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المؤلفون: Zuzana Valnickova-Hansen, Russell P. Bowler, Line R. Thomsen, Carsten Scavenius, Ebbe Toftgaard Poulsen, Jane S. Petersen, Steen V. Petersen, Tim D. Oury, Jan J. Enghild
المصدر: Scavenius, C, Petersen, J S, Thomsen, L R, Poulsen, E T, Valnickova Hansen, Z, Bowler, R D, Oury, T D, Petersen, S V & Enghild, J J 2013, ' Murine Extracellular Superoxide Dismutase Is Converted into the Inactive Fold by the Ser195Cys Mutation. ', Biochemistry, vol. 52, no. 19, pp. 3369-3375 . https://doi.org/10.1021/bi400171b
مصطلحات موضوعية: Genetically modified mouse, Protein Folding, Spectrometry, Mass, Electrospray Ionization, Heterologous, Hamster, Mice, Transgenic, CHO Cells, Biochemistry, Mice, chemistry.chemical_compound, Cricetulus, Biosynthesis, Tandem Mass Spectrometry, In vivo, Cricetinae, Animals, Humans, Cysteine, Superoxide Dismutase, Recombinant Proteins, Cell biology, Kinetics, HEK293 Cells, Amino Acid Substitution, chemistry, Extracellular superoxide dismutase, Mutagenesis, Site-Directed, Specific activity, Active enzyme
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المؤلفون: Tim D. Oury, Zuzana Valnickova, Ebbe Toftgaard Poulsen, Torsten Nygaard Kristensen, Jan J. Enghild, Niels Chr. Nielsen, Ida B. Thøgersen, Morten Nielsen, Steen V. Petersen, Jane S. Petersen, James D. Crapo, Søren K. Moestrup, Christian Bøtcher Jacobsen
المصدر: Petersen, S V, Thøgersen, I, Valnickova, Z, Nielsen, M S, Petersen, J S, Poulsen, E T, Jacobsen, C, Oury, T D, Moestrup, S K, Crapo, J D, Nielsen, N C, Kristensen, T & Enghild, J J 2010, ' The concentration of extracellular superoxide dismutase in plasma is maintained by LRP-mediated endocytosis ', Free Radical Biology & Medicine, vol. 49, no. 5, pp. 894-9 . https://doi.org/10.1016/j.freeradbiomed.2010.06.019
مصطلحات موضوعية: Antioxidant, Metabolic Clearance Rate, medicine.medical_treatment, Endocytosis, Biochemistry, Redox, Mice, Physiology (medical), Liver tissue, Chlorocebus aethiops, medicine, Extracellular, Animals, Humans, Receptor, Superoxide Dismutase, Chemistry, Osmolar Concentration, Hep G2 Cells, Cell biology, Extracellular superoxide dismutase, COS Cells, Female, lipids (amino acids, peptides, and proteins), Oxidation-Reduction, Low Density Lipoprotein Receptor-Related Protein-1, Protein Binding, Lipoprotein
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المؤلفون: Joan L. Arolas, Laura Sanglas, Jan J. Enghild, F. Xavier Gomis-Rüth, Francesc X. Avilés, Zuzana Valnickova, Steen V. Petersen, Daniel E. Otzen, Christine R. Schar
المصدر: Journal of Biological Chemistry; Vol 285
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Biological Chemistry
Valnickova, Z, Sanglas, L, Arolas, J L, Petersen, S V, Schar, C, Otzen, D, Aviles, F X, Gomis-Ruth, F X & Enghild, J J 2010, ' Flexibility of the thrombin-activatable fibrinolysis inhibitor pro-domain enables productive binding of protein substrates ', Journal of Biological Chemistry . https://doi.org/10.1074/jbc.M110.150342مصطلحات موضوعية: Carboxypeptidase B2, Stereochemistry, medicine.medical_treatment, Peptide, Plasma protein binding, 030204 cardiovascular system & hematology, Crystallography, X-Ray, Biochemistry, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Protein structure, medicine, Structure–activity relationship, Animals, Humans, Protease Inhibitors, Protein Structure, Quaternary, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Metalloproteinase, Protease, biology, Active site, Cell Biology, Carboxypeptidase, Protein Structure, Tertiary, chemistry, Protein Structure and Folding, biology.protein, Cattle, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ae7c9e31d5af014981c3d992e2b246
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المؤلفون: Kasper Runager, Torben Møller-Pedersen, Gordon K. Klintworth, Ida B. Thøgersen, Heririk Karring, Jan J. Enghild, Zuzana Valnickova
المصدر: Karring, H, Runager, K, Valnickova, Z, Thøgersen, I B, Møller-Pedersen, T, Klintworth, G K & Enghild, J J 2010, ' Differential expression and processing of transforming growth factor beta induced protein (TGFBIp) in the normal human cornea during postnatal development and aging ', Experimental Eye Research, vol. 90, pp. 57-62 . https://doi.org/10.1016/j.exer.2009.09.011
Karring, H, Runager, K, Valnickova, Z, Thøgersen, I, Møller-Pedersen, T, Klintworth, G K & Enghild, J J 2010, ' Differential expression and processing of transforming growth factor beta induced protein (TGFBIp) in the normal human cornea during postnatal development and aging ', Experimental Eye Research, vol. 90, no. 1, pp. 57-62 . https://doi.org/10.1016/j.exer.2009.09.011مصطلحات موضوعية: Male, Gene isoform, Aging, Adolescent, Immunoblotting, Corneal dystrophy, Protein degradation, Article, Cornea, Extracellular matrix, Young Adult, Cellular and Molecular Neuroscience, Transforming Growth Factor beta, medicine, Humans, Electrophoresis, Gel, Two-Dimensional, Child, Aged, 80 and over, Gel electrophoresis, Extracellular Matrix Proteins, Chromatography, biology, Chemistry, Infant, Transforming growth factor beta, Middle Aged, medicine.disease, eye diseases, Sensory Systems, Cell biology, Ophthalmology, medicine.anatomical_structure, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, biology.protein, Female, sense organs, TGFBI
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المؤلفون: Torsten Nygaard Kristensen, Gordon K. Klintworth, Kasper Runager, F. Xavier Gomis-Rüth, Jan J. Enghild, Raquel García-Castellanos, Niels Chr. Nielsen, Zuzana Valnickova
المصدر: Acta Crystallographica Section F Structural Biology and Crystallization Communications; Vol 65
Runager, K, García-Castellanos, R, Valnickova, Z, Kristensen, T, Nielsen, N C, Klintworth, G K, Gomis-Rüth, F X & Enghild, J J 2009, ' Purification, crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor beta-induced protein (TGFBIp) ', Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, vol. 65, no. Pt 3, pp. 299-303 . https://doi.org/10.1107/S1744309109005016
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Recombinant protein, Mutant, Biophysics, medicine.disease_cause, Crystallography, X-Ray, Biochemistry, Chromatography, Affinity, law.invention, Extracellular matrix, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, law, Transforming Growth Factor beta, Genetics, medicine, Extracellular, Humans, 030304 developmental biology, 0303 health sciences, Mutation, Extracellular Matrix Proteins, biology, Wild type, Transforming growth factor beta, Condensed Matter Physics, Recombinant Proteins, 3. Good health, Crystallization Communications, 030221 ophthalmology & optometry, biology.protein, Recombinant DNA, Electrophoresis, Polyacrylamide Gel, Mutant Proteins, Crystallization, Corneal dystrophy, Transforming growth factor
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المؤلفون: Kanchan Anand, Trine Christensen, Josep Vendrell, K. Ulrich Wendt, Herman Schreuder, Irantzu Pallarès, Zuzana Valnickova, Jan J. Enghild, Francesc X. Avilés
المصدر: Journal of Biological Chemistry. 283:29416-29423
مصطلحات موضوعية: Models, Molecular, Carboxypeptidase B2, Antifibrinolytic, Intrinsic activity, Protein Conformation, medicine.drug_class, Molecular Sequence Data, Molecular Conformation, Crystallography, X-Ray, Models, Biological, Biochemistry, Fibrin, Thrombin, Zymogen, medicine, Animals, Humans, Amino Acid Sequence, Molecular Biology, Ions, Binding Sites, Sequence Homology, Amino Acid, biology, Chemistry, Mutagenesis, Active site, Cell Biology, Heparin, Protein Structure and Folding, Mutagenesis, Site-Directed, biology.protein, Cattle, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525508b670a9637e9b05ad2d4d46d9ce
https://doi.org/10.1074/jbc.m804003200 -
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المؤلفون: Peter Højrup, Ida B. Thøgersen, Trine Christensen, Peter Durand Skottrup, Jan J. Enghild, Zuzana Valnickova
المصدر: Valnickova, Z, Thøgersen, I, Skottrup, P, Christensen, T, Højrup, P & Enghild, J J 2006, ' Post-translational modifications of human thrombin-activatable fibrinolysis inhibitor (TAFI): evidence for a large shift in the isoelectric point and reduced solubility upon activation. ', Biochemistry, vol. 5, no. 45, pp. 1525-35 .
Valnickova, Z, Christensen, T, Skottrup, P, Thøgersen, I B, Højrup, P & Enghild, J J 2006, ' Post-translational Modifications of Human Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) : Evidence for a Large Shift in the Isoelectric Point and Reduced Solubility upon Activation ', Biochemistry, vol. 45, pp. 1525-1535 . https://doi.org/10.1021/bi051956vمصطلحات موضوعية: Carboxypeptidase B2, Glycan, Glycosylation, Sensitivity and Specificity, Biochemistry, Mass Spectrometry, Polysaccharides, Pi, Humans, Human Thrombin, Disulfides, Isoelectric Point, Solubility, Fibrinolysis inhibitor, chemistry.chemical_classification, biology, Enzyme, Isoelectric point, chemistry, Posttranslational modification, biology.protein, Peptides, Protein Processing, Post-Translational, Chromatography, Liquid
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المؤلفون: Katelyn F. Leahy, Zuzana Valnickova-Hansen, John M. Hartney, Carsten Scavenius, Richard K.P. Benninger, Jan J. Enghild, Fabienne Gally, Rebecca E. Oberley-Deegan, Michael R. Weaver, Beata Kosmider, Richard J. Johnson, Timothy Stidham, Angela K. Zimmermann, Russell P. Bowler, Eva Nozik-Grayck, David A. Goldstrohm
المساهمون: Institut de Biologie du Développement de Marseille (IBDM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Circulation: Cardiovascular Genetics
Circulation: Cardiovascular Genetics, American Heart Association, 2014, 7 (5), pp.659-66. ⟨10.1161/CIRCGENETICS.113.000504⟩
Circulation: Cardiovascular Genetics, 2014, 7 (5), pp.659-66. ⟨10.1161/CIRCGENETICS.113.000504⟩مصطلحات موضوعية: medicine.medical_specialty, Genotype, SOD3, Alveolar lung disease, Hypertension, Pulmonary, Glycine, Mice, Transgenic, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Lung injury, Arginine, Polymorphism, Single Nucleotide, Antioxidants, Article, Mice, Risk Factors, Internal medicine, Genetics, medicine, Extracellular, Animals, Humans, Genetic Predisposition to Disease, Lung, Genetics (clinical), Cardiopulmonary disease, medicine.diagnostic_test, business.industry, Heparin, Superoxide Dismutase, Sepharose, Sequence Analysis, DNA, respiratory system, medicine.disease, Pulmonary hypertension, 3. Good health, Mice, Inbred C57BL, Bronchoalveolar lavage, Endocrinology, medicine.anatomical_structure, Immunology, Cardiology and Cardiovascular Medicine, business, Bronchoalveolar Lavage Fluid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1426d13508b6b61d8f59d7654f89cb1
https://hal.archives-ouvertes.fr/hal-01112272 -
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المؤلفون: Zuzana Valnickova, Henrik Karring, Ida B. Thøgersen, Kristian W. Sanggaard, Jan J. Enghild
المصدر: Sanggaard, K W, Karring, H, Valnickova, Z, Thøgersen, I B & Enghild, J J 2005, ' The TSG-6 and IαI Interaction Promotes a Transesterification Cleaving the Protein-Glycosaminoglycan-Protein (PGP) Cross-link ', Journal of Biological Chemistry, vol. 280, pp. 11936-11942 . https://doi.org/10.1074/jbc.M409016200
مصطلحات موضوعية: Glycosylation, Stereochemistry, Molecular Sequence Data, Biochemistry, Glycosaminoglycan, chemistry.chemical_compound, Residue (chemistry), Alpha-Globulins, Humans, Chondroitin, Amino Acid Sequence, Molecular Biology, Peptide sequence, Glycosaminoglycans, TSG-6, Membrane Glycoproteins, Chemistry, Cross-link, Proteins, Esters, Cell Biology, Transesterification, Molecular Weight, Trypsin Inhibitor, Kunitz Soybean, Cell Adhesion Molecules
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e0f416da4c1798ad425dff01dd4a71
https://doi.org/10.1074/jbc.m409016200 -
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المؤلفون: Jan J. Enghild, Tim D. Oury, Anne V. Due, Steen V. Petersen, Zuzana Valnickova, James D. Crapo
المصدر: Biochemistry. 43:14275-14281
مصطلحات موضوعية: chemistry.chemical_classification, Physiological function, Biology, medicine.disease_cause, Biochemistry, Amino acid, Extracellular superoxide dismutase, chemistry, Complementary DNA, medicine, Rabbit plasma, Protein disulfide-isomerase, Oxidative stress, Cysteine