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1
المؤلفون: Jacek Kwiatkowski, Nithya Baburajendran, Anders Poulsen, Boping Liu, Doris Hui Ying Tee, Yun Xuan Wong, Zhi Ying Poh, Esther HQ Ong, Nurul Dinie, Joseph Cherian, Anna Elisabet Jansson, Jeffrey Hill, Thomas H. Keller, Alvin W. Hung
المصدر: ACS Medicinal Chemistry Letters. 10:318-323
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry
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2
المؤلفون: John I. Manchester, Vishal Pendharkar, Thomas H. Keller, Yvonne Tan, Shi Hua Ang, Si Si Liew, Sum Wai Eldwin Tan, Zhi Ying Poh, Yin Sze Joyner Wong, Kanda Sangthongpitag, Fui Mee Ng, Weiling Wang, Jeffrey Hill, Joseph Cherian, Yun Xuan Wong, Gregory S. Basarab, Soo Yei Ho, Anders Poulsen
المصدر: European Journal of Medicinal Chemistry. 157:610-621
مصطلحات موضوعية: DNA Topoisomerase IV, 0301 basic medicine, Gram-negative bacteria, Topoisomerase Inhibitors, 030106 microbiology, Microbial Sensitivity Tests, DNA gyrase, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Escherichia coli, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Organic Chemistry, General Medicine, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Anti-Bacterial Agents, Streptococcus pneumoniae, 030104 developmental biology, Membrane, Biochemistry, DNA Gyrase, Permeability (electromagnetism), Efflux, Bacteria
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3
المؤلفون: Jia Yi Fong, Gang Wang, Xue Guo, Joma Joy, Shu Ting Tan, Yun Xuan Wong, Qian Wen Tan, Subramanyam Vankadara, Yi Yang See, Boping Liu, C. S. Brian Chia, Li Hong Tan, Ratna Karuna
المصدر: Bioorganic & Medicinal Chemistry Letters
مصطلحات موضوعية: 2019-20 coronavirus outbreak, Research groups, Coronavirus disease 2019 (COVID-19), Peptidomimetic, Head to head, medicine.medical_treatment, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Clinical Biochemistry, Drug target, Pharmaceutical Science, Pharmacology, Cysteine Proteinase Inhibitors, Cysteine protease inhibitors, Biochemistry, Antiviral Agents, Article, Inhibitory Concentration 50, Drug Discovery, medicine, Fluorescence Resonance Energy Transfer, Molecular Biology, Coronavirus 3C Proteases, ComputingMethodologies_COMPUTERGRAPHICS, Enzyme Assays, Protease, Chemistry, SARS-CoV-2, Organic Chemistry, 3CLpro, Molecular Medicine, Peptidomimetics, Peptidomimetic inhibitors, Mpro, Protein Binding
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4
المؤلفون: Yang Chen, Yun Xuan Wong, Tram T. Dang, Dang T. Nguyen, Ganesh R. Kokil
المساهمون: School of Chemical and Biomedical Engineering, School of Chemistry, Chemical Engineering and Biotechnology
مصطلحات موضوعية: Cell Survival, 0206 medical engineering, Cell, Biomedical Engineering, Geometry, Capsules, 02 engineering and technology, Biochemistry, Biomaterials, Islets of Langerhans, Cell Line, Tumor, Islet-Like Microtissue, medicine, Animals, Viability assay, Molecular Biology, geography, Cellular Viability, geography.geographical_feature_category, Toroid, Chemistry, Microtissue Geometry, Diabetes, Spheroid, Rat Insulinoma, Chemical engineering [Engineering], Hydrogels, General Medicine, Cells, Immobilized, 021001 nanoscience & nanotechnology, Islet, 020601 biomedical engineering, Rats, Transplantation, medicine.anatomical_structure, Diabetes Mellitus, Type 1, Self-healing hydrogels, Encapsulation, 0210 nano-technology, Biotechnology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21997349f5199d4d78ebb01e6e49fec4
https://hdl.handle.net/10356/161857 -
5
المؤلفون: Vithya Manoharan, Yun Xuan Wong, Esther H. Q. Ong, Kassoum Nacro, John Liang Kuan Wee, Zekui Perlyn Kwek, Sharon Xiaodai Lim, Jeffrey Hill, Yun Shan Chew, Zhi Ying Poh, S. Tiong Ong, Thomas H. Keller, Li Jun Ding, Joma Joy, Vishal Pendharkar, Samantha Guo, Kanda Sangthongpitag, Anders Poulsen, Hai Yan Yang, May Ann Lee, Boping Liu, Meng Ling Choong, Duraiswamy Athisayamani Jeyaraj, Joseph Cherian, Melvyn Ho
المصدر: Journal of Medicinal Chemistry. 59:3063-3078
مصطلحات موضوعية: 0301 basic medicine, Myeloid, Fusion Proteins, bcr-abl, Administration, Oral, Biological Availability, Antineoplastic Agents, Chemistry Techniques, Synthetic, Mice, SCID, Protein Serine-Threonine Kinases, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, hemic and lymphatic diseases, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Molecular Targeted Therapy, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, biology, Chemistry, Kinase, EIF4E, Intracellular Signaling Peptides and Proteins, Myeloid leukemia, medicine.disease, Xenograft Model Antitumor Assays, Leukemia, Eukaryotic Initiation Factor-4E, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mitogen-activated protein kinase, Immunology, Cancer research, biology.protein, Molecular Medicine, Female, Stem cell
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6
المؤلفون: Sugunavathi Sepramaniam, Boping Liu, Nur Huda Binte Ahmad, Vishal Pendharkar, Esther Hq Ong, Jacek Kwiatkowski, Eldwin Sum Wai Tan, Anders Poulsen, Guo-Ying Chen, Jeffrey Hill, Doris Hui Ying Tee, Thomas H. Keller, Joseph Cherian, Kanda Sangthongpitag, Soo Yei Ho, Yun Xuan Wong, Nurul Dinie, Alvin W. Hung, Zhi Ying Poh, Shi Hua Ang, May Ann Lee
المصدر: Journal of medicinal chemistry. 61(10)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Carcinoma, Hepatocellular, Molecular model, Protein Conformation, Fragment-based lead discovery, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Tumor Cells, Cultured, Humans, Protein Kinase Inhibitors, Protein kinase C, Protein Kinase C, Cell Proliferation, Molecular Structure, Chemistry, Kinase, Liver Neoplasms, Cancer, Protein kinase C iota, medicine.disease, Isoenzymes, 030104 developmental biology, Biochemistry, 030220 oncology & carcinogenesis, Molecular Medicine
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7
المؤلفون: CongBao Kang, Thomas H. Keller, Yun Xuan Wong, Michelle Yueqi Lee, Yan Li, Hui Qi Ng, Zhi Ying Poh, Alvin W. Hung, Jeffrey Hill, Boping Liu, Ying Lei Wong, Fui Mee Ng, Siew Wen Then, Joseph Cherian
المصدر: Biochemical and biophysical research communications. 467(4)
مصطلحات موضوعية: DNA Topoisomerase IV, Topoisomerase IV, Protein subunit, Molecular Sequence Data, Biophysics, medicine.disease_cause, Biochemistry, Binding, Competitive, chemistry.chemical_compound, Adenosine Triphosphate, medicine, Escherichia coli, Amino Acid Sequence, Molecular Biology, Peptide sequence, Nuclear Magnetic Resonance, Biomolecular, biology, Topoisomerase, DNA replication, Cell Biology, biochemical phenomena, metabolism, and nutrition, Anti-Bacterial Agents, chemistry, Docking (molecular), Drug Design, biology.protein, Adenosine triphosphate
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8
المؤلفون: Priscilla Lu-Yi Teo, Mao-Yi Lei, Mun-Ling Tong, Koichi Narasaka, Shunsuke Chiba, Shu-Su Shen, Yun-Xuan Wong
المصدر: Tetrahedron Letters. 50:3161-3163
مصطلحات موضوعية: chemistry.chemical_classification, Organic Chemistry, chemistry.chemical_element, Biochemistry, Medicinal chemistry, chemistry.chemical_compound, chemistry, Thiourea, Intramolecular force, Drug Discovery, Nucleophilic substitution, Organic chemistry, Imidazole, Carbon, Thioamide
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9دورية أكاديمية
المؤلفون: Kwiatkowski, Jacek, Boping Liu, Hui Ying Tee, Doris, Guoying Chen, Ahmad, Nur Huda Binte, Yun Xuan Wong, Zhi Ying Poh, Shi Hua Ang, Sum Wai Tan, Eldwin, Ong, Esther H. Q., Dinie, Nurul, Poulsen, Anders, Pendharkar, Vishal, Sangthongpitag, Kanda, May Ann Lee, Sepramaniam, Sugunavathi, Soo Yei Ho, Cherian, Joseph, Hill, Jeffrey, Keller, Thomas H.
المصدر: Journal of Medicinal Chemistry; 5/24/2018, Vol. 61 Issue 10, p4386-4396, 11p
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10
المؤلفون: Mao-Yi Lei, Shu-Su Shen, Yun-Xuan Wong, Shunsuke Chiba, Koichi Narasaka, Priscilla Lu-Yi Teo, Mun-Ling Tong
المصدر: ChemInform. 40
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Thiourea, Intramolecular force, Nucleophilic substitution, chemistry.chemical_element, Imidazole, General Medicine, Medicinal chemistry, Carbon, Thioamide