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1
المؤلفون: Vivaswath S. Ayyar, Pharavee Jaiprasart, Brian Geist, Madhu Chintala, Chyi-Hung Hsu, Zheng Huang Devine, Case Martin A, Anasuya Hazra, Weirong Wang
المصدر: British Journal of Pharmacology. 178:3943-3958
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, medicine.diagnostic_test, Chemistry, Thrombin time, Receptor–ligand kinetics, In vitro, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Thrombin, Pharmacokinetics, In vivo, Pharmacodynamics, medicine, 030217 neurology & neurosurgery, PK/PD models, medicine.drug
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المؤلفون: Guozhang Xu, Zhijie Liu, Xinkang Wang, Tianbao Lu, Renee L. DesJarlais, Tho Thieu, Jing Zhang, Zheng Huang Devine, Fuyong Du, Qiu Li, Cynthia M. Milligan, Paul Shaffer, Peder E. Cedervall, John C. Spurlino, Christopher F. Stratton, Beth Pietrak, Lawrence M. Szewczuk, Victoria Wong, Ruth A. Steele, Wouter Bruinzeel, Madhu Chintala, Jose Silva, Michael D. Gaul, Mark J. Macielag, Ravi Nargund
المصدر: Journal of medicinal chemistry. 65(15)
مصطلحات موضوعية: Dogs, Pyridines, Drug Design, Drug Discovery, Molecular Medicine, Animals, Anticoagulants, Rabbits, Factor XIa, Rats
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المؤلفون: Vivaswath S, Ayyar, Pharavee, Jaiprasart, Brian, Geist, Zheng, Huang Devine, Martin, Case, Anasuya, Hazra, Chyi-Hung, Hsu, Madhu, Chintala, Weirong, Wang
المصدر: British journal of pharmacologyREFERENCES. 178(19)
مصطلحات موضوعية: Macaca fascicularis, Thrombin, Animals, Antibodies, Monoclonal, Blood Coagulation Tests, Antibodies, Monoclonal, Humanized
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المؤلفون: Qiu Li, Madhu Chintala, Fuyong Du, Eilyn R. Lacy, Matthew Bunce, Zheng Huang Devine
المصدر: Journal of Pharmacology and Experimental Therapeutics. 371:375-384
مصطلحات موضوعية: Blood Platelets, Male, 0301 basic medicine, Pharmacology, Thrombin time, Antithrombins, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, 0302 clinical medicine, Thrombin, In vivo, medicine, Animals, Humans, Prothrombin time, Dose-Response Relationship, Drug, medicine.diagnostic_test, Chemistry, Antibodies, Monoclonal, Recombinant Proteins, Thromboelastography, Rats, Macaca fascicularis, 030104 developmental biology, Mechanism of action, Immunoglobulin G, Molecular Medicine, medicine.symptom, Ecarin clotting time, Platelet Aggregation Inhibitors, 030217 neurology & neurosurgery, Protein Binding, circulatory and respiratory physiology, medicine.drug, Partial thromboplastin time
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d855718c1a965115156f31263d0fbd6b
https://doi.org/10.1124/jpet.119.261032 -
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المؤلفون: Madhu Chintala, Matthew Bunce, Zheng Huang Devine
المصدر: Blood. 136:10-11
مصطلحات موضوعية: medicine.drug_class, business.industry, Immunology, Anticoagulant, Cell Biology, Hematology, Pharmacology, Biochemistry, Small molecule, In vitro, Human plasma, medicine, business, Whole blood
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::db6e7139becd4057044ca01f1e9c27e6
https://doi.org/10.1182/blood-2020-136378 -
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المؤلفون: Madhu Chintala, Qiu Li, Zheng Huang Devine
المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology. 38
مصطلحات موضوعية: Serine protease, biology, Chemistry, Pharmacology, medicine.disease, Fibrinogen, Thrombosis, Fibrin, Thrombin, Long acting, Hemostasis, medicine, biology.protein, Cardiology and Cardiovascular Medicine, circulatory and respiratory physiology, Discovery and development of direct thrombin inhibitors, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f6a142364bbe2948aa81f65d75396c2c
https://doi.org/10.1161/atvb.38.suppl_1.521