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المؤلفون: Palma FR; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Medicine and Biophysics, Medical College of Wisconsin, Milwaukee, WI, 5322, USA., Ratti BA; Universidade Estadual de Maringa, Avenida Colombo 5790, Maringa, PR, CEP 87020-900, Brazil., Paviani V; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Medicine and Biophysics, Medical College of Wisconsin, Milwaukee, WI, 5322, USA., Coelho DR; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Medicine and Biophysics, Medical College of Wisconsin, Milwaukee, WI, 5322, USA., Miguel R; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Danes JM; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Medicine and Biophysics, Medical College of Wisconsin, Milwaukee, WI, 5322, USA., Zaichik SV; Department of Medicine, University of Illinois at Chicago, 909 S. Wolcott Avenue, COMRB 1131, Chicago, IL, 60612, USA., de Abreu AL; Universidade Estadual de Maringa, Avenida Colombo 5790, Maringa, PR, CEP 87020-900, Brazil.; Department of Medicine, University of Illinois at Chicago, 909 S. Wolcott Avenue, COMRB 1131, Chicago, IL, 60612, USA., Silva SO; Universidade Estadual de Maringa, Avenida Colombo 5790, Maringa, PR, CEP 87020-900, Brazil., Chen Y; Department of Medicine and Biophysics, Medical College of Wisconsin, Milwaukee, WI, 5322, USA.; Blood Research Institute, Versiti, Milwaukee, WI, 53226, USA., Silverstein RL; Department of Medicine and Biophysics, Medical College of Wisconsin, Milwaukee, WI, 5322, USA.; Blood Research Institute, Versiti, Milwaukee, WI, 53226, USA., Karan U; Department of Medicine, Emory University School of Medicine, 615 Michael Street NE, Atlanta, GA, 30322, USA., Jones DP; Department of Medicine, Emory University School of Medicine, 615 Michael Street NE, Atlanta, GA, 30322, USA., Bonini MG; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. marcelo.bonini@northwestern.edu.; Department of Medicine and Biophysics, Medical College of Wisconsin, Milwaukee, WI, 5322, USA. marcelo.bonini@northwestern.edu.

المصدر: Oncogene [Oncogene] 2021 Sep; Vol. 40 (36), pp. 5455-5467. Date of Electronic Publication: 2021 Jul 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene

مواضيع طبية MeSH: Metformin*/pharmacology , Energy Metabolism*/drug effects , AMP-Activated Protein Kinases*/metabolism , Glycolysis*/drug effects , Carbohydrate Metabolism*/drug effects, Humans ; Cell Line, Tumor ; Electron Transport Complex I/metabolism ; Pyruvic Acid/metabolism ; Ketone Bodies/metabolism ; Mitochondria/metabolism ; Mitochondria/drug effects ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Neoplasms/pathology