نتائج البحث - "and Alfredo Paio"

1

Corrections to 'An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer'

المؤلفون: Annunziata D’Ercole, Lorenzo Pacini, Giuseppina Sabatino, Matteo Zini, Lorenzo Milli, Francesca Nuti, Arianna Ribecai, Alfredo Paio, Paolo Rovero, Anna Maria Papini

المصدر: Organic Process Research & Development. 26:2540-2540

مصطلحات موضوعية: Organic Chemistry, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c680b22d62d2758b243be1c6ad337a45
https://doi.org/10.1021/acs.oprd.2c00224

Find this issue from the American Chemical Society

2

An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer

المؤلفون: Paolo Rovero, Alfredo Paio, Annunziata D’Ercole, Matteo Zini, Francesca Nuti, L. Pacini, Anna Maria Papini, Arianna Ribecai, Giuseppina Sabatino

المصدر: Organic process research & development 25 (2021): 2754–2771. doi:10.1021/acs.oprd.1c00368
info:cnr-pdr/source/autori:D'Ercole, Annunziata; Pacini, Lorenzo; Sabatino, Giuseppina; Zini, Matteo; Nuti, Francesca; Ribecai, Arianna; Paio, Alfredo; Rovero, Paolo; Papini, Anna Maria/titolo:An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer/doi:10.1021%2Facs.oprd.1c00368/rivista:Organic process research & development/anno:2021/pagina_da:2754/pagina_a:2771/intervallo_pagine:2754–2771/volume:25

مصطلحات موضوعية: chemistry.chemical_classification, Materials science, Chromatography, technology transfer, Organic Chemistry, multigram-scale microwave-assisted peptide synthesis, Peptide, generic peptide drug, Microwave assisted, peptide production scale-up, peptide production pilot plant, chemistry, Phase (matter), generic peptide drug, peptide production scale-up, multigram-scale microwave-assisted peptide synthesis, technology transfer, peptide production pilot plant, Eptifibatide, medicine, Physical and Theoretical Chemistry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29c2a766b49246c4ffd343dfd85a016
https://publications.cnr.it/doc/464122

3

An Optimized Scalable Fully Automated Solid-Phase Microwave-Assisted cGMP-Ready Process for the Preparation of Eptifibatide

المؤلفون: L. Pacini, Annunziata D’Ercole, Matteo Zini, Alfredo Paio, Paolo Rovero, Anna Maria Papini, Giuseppina Sabatino, Arianna Ribecai

المصدر: Organic process research & development (2021). doi:10.1021/acs.oprd.0c00490
info:cnr-pdr/source/autori:Papini, Anna Maria; Sabatino, Giuseppina; D'Ercole, Annunziata; Pacini, Lorenzo; Zini, Matteo; Ribecai, Arianna; Paio, Alfredo; Rovero, Paolo/titolo:An optimized scalable fully automated solid-phase microwave-assisted cGMP-ready process for the preparation of eptifibatide/doi:10.1021%2Facs.oprd.0c00490/rivista:Organic process research & development/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume

مصطلحات موضوعية: Materials science, Scale-up, Nanotechnology, active pharmaceutical ingredient, peptide, scale-up, oxidation, automated on-resin disulfide bond formation, off-resin disulfide bond formation, single reactor solid-phase synthesis, 010402 general chemistry, 01 natural sciences, Microwave assisted, chemistry.chemical_compound, Phase (matter), Oxidation, medicine, Peptide synthesis, Physical and Theoretical Chemistry, Active ingredient, 010405 organic chemistry, Organic Chemistry, Off-resin disulfide bond formation, 0104 chemical sciences, Fully automated, chemistry, Scientific method, Peptide, Single reactor solid-phase synthesis, Scalability, Eptifibatide, Active pharmaceutical ingredient, Automated on-resin disulfide bond formation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c4b0fe2aba17e3983bfb82d507cdb0
http://hdl.handle.net/2158/1219739

4

Synthesis and Structure–Activity Relationships of α-Amino-γ-lactone Ketolides: A Novel Class of Macrolide Antibiotics

المؤلفون: Daniele Donati, Stefano Biondi, Alfredo Paio, Stjepan Mutak, Sergio Lociuro, Elisa Piga, Francesca Cardullo, Dražen Pavlović, Daniele Andreotti

المصدر: ACS Medicinal Chemistry Letters. 5:1133-1137

مصطلحات موضوعية: chemistry.chemical_classification, medicine.drug_class, Stereochemistry, Organic Chemistry, Telithromycin, Erythromycin, Biology, Biochemistry, In vitro, Macrolide Antibiotics, Microbiology, chemistry, Clarithromycin, Drug Discovery, medicine, Antibacterial activity, Ketolide, Lactone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8c82745e0260869ef5d53f6e44524e
https://doi.org/10.1021/ml500279k

Find this issue from the American Chemical Society

5

Rapid Access to 1-Benzyl 2-Substituted Piperazines: Application to the Synthesis of 1-Benzyl-2-difluoromethyl-Piperazine

المؤلفون: Daniele Donati, Francesca Cardullo, Carmela Napolitano, Stefano Manfredini, Alfredo Paio, Manuela Borriello

المصدر: Synthetic Communications. 41:2031-2035

مصطلحات موضوعية: Piperazine, chemistry.chemical_compound, chemistry, Organic Chemistry, Rapid access, Organic chemistry, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9d03e38c7789a8fa1ea9c58b8881b3e2
https://doi.org/10.1080/00397911.2010.491171

PDF full text from Publisher

6

Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]octane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

المؤلفون: Daniele Andreotti, Roberto Profeta, Alfredo Paio, Simone Spada, Francesco Ferroni, Jens Klein

المصدر: Tetrahedron Letters. 51:5521-5524

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Stereochemistry, Aryl, Organic Chemistry, Drug Discovery, Organic chemistry, Biochemistry, Octane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9a9af09b68927810407ff57c9b2f1aa6
https://doi.org/10.1016/j.tetlet.2010.07.145

View record from ScienceDirect

7

Synthesis of 3-azabicyclo[4.1.0]heptane-1-carboxylic acid

المؤلفون: Daniele Donati, Manuela Borriello, Carmela Napolitano, Francesca Cardullo, Alfredo Paio, Stefano Manfredini

المصدر: Tetrahedron. 66:5492-5497

مصطلحات موضوعية: chemistry.chemical_classification, Heptane, Bicyclic molecule, Intramolecular reaction, Stereochemistry, Carboxylic acid, Organic Chemistry, Biochemistry, Chemical synthesis, chemistry.chemical_compound, chemistry, Drug Discovery, Lactam, Chemoselectivity, Imide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a1ac1b673e036f9e01973adaa531100
https://doi.org/10.1016/j.tet.2010.05.006

View record from ScienceDirect

8

Polymer-Supported Haloarene Chromium Dicarbonyl Isonitrile Complexes: A Study of Their Synthesis and Reactivity

المؤلفون: Giovanna Zinzalla, Carla Marchioro, Laura Casiraghi, Stefano Maiorana, Clara Baldoli, Elisabetta de Magistris, Pierfausto Seneci, and Alfredo Paio, Emanuela Licandro

المصدر: Journal of Combinatorial Chemistry. 5:809-813

مصطلحات موضوعية: Polymers, Ligand, chemistry.chemical_element, General Chemistry, Dichlorobenzene, Chromium, chemistry.chemical_compound, chemistry, Nucleophile, Chromium Compounds, Polymer chemistry, Technology, Pharmaceutical, Organic chemistry, Reactivity (chemistry), Polystyrene, Polymer supported

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cefdddcaaabc2d9c1f6606b85b493db9
https://doi.org/10.1021/cc0340123

Find this issue from the American Chemical Society

9

A new analytical method for anchoring quantification of amines on resin support

المؤلفون: Gianna Reginato, Pierfausto Seneci, Sylvie Gehanne, Elena Grandini, Alfredo Paio

المصدر: Tetrahedron letters 44 (2003): 1867–1870. doi:10.1016/S0040-4039(03)00090-X
info:cnr-pdr/source/autori:Paio, Alfredo; Gehanne, Sylvie; Grandini, Elena; Reginato, Gianna; Seneci, Pierfausto/titolo:A new analytical method for anchoring quantification of amines on resin support/doi:10.1016%2FS0040-4039(03)00090-X/rivista:Tetrahedron letters/anno:2003/pagina_da:1867/pagina_a:1870/intervallo_pagine:1867–1870/volume:44

مصطلحات موضوعية: Carbamate, medicine.medical_treatment, amines, Organic Chemistry, Anchoring, Chromophore, Biochemistry, loading, chemistry.chemical_compound, chemistry, Yield (chemistry), Drug Discovery, solid phase, medicine, Organic chemistry, Polystyrene, Linker

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6972436ee7da4dd8270dcee08d6d78
https://doi.org/10.1016/s0040-4039(03)00090-x

View record from ScienceDirect

10

Solid-phase versus solution synthesis of asymmetrically disubstituted furazano[3,4-b]pyrazines

المؤلفون: Sophie Huss, Araceli Mallo, Alfredo Paio, Jose M. Bueno, Paola Zarantonello, Silvestre Garcı́a-Ochoa, Fabrizio Micheli, Elisa Piga, Esther Fernández

المصدر: Tetrahedron Letters. 43:4741-4745

مصطلحات موضوعية: Pyrazine, Chemistry, Organic Chemistry, Chlorine atom, Solution chemistry, Solution synthesis, Biochemistry, Combinatorial chemistry, chemistry.chemical_compound, Nucleophile, Phase (matter), Drug Discovery, Organic chemistry, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fb427161a868d885141adabef20b935f
https://doi.org/10.1016/s0040-4039(02)00913-9

View record from ScienceDirect

تنقيح النتائج