst, NSW, Australia., Mak C; Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Warrier S; Department of Breast Surgery, Chris O'Brien Lifehouse, Camperdown, NSW, 2050, Australia.; Royal Prince Alfred Institute of Academic Surgery, Sydney University, Sydney, Australia., Powell JE; Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, Sydney, Australia.; UNSW Cellular Genomics Futures Institute, University of New South Wales, Sydney, Australia., O'Toole S; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia., Lim E; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia.; St Vincent's Hospital, Darlinghurst, NSW, Australia., Swarbrick A; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia. a.swarbrick@garvan.org.au.; St Vincent's Clinical School, Faculty of Medicine UNSW, Sydney, NSW, Australia. a.swarbrick@garvan.org.au.

المصدر: Genome medicine [Genome Med] 2021 May 10; Vol. 13 (1), pp. 81. Date of Electronic Publication: 2021 May 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE

مواضيع طبية MeSH: Biological Specimen Banks* , Cryopreservation*/methods , Cryopreservation*/standards , Genomics*/methods , Single-Cell Analysis*/methods, Neoplasms/*diagnosis, Biomarkers, Tumor ; Gene Expression Profiling/methods ; Gene Expression Regulation ; High-Throughput Nucleotide Sequencing ; Humans ; Immunophenotyping ; Neoplasms/etiology ; Organ Specificity/genetics ; Sequence Analysis, RNA/methods ; Signal Transduction

المؤلفون: Papalexi E; Center for Genomics and Systems Biology, New York University, New York, NY, USA.; New York Genome Center, New York, NY, USA., Mimitou EP; Technology Innovation Lab, New York Genome Center, New York, NY, USA., Butler AW; Center for Genomics and Systems Biology, New York University, New York, NY, USA.; New York Genome Center, New York, NY, USA., Foster S; New York Genome Center, New York, NY, USA., Bracken B; Center for Genomics and Systems Biology, New York University, New York, NY, USA.; New York Genome Center, New York, NY, USA., Mauck WM 3rd; New York Genome Center, New York, NY, USA., Wessels HH; New York Genome Center, New York, NY, USA., Hao Y; Center for Genomics and Systems Biology, New York University, New York, NY, USA.; New York Genome Center, New York, NY, USA., Yeung BZ; BioLegend Inc., San Diego, CA, USA., Smibert P; Technology Innovation Lab, New York Genome Center, New York, NY, USA., Satija R; Center for Genomics and Systems Biology, New York University, New York, NY, USA. rsatija@nygenome.org.; New York Genome Center, New York, NY, USA. rsatija@nygenome.org.

المصدر: Nature genetics [Nat Genet] 2021 Mar; Vol. 53 (3), pp. 322-331. Date of Electronic Publication: 2021 Mar 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: B7-H1 Antigen/*genetics , Immune Checkpoint Proteins/*physiology , Single-Cell Analysis/*methods, B7-2 Antigen/metabolism ; B7-H1 Antigen/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Clustered Regularly Interspaced Short Palindromic Repeats ; Cullin Proteins/genetics ; Cullin Proteins/metabolism ; Humans ; Kelch-Like ECH-Associated Protein 1/genetics ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Programmed Cell Death 1 Ligand 2 Protein/metabolism ; Receptors, Interferon/genetics ; Reproducibility of Results ; Signal-To-Noise Ratio ; THP-1 Cells ; Transcription Factors/genetics ; Transcription Factors/metabolism

المؤلفون: Arunachalam PS; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA., Charles TP; Department of Pathology and Laboratory Medicine, Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA, USA., Joag V; Department of Microbiology and Immunology, Center for Immunology, University of Minnesota, Minneapolis, MN, USA., Bollimpelli VS; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA., Scott MKD; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.; Center for Biomedical Informatics, Department of Medicine, Stanford University, Stanford, CA, USA., Wimmers F; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA., Burton SL; Department of Pathology and Laboratory Medicine, Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA, USA., Labranche CC; Department of Surgery, Duke University School of Medicine, Durham, NC, USA., Petitdemange C; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.; HIV Inflammation and Persistence Unit, Institut Pasteur, Paris, France., Gangadhara S; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA., Styles TM; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA., Quarnstrom CF; Department of Microbiology and Immunology, Center for Immunology, University of Minnesota, Minneapolis, MN, USA., Walter KA; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, USA., Ketas TJ; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY, USA., Legere T; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA., Jagadeesh Reddy PB; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.; Pfizer, Andover, MA, USA., Kasturi SP; Department of Pathology and Laboratory Medicine, Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA., Tsai A; BioLegend, San Diego, CA, USA., Yeung BZ; BioLegend, San Diego, CA, USA., Gupta S; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Tomai M; 3M Corporate Research and Materials Lab, Saint Paul, MN, USA., Vasilakos J; 3M Drug Delivery Systems, Saint Paul, MN, USA., Shaw GM; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kang CY; Department of Microbiology and Immunology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada., Moore JP; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY, USA., Subramaniam S; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Khatri P; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.; Center for Biomedical Informatics, Department of Medicine, Stanford University, Stanford, CA, USA., Montefiori D; Department of Surgery, Duke University School of Medicine, Durham, NC, USA., Kozlowski PA; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, USA., Derdeyn CA; Department of Pathology and Laboratory Medicine, Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA, USA. cderdey@emory.edu., Hunter E; Department of Pathology and Laboratory Medicine, Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA, USA. ehunte4@emory.edu., Masopust D; Department of Microbiology and Immunology, Center for Immunology, University of Minnesota, Minneapolis, MN, USA. masopust@umn.edu., Amara RR; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA. ramara@emory.edu., Pulendran B; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA. bpulend@stanford.edu.; Department of Pathology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA. bpulend@stanford.edu.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA. bpulend@stanford.edu.

المصدر: Nature medicine [Nat Med] 2020 Jun; Vol. 26 (6), pp. 932-940. Date of Electronic Publication: 2020 May 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Neutralizing/*drug effects , Antibodies, Viral/*drug effects , CD8-Positive T-Lymphocytes/*drug effects , Gene Products, gag/*genetics , Immunity, Cellular/*drug effects , SAIDS Vaccines/*pharmacology , Simian Acquired Immunodeficiency Syndrome/*prevention & control , Simian Immunodeficiency Virus/*immunology, Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; CD4-Positive T-Lymphocytes/drug effects ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Female ; Gene Products, gag/immunology ; Genetic Vectors ; Immunity, Cellular/immunology ; Immunity, Heterologous ; Immunogenicity, Vaccine ; Immunologic Memory/immunology ; Macaca mulatta ; Mucous Membrane ; Vagina

المؤلفون: Stoeckius M; Technology Innovation Lab, New York Genome Center, New York, NY, USA., Zheng S; NYU Center for Genomics and Systems Biology, New York Genome Center, New York, NY, USA., Houck-Loomis B; Technology Innovation Lab, New York Genome Center, New York, NY, USA., Hao S; Technology Innovation Lab, New York Genome Center, New York, NY, USA., Yeung BZ; BioLegend Inc., San Diego, CA, USA., Mauck WM 3rd; NYU Center for Genomics and Systems Biology, New York Genome Center, New York, NY, USA., Smibert P; Technology Innovation Lab, New York Genome Center, New York, NY, USA. psmibert@nygenome.org., Satija R; NYU Center for Genomics and Systems Biology, New York Genome Center, New York, NY, USA. rsatija@nygenome.org.

المصدر: Genome biology [Genome Biol] 2018 Dec 19; Vol. 19 (1), pp. 224. Date of Electronic Publication: 2018 Dec 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Study

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE

مواضيع طبية MeSH: Single-Cell Analysis/*methods , Staining and Labeling/*methods, 3T3 Cells ; Animals ; Genomics ; HEK293 Cells ; Humans ; Immunologic Techniques ; Mice ; Oligonucleotides

المؤلفون: Jaiprasart P; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, United States., Yeung BZ; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, United States; Optimum Therapeutics LLC, Carlsbad, CA 92008, United States., Lu Z; Optimum Therapeutics LLC, Carlsbad, CA 92008, United States; Institute of Quantitative Systems Pharmacology, Carlsbad, CA 92008, United States., Wientjes MG; Optimum Therapeutics LLC, Carlsbad, CA 92008, United States; Institute of Quantitative Systems Pharmacology, Carlsbad, CA 92008, United States., Cui M; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, United States; Optimum Therapeutics LLC, Carlsbad, CA 92008, United States; Institute of Quantitative Systems Pharmacology, Carlsbad, CA 92008, United States., Hsieh CM; College of Pharmacy, Taipei Medical University, Taipei, Taiwan, ROC., Woo S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, United States., Au JL; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, United States; Optimum Therapeutics LLC, Carlsbad, CA 92008, United States; Institute of Quantitative Systems Pharmacology, Carlsbad, CA 92008, United States; College of Pharmacy, Taipei Medical University, Taipei, Taiwan, ROC. Electronic address: jau@optimumtx.com.

المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2018 Jan 28; Vol. 270, pp. 101-113. Date of Electronic Publication: 2017 Dec 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

مواضيع طبية MeSH: Heparin/*administration & dosage , RNA, Small Interfering/*administration & dosage , Suramin/*administration & dosage , Survivin/*genetics, Biological Availability ; Gene Silencing ; HT29 Cells ; Humans ; Liposomes ; Transfection