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المؤلفون: Anand RP; eGenesis, Cambridge, MA, USA., Layer JV; eGenesis, Cambridge, MA, USA., Heja D; eGenesis, Cambridge, MA, USA., Hirose T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Lassiter G; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Firl DJ; eGenesis, Cambridge, MA, USA.; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Paragas VB; eGenesis, Cambridge, MA, USA., Akkad A; eGenesis, Cambridge, MA, USA., Chhangawala S; eGenesis, Cambridge, MA, USA., Colvin RB; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Ernst RJ; eGenesis, Cambridge, MA, USA., Esch N; eGenesis, Cambridge, MA, USA., Getchell K; eGenesis, Cambridge, MA, USA., Griffin AK; eGenesis, Cambridge, MA, USA., Guo X; eGenesis, Cambridge, MA, USA., Hall KC; eGenesis, Cambridge, MA, USA., Hamilton P; eGenesis, Cambridge, MA, USA., Kalekar LA; eGenesis, Cambridge, MA, USA., Kan Y; eGenesis, Cambridge, MA, USA., Karadagi A; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Li F; eGenesis, Cambridge, MA, USA., Low SC; eGenesis, Cambridge, MA, USA., Matheson R; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Nehring C; eGenesis, Cambridge, MA, USA., Otsuka R; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Pandelakis M; eGenesis, Cambridge, MA, USA., Policastro RA; eGenesis, Cambridge, MA, USA., Pols R; eGenesis, Cambridge, MA, USA., Queiroz L; eGenesis, Cambridge, MA, USA., Rosales IA; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Serkin WT; eGenesis, Cambridge, MA, USA., Stiede K; eGenesis, Cambridge, MA, USA., Tomosugi T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Xue Y; eGenesis, Cambridge, MA, USA., Zentner GE; eGenesis, Cambridge, MA, USA., Angeles-Albores D; eGenesis, Cambridge, MA, USA., Chris Chao J; eGenesis, Cambridge, MA, USA., Crabtree JN; eGenesis, Cambridge, MA, USA., Harken S; eGenesis, Cambridge, MA, USA., Hinkle N; eGenesis, Cambridge, MA, USA., Lemos T; eGenesis, Cambridge, MA, USA., Li M; eGenesis, Cambridge, MA, USA., Pantano L; eGenesis, Cambridge, MA, USA., Stevens D; eGenesis, Cambridge, MA, USA., Subedar OD; eGenesis, Cambridge, MA, USA., Tan X; eGenesis, Cambridge, MA, USA., Yin S; eGenesis, Cambridge, MA, USA., Anwar IJ; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Aufhauser D; Department of Surgery, Division of Transplantation, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Capuano S; Wisconsin National Primate Research Center, Madison, WI, USA., Kaufman DB; Department of Surgery, Division of Transplantation, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Knechtle SJ; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Kwun J; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Shanmuganayagam D; Department of Animal and Dairy Science, University of Wisconsin, Madison, WI, USA., Markmann JF; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Church GM; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Wyss Institute of Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA., Curtis M; eGenesis, Cambridge, MA, USA., Kawai T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Youd ME; eGenesis, Cambridge, MA, USA. michele.youd@egenesisbio.com., Qin W; eGenesis, Cambridge, MA, USA. wenning.qin@egenesisbio.com.

المصدر: Nature [Nature] 2023 Oct; Vol. 622 (7982), pp. 393-401. Date of Electronic Publication: 2023 Oct 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Graft Rejection*/immunology , Graft Rejection*/prevention & control , Kidney Transplantation*/methods , Macaca fascicularis* , Swine*/genetics , Transplantation, Heterologous*/methods, Animals ; Humans ; Animals, Genetically Modified ; Endothelial Cells/immunology ; Endothelial Cells/metabolism ; Polysaccharides/deficiency ; Transgenes/genetics

المؤلفون: Petitpas K; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Habibabady Z; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Ritchie V; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Connolly MR; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Burdorf L; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Qin W; eGenesis Inc., Cambridge, Massachusetts, USA., Kan Y; eGenesis Inc., Cambridge, Massachusetts, USA., Layer JV; eGenesis Inc., Cambridge, Massachusetts, USA., Crabtree JN; eGenesis Inc., Cambridge, Massachusetts, USA., Youd ME; eGenesis Inc., Cambridge, Massachusetts, USA., Westlin WF; eGenesis Inc., Cambridge, Massachusetts, USA., Magnani DM; MassBiologics of UMMS, Boston, Massachusetts, USA., Pierson RN 3rd; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA., Azimzadeh AM; MGH, Center for Transplantation Sciences, Boston, Massachusetts, USA.

المصدر: Xenotransplantation [Xenotransplantation] 2022 Nov; Vol. 29 (6), pp. e12780. Date of Electronic Publication: 2022 Sep 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Munksgaard International Publishers Country of Publication: Denmark NLM ID: 9438793 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-3089 (Electronic) Linking ISSN: 0908665X NLM ISO Abbreviation: Xenotransplantation Subsets: MEDLINE

مواضيع طبية MeSH: Sialic Acid Binding Ig-like Lectin 1*/genetics , N-Acetylneuraminic Acid*/metabolism, Humans ; Swine ; Animals ; Transplantation, Heterologous/methods ; Macrophages ; Erythrocytes/metabolism

المؤلفون: Ma D; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Hirose T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Lassiter G; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sasaki H; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Rosales I; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Coe TM; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Rickert CG; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Matheson R; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Colvin RB; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Qin W; eGenesis Inc., Cambridge, Massachusetts, USA., Kan Y; eGenesis Inc., Cambridge, Massachusetts, USA., Layer JV; eGenesis Inc., Cambridge, Massachusetts, USA., Paragas VB; eGenesis Inc., Cambridge, Massachusetts, USA., Stiede K; eGenesis Inc., Cambridge, Massachusetts, USA., Hall KC; eGenesis Inc., Cambridge, Massachusetts, USA., Youd ME; eGenesis Inc., Cambridge, Massachusetts, USA., Queiroz LM; eGenesis Inc., Cambridge, Massachusetts, USA., Westlin WF; eGenesis Inc., Cambridge, Massachusetts, USA., Curtis M; eGenesis Inc., Cambridge, Massachusetts, USA., Yang L; eGenesis Inc., Cambridge, Massachusetts, USA., Markmann JF; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; eGenesis Inc., Cambridge, Massachusetts, USA., Kawai T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

المصدر: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2022 Jan; Vol. 22 (1), pp. 46-57. Date of Electronic Publication: 2021 Aug 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100968638 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-6143 (Electronic) Linking ISSN: 16006135 NLM ISO Abbreviation: Am J Transplant Subsets: MEDLINE

مواضيع طبية MeSH: Kidney Transplantation*, Animals ; Animals, Genetically Modified ; Graft Rejection/genetics ; Humans ; Macaca fascicularis ; Swine ; Transplantation, Heterologous

المؤلفون: Yue Y; Qihan Bio Inc, Hangzhou, China., Xu W; Qihan Bio Inc, Hangzhou, China., Kan Y; eGenesis Inc, Cambridge, MA, USA., Zhao HY; Key Laboratory of Animal Gene Editing and Animal Cloning in Yunnan Province, Yunnan Agricultural University, Kunming, China., Zhou Y; Qihan Bio Inc, Hangzhou, China., Song X; Qihan Bio Inc, Hangzhou, China., Wu J; Qihan Bio Inc, Hangzhou, China., Xiong J; Qihan Bio Inc, Hangzhou, China., Goswami D; eGenesis Inc, Cambridge, MA, USA., Yang M; Qihan Bio Inc, Hangzhou, China., Lamriben L; eGenesis Inc, Cambridge, MA, USA., Xu M; Qihan Bio Inc, Hangzhou, China., Zhang Q; Qihan Bio Inc, Hangzhou, China., Luo Y; Qihan Bio Inc, Hangzhou, China., Guo J; Key Laboratory of Animal Gene Editing and Animal Cloning in Yunnan Province, Yunnan Agricultural University, Kunming, China., Mao S; Key Laboratory of Animal Gene Editing and Animal Cloning in Yunnan Province, Yunnan Agricultural University, Kunming, China., Jiao D; Key Laboratory of Animal Gene Editing and Animal Cloning in Yunnan Province, Yunnan Agricultural University, Kunming, China., Nguyen TD; Key Laboratory of Animal Gene Editing and Animal Cloning in Yunnan Province, Yunnan Agricultural University, Kunming, China., Li Z; Key Laboratory of Animal Gene Editing and Animal Cloning in Yunnan Province, Yunnan Agricultural University, Kunming, China., Layer JV; eGenesis Inc, Cambridge, MA, USA., Li M; eGenesis Inc, Cambridge, MA, USA., Paragas V; eGenesis Inc, Cambridge, MA, USA., Youd ME; eGenesis Inc, Cambridge, MA, USA., Sun Z; Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Ding Y; Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Wang W; Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Dou H; Qihan Bio Inc, Hangzhou, China., Song L; Qihan Bio Inc, Hangzhou, China., Wang X; Qihan Bio Inc, Hangzhou, China., Le L; Qihan Bio Inc, Hangzhou, China., Fang X; Qihan Bio Inc, Hangzhou, China., George H; eGenesis Inc, Cambridge, MA, USA., Anand R; eGenesis Inc, Cambridge, MA, USA., Wang SY; eGenesis Inc, Cambridge, MA, USA., Westlin WF; eGenesis Inc, Cambridge, MA, USA., Güell M; Department of Experimental and Health Sciences, Pompeu Fabra University, Barcelona, Spain., Markmann J; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Qin W; eGenesis Inc, Cambridge, MA, USA., Gao Y; Qihan Bio Inc, Hangzhou, China., Wei HJ; Key Laboratory of Animal Gene Editing and Animal Cloning in Yunnan Province, Yunnan Agricultural University, Kunming, China., Church GM; Department of Genetics, Harvard Medical School, Boston, MA, USA., Yang L; Qihan Bio Inc, Hangzhou, China. luhan.yang@qihanbio.com.

المصدر: Nature biomedical engineering [Nat Biomed Eng] 2021 Feb; Vol. 5 (2), pp. 134-143. Date of Electronic Publication: 2020 Sep 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-846X (Electronic) Linking ISSN: 2157846X NLM ISO Abbreviation: Nat Biomed Eng Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems* , Transplantation, Heterologous*, Genetic Engineering/*methods , Germ Cells/*metabolism , Sus scrofa/*genetics , Sus scrofa/*virology, Animals ; CRISPR-Associated Protein 9/genetics ; Cells, Cultured ; Galactosyltransferases/genetics ; Gene Knockout Techniques ; Mixed Function Oxygenases/genetics ; N-Acetylgalactosaminyltransferases/genetics ; Sus scrofa/immunology

المؤلفون: Richmond JM; Department of Medicine, Division of Dermatology, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Masterjohn E; Protein Production and Biology, Sanofi-Genzyme, Framingham, Massachusetts, USA., Chu R; Protein Production and Biology, Sanofi-Genzyme, Framingham, Massachusetts, USA., Tedstone J; Immunology and Inflammation Research, Sanofi-Genzyme, Framingham, Massachusetts, USA., Youd ME; Immunology and Inflammation Research, Sanofi-Genzyme, Framingham, Massachusetts, USA., Harris JE; Department of Medicine, Division of Dermatology, University of Massachusetts Medical School, Worcester, Massachusetts, USA. Electronic address: john.harris@umassmed.edu.

المصدر: The Journal of investigative dermatology [J Invest Dermatol] 2017 Apr; Vol. 137 (4), pp. 982-985. Date of Electronic Publication: 2017 Jan 23.

نوع المنشور: Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1747 (Electronic) Linking ISSN: 0022202X NLM ISO Abbreviation: J Invest Dermatol Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies/*therapeutic use , Receptors, CXCR3/*antagonists & inhibitors , Vitiligo/*drug therapy, Animals ; CD8-Positive T-Lymphocytes/immunology ; Chemokine CXCL10/physiology ; Mice ; Mice, Inbred C57BL ; Receptors, CXCR3/physiology

المؤلفون: Richmond JM; University of Massachusetts Medical School, Department of Medicine, Division of Dermatology, Worcester, Massachusetts, USA., Bangari DS; Sanofi-Genzyme, Framingham, Massachusetts, USA., Essien KI; University of Massachusetts Medical School, Department of Medicine, Division of Dermatology, Worcester, Massachusetts, USA., Currimbhoy SD; University of Texas Southwestern Medical Center, Dallas, Texas, USA., Groom JR; The Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Department of Medical Biology 1G Royal Parade, Victoria, Australia., Pandya AG; University of Texas Southwestern Medical Center, Dallas, Texas, USA., Youd ME; Sanofi-Genzyme, Framingham, Massachusetts, USA., Luster AD; Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Harris JE; University of Massachusetts Medical School, Department of Medicine, Division of Dermatology, Worcester, Massachusetts, USA. Electronic address: john.harris@umassmed.edu.

المصدر: The Journal of investigative dermatology [J Invest Dermatol] 2017 Feb; Vol. 137 (2), pp. 350-358. Date of Electronic Publication: 2016 Sep 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1747 (Electronic) Linking ISSN: 0022202X NLM ISO Abbreviation: J Invest Dermatol Subsets: MEDLINE

مواضيع طبية MeSH: Chemokines/*physiology , Epidermis/*immunology , T-Lymphocytes/*physiology , Vitiligo/*immunology, Animals ; Biomarkers/analysis ; Chemokine CXCL10/analysis ; Chemokine CXCL10/physiology ; Chemokine CXCL9/analysis ; Chemokine CXCL9/physiology ; Humans ; Interferon-gamma/physiology ; Keratinocytes/immunology ; Mice ; Mice, Inbred C57BL ; Severity of Illness Index ; Vitiligo/drug therapy

المؤلفون: Kaplan JM; Genzyme Corporation, 49 New York Avenue, Framingham, MA 01701, USA. johanne.kaplan@genzyme.com, Youd ME, Lodie TA

المصدر: Current stem cell research & therapy [Curr Stem Cell Res Ther] 2011 Dec; Vol. 6 (4), pp. 297-316.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101272517 Publication Model: Print Cited Medium: Internet ISSN: 2212-3946 (Electronic) Linking ISSN: 1574888X NLM ISO Abbreviation: Curr Stem Cell Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Cellular* , Stem Cell Transplantation*, Mesenchymal Stem Cells/*immunology, Animals ; Antigen-Presenting Cells/immunology ; Autoimmune Diseases/therapy ; Cell Differentiation ; Clinical Trials as Topic ; Cytokines/immunology ; Disease Models, Animal ; Humans ; Immunity, Humoral ; Killer Cells, Natural/immunology ; Mesenchymal Stem Cells/cytology ; Mice