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1دورية أكاديمية
المؤلفون: Xiaodi Yu, Pravien Abeywickrema, Brecht Bonneux, Ishani Behera, Brandon Anson, Edgar Jacoby, Amy Fung, Suraj Adhikary, Anusarka Bhaumik, Rodrigo J. Carbajo, Suzanne De Bruyn, Robyn Miller, Aaron Patrick, Quyen Pham, Madison Piassek, Nick Verheyen, Afzaal Shareef, Priscila Sutto-Ortiz, Nina Ysebaert, Herman Van Vlijmen, Tim H. M. Jonckers, Florence Herschke, Jason S. McLellan, Etienne Decroly, Rachel Fearns, Sandrine Grosse, Dirk Roymans, Sujata Sharma, Peter Rigaux, Zhinan Jin
المصدر: Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2399-3642
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2دورية أكاديمية
المؤلفون: Martin Holan, Kathryn Tucker, Natalia Dyatkina, Hong Liu, April Kinkade, Guangyi Wang, Zhinan Jin, Marija Prhavc
المصدر: Molecules, Vol 27, Iss 8, p 2413 (2022)
مصطلحات موضوعية: HBV-antivirals, apionucleosides, DNA-polymerase inhibition, Organic chemistry, QD241-441
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Jerome Deval, Jin Hong, Guangyi Wang, Josh Taylor, Lucas K Smith, Amy Fung, Sarah K Stevens, Hong Liu, Zhinan Jin, Natalia Dyatkina, Marija Prhavc, Antitsa D Stoycheva, Vladimir Serebryany, Jyanwei Liu, David B Smith, Yuen Tam, Qingling Zhang, Martin L Moore, Rachel Fearns, Sushmita M Chanda, Lawrence M Blatt, Julian A Symons, Leo Beigelman
المصدر: PLoS Pathogens, Vol 11, Iss 6, p e1004995 (2015)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Zhinan Jin, Lucas K Smith, Vivek K Rajwanshi, Baek Kim, Jerome Deval
المصدر: PLoS ONE, Vol 8, Iss 7, p e68347 (2013)
وصف الملف: electronic resource
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5
المؤلفون: Prhavc, Martin Holan, Kathryn Tucker, Natalia Dyatkina, Hong Liu, April Kinkade, Guangyi Wang, Zhinan Jin, Marija
المصدر: Molecules; Volume 27; Issue 8; Pages: 2413
مصطلحات موضوعية: HBV-antivirals, apionucleosides, DNA-polymerase inhibition
وصف الملف: application/pdf
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6
المؤلفون: Antitsa Dimitrova Stoycheva, Leonid Beigelman, Tongqian Chen, Kenneth Shaw, Vivek K. Rajwanshi, Zhinan Jin, Andreas Jekle, Yujian Hu, Kusum Gupta, Caroline Williams, Amy Fung, Guangyi Wang, Vladimir Serebryany, Natalia B. Dyatkina, Xiangyang Wu, Marija Prhavc, Jerome Deval, David B. Smith, Wensheng Huang, Yuen Tam, Yongfei Huang
المصدر: Journal of Medicinal Chemistry. 63:10380-10395
مصطلحات موضوعية: 0303 health sciences, Chemistry, Hepatitis C virus, Guanosine, Phosphoramidate, Pharmacology, Prodrug, medicine.disease, medicine.disease_cause, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Liver disease, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Molecular Medicine, IC50, Nucleoside, 030304 developmental biology
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7
المؤلفون: Guangyi, Wang, Natalia, Dyatkina, Marija, Prhavc, Caroline, Williams, Vladimir, Serebryany, Yujian, Hu, Yongfei, Huang, Xiangyang, Wu, Tongqian, Chen, Wensheng, Huang, Vivek K, Rajwanshi, Jerome, Deval, Amy, Fung, Zhinan, Jin, Antitsa, Stoycheva, Kenneth, Shaw, Kusum, Gupta, Yuen, Tam, Andreas, Jekle, David B, Smith, Leonid, Beigelman
المصدر: Journal of medicinal chemistry. 63(18)
مصطلحات موضوعية: Male, Dogs, Animals, Humans, Female, Prodrugs, DNA-Directed RNA Polymerases, Hepacivirus, Enzyme Inhibitors, Viral Nonstructural Proteins, Virus Replication, Antiviral Agents, Guanine Nucleotides
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8
المؤلفون: Zhinan Jin, Andreas Jekle, Natalia B. Dyatkina, April Kinkade, Leo Beigelman, Shuvam Chaudhuri, Vivek K. Rajwanshi, Jerome Deval, Ishani Behera, Julian A. Symons, Kathryn Tucker, Guangyi Wang, David B. Smith
المصدر: Antiviral Research. 143:151-161
مصطلحات موضوعية: 0301 basic medicine, Adenosine, Transcription, Genetic, POLRMT, RNA, Mitochondrial, 030106 microbiology, Guanosine Monophosphate, Cytidine, Antiviral Agents, Cell Line, Mitochondrial Proteins, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Virology, medicine, Humans, Prodrugs, Nucleotide, Polymerase, Pharmacology, chemistry.chemical_classification, biology, Chemistry, Nucleosides, DNA-Directed RNA Polymerases, Prodrug, Ribonucleoside, medicine.disease, Amides, Mitochondria, Mitochondrial toxicity, 030104 developmental biology, Biochemistry, Protein Biosynthesis, Pyrazines, biology.protein, Nucleoside triphosphate, RNA, Ribonucleosides, Sofosbuvir, Transcription Initiation Site, Nucleoside
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9
المؤلفون: Jerome Deval, Zhinan Jin, Ying-Chih Chuang, C. Cheng Kao
المصدر: Virus Research
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, GII.4, genogroup II genotype 4, Transcription, Genetic, Protein Conformation, viruses, VP1, major capsid protein, Drug Evaluation, Preclinical, medicine.disease_cause, Crystallography, X-Ray, Virus Replication, Genome, PPNDS, pyridoxal-5′-phosphate-6-(2′-naphthylazo-6′-nitro-4′,8′-disulfonate, chemistry.chemical_compound, fluids and secretions, IC50, half-maximal inhibitory concentration, NIC02, a phenylthiazole carboxamide, Transcription (biology), RNA polymerase, GI–GVII, norovirus genogroup designations, VP2, minor capsid protein, Enzyme Inhibitors, ACT, 2′-amino-cytidine triphosphate, Caliciviridae Infections, virus diseases, HuNoV, human norovirus, NTP, nucleoside triphosphate, Infectious Diseases, NIC12, a pyrazolidinedione, NIC10, a triazole, HCV, hepatitis C virus, Nucleoside analogs, Caliciviridae, medicine.drug, NIC04, a pyrazole acetamide, RNA-dependent RNA polymerase, 2′-F-2′-C-MeC, 2′-fluroro-2′-C-methyl-cytidine (PSI-6130), Microbial Sensitivity Tests, Biology, Non-nucleoside inhibitor, Antiviral Agents, Article, 03 medical and health sciences, Virus inhibitors, ORF, open reading frame, Virology, medicine, Animals, Humans, MNV, murine norovirus, RdRp, RNA-dependent RNA polymerase, Nucleoside analogue, NS, nonstructural, Norovirus, RNA, biology.organism_classification, RNA-Dependent RNA Polymerase, digestive system diseases, RNA-dependent RNA polymerase (RdRp), 2CM-C, 2′-C-methyl-cytidine, Disease Models, Animal, 030104 developmental biology, chemistry, EC50, half-maximal effective concentration, RTP, ribofuranosyl 5′-triphosphate, NCT, 5-nitrocytidine triphosphate
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10
المؤلفون: Dirk Roymans, Zhinan Jin, Paul C. Jordan, Julien Sourimant, Etienne Decroly, Ysebaert Nina, Peter Rigaux, Jean-François Eléouët, Cheng Liu, Ishani Behera, Morgan S.A. Gilman, Priscila Sutto-Ortiz, Sergey Tcherniuk, Amy Fung, Jason S. McLellan
المساهمون: University of Texas at Austin [Austin], Janssen BioPharma, Janssen Infectious Diseases and Vaccines, Centre de recherches de biochimie macromoléculaire (CRBM), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-IFR122-Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay, Institut National de la Recherche Agronomique (INRA), Bioénergétique et Ingénierie des Protéines (BIP ), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Architecture et fonction des macromolécules biologiques (AFMB), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre de recherche en Biologie Cellulaire (CRBM), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA), Cancer Prevention and Research Institute of Texas [RR160023], Janssen Pharmaceutical Companies of Johnson Johnson, University of Texas College of Natural Sciences, Centre de recherche en Biologie cellulaire de Montpellier (CRBM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Cell
Cell, Elsevier, 2019, 179 (1), pp.193-204.e14. ⟨10.1016/j.cell.2019.08.014⟩
Cell, 2019, 179 (1), pp.193-204.e14. ⟨10.1016/j.cell.2019.08.014⟩مصطلحات موضوعية: Protein Conformation, alpha-Helical, RdRp, [SDV]Life Sciences [q-bio], viruses, Mutant, Acetates, medicine.disease_cause, Virus Replication, Deoxycytidine, MTase, chemistry.chemical_compound, 0302 clinical medicine, Transcription (biology), RNA polymerase, Catalytic Domain, Sf9 Cells, Polymerase, 0303 health sciences, allostery, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, ALS-8176, 3. Good health, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], Quinolines, Hydrophobic and Hydrophilic Interactions, Viral protein, Allosteric regulation, Genome, Viral, Respiratory Syncytial Virus Infections, Spodoptera, Antiviral Agents, Article, General Biochemistry, Genetics and Molecular Biology, Virus, 03 medical and health sciences, Viral Proteins, medicine, Respiratory Syncytial Virus Vaccines, Humans, Animals, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Protein Interaction Domains and Motifs, 030304 developmental biology, PRNTase, Cryoelectron Microscopy, Hydrogen Bonding, Phosphoproteins, RNA-Dependent RNA Polymerase, Virology, chemistry, Phosphoprotein, Respiratory Syncytial Virus, Human, biology.protein, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a750287027c362d95ea745753766e798
https://pubmed.ncbi.nlm.nih.gov/31672264
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