المؤلفون: Sheehan SM; Lilly Research Laboratories, A Division of Eli Lilly and Company, Indianapolis, IN 46285, USA. SHEEHAN_SCOTT@LILLY.COM, Mest HJ, Watson BM, Klimkowski VJ, Timm DE, Cauvin A, Parsons SH, Shi Q, Canada EJ, Wiley MR, Ruehter G, Evers B, Petersen S, Blaszczak LC, Pulley SR, Margolis BJ, Wishart GN, Renson B, Hankotius D, Mohr M, Zechel JC, Michael Kalbfleisch J, Dingess-Hammond EA, Boelke A, Weichert AG

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2007 Mar 15; Vol. 17 (6), pp. 1765-8. Date of Electronic Publication: 2006 Dec 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Dipeptidyl-Peptidase IV Inhibitors*, Protease Inhibitors/*chemical synthesis , Protease Inhibitors/*pharmacology, Animals ; Binding Sites ; Computer Simulation ; Crystallography, X-Ray ; Dipeptidyl Peptidase 4/blood ; Drug Evaluation, Preclinical ; Hydrogen Bonding ; Male ; Models, Molecular ; Molecular Conformation ; Protease Inhibitors/chemistry ; Rats ; Rats, Wistar ; Spectrometry, Fluorescence