المؤلفون: Amy R. Howell, Kevin Shannon, Anthony D. Long, Predovic M, Bihua Huang, Remsberg, Inguva A, Micah J. Niphakis, Nhi Ngo, Radu M. Suciu, Stewart K. Richardson, Kenneth M. Lum, Hanigan Tw, Firestone Aj, Cassandra L. Henry, Benjamin F. Cravatt, Zambetti Na

مصطلحات موضوعية: chemistry.chemical_classification, Membrane, Enzyme, chemistry, Palmitoylation, Proteome, Lipase inhibitors, medicine, Myeloid leukemia, Cancer, Oncogenicity, medicine.disease, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ee779cfd11259dabc59a9be1a2d0354a
https://doi.org/10.1101/2020.05.21.108316

المؤلفون: Remsberg JR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Suciu RM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Zambetti NA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Hanigan TW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Firestone AJ; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Inguva A; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Long A; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Ngo N; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Lum KM; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Henry CL; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Richardson SK; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Predovic M; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Huang B; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Dix MM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Howell AR; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Niphakis MJ; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA. MIIP@lundbeck.com., Shannon K; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. Kevin.Shannon@ucsf.edu.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. Kevin.Shannon@ucsf.edu., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. cravatt@scripps.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2021 Aug; Vol. 17 (8), pp. 856-864. Date of Electronic Publication: 2021 Apr 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane/*metabolism , Hydrolases/*metabolism , Leukemia, Myeloid, Acute/*metabolism , Leukemia, Promyelocytic, Acute/*metabolism , ras Proteins/*metabolism, Cell Proliferation ; Cells, Cultured ; Humans ; Leukemia, Myeloid, Acute/pathology ; Leukemia, Promyelocytic, Acute/pathology ; Lipoylation ; Microsomes, Liver/chemistry ; Microsomes, Liver/metabolism ; Molecular Structure

المؤلفون: Zambetti NA; Department of Pediatrics.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Firestone AJ; Department of Pediatrics.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Remsberg JR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA., Huang BJ; Department of Pediatrics.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Wong JC; Department of Pediatrics.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA., Long AM; Department of Pediatrics., Predovic M; Department of Pediatrics., Suciu RM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA., Inguva A; Department of Pediatrics., Kogan SC; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA.; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA., Haigis KM; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Boston, MA; and.; Department of Medicine, Harvard University Medical School, Boston, MA., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA., Shannon K; Department of Pediatrics.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA.

المصدر: Blood [Blood] 2020 May 14; Vol. 135 (20), pp. 1772-1782.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Cell Transformation, Neoplastic/*genetics , Hematologic Neoplasms/*genetics , Hematopoiesis/*genetics , Lipoylation/*genetics , Monomeric GTP-Binding Proteins/*genetics , Monomeric GTP-Binding Proteins/*metabolism, Amino Acid Substitution ; Animals ; Aspartic Acid/genetics ; Cell Transformation, Neoplastic/metabolism ; Cells, Cultured ; Glycine/genetics ; Hematologic Neoplasms/metabolism ; Hematopoietic Stem Cells/physiology ; Metabolic Networks and Pathways/genetics ; Mice ; Mice, Transgenic ; Palmitic Acid/metabolism

المؤلفون: Zambetti NA; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Ping Z; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Chen S; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Kenswil KJG; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Mylona MA; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Sanders MA; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Hoogenboezem RM; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Bindels EMJ; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Adisty MN; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Van Strien PMH; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., van der Leije CS; Department of Internal Medicine, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Westers TM; Department of Hematology, VU University Medical Center, Cancer Center Amsterdam, Amsterdam 1081HV, the Netherlands., Cremers EMP; Department of Hematology, VU University Medical Center, Cancer Center Amsterdam, Amsterdam 1081HV, the Netherlands., Milanese C; Department of Molecular Genetics, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Mastroberardino PG; Department of Molecular Genetics, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., van Leeuwen JPTM; Department of Internal Medicine, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., van der Eerden BCJ; Department of Internal Medicine, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Touw IP; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., Kuijpers TW; Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Academic Medical Centre (AMC), University of Amsterdam (UvA), Amsterdam 1105AZ, the Netherlands., Kanaar R; Departments of Genetics and Radiation Oncology, Cancer Genomics Center, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands., van de Loosdrecht AA; Department of Hematology, VU University Medical Center, Cancer Center Amsterdam, Amsterdam 1081HV, the Netherlands., Vogl T; Institute of Immunology, University of Münster, Münster 48149, Germany., Raaijmakers MHGP; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam 3015CN, the Netherlands. Electronic address: m.h.g.raaijmakers@erasmusmc.nl.

المصدر: Cell stem cell [Cell Stem Cell] 2016 Nov 03; Vol. 19 (5), pp. 613-627. Date of Electronic Publication: 2016 Sep 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Disease Progression*, Hematopoietic Stem Cells/*pathology , Inflammation/*pathology , Leukemia/*pathology , Mesenchymal Stem Cells/*pathology , Precancerous Conditions/*pathology, Animals ; Bone Marrow Diseases/pathology ; Bone and Bones/abnormalities ; Bone and Bones/pathology ; DNA Repair ; Exocrine Pancreatic Insufficiency/pathology ; Gene Deletion ; Hematopoietic Stem Cells/metabolism ; Humans ; Integrases/metabolism ; Leukemia/metabolism ; Lipomatosis/pathology ; Mesenchymal Stem Cells/metabolism ; Mice ; Mitochondria/metabolism ; Oxidative Stress ; Pathogen-Associated Molecular Pattern Molecules/metabolism ; Precancerous Conditions/metabolism ; Proteins/metabolism ; Risk Factors ; S100 Proteins/genetics ; S100 Proteins/metabolism ; Shwachman-Diamond Syndrome ; Signal Transduction ; Sp7 Transcription Factor ; Stem Cell Niche ; Toll-Like Receptors/metabolism ; Transcription Factors/metabolism ; Treatment Outcome ; Tumor Suppressor Protein p53/metabolism

SCR Disease Name: Shwachman syndrome

المؤلفون: Chen S; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Zambetti NA; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Bindels EM; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Kenswill K; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Mylona AM; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Adisty NM; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hoogenboezem RM; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Sanders MA; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Cremers EM; Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands., Westers TM; Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands., Jansen JH; Laboratory of Hematology, Department of Laboratory Medicine, Radboud University Nijmegen Medical Centre and Centre for Molecular Life Sciences, Nijmegen, The Netherlands., van de Loosdrecht AA; Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands., Raaijmakers MH; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

المصدر: Leukemia [Leukemia] 2016 Sep; Vol. 30 (9), pp. 1938-42. Date of Electronic Publication: 2016 Apr 25.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome*, Inflammation/*genetics , Myelodysplastic Syndromes/*genetics, Gene Expression Profiling ; Gene Regulatory Networks/genetics ; Gene Regulatory Networks/immunology ; High-Throughput Nucleotide Sequencing ; Humans ; Mesoderm/physiopathology ; Myelodysplastic Syndromes/physiopathology ; Sequence Analysis, RNA

المؤلفون: Zambetti NA; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands., Bindels EM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands., Van Strien PM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands., Valkhof MG; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands Current address: Laboratory for Cell Therapy, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands., Adisty MN; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands., Hoogenboezem RM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands., Sanders MA; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands., Rommens JM; Program in Genetics & Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, ON, Canada., Touw IP; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands., Raaijmakers MH; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands m.h.g.raaijmakers@erasmusmc.nl.

المصدر: Haematologica [Haematologica] 2015 Oct; Vol. 100 (10), pp. 1285-93. Date of Electronic Publication: 2015 Jul 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation/*genetics , Cell Lineage/*genetics , Hematopoietic Stem Cells/*metabolism , Myeloid Cells/*cytology , Myeloid Cells/*metabolism , Neutropenia/*genetics , Proteins/*genetics, Animals ; Apoptosis/genetics ; Bone Marrow Diseases/genetics ; CCAAT-Enhancer-Binding Proteins/genetics ; CCAAT-Enhancer-Binding Proteins/metabolism ; Cell Cycle/genetics ; Disease Models, Animal ; Exocrine Pancreatic Insufficiency/genetics ; Gene Deletion ; Hematopoiesis/genetics ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/cytology ; Lipomatosis/genetics ; Mice ; Mice, Knockout ; Shwachman-Diamond Syndrome ; Signal Transduction ; Tumor Suppressor Protein p53/metabolism

SCR Disease Name: Shwachman syndrome

المؤلفون: Zambetti NA, Raaijmakers MH

المصدر: Haematologica [Haematologica] 2013 Jan; Vol. 98 (1), pp. 1.

نوع المنشور: News

بيانات الدورية: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE

مواضيع طبية MeSH: Endothelium/*cytology , Endothelium/*physiology , Hematopoietic Stem Cells/*physiology , Selectins/*physiology, Animals ; Humans ; Selectins/isolation & purification