يعرض 1 - 10 نتائج من 27 نتيجة بحث عن '"Youssef El-Ahmad"', وقت الاستعلام: 0.94s تنقيح النتائج
  1. 1
    Supplementary RNAseq Data from SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models

    المؤلفون: Monsif Bouaboula, Laurent Debussche, Carlos Garcia-Echeverria, Hong Cheng, Bruno Filoche-Rommé, Gary McCort, Fabienne Thompson, Victor Certal, Michel Tabart, Frank Halley, Youssef El-Ahmad, Laurent Schio, Pierre-Yves Abecassis, Dinesh S. Bangari, Anne Caron, Laurent Besret, Joon Sang Lee, Jack Pollard, Hui Cao, Rosalia Arrebola, Albane Courjaud, Dietmar Hoffmann, Mikhail N. Levit, Jessica McManus, Andrew T. Hebert, Zhuyan Guo, Malvika Koundinya, Fangxian Sun, Jane Cheng, Maysoun Shomali

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10eddd92e318753beaf14063960214f
    https://doi.org/10.1158/1535-7163.22520766

    أضف إلى المفضلة
  2. 2
    Data from SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models

    المؤلفون: Monsif Bouaboula, Laurent Debussche, Carlos Garcia-Echeverria, Hong Cheng, Bruno Filoche-Rommé, Gary McCort, Fabienne Thompson, Victor Certal, Michel Tabart, Frank Halley, Youssef El-Ahmad, Laurent Schio, Pierre-Yves Abecassis, Dinesh S. Bangari, Anne Caron, Laurent Besret, Joon Sang Lee, Jack Pollard, Hui Cao, Rosalia Arrebola, Albane Courjaud, Dietmar Hoffmann, Mikhail N. Levit, Jessica McManus, Andrew T. Hebert, Zhuyan Guo, Malvika Koundinya, Fangxian Sun, Jane Cheng, Maysoun Shomali

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b86af78b2f4b0ea0bc017ba86b84056
    https://doi.org/10.1158/1535-7163.c.6542763

    أضف إلى المفضلة
  3. 3
    Supplementary Data from SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models

    المؤلفون: Monsif Bouaboula, Laurent Debussche, Carlos Garcia-Echeverria, Hong Cheng, Bruno Filoche-Rommé, Gary McCort, Fabienne Thompson, Victor Certal, Michel Tabart, Frank Halley, Youssef El-Ahmad, Laurent Schio, Pierre-Yves Abecassis, Dinesh S. Bangari, Anne Caron, Laurent Besret, Joon Sang Lee, Jack Pollard, Hui Cao, Rosalia Arrebola, Albane Courjaud, Dietmar Hoffmann, Mikhail N. Levit, Jessica McManus, Andrew T. Hebert, Zhuyan Guo, Malvika Koundinya, Fangxian Sun, Jane Cheng, Maysoun Shomali

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3813137435b6e50ede54df16b76c6dfc
    https://doi.org/10.1158/1535-7163.22520769.v1

    أضف إلى المفضلة
  4. 4
    Discovery and Chemical Development of Amcenestrant: An Oral Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer

    المؤلفون: Youssef El-Ahmad, Veronique Croq, Christian Wehrey, Maysoun Shomali, Laurent Schio

    المصدر: ACS Symposium Series ISBN: 9780841297333

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9d926dc0916fc9b48c711bcdc18b28b0
    https://doi.org/10.1021/bk-2022-1423.ch007

    أضف إلى المفضلة
  5. 5
    Scalable Synthesis of (R,R)-N,N-Dibenzyl-2-fluorocyclohexan-1-amine with CsF under Hydrogen Bonding Phase-Transfer Catalysis

    المؤلفون: Anna Chiara Vicini, Diké-Michel Alozie, Philippe Courtes, Giulia Roagna, Catherine Aubert, Victor Certal, Youssef El-Ahmad, Sébastien Roy, Véronique Gouverneur

    المصدر: Organic Process Research & Development. 25:2730-2737

    مصطلحات موضوعية: 010405 organic chemistry, Organic Chemistry, Physical and Theoretical Chemistry, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de6753242f6c96ee0b91554123e58be
    https://doi.org/10.1021/acs.oprd.1c00312

    Find this issue from the American Chemical Society
    أضف إلى المفضلة
  6. 6
    Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer

    المؤلفون: Chrystelle Girardet, Magali Mathieu, François Vallée, Jacques Le-Roux, Fangxian Sun, Laurence Fabien, Corinne Terrier, Celine Ginesty, Bruno Filoche-Romme, Florence Gruss-Leleu, Maysoun Shomali, Monsif Bouaboula, Sylvie Beccari, Pascal Desmazeau, Gilles Lebourg, Tsiala Benard, Victor Certal, Pascale Vicat, Andrew Hebert, Carlos Garcia-Echeverria, Laurent Schio, Youssef El-Ahmad, Gary Mccort, Claire Muller, Maurice Brollo, Mikhail Levit, Luc Bertin, Hong Cheng, Véronique Loyau, Valerie Steier, Fabienne Thompson, Audrey Louboutin, Fabienne Pilorge, Alexey Rak, Frank Halley, Patrick Richepin, Christelle Perrault, Pierre-Yves Abecassis, Michel Tabart, Albane Courjaud

    المصدر: Journal of Medicinal Chemistry. 63:512-528

    مصطلحات موضوعية: 0303 health sciences, biology, Fulvestrant, Chemistry, Estrogen receptor, medicine.disease, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Breast cancer, Hormone receptor, Drug Discovery, biology.protein, medicine, Cancer research, Molecular Medicine, Aromatase, Receptor, Estrogen receptor alpha, Tamoxifen, 030304 developmental biology, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eb6b8e31876cd3009f301f509589bd98
    https://doi.org/10.1021/acs.jmedchem.9b01293

    Find this issue from the American Chemical Society
    أضف إلى المفضلة
  7. 7
    Abstract P4-02-08: Amcenestrant in combination with CDK4/6 inhibitor palbociclib demonstrates synergistic anti-tumor activity in ER+ endocrine-resistant breast cancer xenograft models

    المؤلفون: Maysoun Shomali, Zhuyan Guo, Jane Cheng, Amy Sullivan, Youssef El-Ahmad, Fangxian Sun, Sukhvinder Sidhu, Joon Sang Lee, Hui Cai, Jack Pollard, Laurent Debussche, Chris Soria, Monsif Bouaboula

    المصدر: Cancer Research. 82:P4-02

    مصطلحات موضوعية: Cancer Research, Oncology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a2505d83d780d649e8ce322533ce5307
    https://doi.org/10.1158/1538-7445.sabcs21-p4-02-08

    أضف إلى المفضلة
  8. 8
    Optimization and Gram-Scale Preparation of S -Trifluoromethyl Sulfoximines and Sulfilimino Iminiums, Powerful Reagents for the Late Stage Introduction of the CF 3 Group

    المؤلفون: Youssef El-Ahmad, Laurence Fabien, Luc Bertin, Guillaume Dagousset, Christian Poma, Elsa Anselmi, Bruno Salgues, Victor Certal, Philippe Courtes, Anne-Laure Barthelemy, Emmanuel Magnier

    المساهمون: Centre National de la Recherche Scientifique (CNRS), Institut Lavoisier de Versailles (ILV), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Organic Process Research and Development
    Organic Process Research and Development, American Chemical Society, 2020, 24 (5), pp.704-712. ⟨10.1021/acs.oprd.9b00403⟩

    مصطلحات موضوعية: Trifluoromethyl, Scale (ratio), 010405 organic chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Organic Chemistry, Late stage, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, 3. Good health, chemistry.chemical_compound, chemistry, Group (periodic table), Reagent, Organic chemistry, Physical and Theoretical Chemistry, ComputingMilieux_MISCELLANEOUS, Gram

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0b114c3d1037db332e87d0c0a92fed
    https://hal.archives-ouvertes.fr/hal-02992781

    Find this issue from the American Chemical Society
    أضف إلى المفضلة
  9. 9
    SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models

    المؤلفون: Youssef El-Ahmad, Hong Cheng, Fabienne Thompson, Monsif Bouaboula, Jack Pollard, Gary Mccort, Andrew Hebert, Carlos Garcia-Echeverria, Michel Tabart, Fangxian Sun, Laurent Schio, Joon Sang Lee, Dinesh S. Bangari, Jane Cheng, Laurent Besret, Hui Cao, Dietmar Hoffmann, Maysoun Shomali, Rosalia Arrebola, Zhuyan Guo, Anne Caron, Laurent Debussche, Frank Halley, Bruno Filoche-Romme, Albane Courjaud, Mikhail Levit, Malvika Koundinya, Jessica McManus, Victor Certal, Pierre-Yves Abecassis

    المصدر: Molecular cancer therapeutics. 20(2)

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.drug_class, Estrogen receptor, Breast Neoplasms, 03 medical and health sciences, Mice, 0302 clinical medicine, Breast cancer, In vivo, medicine, Animals, Humans, Receptor, Fulvestrant, business.industry, Wild type, medicine.disease, Disease Models, Animal, 030104 developmental biology, Oncology, Receptors, Estrogen, Estrogen, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, Female, business, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a793f8b26300e48375f0775740c17d0
    https://pubmed.ncbi.nlm.nih.gov/33310762

    أضف إلى المفضلة
  10. 10
    كتاب إلكتروني
    Complete Accounts of Integrated Drug Discovery and Development: Recent Examples From the Pharmaceutical Industry. Volume 4

    المؤلفون: Jaan A. Pesti, Ahmed F. Abdel-Magid, Rajappa Vaidyanathan, Matthew Maddess, John McIntosh, Wonsuk Chang, Trung Cao, Natalia Dyatkina, Sébastien Lemaire, Marija Prhavc, Simon Wagschal, Jun Liang, Jie Xu, Scott H. Watterson, Steven R. Wisniewski, Seb Caille, Brian S. Lucas, T. G. Murali Dhar, William P. Gallagher, John R. Coombs, F. González-Bobes, Youssef El-Ahmad, Veronique Croq, Christian Wehrey, Maysoun Shomali, Laurent Schio, Christian Moessner, Fabienne Hoffmann-Emery, Jean-Michel Adam, Serena Fantasia, Daniel Fishlock, Roland Meier, Georg Wuitschik, Hasane Ratni, John Studley

    نوع المادة: eBook.

    تصنيفات: SCIENCE / Chemistry / Organic, SCIENCE / Chemistry / Industrial & Technical

    أضف إلى المفضلة
أدوات البحث: أحصل على تغذية RSS – أرسل هذا البحث بالبريد الإلكتروني – حفظ البحث – جدول التنبيهات: لا شيء