المؤلفون: Yarnall MTN; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA., Ioannidi EI; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA.; ETH Zürich, Zürich, Switzerland., Schmitt-Ulms C; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA., Krajeski RN; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA., Lim J; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA., Villiger L; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA., Zhou W; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA., Jiang K; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Garushyants SK; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Roberts N; Integrated DNA Technologies, Coralville, IA, USA., Zhang L; Integrated DNA Technologies, Coralville, IA, USA., Vakulskas CA; Integrated DNA Technologies, Coralville, IA, USA., Walker JA 2nd; Synthego Corporation, Redwood City, CA, USA., Kadina AP; Synthego Corporation, Redwood City, CA, USA., Zepeda AE; Synthego Corporation, Redwood City, CA, USA., Holden K; Synthego Corporation, Redwood City, CA, USA., Ma H; University of Massachusetts Chan Medical School, Worcester, MA, USA., Xie J; University of Massachusetts Chan Medical School, Worcester, MA, USA., Gao G; University of Massachusetts Chan Medical School, Worcester, MA, USA., Foquet L; Yecuris Corporation, Tualatin, OR, USA., Bial G; Yecuris Corporation, Tualatin, OR, USA., Donnelly SK; PhoenixBio USA Corporation, New York, NY, USA., Miyata Y; PhoenixBio USA Corporation, New York, NY, USA., Radiloff DR; PhoenixBio USA Corporation, New York, NY, USA., Henderson JM; TriLink Biotechnologies LLC, San Diego, CA, USA., Ujita A; TriLink Biotechnologies LLC, San Diego, CA, USA., Abudayyeh OO; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA. omarabu@mit.edu., Gootenberg JS; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA. jgoot@mit.edu.

المصدر: Nature biotechnology [Nat Biotechnol] 2023 Apr; Vol. 41 (4), pp. 500-512. Date of Electronic Publication: 2022 Nov 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*/genetics , Integrases*, Humans ; DNA Cleavage ; Gene Editing ; DNA/genetics ; DNA End-Joining Repair/genetics

المؤلفون: Zeng L; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Liu Y; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Nguyenla XH; Department of Molecular and Cellular Biology, University of California, Berkeley, CA, 94720, USA., Abbott TR; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Han M; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Zhu Y; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Chemparathy A; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Lin X; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Chen X; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Wang H; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Rane DA; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Spatz JM; Department of Pediatrics, Stanford University, Stanford, CA, 94305, USA., Jain S; University of California San Francisco, San Francisco, CA, 94143, USA., Rustagi A; Department of Medicine, Stanford University, Stanford, CA, 94305, USA., Pinsky B; Department of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Pathology, Stanford University, Stanford, CA, USA., Zepeda AE; Synthego Corporation, Redwood City, CA, USA., Kadina AP; Synthego Corporation, Redwood City, CA, USA., Walker JA 3rd; Synthego Corporation, Redwood City, CA, USA., Holden K; Synthego Corporation, Redwood City, CA, USA., Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, Chatham, Kent ME4 4TB, UK., Cochran JR; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Barron AE; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Connolly MD; Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Blish CA; Department of Medicine, Stanford University, Stanford, CA, 94305, USA.; Chan Zuckerberg BioHub, San Francisco, CA, 94158, USA., Lewis DB; Department of Pediatrics, Stanford University, Stanford, CA, 94305, USA., Stanley SA; Department of Molecular and Cellular Biology, University of California, Berkeley, CA, 94720, USA. sastanley@berkeley.edu., La Russa MF; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA. mlarussa@stanford.edu., Qi LS; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA. stanley.qi@stanford.edu.; Chan Zuckerberg BioHub, San Francisco, CA, 94158, USA. stanley.qi@stanford.edu.; Sarafan ChEM-H, Stanford University, Stanford, CA, 94305, USA. stanley.qi@stanford.edu.

المصدر: Nature communications [Nat Commun] 2022 May 19; Vol. 13 (1), pp. 2766. Date of Electronic Publication: 2022 May 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/genetics , COVID-19 Drug Treatment*, Antiviral Agents/pharmacology ; Humans ; Liposomes ; Nanoparticles

SCR Organism: SARS-CoV-2 variants