المؤلفون: Ikari J; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan junikari@chiba-u.jp., Katsumata M; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Urano A; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Imamoto T; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Suzuki Y; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Nishiyama A; Department of Radiology, Tsudanuma Central General Hospital, Narashino, Chiba, Japan., Yokota H; Department of Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Ono K; Medical Imaging R&D Center, Healthcare Business Headquarters, Konica Minolta Inc, Chiyoda-ku, Tokyo, Japan., Okamoto K; Medical Imaging R&D Center, Healthcare Business Headquarters, Konica Minolta Inc, Chiyoda-ku, Tokyo, Japan., Abe E; Division of laboratory medicine, Chiba University Hospital, Chiba, Chiba, Japan., Kamata T; Division of laboratory medicine, Chiba University Hospital, Chiba, Chiba, Japan., Fujii S; Department of Radiology, Chiba University Hospital, Chiba, Chiba, Japan., Okumura K; Department of Radiology, Chiba University Hospital, Chiba, Chiba, Japan., Ota J; Department of Radiology, Chiba University Hospital, Chiba, Chiba, Japan., Suzuki E; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Kawata N; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Ozawa Y; Biostatistics Section, Clinical Research Center, Chiba University Hospital, Chiba, Chiba, Japan., Masuda Y; Department of Radiology, Chiba University Hospital, Chiba, Chiba, Japan., Matsushita K; Division of laboratory medicine, Chiba University Hospital, Chiba, Chiba, Japan., Sakao S; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan.; Department of Respiratory Medicine, international university of health and welfare, Narita, Chiba, Japan., Uno T; Department of Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Tatsumi K; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan., Suzuki T; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan.

المصدر: BMJ open respiratory research [BMJ Open Respir Res] 2024 Aug 05; Vol. 11 (1). Date of Electronic Publication: 2024 Aug 05.

نوع المنشور: Journal Article; Clinical Trial Protocol; Comparative Study

بيانات الدورية: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE

مواضيع طبية MeSH: Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/diagnostic imaging , Pulmonary Disease, Chronic Obstructive*/physiopathology , Tiotropium Bromide*/administration & dosage , Tiotropium Bromide*/therapeutic use , Bronchodilator Agents*/therapeutic use , Bronchodilator Agents*/administration & dosage , Benzoxazines*/therapeutic use , Benzoxazines*/administration & dosage , Drug Combinations*, Humans ; Prospective Studies ; Aged ; Middle Aged ; Male ; Aged, 80 and over ; Female ; Adult ; Radiography, Thoracic ; Forced Expiratory Volume/drug effects ; Lung/diagnostic imaging ; Lung/physiopathology ; Lung/drug effects

المؤلفون: Barroso S; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain., Guitart-Mampel M; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain., García-García FJ; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain., Cantó-Santos J; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain., Valls-Roca L; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain., Andújar-Sánchez F; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain., Vilaseca-Capel A; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain., Tobías E; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain., Arias-Dimas A; Department of Clinical Biochemistry, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, 08950 Barcelona, Spain., Quesada-López T; Biochemistry and Molecular Biomedicine Department, Biomedicine Institute (IBUB), University of Barcelona (UB), 08014 Barcelona, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain., Artuch R; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain.; Department of Clinical Biochemistry, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, 08950 Barcelona, Spain., Villarroya F; Biochemistry and Molecular Biomedicine Department, Biomedicine Institute (IBUB), University of Barcelona (UB), 08014 Barcelona, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain., Giralt M; Biochemistry and Molecular Biomedicine Department, Biomedicine Institute (IBUB), University of Barcelona (UB), 08014 Barcelona, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain., Martínez E; Infectious Diseases Department, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBER of Infectious Diseases (CIBERINFEC), Carlos III Health Institute, 28029 Madrid, Spain., Lozano E; Department of Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona (UB), 08028 Barcelona, Spain., Garrabou G; Inherited Metabolic Diseases and Muscular Disorders Research Lab, Cellex-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine and Health Sciences, University of Barcelona (UB), 08036 Barcelona, Spain.; Department of Internal Medicine, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.; CIBERER-Spanish Biomedical Research Centre in Rare Diseases, Carlos III Health Institute, 28029 Madrid, Spain.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 01; Vol. 25 (15). Date of Electronic Publication: 2024 Aug 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: HIV Infections*/drug therapy , HIV Infections*/metabolism , Mitochondria*/metabolism , Mitochondria*/drug effects , Alkynes* , Benzoxazines*/therapeutic use , Benzoxazines*/pharmacology , Anti-HIV Agents*/therapeutic use , Anti-HIV Agents*/adverse effects , Cyclopropanes*/therapeutic use , Tenofovir*/therapeutic use , Emtricitabine*/therapeutic use , DNA, Mitochondrial*/metabolism, Humans ; Male ; Female ; Adult ; Middle Aged ; Inflammation

المؤلفون: Rao W; HEC Research and Development Center, HEC Pharm Group, Dongguan, China.; State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd, Dongguan, China., Zhang C; HEC Research and Development Center, HEC Pharm Group, Dongguan, China.; State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd, Dongguan, China., Luan B; HEC Research and Development Center, HEC Pharm Group, Dongguan, China.; State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd, Dongguan, China., Wang Z; HEC Research and Development Center, HEC Pharm Group, Dongguan, China.; State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd, Dongguan, China., Qiu M; HEC Research and Development Center, HEC Pharm Group, Dongguan, China.; State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd, Dongguan, China., Cai S; HEC Research and Development Center, HEC Pharm Group, Dongguan, China.; State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd, Dongguan, China.

المصدر: Chirality [Chirality] 2024 Aug; Vol. 36 (8), pp. e23704.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 8914261 Publication Model: Print Cited Medium: Internet ISSN: 1520-636X (Electronic) Linking ISSN: 08990042 NLM ISO Abbreviation: Chirality Subsets: MEDLINE

مواضيع طبية MeSH: Benzoxazines*/chemistry , Benzoxazines*/analysis , Thermodynamics*, Stereoisomerism ; Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Limit of Detection

المؤلفون: Guo L; Department of Infection, Guiyang Public Health Clinical Center, Guiyang, China., Fu Y; Department of Infection, Guiyang Public Health Clinical Center, Guiyang, China., Xie X; Department of Infection, Guiyang Public Health Clinical Center, Guiyang, China., Yan W; Department of Pharmacy, Guiyang Maternal and Child Health Care Hospital, Guiyang, China., Long H; Department of Infection, Guiyang Public Health Clinical Center, Guiyang, China.

المصدر: AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2024 Aug; Vol. 40 (8), pp. 482-488. Date of Electronic Publication: 2024 Jun 03.

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 8709376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-8405 (Electronic) Linking ISSN: 08892229 NLM ISO Abbreviation: AIDS Res Hum Retroviruses Subsets: MEDLINE

مواضيع طبية MeSH: HIV Infections*/drug therapy , Benzoxazines*/therapeutic use , Benzoxazines*/adverse effects , Cyclopropanes*/therapeutic use , Alkynes*/therapeutic use , Anti-HIV Agents*/therapeutic use , Anti-HIV Agents*/adverse effects, Humans ; Male ; Female ; China ; Adult ; Retrospective Studies ; Middle Aged ; CD4 Lymphocyte Count ; Viral Load/drug effects ; Treatment Outcome ; HIV-1/drug effects ; Reverse Transcriptase Inhibitors/therapeutic use ; Reverse Transcriptase Inhibitors/adverse effects ; RNA, Viral/blood ; Antiretroviral Therapy, Highly Active/adverse effects ; Antiretroviral Therapy, Highly Active/methods

المؤلفون: Pettersson Bergstrand M; Department of Clinical Pharmacology, Karolinska University Hospital, Stockholm, Sweden.; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden., Soeria-Atmadja S; Department of Pediatrics, Karolinska University Hospital, Stockholm, Sweden; and.; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden., Barclay V; Department of Clinical Pharmacology, Karolinska University Hospital, Stockholm, Sweden.; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden., Tolic J; Department of Clinical Pharmacology, Karolinska University Hospital, Stockholm, Sweden., Navér L; Department of Pediatrics, Karolinska University Hospital, Stockholm, Sweden; and.; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden., Gustafsson LL; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden., Pohanka A; Department of Clinical Pharmacology, Karolinska University Hospital, Stockholm, Sweden.; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.

المصدر: Therapeutic drug monitoring [Ther Drug Monit] 2024 Aug 01; Vol. 46 (4), pp. 468-476. Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7909660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-3694 (Electronic) Linking ISSN: 01634356 NLM ISO Abbreviation: Ther Drug Monit Subsets: MEDLINE

مواضيع طبية MeSH: Cyclopropanes* , Benzoxazines*/blood , Benzoxazines*/pharmacokinetics , Alkynes* , Tandem Mass Spectrometry*/methods, Humans ; Chromatography, Liquid/methods ; Child ; Anti-HIV Agents/blood ; Anti-HIV Agents/pharmacokinetics ; Child, Preschool ; HIV Infections/drug therapy ; HIV Infections/blood ; Reproducibility of Results

المؤلفون: Funk NL; Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Laboratório de Nanocarreadores e Impressão 3D em Tecnologia Farmacêutica (Nano3D), Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK., Januskaite P; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK., Beck RCR; Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Laboratório de Nanocarreadores e Impressão 3D em Tecnologia Farmacêutica (Nano3D), Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil., Basit AW; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK; FABRX Artificial Intelligence, Carretera de Escairón, 14, Currelos (O Saviñao) CP 27543, Spain. Electronic address: a.basit@ucl.ac.uk., Goyanes A; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK; FABRX Artificial Intelligence, Carretera de Escairón, 14, Currelos (O Saviñao) CP 27543, Spain; Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, I+D Farma (GI-1645), Facultad de Farmacia, Instituto de Materiales (iMATUS) and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain. Electronic address: a.goyanes@fabrx.co.uk.

المصدر: International journal of pharmaceutics [Int J Pharm] 2024 Jul 20; Vol. 660, pp. 124299. Date of Electronic Publication: 2024 Jun 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Alkynes*/chemistry , Cyclopropanes* , Benzoxazines*/administration & dosage , Benzoxazines*/chemistry , Printing, Three-Dimensional* , Tablets*, Humans ; Anti-HIV Agents/administration & dosage ; Anti-HIV Agents/chemistry ; Solubility ; Enteral Nutrition/methods ; Child ; Excipients/chemistry ; Polymers/chemistry ; Intubation, Gastrointestinal/methods ; HIV Infections/drug therapy ; Drug Delivery Systems ; Drug Liberation ; Porosity

المؤلفون: Wang J; Department of Pharmacy, Phase I Clinical Trial Center, Xuanwu Hospital Capital Medical University, Beijing, People's Republic of China., Hu C; Department of Pharmacy, Phase I Clinical Trial Center, Xuanwu Hospital Capital Medical University, Beijing, People's Republic of China., Zhang L; Department of Pharmacy, Phase I Clinical Trial Center, Xuanwu Hospital Capital Medical University, Beijing, People's Republic of China.

المصدر: Drug design, development and therapy [Drug Des Devel Ther] 2024 Jul 19; Vol. 18, pp. 3113-3119. Date of Electronic Publication: 2024 Jul 19 (Print Publication: 2024).

نوع المنشور: Case Reports; Clinical Trial; Journal Article

بيانات الدورية: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

مواضيع طبية MeSH: Benzoxazines*/administration & dosage , Benzoxazines*/pharmacology , Benzoxazines*/pharmacokinetics , Cyclopropanes*/administration & dosage , Cyclopropanes*/pharmacology , Cyclopropanes*/pharmacokinetics , Alkynes* , Healthy Volunteers*, Humans ; Adult ; Male ; Female ; Young Adult ; Administration, Oral ; Middle Aged ; Drug Interactions ; Cytochrome P-450 CYP3A Inducers/pharmacology ; Cytochrome P-450 CYP3A Inducers/administration & dosage ; Area Under Curve ; Dose-Response Relationship, Drug

المؤلفون: Sawry S; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa., Ayalew K; Division of Global HIV and TB, Centers for Disease Control and Prevention (CDC), Pretoria, South Africa., Maimela G; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa., Briggs-Hagen M; Division of Global HIV and TB, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA., van Wyk-Heath M; Division of Global HIV and TB, Centers for Disease Control and Prevention (CDC), Pretoria, South Africa., Mthethwa S; Division of Global HIV and TB, Centers for Disease Control and Prevention (CDC), Pretoria, South Africa., Shai S; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa., Mngomezulu NN; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa., Tlhowe L; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa., Achere-Darko J; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa., Bedford J; Division of Global HIV and TB, Centers for Disease Control and Prevention (CDC), Pretoria, South Africa., Martin CE; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa., Fairlie L; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa., Imrie J; Wits RHI, University of the Witwatersrand, Johannesburg, South Africa.

المصدر: HIV medicine [HIV Med] 2024 Jul; Vol. 25 (7), pp. 826-839. Date of Electronic Publication: 2024 Mar 22.

نوع المنشور: Journal Article; Observational Study

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 100897392 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-1293 (Electronic) Linking ISSN: 14642662 NLM ISO Abbreviation: HIV Med Subsets: MEDLINE

مواضيع طبية MeSH: Weight Gain*/drug effects , HIV Infections*/drug therapy , Pyridones* , Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/adverse effects , Heterocyclic Compounds, 3-Ring*/administration & dosage , Oxazines*/therapeutic use , Benzoxazines*/therapeutic use , Benzoxazines*/adverse effects , Benzoxazines*/administration & dosage , Alkynes* , Cyclopropanes*, Humans ; Male ; Female ; Adult ; South Africa ; Retrospective Studies ; Middle Aged ; Piperazines ; Anti-HIV Agents/therapeutic use ; Anti-HIV Agents/adverse effects ; Longitudinal Studies ; Body Mass Index ; Lamivudine/therapeutic use ; Lamivudine/adverse effects ; Lamivudine/administration & dosage ; Tenofovir/therapeutic use ; Tenofovir/adverse effects ; Tenofovir/administration & dosage ; Emtricitabine/therapeutic use ; Emtricitabine/administration & dosage

المؤلفون: Huang G; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Jung A; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Li LX; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Do N; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Jung S; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Jeon Y; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Zuo D; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Thanh La M; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Van Manh N; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Blumberg PM; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea., Yoon H; College of Pharmacy, Chung-Ang University, Seoul 06974, South Korea., Lee Y; College of Pharmacy, Chung-Ang University, Seoul 06974, South Korea., Ann J; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea. Electronic address: jihuya@gmail.com., Lee J; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, South Korea. Electronic address: jeewoo@snu.ac.kr.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Jul 01; Vol. 106, pp. 129735. Date of Electronic Publication: 2024 Apr 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: TRPV Cation Channels*/antagonists & inhibitors , TRPV Cation Channels*/metabolism , Benzoxazines*/chemistry , Benzoxazines*/pharmacology , Benzoxazines*/chemical synthesis , Urea*/analogs & derivatives , Urea*/chemistry , Urea*/pharmacology , Urea*/chemical synthesis, Structure-Activity Relationship ; Humans ; Molecular Structure ; Animals ; Capsaicin/pharmacology ; Capsaicin/chemistry ; Drug Discovery ; Dose-Response Relationship, Drug

المؤلفون: Zhang P; Department of Ophthalmology, Huashan Hospital of Fudan University, Shanghai, China ; and., Qian Y; Department of Ophthalmology, Huashan Hospital of Fudan University, Shanghai, China ; and., Wang L; Department of Ophthalmology, Huashan Hospital of Fudan University, Shanghai, China ; and., Suo J; Department of Ophthalmology, Huashan Hospital of Fudan University, Shanghai, China ; and., Yin L; Department of Clinical Research Center, Shanghai Public Health Clinical Center, Fudan University., Wang Y; Department of Ophthalmology, Huashan Hospital of Fudan University, Shanghai, China ; and., Zhang L; Department of Clinical Research Center, Shanghai Public Health Clinical Center, Fudan University., Wang Z; Department of Ophthalmology, Huashan Hospital of Fudan University, Shanghai, China ; and.

المصدر: Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2024 Jul 01; Vol. 96 (3), pp. 299-303.

نوع المنشور: Journal Article; Observational Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins, Inc Country of Publication: United States NLM ID: 100892005 Publication Model: Print Cited Medium: Internet ISSN: 1944-7884 (Electronic) Linking ISSN: 15254135 NLM ISO Abbreviation: J Acquir Immune Defic Syndr Subsets: MEDLINE

مواضيع طبية MeSH: Benzoxazines*/therapeutic use , Benzoxazines*/pharmacokinetics , Alkynes* , Cyclopropanes* , HIV Infections*/drug therapy , HIV Infections*/virology , Viral Load* , HIV-1* , Anti-HIV Agents*/therapeutic use , Anti-HIV Agents*/pharmacokinetics, Humans ; Male ; Female ; Middle Aged ; Adult ; Retrospective Studies ; Vitreous Body/metabolism ; Vitreous Body/virology ; RNA, Viral/blood ; Vitrectomy