المؤلفون: van der Welle REN; Section Cell Biology, Center for Molecular Medicine, Institute of Biomembranes, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Jobling R; Department of Pediatrics, Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada., Burns C; Department of Biological Sciences, Division of Natural Sciences and Mathematics, University of Denver, Denver, CO, USA., Sanza P; Section Cell Biology, Center for Molecular Medicine, Institute of Biomembranes, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van der Beek JA; Section Cell Biology, Center for Molecular Medicine, Institute of Biomembranes, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Fasano A; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, ON, Canada.; Division of Neurology, University of Toronto, Toronto, ON, Canada.; Krembil Brain Institute, Toronto, ON, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada., Chen L; Department of Biological Sciences, Division of Natural Sciences and Mathematics, University of Denver, Denver, CO, USA., Zwartkruis FJ; Section Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Zwakenberg S; Section Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Griffin EF; Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, USA.; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, Nathan Shock Center for Basic Research in the Biology of Aging, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA., Ten Brink C; Section Cell Biology, Center for Molecular Medicine, Institute of Biomembranes, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Veenendaal T; Section Cell Biology, Center for Molecular Medicine, Institute of Biomembranes, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Liv N; Section Cell Biology, Center for Molecular Medicine, Institute of Biomembranes, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van Ravenswaaij-Arts CMA; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Lemmink HH; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Pfundt R; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands., Blaser S; Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, ON, Canada., Sepulveda C; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, ON, Canada.; Division of Neurology, University of Toronto, Toronto, ON, Canada., Lozano AM; Krembil Brain Institute, Toronto, ON, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.; Department of Neurosurgery, Toronto Western Hospital, UHN, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada., Yoon G; Department of Pediatrics, Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada., Santiago-Sim T; GeneDx, Inc, Gaithersburg, MD, USA., Asensio CS; Department of Biological Sciences, Division of Natural Sciences and Mathematics, University of Denver, Denver, CO, USA., Caldwell GA; Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, USA.; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, Nathan Shock Center for Basic Research in the Biology of Aging, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA., Caldwell KA; Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, USA.; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, Nathan Shock Center for Basic Research in the Biology of Aging, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA., Chitayat D; Department of Pediatrics, Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.; The Prenatal Diagnosis and Medical Genetics Program, Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON, Canada., Klumperman J; Section Cell Biology, Center for Molecular Medicine, Institute of Biomembranes, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

المصدر: EMBO molecular medicine [EMBO Mol Med] 2021 May 07; Vol. 13 (5), pp. e13258. Date of Electronic Publication: 2021 Apr 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: EMBO Press Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Neurodegenerative Diseases*/genetics, Animals ; Autophagy ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics ; Caenorhabditis elegans/genetics ; HeLa Cells ; Humans ; Lysosomes/metabolism ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Protein Transport ; Vesicular Transport Proteins/metabolism

المؤلفون: Glykofridis IE; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Cancer Center Amsterdam, Amsterdam, Netherlands., Knol JC; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, Amsterdam, Netherlands., Balk JA; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Cancer Center Amsterdam, Amsterdam, Netherlands., Westland D; University Medical Center Utrecht, Center for Molecular Medicine, Molecular Cancer Research, Universiteitsweg, Utrecht, Netherlands., Pham TV; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, Amsterdam, Netherlands., Piersma SR; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, Amsterdam, Netherlands., Lougheed SM; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, Amsterdam, Netherlands., Derakhshan S; Princess Máxima Center for Pediatric Oncology, Oncode Institute, Heidelberglaan, Utrecht, Netherlands., Veen P; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Cancer Center Amsterdam, Amsterdam, Netherlands., Rooimans MA; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Cancer Center Amsterdam, Amsterdam, Netherlands., van Mil SE; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Cancer Center Amsterdam, Amsterdam, Netherlands., Böttger F; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, Amsterdam, Netherlands., Poddighe PJ; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Amsterdam, Netherlands., van de Beek I; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Amsterdam, Netherlands., Drost J; Princess Máxima Center for Pediatric Oncology, Oncode Institute, Heidelberglaan, Utrecht, Netherlands., Zwartkruis FJ; University Medical Center Utrecht, Center for Molecular Medicine, Molecular Cancer Research, Universiteitsweg, Utrecht, Netherlands., de Menezes RX; NKI-AvL, Biostatistics Unit, Amsterdam, Netherlands., Meijers-Heijboer HE; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Cancer Center Amsterdam, Amsterdam, Netherlands., Houweling AC; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Amsterdam, Netherlands., Jimenez CR; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, Amsterdam, Netherlands., Wolthuis RM; Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Clinical Genetics, Cancer Center Amsterdam, Amsterdam, Netherlands.

المصدر: ELife [Elife] 2021 Jan 18; Vol. 10. Date of Electronic Publication: 2021 Jan 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Carrier Proteins/*genetics , Epithelial Cells/*metabolism , Kidney/*metabolism , Proto-Oncogene Proteins/*genetics , Tumor Suppressor Proteins/*genetics, Carrier Proteins/metabolism ; Germ-Line Mutation ; Humans ; Interferons/metabolism ; Proto-Oncogene Proteins/metabolism ; Tumor Suppressor Proteins/metabolism

المؤلفون: Bruurs LJM; Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van der Net MC; Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Zwakenberg S; Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Rosendahl Huber AKM; Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Post A; Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Zwartkruis FJ; Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Bos JL; Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands J.L.Bos@umcutrecht.nl.

المصدر: Molecular and cellular biology [Mol Cell Biol] 2018 May 29; Vol. 38 (12). Date of Electronic Publication: 2018 May 29 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8109087 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5549 (Electronic) Linking ISSN: 02707306 NLM ISO Abbreviation: Mol Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane/*metabolism , Cell Polarity/*physiology , Microvilli/*metabolism , PTEN Phosphohydrolase/*metabolism , Protein Tyrosine Phosphatase, Non-Receptor Type 13/*genetics, Animals ; CRISPR-Cas Systems/genetics ; Cell Line, Tumor ; Epithelial Cells/physiology ; Gene Knockout Techniques ; HEK293 Cells ; Humans ; Male ; Mice ; Microvilli/genetics ; Neoplasms/pathology ; PTEN Phosphohydrolase/genetics

المؤلفون: Bruurs LJM; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Zwakenberg S; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., van der Net MC; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Zwartkruis FJ; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Bos JL; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands J.L.Bos@umcutrecht.nl.

المصدر: Molecular and cellular biology [Mol Cell Biol] 2017 Mar 17; Vol. 37 (7). Date of Electronic Publication: 2017 Mar 17 (Print Publication: 2017).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8109087 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5549 (Electronic) Linking ISSN: 02707306 NLM ISO Abbreviation: Mol Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Polarity* , Signal Transduction*, Enterocytes/*cytology , Enterocytes/*metabolism , cdc42 GTP-Binding Protein/*metabolism, Cell Line ; Cell Membrane/metabolism ; HEK293 Cells ; Humans ; Microvilli/metabolism ; Protein Binding ; Tubulin/metabolism ; rho-Specific Guanine Nucleotide Dissociation Inhibitors

المؤلفون: Bruurs LJ; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, Netherlands., Donker L; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, Netherlands., Zwakenberg S; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, Netherlands., Zwartkruis FJ; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, Netherlands., Begthel H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3508 AD Utrecht, Netherlands., Knisely AS; Institute of Liver Studies, King's College Hospital, London SE5 9RS, England, UK., Posthuma G; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, Netherlands., van de Graaf SF; Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, 1105 AZ Amsterdam, Netherlands., Paulusma CC; Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre, 1105 AZ Amsterdam, Netherlands., Bos JL; Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, Netherlands J.L.Bos@umcutrecht.nl.

المصدر: The Journal of cell biology [J Cell Biol] 2015 Sep 28; Vol. 210 (7), pp. 1055-63.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Adenosine Triphosphatases/*metabolism , Cell Polarity/*physiology , Enterocytes/*metabolism , Membrane Lipids/*metabolism , Phospholipid Transfer Proteins/*metabolism , Signal Transduction/*physiology , cdc42 GTP-Binding Protein/*metabolism, Adenosine Triphosphatases/genetics ; Animals ; Cell Line ; Enterocytes/cytology ; Humans ; Membrane Lipids/genetics ; Mice ; Phospholipid Transfer Proteins/genetics ; cdc42 GTP-Binding Protein/genetics

المؤلفون: Groenewoud MJ; Molecular Cancer Research, Centre for Biomedical Genetics and Cancer Genomics Centre, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands., Zwartkruis FJ

المصدر: Open biology [Open Biol] 2013 Dec 18; Vol. 3 (12), pp. 130185. Date of Electronic Publication: 2013 Dec 18.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Royal Society Pub Country of Publication: England NLM ID: 101580419 Publication Model: Electronic Cited Medium: Internet ISSN: 2046-2441 (Electronic) Linking ISSN: 20462441 NLM ISO Abbreviation: Open Biol Subsets: MEDLINE

مواضيع طبية MeSH: Homeostasis*, Mammals/*physiology , Mitochondria/*physiology , Multiprotein Complexes/*physiology , Neuropeptides/*physiology , Sirolimus/*metabolism , TOR Serine-Threonine Kinases/*physiology, Animals ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/physiology ; Gene Expression Regulation ; Glycolysis ; Humans ; Mechanistic Target of Rapamycin Complex 1 ; Mitochondrial Proteins/physiology ; Reactive Oxygen Species/metabolism ; Signal Transduction/physiology ; Transcription Factors/metabolism

المؤلفون: Magliozzi R; Hubrecht Institute-KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands., Low TY; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands; The Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., Weijts BG; Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands., Cheng T; Hubrecht Institute-KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands., Spanjaard E; Hubrecht Institute-KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands., Mohammed S; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands; The Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., van Veen A; Department of Physiological Chemistry and Center for Biomedical Genetics, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands., Ovaa H; Division of Cell Biology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands., de Rooij J; Hubrecht Institute-KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands., Zwartkruis FJ; Department of Physiological Chemistry and Center for Biomedical Genetics, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands., Bos JL; Department of Physiological Chemistry and Center for Biomedical Genetics, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands., de Bruin A; Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands., Heck AJ; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands; The Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., Guardavaccaro D; Hubrecht Institute-KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands. Electronic address: d.guardavaccaro@hubrecht.eu.

المصدر: Developmental cell [Dev Cell] 2013 Dec 09; Vol. 27 (5), pp. 574-85. Date of Electronic Publication: 2013 Nov 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

مواضيع طبية MeSH: Casein Kinase Ialpha/*metabolism , Cell Movement/*physiology , Epithelial Cells/*cytology , Guanine Nucleotide Exchange Factors/*metabolism , I-kappa B Kinase/*metabolism , Nerve Tissue Proteins/*metabolism , Signal Transduction/*physiology , Zebrafish Proteins/*metabolism, Animals ; Animals, Genetically Modified ; Breast Neoplasms ; Cell Line, Tumor ; Female ; HEK293 Cells ; Heterografts ; Humans ; Male ; Phosphorylation/physiology ; SKP Cullin F-Box Protein Ligases/metabolism ; Zebrafish

المؤلفون: Groenewoud MJ; Molecular Cancer Research, Centre for Biomedical Genetics and Cancer Genomics Centre, University Medical Center Utrecht, Utrecht, The Netherlands., Goorden SM, Kassies J, Pellis-van Berkel W, Lamb RF, Elgersma Y, Zwartkruis FJ

المصدر: PloS one [PLoS One] 2013 Nov 26; Vol. 8 (11), pp. e81649. Date of Electronic Publication: 2013 Nov 26 (Print Publication: 2013).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Fibroblasts/*metabolism , Monomeric GTP-Binding Proteins/*deficiency , Multiprotein Complexes/*metabolism , Neuropeptides/*deficiency , TOR Serine-Threonine Kinases/*metabolism, Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Cell Line ; Female ; Gene Expression ; Mechanistic Target of Rapamycin Complex 1 ; Mice ; Mice, Knockout ; Monomeric GTP-Binding Proteins/genetics ; Multiprotein Complexes/antagonists & inhibitors ; Neuropeptides/genetics ; Pregnancy ; RNA Interference ; Ras Homolog Enriched in Brain Protein ; Regulatory-Associated Protein of mTOR ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases/antagonists & inhibitors

المؤلفون: De Rubeis S; VIB Center for Biology of Disease, KULeuven, 3000 Leuven, Belgium; Center for Human Genetics and Leuven Institute for Neuroscience and Disease (LIND), KULeuven, 3000 Leuven, Belgium., Pasciuto E, Li KW, Fernández E, Di Marino D, Buzzi A, Ostroff LE, Klann E, Zwartkruis FJ, Komiyama NH, Grant SG, Poujol C, Choquet D, Achsel T, Posthuma D, Smit AB, Bagni C

المصدر: Neuron [Neuron] 2013 Sep 18; Vol. 79 (6), pp. 1169-82.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Dendritic Spines/*genetics , Nerve Tissue Proteins/*metabolism , Neurons/*ultrastructure , Protein Biosynthesis/*genetics , RNA, Messenger/*metabolism, Adaptor Proteins, Signal Transducing/chemistry ; Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Age Factors ; Aminoquinolines/pharmacology ; Analysis of Variance ; Animals ; Brain-Derived Neurotrophic Factor/pharmacology ; Carbazoles/pharmacology ; Cells, Cultured ; Cerebral Cortex/cytology ; Chromatography, Liquid ; DNA-Binding Proteins/metabolism ; Dendritic Spines/drug effects ; Dendritic Spines/ultrastructure ; Enzyme Inhibitors/pharmacology ; Fragile X Mental Retardation Protein/genetics ; Fragile X Mental Retardation Protein/metabolism ; Fragile X Mental Retardation Protein/ultrastructure ; Gene Expression Regulation/genetics ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Immunoprecipitation ; In Vitro Techniques ; Indole Alkaloids/pharmacology ; Luminescent Proteins/metabolism ; Male ; Mental Disorders/genetics ; Meta-Analysis as Topic ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microscopy, Immunoelectron ; Nerve Tissue Proteins/chemistry ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/ultrastructure ; Neurons/drug effects ; Protein Biosynthesis/drug effects ; Pyrimidines/pharmacology ; Synaptosomes/drug effects ; Synaptosomes/metabolism ; Synaptosomes/ultrastructure ; Tandem Mass Spectrometry ; Time Factors ; Transcription Factors/metabolism ; Transfection

المؤلفون: Zwartkruis FJ; Molecular Cancer Research, Centre for Biomedical Genetics and Cancer Genomics Centre, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands. G.J.T.Zwartkruis@umcutrecht.nl, Burgering BM

المصدر: Cell research [Cell Res] 2013 Aug; Vol. 23 (8), pp. 982-3. Date of Electronic Publication: 2013 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9425763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-7838 (Electronic) Linking ISSN: 10010602 NLM ISO Abbreviation: Cell Res Subsets: MEDLINE

مواضيع طبية MeSH: Endocytosis/*physiology , ras Proteins/*metabolism, Caveolin 1/metabolism ; Clathrin/metabolism ; Glucose/metabolism ; Glutamine/metabolism ; Humans ; Lysosomes/metabolism ; Mechanistic Target of Rapamycin Complex 1 ; Multiprotein Complexes/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; TOR Serine-Threonine Kinases/metabolism ; src-Family Kinases/metabolism