المؤلفون: Kazuhiro Ooi, Kazunori Mizuno, Tomonori Ueno, David Dickens, Rosalind E. Jenkins, Shuichi Kawashiri, Kentaro Ide, Francesco Falciani, Keiko Sakai, Shunji Hattori, Yuki Taga, Takao Sakai, Takako Sasaki, Sanai Takahashi

المصدر: The Journal of Biological Chemistry
Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Aging, extracellular signal–regulated kinase, Hyp, hydroxyproline, Cellular homeostasis, ERK, extracellular signal–regulated kinase, TGF-β, transforming growth factor-beta, Biochemistry, Tendons, Extracellular matrix, Mice, Cell Movement, Homeostasis, pAb, polyclonal antibody, Pseudopodia, Extracellular Signal-Regulated MAP Kinases, Pro-Hyp, prolyl-4-hydroxyproline, biology, Gly, glycine, Chemistry, Integrin beta1, Stem Cells, Cell Differentiation, Dipeptides, Up-Regulation, ECM, extracellular matrix, Cell biology, TNMD, tenomodulin, SI-Pro-Hyp, stable isotopically labeled Pro-Hyp, 13C515N1-Pro-Hyp, scleraxis, PEPT1, peptide transporter 1, Pro, proline, MXX, Mohawk homeobox, SOX9, SRY-box transcription factor 9, Type I collagen, Research Article, prolyl-hydroxyproline, collagen-derived peptide, extracellular matrix, Motility, cell motility, Collagen Type I, Leu, leucine, Ala, alanine, 03 medical and health sciences, FBS, fetal bovine serum, Extracellular, Animals, RNA, Messenger, Molecular Biology, Cell Proliferation, SCXGFP, Scx promoter–driven GFP, 030102 biochemistry & molecular biology, SCX, scleraxis, MEK, MAPK kinase, Chemotaxis, Cell Biology, Transforming growth factor beta, IPA, ingenuity pathway analysis, adult tendon cells, Tenomodulin, Tenocytes, 030104 developmental biology, biology.protein, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112ed79f665ca87965e1fa4805bf0916
https://doi.org/10.1016/j.jbc.2021.100819

المؤلفون: Ide K; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Takahashi S; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Sakai K; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Taga Y; Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan., Ueno T; Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan., Dickens D; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Jenkins R; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Falciani F; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Sasaki T; Department of Biochemistry, Faculty of Medicine, Oita University, Oita, Japan., Ooi K; Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan., Kawashiri S; Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan., Mizuno K; Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan., Hattori S; Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan., Sakai T; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK. Electronic address: sakait@liverpool.ac.uk.

المصدر: The Journal of biological chemistry [J Biol Chem] 2021 Jul; Vol. 297 (1), pp. 100819. Date of Electronic Publication: 2021 May 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cell Movement/*drug effects , Dipeptides/*pharmacology , Homeostasis/*drug effects , Integrin beta1/*metabolism , Pseudopodia/*metabolism , Tendons/*cytology, Aging ; Animals ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Mice ; Pseudopodia/drug effects ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Stem Cells/cytology ; Stem Cells/drug effects ; Stem Cells/metabolism ; Tenocytes/cytology ; Tenocytes/drug effects ; Up-Regulation/drug effects