المؤلفون: Ryutaro Tamura, Yusuke Sabu, Tadahaya Mizuno, Seiya Mizuno, Satoshi Nakano, Mitsuyoshi Suzuki, Daiki Abukawa, Shunsaku Kaji, Yoshihiro Azuma, Ayano Inui, Tatsuya Okamoto, Seiichi Shimizu, Akinari Fukuda, Seisuke Sakamoto, Mureo Kasahara, Satoru Takahashi, Hiroyuki Kusuhara, Yoh Zen, Tomohiro Ando, Hisamitsu Hayashi

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/6e3497d067f34e50bfe570fb76233f5d

المؤلفون: Hiroyuki Kusuhara, Mitsuyoshi Suzuki, Yoshiki Miura, Shuhei Osaka, Yusuke Sabu, Hisamitsu Hayashi, Ayumu Mizutani, Satoshi Nakano, Kei Minowa, Yuka Hiraoka, Tadahaya Mizuno, Saeko Hirai, Toshiaki Shimizu

المصدر: Molecular Genetics and Metabolism. 132:220-226

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Glutamine, Endocrinology, Diabetes and Metabolism, Administration, Oral, Biological Availability, 030105 genetics & heredity, Pharmacology, Biochemistry, Phenylbutyrate, Eating, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Pharmacokinetics, Oral administration, Genetics, Humans, Medicine, Amino Acids, Urea Cycle Disorders, Inborn, Molecular Biology, Meal, business.industry, Middle Aged, Phenylbutyrates, Crossover study, Healthy Volunteers, Regimen, Urea cycle, Female, business, Amino Acids, Branched-Chain, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04653bd512aa0f39372d07d505462602
https://doi.org/10.1016/j.ymgme.2021.02.002

المؤلفون: Eitaro Aihara, Ayumu Mizutani, Nakayuki Naritaka, Hiroyuki Kusuhara, Yusuke Sabu, Aiko Fukami, Kenneth D. R. Setchell, Christopher N. Mayhew, Takanori Takebe, Akihiro Asai, Shuhei Osaka, Hisamitsu Hayashi, Masahide Sakabe, Kokoro Sakabe, Takahisa Nakamura, Eriko Kishimoto, Yueh Chiang Hu, Wujuan Zhang, Stacey S. Huppert

المصدر: Stem Cell Reports

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Induced Pluripotent Stem Cells, Cell Culture Techniques, Biology, Models, Biological, digestive system, Biochemistry, Article, PFIC2, Bile Acids and Salts, 03 medical and health sciences, 0302 clinical medicine, Cholestasis, hepatic differentiation, bile acid transport, Genetics, medicine, Humans, CRISPR genome editing, Induced pluripotent stem cell, ATP Binding Cassette Transporter, Subfamily B, Member 11, Cells, Cultured, Gene Editing, iPSC, Bile acid, Progressive familial intrahepatic cholestasis, Biological Transport, Cell Differentiation, Cell Biology, medicine.disease, Bile Salt Export Pump, Cell biology, 030104 developmental biology, bile acid synthesis, Paracellular transport, Mutation, Hepatocytes, progressive familial intrahepatic cholestasis, CRISPR-Cas Systems, Stem cell, 030217 neurology & neurosurgery, Intracellular, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70ab469ffecf140b481001d135e4c59
https://doi.org/10.1016/j.stemcr.2020.12.008

المؤلفون: Tatsuki Mizuochi, Satoshi Watanabe, Yusuke Sabu, Hiroyuki Kusuhara, Kazuhiko Bessho, Koichi Ito, Daiki Abukawa, Mika Sasaki, Yukihiro Inomata, Ayano Inui, M Kasahara, Akinari Fukuda, Hisamitsu Hayashi, Kei Minowa, Sotaro Naoi, Koji Muroya, Ayumu Mizutani, Yuki Oya, Yoshihiro Azuma, Mitsuyoshi Suzuki, Shogo Ito, Hajime Takikawa, Satoshi Nakano, Shunsaku Kaji, Takao Togawa

المصدر: Hepatology Communications

مصطلحات موضوعية: Adult, Male, Adolescent, CD14, Benign Recurrent Intrahepatic Cholestasis, Lipopolysaccharide Receptors, Antigens, Differentiation, Myelomonocytic, Receptors, Cell Surface, Liver disease, Young Adult, Cholestasis, Antigens, CD, medicine, Humans, Child, Adenosine Triphosphatases, Hepatology, Cluster of differentiation, business.industry, Macrophages, Progressive familial intrahepatic cholestasis, Original Articles, medicine.disease, In vitro, Interleukin-10, Liver, Mutagenesis, Child, Preschool, Immunology, Mutation, Female, Original Article, business, CD163

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e60a8a6c0556cfb64b27c426964ad61
https://pubmed.ncbi.nlm.nih.gov/33437900

المؤلفون: Kazuhiko Bessho, Hiroyuki Kusuhara, Atsuko Nakazawa, Hironori Kusano, Ayano Inui, Saeko Hirai, Satoshi Nakano, Hisamitsu Hayashi, Kei Minowa, Satoshi Watanabe, Masayoshi Kage, Yusuke Sabu, Yoh Zen, Yoshihiro Azuma, Toshiaki Shimizu, Shuhei Osaka, Hiroki Kondou, Ken Tanikawa, Hidefumi Nakamura, Takeshi Kimura, Mitsuyoshi Suzuki

المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, lcsh:Medicine, Antineoplastic Agents, Cholestasis, Intrahepatic, Paediatric research, Gastroenterology, Phenylbutyrate, Article, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Oral administration, Internal medicine, medicine, Humans, Tissue Distribution, Adverse effect, lcsh:Science, Child, Liver diseases, ATP Binding Cassette Transporter, Subfamily B, Member 11, Multidisciplinary, medicine.diagnostic_test, business.industry, lcsh:R, Progressive familial intrahepatic cholestasis, Infant, Drug Synergism, medicine.disease, Prognosis, Phenylbutyrates, Diet, Regimen, 030104 developmental biology, Postprandial, Child, Preschool, Mutation, 030211 gastroenterology & hepatology, lcsh:Q, Female, Clinical pharmacology, Liver function tests, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbb66f87b204c203ff08be77f352c7a
http://europepmc.org/articles/PMC6863819

المؤلفون: Atsuko Nakazawa, Hironori Kusano, Yoshihiro Azuma, Shuhei Osaka, Hidefumi Nakamura, Hiroyuki Kusuhara, Toshiaki Shimizu, Ken Tanikawa, Hisamitsu Hayashi, Kei Minowa, Takeshi Kimura, Yusuke Sabu, Kazuhiko Bessho, Mitsuyoshi Suzuki, Hiroki Kondou, Satoshi Nakano, Satoshi Watanabe, Yoh Zen, Masayoshi Kage, Saeko Hirai, Ayano Inui

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: medicine.medical_specialty, medicine.diagnostic_test, business.industry, Progressive familial intrahepatic cholestasis, medicine.disease, Phenylbutyrate, Clinical trial, Regimen, Postprandial, Oral administration, Internal medicine, medicine, business, Liver function tests, Adverse effect

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::16fb70b4413fa0ec37dc1235b4da921a
https://doi.org/10.2139/ssrn.3321476

المؤلفون: Masayoshi Kage, Hisamitsu Hayashi, Daigo Kajikawa, Jun Fujishiro, Hiroyuki Kusuhara, Ryo Sumazaki, Hiroki Wada, Yusuke Sabu, Kazuo Imagawa, Ken Tanikawa, Toyoichiro Kudo

المصدر: Journal of human genetics. 63(5)

مصطلحات موضوعية: 0301 basic medicine, Male, Models, Molecular, medicine.medical_specialty, Protein Conformation, Benign Recurrent Intrahepatic Cholestasis, Cholestasis, Intrahepatic, Biology, medicine.disease_cause, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Cholestasis, Internal medicine, Genetics, medicine, Missense mutation, Humans, ABCB11, Genetics (clinical), ATP Binding Cassette Transporter, Subfamily B, Member 11, Alleles, Genetic Association Studies, Mutation, Homozygote, Progressive familial intrahepatic cholestasis, Sequence Analysis, DNA, Jaundice, medicine.disease, Phenotype, 030104 developmental biology, Endocrinology, Disease Progression, Hepatocytes, 030211 gastroenterology & hepatology, Female, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4742fe7ca2d1bd6288e441ad894942
https://pubmed.ncbi.nlm.nih.gov/29507376