المؤلفون: Francesco Bavo, Marco Pallavicini, Rebecca Appiani, Cristiano Bolchi

المصدر: Molecules, Vol 26, Iss 12, p 3603 (2021)

مصطلحات موضوعية: (S)-nicotine, nAChR, N-methyl-pyrrolidinyl, selectivity, alpha4beta2, alpha3beta4, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/12/3603; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/92948bab41844f2c9c2aa4b0446d9fe9

المؤلفون: Mazurov, Anatoly^Aff10, Yohannes, Daniel^Aff11

المساهمون: Bernstein, Peter R., Series editor^Aff1, Buschauer, Armin, Series editor^Aff2, Georg, Gunda I., Series editor^Aff3, Lowe, John A., Series editor^Aff4, Stilz, Ulrich, Series editor^Aff5, Supuran, Claudiu T., Series editor^Aff6, Saxena, Anil Kumar, Series editor^Aff7, Celanire, Sylvain, editor^Aff8, Poli, Sonia, editor^Aff9

المصدر: Small Molecule Therapeutics for Schizophrenia. 13:213-253

المؤلفون: Francesco Bavo, Marco Pallavicini, Cristiano Bolchi, Rebecca Appiani

المصدر: Bavo, F, Pallavicini, M, Appiani, R & Bolchi, C 2021, ' Determinants for α4β2 vs. α3β4 subtype selectivity of pyrrolidine-based nachrs ligands : A computational perspective with focus on recent cryo-em receptor structures ', Molecules, vol. 26, no. 12, 3603 . https://doi.org/10.3390/molecules26123603
Molecules
Molecules, Vol 26, Iss 3603, p 3603 (2021)
Volume 26
Issue 12

مصطلحات موضوعية: Alpha3beta4, Pyrrolidines, Pyridines, Pharmaceutical Science, N-methyl-pyrrolidinyl, Receptors, Nicotinic, Ligands, 01 natural sciences, Synaptic Transmission, Pyrrolidine, Analytical Chemistry, Docking, chemistry.chemical_compound, QD241-441, alpha4beta2, Drug Discovery, Databases, Genetic, Alpha4beta2, Selectivity, Nicotinic Agonists, Receptor, Cryo-EM, 0303 health sciences, NAChR, Molecular Docking Simulation, Nicotinic agonist, Chemistry (miscellaneous), docking, Molecular Medicine, benzodioxane, Agonist, medicine.drug_class, Structural similarity, Stereochemistry, Benzodioxane, Ether, (S)-nicotine, nAChR, Article, 03 medical and health sciences, Structure-Activity Relationship, medicine, Animals, Humans, Physical and Theoretical Chemistry, 030304 developmental biology, Binding Sites, 010405 organic chemistry, Organic Chemistry, Cryoelectron Microscopy, selectivity, 0104 chemical sciences, Rats, chemistry, Docking (molecular), cryo-EM, alpha3beta4

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512c7f5ba85f13f25e44ad6f04bd9fa1
https://curis.ku.dk/ws/files/285447571/molecules_26_03603_v2.pdf

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المؤلفون: D. Ergun, Wisam Toma, Deniz Bagdas, M.I. Damaj, Marvin K. Schulte, Asti Jackson

المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Deney Hayvanları Yetiştirme ve Araştırma Merkezi., Bağdaş, Deniz

المصدر: Eur J Pain

مصطلحات موضوعية: Disease mkodels, animal, Male, 0301 basic medicine, Beta-2, Unclassified drug, Mouse, Receptors, Nicotinic, Pharmacology, Ligands, Neuropathic pain, Nicotinic receptor alpha4beta2, Indole Alkaloids, Antinociception, Nicotine, Nicotinic receptor, Mice, chemistry.chemical_compound, Sensitivity, 0302 clinical medicine, Anesthesiology, Abt-594, Drug activity, Allosterism, Nicotinic Agonists, Priority journal, Desformylflustrabromine, Morphine, Nicotinic agent, Stoichiometry, Hydrocarbons, Brominated, Antiallodynic effect, Megadose, Nicotinic agonist, Indole alkaloid, Clinical neurology, Brominated hydrocarbon, Bromine derivative, Locomotion, medicine.drug, Epibatidine, Nicotinic Receptors, Mecamylamine, Agonist, Allosteric modulator, Efficacy, medicine.drug_class, Drug potentiation, Neurosciences & neurology, Concentration response, Allodynia, Partial agonist, Article, Chronic constriction injury, Low drug dose, Rotarod test, 03 medical and health sciences, Allosteric Regulation, Discriminative-stimulus, medicine, Animals, Animal model, Animal experiment, Cholinergic activity, Animal, Disease model, business.industry, Motor dysfunction, Neurosciences, Nonhuman, Drug effect, Disease Models, Animal, Metabolism, 030104 developmental biology, Anesthesiology and Pain Medicine, nervous system, chemistry, Motor coordination, Neuralgia, Cholinergic, sense organs, business, Controlled study, Neuroscience, 030217 neurology & neurosurgery, NS9283

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6893fa75c309f10eb00917b9c22e563
https://doi.org/10.1002/ejp.1092

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المؤلفون: Sara Garcia-Ratés, Antoni Riera, Salomé Llabrés, Jorge Camarasa, José I. Borrell, David Pubill, Elena Escubedo, Edgar Cristóbal-Lecina, F. Javier Luque

المساهمون: Universitat de Barcelona, Universitat Ramon Llull. IQS

المصدر: Recercat. Dipósit de la Recerca de Catalunya
instname
RECERCAT (Dipòsit de la Recerca de Catalunya)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)

مصطلحات موضوعية: MDMA, Stereochemistry, Receptors nicotínics, Receptor Up-Regulation, Receptors, Nicotinic, PC12 Cells, Nicotina--Receptors, Structure-Activity Relationship, Ecstasy (Drug), Drug Discovery, mental disorders, medicine, Animals, Receptor up-regulation, Alpha4Beta2 nicotinic receptor, 3,4-Methylenedioxyamphetamine, 54 - Química, Pharmacology, Binding Sites, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Estructura molecular, Amphetamines, Stereoselective synthesis, Stereoisomerism, Èxtasi (Droga), General Medicine, Enantioselective binding, Amfetamines, Radioligand Assay, Rats, Nicotinic acetylcholine receptor, Nicotinic agonist, Docking (molecular), Epibatidine, Nicotinic receptors, Molecular modelling, Enantiomer, Molecular structure, psychological phenomena and processes, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cf27628087816c4487370a076d4ac9
http://hdl.handle.net/2445/111900

المؤلفون: Lipovsek, M., Im, G.J., Franchini, L.F., Pisciottano, F., Katz, E., Fuchs, P.A., Elgoyhen, A.B.

المصدر: Proc. Natl. Acad. Sci. U. S. A. 2012;109(11):4308-4313
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN

مصطلحات موضوعية: Cell Membrane Permeability, Ligand-gated channel, Evolution, nicotinic receptor alpha4beta2, cell receptor, channel gating, chicken, mammal, animal cell, Receptors, Nicotinic, phylogeny, hair cell, Ionotropic receptor, Evolution, Molecular, Xenopus laevis, synapse, vertebrate, calcium transport, Hair Cells, Auditory, calcium ion, Animals, Humans, neurotransmission, hyperpolarization, Vertebrata, Likelihood Functions, nonhuman, Rattus, article, artificial chromosome, Acetylcholine, Recombinant Proteins, cation, Rats, Protein Subunits, priority journal, Mammalia, Outer hair cell, Oocytes, Calcium, Chickens

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3056::4802b0c2080c1c556915ff8c2952d19c

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