المؤلفون: Gu M; School of Chemistry, Zhengzhou University, Zhengzhou, 450001, China., Zhang H; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Henan Key Laboratory of Nanomedicine for Targeting Diagnosis and Treatment, Zhengzhou, 450001, China., Liu Y; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Henan Key Laboratory of Nanomedicine for Targeting Diagnosis and Treatment, Zhengzhou, 450001, China., Li X; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Henan Key Laboratory of Nanomedicine for Targeting Diagnosis and Treatment, Zhengzhou, 450001, China., Lv M; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Henan Key Laboratory of Nanomedicine for Targeting Diagnosis and Treatment, Zhengzhou, 450001, China., Zhao J; School of Chemistry, Zhengzhou University, Zhengzhou, 450001, China; Department of Pharmaceutical and Chemical Engineering Technology, Zhengzhou University of Industrial Technology, Zhengzhou, 451100, China. Electronic address: zjinan@zzu.edu.cn., Zhang J; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China; Henan Key Laboratory of Nanomedicine for Targeting Diagnosis and Treatment, Zhengzhou, 450001, China. Electronic address: zhangjunli0927@zzu.edu.cn.

المصدر: Analytica chimica acta [Anal Chim Acta] 2024 Jul 25; Vol. 1314, pp. 342779. Date of Electronic Publication: 2024 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4324 (Electronic) Linking ISSN: 00032670 NLM ISO Abbreviation: Anal Chim Acta Subsets: MEDLINE

مواضيع طبية MeSH: Fluorescence Resonance Energy Transfer* , Alzheimer Disease*/diagnosis , Alzheimer Disease*/metabolism , Extracellular Vesicles*/chemistry , Amyloid beta-Peptides*/analysis , Amyloid beta-Peptides*/blood , Tetraspanin 30*/metabolism , Gold*/chemistry , Metal Nanoparticles*/chemistry, Animals ; Mice ; Humans ; Peptide Fragments/analysis ; Peptide Fragments/blood ; Peptide Fragments/chemistry ; Polymers/chemistry ; Indoles/chemistry ; Limit of Detection

المؤلفون: González Díaz A; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Cataldi R; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Mannini B; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; Department of Experimental and Clinical Biomedical Sciences Mario Serio, University of Florence, 50134 Florence, Italy., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2024 Jul 17; Vol. 15 (14), pp. 2586-2599. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides*/chemistry , Amyloid beta-Peptides*/metabolism , Zinc*/chemistry , Peptide Fragments*/chemistry , Peptide Fragments*/metabolism, Humans ; Cell Line, Tumor ; Alzheimer Disease/metabolism ; Cell Survival/drug effects

المؤلفون: Rodina N; Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Institute of Structural Biology (STB), Ingolstädter Landstr. 1, Neuherberg 85764, Germany., Hornung S; Division of Peptide Biochemistry, TUM School of Life Sciences, Technical University of Munich, Emil-Erlenmeyer-Forum 5, Freising 85354, Germany., Sarkar R; Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Institute of Structural Biology (STB), Ingolstädter Landstr. 1, Neuherberg 85764, Germany., Suladze S, Peters C, Schmid PWN, Niu Z; School of Pharmacy, Henan University, Kaifeng, Henan 475004, China., Haslbeck M, Buchner J, Kapurniotu A; Division of Peptide Biochemistry, TUM School of Life Sciences, Technical University of Munich, Emil-Erlenmeyer-Forum 5, Freising 85354, Germany., Reif B; Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Institute of Structural Biology (STB), Ingolstädter Landstr. 1, Neuherberg 85764, Germany.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2024 Jul 17; Vol. 146 (28), pp. 19077-19087. Date of Electronic Publication: 2024 Jul 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides*/chemistry , Amyloid beta-Peptides*/metabolism , Alzheimer Disease*/metabolism , Alzheimer Disease*/pathology , alpha-Crystallin B Chain*/chemistry , alpha-Crystallin B Chain*/metabolism , alpha-Crystallin B Chain*/genetics, Humans ; Peptide Fragments/chemistry ; Peptide Fragments/metabolism ; Peptide Fragments/genetics ; Amyloid/chemistry ; Amyloid/metabolism

المؤلفون: Chen J; College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China., Liu Q; College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China., Fu Y; College of Chemistry and Chemical Engineering, Hunan University, Changsha 410083, P. R. China., Xiang J; College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China.

المصدر: Analytical chemistry [Anal Chem] 2024 Jul 16; Vol. 96 (28), pp. 11397-11403. Date of Electronic Publication: 2024 Jun 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides*/analysis , Amyloid beta-Peptides*/blood , Amyloid beta-Peptides*/chemistry , DNA*/chemistry, Humans ; Nanostructures/chemistry ; Particle Size ; Electrochemical Techniques/methods ; Alzheimer Disease/diagnosis ; Alzheimer Disease/metabolism ; Alzheimer Disease/blood ; Biosensing Techniques/methods ; Solubility ; Aptamers, Nucleotide/chemistry ; Molecular Weight

المؤلفون: Tang Y; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China., Wang Y; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China., Gao Z; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China., Li J; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China., Zhang L; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China., Shi H; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China., Dong J; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China., Song S; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China., Qian C; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Science, School of Pharmacy, China Pharmaceutical University, Jiangsu, Nanjing, 210009, P.R. China.

المصدر: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Jul 16; Vol. 30 (40), pp. e202400870. Date of Electronic Publication: 2024 Jun 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

مواضيع طبية MeSH: Microglia*/metabolism , Mitochondria*/metabolism , Mitochondria*/drug effects , Amyloid beta-Peptides*/metabolism , Amyloid beta-Peptides*/chemistry , Phagocytosis* , Alzheimer Disease*/metabolism , Alzheimer Disease*/drug therapy , Alzheimer Disease*/pathology , Molecular Docking Simulation* , Amyloid beta-Protein Precursor*/metabolism, Humans ; Animals ; Mice ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/chemistry

المؤلفون: Zhang W; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Smith N; Department of Biological Sciences, Rensselaer Polytechnic Institute, NY 12180, USA., Zhou Y; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA; Department of Biological Sciences, Florida International University, Miami, FL 33199, USA., McGee CM; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Bartoli M; Department of Applied Science and Technology, Politecnico di Torino, Italy; Center for Sustainable Future Technologies (CSFT), Istituto Italiano di Technologia (IIT), Via Livorno 60, 10144 Turin, Italy., Fu S; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Chen J; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Domena JB; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Joji A; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Burr H; Department of Biological Sciences, Rensselaer Polytechnic Institute, NY 12180, USA., Lv G; Department of Biochemistry, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Cilingir EK; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Bedendo S; Department of Applied Science and Technology, Politecnico di Torino, Italy., Claure ML; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Tagliaferro A; Department of Applied Science and Technology, Politecnico di Torino, Italy., Eliezer D; Department of Biochemistry, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Veliz EA; Department of Natural Sciences, Miami Dade Collage, Miami, FL 33132, USA., Zhang F; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA., Wang C; Department of Biological Sciences, Rensselaer Polytechnic Institute, NY 12180, USA. Electronic address: wangc5@rpi.edu., Leblanc RM; Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA. Electronic address: rml@miami.edu.

المصدر: Acta biomaterialia [Acta Biomater] 2024 Jul 15; Vol. 183, pp. 341-355. Date of Electronic Publication: 2024 Jun 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism , Alzheimer Disease*/pathology , Amyloid beta-Peptides*/metabolism , Amyloid beta-Peptides*/antagonists & inhibitors , Carbon*/chemistry , tau Proteins*/metabolism , tau Proteins*/antagonists & inhibitors , Zebrafish*, Animals ; Humans ; Congo Red/chemistry ; Blood-Brain Barrier/metabolism ; Blood-Brain Barrier/drug effects ; Protein Aggregates/drug effects ; Quantum Dots/chemistry

المؤلفون: Xu F; Department of Chemistry and Biochemical Engineering, Graduate School of Science and Engineering, Yamagata University, Yonezawa, Yamagata 992-8510, Japan., Takiguchi Y; Department of Chemistry and Biochemical Engineering, Graduate School of Science and Engineering, Yamagata University, Yonezawa, Yamagata 992-8510, Japan., Makabe K; Department of Chemistry and Biochemical Engineering, Graduate School of Science and Engineering, Yamagata University, Yonezawa, Yamagata 992-8510, Japan., Konno H; Department of Chemistry and Biochemical Engineering, Graduate School of Science and Engineering, Yamagata University, Yonezawa, Yamagata 992-8510, Japan. Electronic address: konno@yz.yamagata-u.ac.jp.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Jul 15; Vol. 107, pp. 129788. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides*/antagonists & inhibitors , Amyloid beta-Peptides*/metabolism , Catecholamines*/metabolism , Molecular Docking Simulation* , Protein Aggregates*/drug effects, Humans ; Structure-Activity Relationship ; Molecular Structure ; Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism ; Dose-Response Relationship, Drug

المؤلفون: Foret MK; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada., Orciani C; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada., Welikovitch LA; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada., Huang C; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada., Cuello AC; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada. claudio.cuello@mcgill.ca.; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada. claudio.cuello@mcgill.ca.; Department of Anatomy and Cell Biology, McGill University, Montreal, QC, Canada. claudio.cuello@mcgill.ca.; Department of Pharmacology, Oxford University, Oxford, UK. claudio.cuello@mcgill.ca., Do Carmo S; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada. sonia.docarmo@mcgill.ca.

المصدر: Communications biology [Commun Biol] 2024 Jul 14; Vol. 7 (1), pp. 861. Date of Electronic Publication: 2024 Jul 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

مواضيع طبية MeSH: Oxidative Stress* , Alzheimer Disease*/metabolism , Alzheimer Disease*/genetics , Alzheimer Disease*/pathology , Hippocampus*/metabolism , Hippocampus*/pathology , Neurons*/metabolism , DNA Damage* , Amyloid beta-Peptides*/metabolism , Amyloid beta-Peptides*/genetics , Rats, Transgenic* , Disease Models, Animal*, Animals ; Rats ; Male ; Neuronal Plasticity

المؤلفون: Li J; College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China., Hu Y; Psychology, Beijing Normal University, Beijing, China., Xu Y; College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China., Feng X; Biomedical Engineering, University of Virginia, Charlottesville, VA, US., Meyer CH; Biomedical Engineering, University of Virginia, Charlottesville, VA, US., Dai W; Department of Computer Science, State University of New York at Binghamton, Binghamton, NY, US., Zhao L; College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China. lz5bf@virginia.edu.

مؤلفون مشاركون: Alzheimer’s Disease Neuroimaging Initiative

المصدر: Fluids and barriers of the CNS [Fluids Barriers CNS] 2024 Jul 12; Vol. 21 (1), pp. 56. Date of Electronic Publication: 2024 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118 (Electronic) Linking ISSN: 20458118 NLM ISO Abbreviation: Fluids Barriers CNS Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/metabolism , Alzheimer Disease*/cerebrospinal fluid , tau Proteins*/cerebrospinal fluid , tau Proteins*/metabolism , Choroid Plexus*/diagnostic imaging , Choroid Plexus*/metabolism , Amyloid beta-Peptides*/cerebrospinal fluid , Amyloid beta-Peptides*/metabolism, Humans ; Male ; Female ; Aged ; Supervised Machine Learning ; Biomarkers/cerebrospinal fluid ; Biomarkers/metabolism ; Magnetic Resonance Imaging/methods ; Image Processing, Computer-Assisted/methods ; Middle Aged ; Aged, 80 and over

المؤلفون: Agnello L; Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, Department of Biomedicine, Neurosciences, and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy., Giglio RV; Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, Department of Biomedicine, Neurosciences, and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy.; Department of Laboratory Medicine, University Hospital 'P. Giaccone', Palermo, Italy., Del Ben F; Immunopathology and Cancer Biomarkers, Centro di Riferimento Oncologico di Aviano (CRO)-IRCCS, Aviano, Italy., Piccoli T; Neurology Unit, Department of Biomedicine, Neuroscience, and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy., Colletti T; Department of Biological, Chemical, and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Palermo, Italy., Scazzone C; Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, Department of Biomedicine, Neurosciences, and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy., Lo Sasso B; Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, Department of Biomedicine, Neurosciences, and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy.; Department of Laboratory Medicine, University Hospital 'P. Giaccone', Palermo, Italy., Ciaccio AM; Internal Medicine and Medical Specialties 'G. D'Alessandro', Department of Health Promotion, Maternal, and Infant Care, University of Palermo, Palermo, Italy., Gambino CM; Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, Department of Biomedicine, Neurosciences, and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy.; Department of Laboratory Medicine, University Hospital 'P. Giaccone', Palermo, Italy., Salemi G; Neurology Unit, Department of Biomedicine, Neuroscience, and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy., Ciaccio M; Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, Department of Biomedicine, Neurosciences, and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy. marcello.ciaccio@unipa.it.; Department of Laboratory Medicine, University Hospital 'P. Giaccone', Palermo, Italy. marcello.ciaccio@unipa.it.

المصدر: Scientific reports [Sci Rep] 2024 Jul 12; Vol. 14 (1), pp. 16084. Date of Electronic Publication: 2024 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/blood , Alzheimer Disease*/diagnosis , Alzheimer Disease*/cerebrospinal fluid , Alzheimer Disease*/metabolism , Saliva*/metabolism , Saliva*/chemistry , Biomarkers*/blood , Biomarkers*/cerebrospinal fluid , Amyloid beta-Peptides*/cerebrospinal fluid , Amyloid beta-Peptides*/blood , Amyloid beta-Peptides*/analysis , tau Proteins*/cerebrospinal fluid , tau Proteins*/blood , tau Proteins*/analysis, Humans ; Female ; Male ; Aged ; Middle Aged ; Peptide Fragments/cerebrospinal fluid ; Peptide Fragments/blood ; Peptide Fragments/analysis ; Luminescent Measurements/methods ; Aged, 80 and over