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1
المؤلفون: Zdeněk Vavřina, Pavla Perlíková, Nemanja Milisavljević, Florian Chevrier, Miroslav Smola, Joshua Smith, Milan Dejmek, Vojtěch Havlíček, Miloš Buděšínský, Radek Liboska, Lenka Vaneková, Jiří Brynda, Evzen Boura, Pavlína Řezáčová, Michal Hocek, Gabriel Birkuš
المصدر: Journal of Medicinal Chemistry. 65:14082-14103
مصطلحات موضوعية: Mice, Drug Discovery, Animals, Humans, Membrane Proteins, Cytokines, Molecular Medicine, Interferons, Nucleotides, Cyclic, Ligands, Nucleotidyltransferases
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2
المؤلفون: Miroslav Smola, Martin Zavřel, Gabriel Birkus, Vilém Charvát, Milan Kožíšek, Ondrej Gutten, Zahra Aliakbar Tehrani, Lubomír Rulíšek, Zdeněk Vavřina, Evzen Boura
المصدر: Biochemistry. 60:607-620
مصطلحات موضوعية: Protein Conformation, Stacking, Crystallography, X-Ray, medicine.disease_cause, Biochemistry, 03 medical and health sciences, Protein Domains, medicine, Humans, Point Mutation, Binding site, 0303 health sciences, Mutation, Binding Sites, Molecular Structure, Hydrogen bond, Chemistry, 030302 biochemistry & molecular biology, Membrane Proteins, Hydrogen Bonding, Isothermal titration calorimetry, Ligand (biochemistry), Sting, Biophysics, Nucleotides, Cyclic, Protein ligand
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3
المؤلفون: Tomáš Lášek, Magdalena Petrová, Ivana Košiová, Ondřej Šimák, Miloš Buděšínský, Jaroslav Kozák, Jan Snášel, Zdeněk Vavřina, Gabriel Birkuš, Ivan Rosenberg, Ondřej Páv
المصدر: Bioorganicmedicinal chemistry. 56
مصطلحات موضوعية: Oligoribonucleotides, Dose-Response Relationship, Drug, Adenine Nucleotides, Organic Chemistry, Clinical Biochemistry, Organophosphonates, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, Drug Discovery, Endoribonucleases, Molecular Medicine, Humans, Nucleic Acid Conformation, Molecular Biology
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4
المؤلفون: Florian Chevrier, Monika Staś, Radek Liboska, Miroslav Smola, Lucie Holá, Evzen Boura, Ondrej Gutten, Martin Zavřel, Lubomír Rulíšek, Barbora Novotna, Zdeněk Vavřina, Juraj Dobiaš, Gabriel Birkus, Miloš Buděšínský
المصدر: Biochemistry. 60(48)
مصطلحات موضوعية: Bacillus thuringiensis, medicine.disease_cause, Crystallography, X-Ray, Biochemistry, Molecular mechanics, Substrate Specificity, Structure-Activity Relationship, medicine, Escherichia coli, Humans, Thermotoga maritima, Vibrio cholerae, chemistry.chemical_classification, biology, Chemistry, Nucleotides, Signal transducing adaptor protein, Membrane Proteins, biology.organism_classification, Immunity, Innate, Sting, Enzyme, Stimulator of interferon genes, Second messenger system, Leukocytes, Mononuclear, Cytokines, Quantum Theory
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5
المؤلفون: Tomáš Lášek, Magdalena Petrová, Ivana Košiová, Ondřej Šimák, Miloš Buděšínský, Jaroslav Kozák, Jan Snášel, Zdeněk Vavřina, Gabriel Birkuš, Ivan Rosenberg, Ondřej Páv
المصدر: Bioorganic & Medicinal Chemistry. 58:116654
مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry
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6
المؤلفون: Zahra Aliakbar Tehrani, Martin Zavřel, Tomáš Jandušík, Andrea Brázdová, Ondrej Gutten, Radim Nencka, Gabriel Birkus, Miloš Buděšínský, Ondřej Páv, Evžen Bouřa, Markéta Pimková Polidarová, Barbora Novotna, Radek Liboska, Zdeněk Vavřina, Milan Dejmek, Miroslav Smola, Jiří Brynda, Ivan Štěpánek, Lubomír Rulíšek, Lenka Vaneková
المصدر: Journal of medicinal chemistry. 62(23)
مصطلحات موضوعية: Chemistry, Protein Conformation, Signal transducing adaptor protein, Membrane Proteins, IκB kinase, Cell biology, Sting, Structure-Activity Relationship, HEK293 Cells, Gene Expression Regulation, Interferon, Stimulator of interferon genes, Drug Discovery, Second messenger system, medicine, Leukocytes, Mononuclear, Molecular Medicine, Cytokines, Humans, Biological Assay, Computer Simulation, Nucleotides, Cyclic, IRF3, Interferon regulatory factors, medicine.drug