المؤلفون: Sarah J. Piper, Giuseppe Deganutti, Jessica Lu, Peishen Zhao, Yi-Lynn Liang, Yao Lu, Madeleine M. Fletcher, Mohammed Akhter Hossain, Arthur Christopoulos, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/f2ad6a82f21b446eaee66d37613979d6

المؤلفون: Ziva Vuckovic, Jinan Wang, Vi Pham, Jesse I Mobbs, Matthew J Belousoff, Apurba Bhattarai, Wessel AC Burger, Geoff Thompson, Mahmuda Yeasmin, Vindhya Nawaratne, Katie Leach, Emma T van der Westhuizen, Elham Khajehali, Yi-Lynn Liang, Alisa Glukhova, Denise Wootten, Craig W Lindsley, Andrew Tobin, Patrick Sexton, Radostin Danev, Celine Valant, Yinglong Miao, Arthur Christopoulos, David M Thal

المصدر: eLife, Vol 12 (2023)

مصطلحات موضوعية: allostery, drug discovery, molecular dynamics, molecular pharmacology, muscarinic acetylcholine receptors, structural biology, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/83477; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/7f71dbdee2334fc988c8a96b377f0938

المؤلفون: Giuseppe Deganutti, Yi-Lynn Liang, Xin Zhang, Maryam Khoshouei, Lachlan Clydesdale, Matthew J. Belousoff, Hari Venugopal, Tin T. Truong, Alisa Glukhova, Andrew N. Keller, Karen J. Gregory, Katie Leach, Arthur Christopoulos, Radostin Danev, Christopher A. Reynolds, Peishen Zhao, Patrick M. Sexton, Denise Wootten

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8f7e8894b23a4f8eb32f5d2c26ccefc6

المؤلفون: Radostin Danev, Matthew Belousoff, Yi-Lynn Liang, Xin Zhang, Fabian Eisenstein, Denise Wootten, Patrick M. Sexton

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/4b98c85f04bd463f9b6c1fcd192b0ef8

المؤلفون: Maoqing Dong, Giuseppe Deganutti, Sarah J. Piper, Yi-Lynn Liang, Maryam Khoshouei, Matthew J. Belousoff, Kaleeckal G. Harikumar, Christopher A. Reynolds, Alisa Glukhova, Sebastian G. B. Furness, Arthur Christopoulos, Radostin Danev, Denise Wootten, Patrick M. Sexton, Laurence J. Miller

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/35d3a9f45d2f49f5b92ff1e2f30c175a

المؤلفون: Xin Zhang, Matthew J. Belousoff, Yi-Lynn Liang, Radostin Danev, Patrick M. Sexton, Denise Wootten

المصدر: Cell Reports, Vol 36, Iss 2, Pp 109374- (2021)

مصطلحات موضوعية: glucagon-like peptide-1 receptor, GLP-1R, cryoelectron microscopy, GPCRs, GPCR dynamics, semaglutide, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124721007725; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/98a1b8a90b1f44578c7736121c0ec9c6

المؤلفون: Jesse I Mobbs, Vi Pham, Jinan Wang, Ziva Vuckovic, Matthew J Belousoff, Apurba Bhattarai, Wessel AC Burger, Geoff Thompson, Mahmuda Yeasmin, Vindhya Nawaratne, Katie Leach, Emma T van der Westhuizen, Elham Khajehali, Yi-Lynn Liang, Alisa Glukhova, Denise Wootten, Craig W Lindsley, Andrew Tobin, Patrick Sexton, Radostin Danev, Celine Valant, Yinglong Miao, Arthur Christopoulos, David M Thal

المصدر: eLife. 12

مصطلحات موضوعية: General Immunology and Microbiology, General Neuroscience, General Medicine, General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6a3f8c39932d4142cae5d5abc25a4480
https://doi.org/10.7554/elife.83477

المؤلفون: Zhaotong Cong, Yi-Lynn Liang, Qingtong Zhou, Sanaz Darbalaei, Fenghui Zhao, Wenbo Feng, Lihua Zhao, H. Eric Xu, Dehua Yang, Ming-Wei Wang

المصدر: Trends in Pharmacological Sciences. 43:321-334

مصطلحات موضوعية: Pharmacology, Protein Domains, Cryoelectron Microscopy, Humans, Crystallography, X-Ray, Ligands, Toxicology, Receptors, G-Protein-Coupled

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86e093f2f1e6aefe7e174f020bc75cc
https://doi.org/10.1016/j.tips.2022.01.002

المؤلفون: Lachlan Clydesdale, Hari Venugopal, Peishen Zhao, Patrick M. Sexton, Alisa Glukhova, Arthur Christopoulos, Christopher A. Reynolds, Yi Lynn Liang, Xin Zhang, Tin T. Truong, Andrew N. Keller, Maryam Khoshouei, Matthew J. Belousoff, Karen J. Gregory, Giuseppe Deganutti, Radostin Danev, Denise Wootten, Katie Leach

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Nature Communications

مصطلحات موضوعية: Protein Conformation, alpha-Helical, Gene Expression, General Physics and Astronomy, Peptide, Ligands, chemistry.chemical_compound, Receptor pharmacology, G protein-coupled receptors, Glucagon-Like Peptide 1, Cloning, Molecular, Receptor, chemistry.chemical_classification, Multidisciplinary, digestive, oral, and skin physiology, Recombinant Proteins, Transmembrane domain, Oxyntomodulin, Baculoviridae, hormones, hormone substitutes, and hormone antagonists, Protein Binding, Agonist, endocrine system, medicine.drug_class, G protein, Science, Genetic Vectors, Allosteric regulation, Molecular Dynamics Simulation, Glucagon-Like Peptide-1 Receptor, Article, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, Allosteric Regulation, Electron microscopy, medicine, Humans, Protein Interaction Domains and Motifs, Binding Sites, Cryoelectron Microscopy, Mutagenesis, General Chemistry, Kinetics, HEK293 Cells, chemistry, Mutation, Biophysics, Exenatide, Protein Conformation, beta-Strand

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5aa9dcac923a091ce55a4b69969de5
https://doaj.org/article/8f7e8894b23a4f8eb32f5d2c26ccefc6

المؤلفون: Vuckovic, Ziva, Jinan Wang, Vi Pham, Mobbs, Jesse I., Belousoff, Matthew J., Bhattarai, Apurba, Burger, Wessel A. C., Thompson, Geoff, Yeasmin, Mahmuda, Nawaratne, Vindhya, Leach, Katie, van der Westhuizen, Emma T., Khajehali, Elham, Yi-Lynn Liang, Glukhova, Alisa, Wootten, Denise, Lindsley, Craig W., Tobin, Andrew, Sexton, Patrick, Danev, Radostin

المصدر: eLife; 5/30/2023, p1-52, 52p