نتائج البحث - "Yungui Zhou"

1

دورية أكاديمية

Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

المؤلفون: Chao Wang, Li Fan, Rabia R. Khawaja, Bangyan Liu, Lihong Zhan, Lay Kodama, Marcus Chin, Yaqiao Li, David Le, Yungui Zhou, Carlo Condello, Lea T. Grinberg, William W. Seeley, Bruce L. Miller, Sue-Ann Mok, Jason E. Gestwicki, Ana Maria Cuervo, Wenjie Luo, Li Gan

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1f855da0da7c4c2995106bb45af63b8f

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2

دورية أكاديمية

A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain

المؤلفون: Lihong Zhan, Li Fan, Lay Kodama, Peter Dongmin Sohn, Man Ying Wong, Gergey Alzaem Mousa, Yungui Zhou, Yaqiao Li, Li Gan

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: microglia, adult microglial progenitors, csf1r signaling, Mac2, microglia homeostasis, myeloid cells, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/51796; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/38de165a5edb4d8e822dcdefe18cdd9b

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3

دورية أكاديمية

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.

المؤلفون: Lihong Zhan, Grietje Krabbe, Fei Du, Ian Jones, Meredith C Reichert, Maria Telpoukhovskaia, Lay Kodama, Chao Wang, Seo-Hyun Cho, Faten Sayed, Yaqiao Li, David Le, Yungui Zhou, Yin Shen, Brian West, Li Gan

المصدر: PLoS Biology, Vol 17, Iss 2, p e3000134 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

URL الوصول: https://doaj.org/article/20a6e03402384b01a796884e40f2c6d4

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4

دورية أكاديمية

Fibrinogen inhibits sonic hedgehog signaling and impairs neonatal cerebellar development after blood-brain barrier disruption.

المؤلفون: Weaver, Olivia, Gano, Dawn, Yungui Zhou, Hosung Kim, Tognatta, Reshmi, Zhaoqi Yan, Jae Kyu Ryu, Brandt, Caroline, Basu, Trisha, Grana, Martin, Cabriga, Belinda, Alzamora, Maria del Pilar S., Barkovich, A. James, Akassoglou, Katerina, Petersen, Mark A.

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 7/30/2024, Vol. 121 Issue 31, p1-7, 18p

مصطلحات موضوعية: HEDGEHOG signaling proteins, PREMATURE infants, CENTRAL nervous system, BRAIN injuries, BLOOD-brain barrier

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BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis

المؤلفون: Hans Lassmann, Rosa Meza-Acevedo, Jae K. Ryu, Belinda S. Cabriga, Reuben Thomas, Katerina Akassoglou, Mark A. Petersen, Zhaoqi Yan, Yungui Zhou, Eric A. Bushong, Reshmi Tognatta, Anke Meyer-Franke, Mario Merlini, Mark H. Ellisman, Andrew S. Mendiola, Abinaya Muthusamy

المصدر: Brain : a journal of neurology, vol 144, iss 8
Brain

مصطلحات موضوعية: Neurodegenerative, multiple sclerosis, Cardiovascular, Medical and Health Sciences, neuroinflammation, Mice, Homeostasis, Myelin Sheath, AcademicSubjects/SCI01870, Chemistry, Cell Differentiation, RNA sequencing, Cell biology, Oligodendroglia, medicine.anatomical_structure, Spinal Cord, 5.1 Pharmaceuticals, Bone Morphogenetic Proteins, Neurological, Quinolines, Stem Cell Research - Nonembryonic - Non-Human, Astrocyte, Multiple Sclerosis, Mice, Transgenic, Cell fate determination, Bone morphogenetic protein, Blood–brain barrier, Autoimmune Disease, medicine, Animals, Remyelination, Neuroinflammation, Progenitor, Oligodendrocyte Precursor Cells, Neurology & Neurosurgery, Multiple sclerosis, Psychology and Cognitive Sciences, Neurosciences, Bone Morphogenetic Protein Receptors, blood-brain barrier, Stem Cell Research, medicine.disease, Brain Disorders, Pyrimidines, Pyrazoles, AcademicSubjects/MED00310, Neurology (clinical), promyelinating drugs, Reports

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8585c10d6c53364230dc6a3fe244c9e9
https://doi.org/10.1093/brain/awab106

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Preliminary Exploration of the Initial Diagnostic Prediction Model of Moderate Coronavirus Disease 2019 (2019-nCoV) Based on Clinical Data

المؤلفون: Zhendong Jiang, Jiajia Zhao, Ritian Zha, Jiancheng Hao, Ping Wang, Ruiping Xuan, Lei Zhang, Shangming Chen, Jingmin Gui, Wensheng Jiang, Xiaoqin Liu, Yungui Zhou

المصدر: Open Journal of Nursing. 11:7-16

مصطلحات موضوعية: Lesion, myalgia, Diagnostic methods, Mathematical equations, Coronavirus disease 2019 (COVID-19), business.industry, Incidence (epidemiology), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medicine, medicine.symptom, business, Nuclear medicine, Procalcitonin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a8cf96c72d9c47aa773f9548b2c38579
https://doi.org/10.4236/ojn.2021.111002

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Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

المصدر: Cell, vol 185, iss 4

مصطلحات موضوعية: Proteomics, Aging, interactome, Neurodegenerative, Alzheimer's Disease, Severity of Illness Index, Medical and Health Sciences, protein-protein interaction, synapse, 2.1 Biological and endogenous factors, Protein Interaction Maps, Amino Acids, APEX, Aetiology, Alzheimer's Disease Related Dementias (ADRD), Neurons, Stem Cell Research - Induced Pluripotent Stem Cell - Human, neurodegeneration, Brain, Biological Sciences, Mitochondria, Frontotemporal Dementia (FTD), Tauopathies, Frontotemporal Dementia, Neurological, Disease Progression, Tau secretion, Subcellular Fractions, Protein Binding, Induced Pluripotent Stem Cells, tau Proteins, General Biochemistry, Genetics and Molecular Biology, Protein Domains, Alzheimer Disease, Acquired Cognitive Impairment, Humans, Biotinylation, Cell Nucleus, Stem Cell Research - Induced Pluripotent Stem Cell, affinity purification mass spectrometry, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Stem Cell Research, Brain Disorders, Synapses, Nerve Degeneration, Mutation, Mutant Proteins, Dementia, Tau, Energy Metabolism, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7c2ab524e7117a3fe6db828aa20a56
https://escholarship.org/uc/item/9tw4v44t

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Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia

المؤلفون: Yungui Zhou, Lihong Zhan, Ben A. Bahr, Sheng Ding, David Le, Maria Telpoukhovskaia, Min Xie, Jon Iker Etchegaray, Yaqiao Li, Faten A. Sayed, Matthew Bogyo, Li Gan, Kai Liu

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Granulin, lcsh:Medicine, Transcriptome, Gene Knockout Techniques, Mice, Progranulins, 0302 clinical medicine, Cysteine Proteases, lcsh:Science, Cells, Cultured, Multidisciplinary, Microglia, Drug discovery, Cell Cycle, Neurodegenerative diseases, Neurodegeneration, High-throughput screening, High-Throughput Nucleotide Sequencing, Cell cycle, Naltrexone, Cell biology, medicine.anatomical_structure, Drug screening, Frontotemporal Dementia, medicine.symptom, Haploinsufficiency, Inflammation, Biology, Models, Biological, Article, Small Molecule Libraries, 03 medical and health sciences, mental disorders, medicine, Animals, Humans, Cathepsin, Sequence Analysis, RNA, Gene Expression Profiling, lcsh:R, medicine.disease, Disease Models, Animal, 030104 developmental biology, Bucladesine, Gene Expression Regulation, lcsh:Q, Lysosomes, 030217 neurology & neurosurgery, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b717edaa83f83d26f6fc4d526cda2c
http://link.springer.com/article/10.1038/s41598-020-70534-9

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9

AD-linked R47H- TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation

المصدر: Sci Transl Med

مصطلحات موضوعية: Membrane Glycoproteins, Hyperactivation, TREM2, Brain, General Medicine, Disease, Biology, Article, Mice, Alzheimer Disease, Mutation, Mutation (genetic algorithm), Myeloid cells, Cancer research, Animals, Humans, Female, Microglia, Receptors, Immunologic, Receptor, Proto-Oncogene Proteins c-akt, Protein kinase B, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bfaa5135ff0c66a29779f068ec0946
https://doi.org/10.1126/scitranslmed.abe3947

10

Tau interactome mapping reveals dynamic processes in synapses and mitochondria associated with neurodegenerative disease

مصطلحات موضوعية: mental disorders, medicine, Premovement neuronal activity, Secretion, Proximity ligation assay, Mitochondrion, Biology, medicine.disease, Ascorbic acid, Induced pluripotent stem cell, Interactome, Frontotemporal dementia, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::303a9fc9607f6dbfc63168365dd49ee3
https://doi.org/10.1101/2021.06.17.448349

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