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المؤلفون: Yuen Po-Wai, Deepak Sampath, Xiaolei Ma, Yongbo Liu, Anthony M. Giannetti, Janet Gunzner-Toste, Guiling Zhao, Xiaozhang Zheng, Weiru Wang, Thomas O'Brien, Nicholas J. Skelton, Yang Xiao, Leslie Wang, Rongbao Hua, Yen-Ching Ho, Yezhen Feng, Peter S. Dragovich, Youming Shen, Qiang Zhao, Chengcheng Wang, Eric Cheng, Brandon J. Bravo, Timm Baumeister, Lisa Crocker, Kenneth W. Bair, Bianca M. Liederer, Mark Zak, Hongxing Wu, Jason Oeh
المصدر: Journal of medicinal chemistry. 57(3)
مصطلحات موضوعية: Cyclopropanes, Models, Molecular, Stereochemistry, Protein Conformation, Pyridines, Nicotinamide phosphoribosyltransferase, Mice, Nude, Stereoisomerism, Antineoplastic Agents, Crystallography, X-Ray, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, Potency, Structure–activity relationship, Animals, Humans, Sulfones, Nicotinamide Phosphoribosyltransferase, IC50, chemistry.chemical_classification, Chemistry, Amides, Enzyme, Biochemistry, Cell culture, Molecular Medicine, Heterografts, Drug Screening Assays, Antitumor, Neoplasm Transplantation
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المؤلفون: Xiaorong Liang, Weiru Wang, Zhongguo Wang, Alexandre J. Buckmelter, Bianca M. Liederer, Maureen Caligiuri, Nicholas J. Skelton, Karl H. Clodfelter, Yang Xiao, Leslie Wang, Timm Baumeister, Thomas O'Brien, Peter S. Dragovich, Nikolai Kley, Mark Zak, Jiansheng Wu, Xiaozhang Zheng, Yezhen Feng, Angela Oh, Hongxing Wu, Guangxing Yang, Kenneth W. Bair, Geeta Sharma, Dominic J. Reynolds, Krista K. Bowman, Chase C. Smith, Jian Lin, Yuen Po-Wai, Jason Oeh, Hong Li, Jarrod Tremayne, Deepak Sampath, Paul Bauer, Yen-Ching Ho, Bingsong Han, Justin Ly
المصدر: Bioorganicmedicinal chemistry letters. 23(20)
مصطلحات موضوعية: Niacinamide, Pyridines, Clinical Biochemistry, Transplantation, Heterologous, Nicotinamide phosphoribosyltransferase, Carboxylic Acids, Pharmaceutical Science, Mice, Nude, Crystallography, X-Ray, Biochemistry, Retina, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, Structure–activity relationship, Animals, Humans, Sulfones, Enzyme Inhibitors, Nicotinamide Phosphoribosyltransferase, Molecular Biology, Cell Proliferation, chemistry.chemical_classification, Binding Sites, Cell growth, Organic Chemistry, Haplorhini, NAD, Amides, In vitro, Protein Structure, Tertiary, Rats, Enzyme, chemistry, Cell culture, Molecular Medicine, Cytokines, Pyrazoles, Female, NAD+ kinase, Half-Life
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