المؤلفون: Yu W; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.; Science Center for Future Foods, Jiangnan University, Wuxi, China., Jin K; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.; Science Center for Future Foods, Jiangnan University, Wuxi, China., Wang D; Science Center for Future Foods, Jiangnan University, Wuxi, China., Wang N; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China., Li Y; Science Center for Future Foods, Jiangnan University, Wuxi, China., Liu Y; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.; Science Center for Future Foods, Jiangnan University, Wuxi, China., Li J; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.; Science Center for Future Foods, Jiangnan University, Wuxi, China., Du G; Science Center for Future Foods, Jiangnan University, Wuxi, China., Lv X; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.; Science Center for Future Foods, Jiangnan University, Wuxi, China., Chen J; Science Center for Future Foods, Jiangnan University, Wuxi, China., Ledesma-Amaro R; Department of Bioengineering and Centre for Synthetic Biology, Imperial College London, London, UK., Liu L; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China. longliu@jiangnan.edu.cn.; Science Center for Future Foods, Jiangnan University, Wuxi, China. longliu@jiangnan.edu.cn.

المصدر: Nature communications [Nat Commun] 2024 Sep 12; Vol. 15 (1), pp. 7989. Date of Electronic Publication: 2024 Sep 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Bacillus subtilis*/metabolism , Bacillus subtilis*/genetics , Metabolic Engineering*/methods , Hexosamines*/biosynthesis , Hexosamines*/metabolism , Hexosamines*/chemistry , Bacterial Proteins*/metabolism , Bacterial Proteins*/genetics , Bacterial Proteins*/chemistry, Biosynthetic Pathways ; Protein Engineering/methods ; Protein Biosynthesis ; Trisaccharides/metabolism ; Trisaccharides/biosynthesis ; Trisaccharides/chemistry ; Liquid-Liquid Extraction/methods

المؤلفون: Qiu Y; College of Life Sciences, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China., Fu M; Heilongjiang Teacher Development College, Harbin, 150080, Heilongjiang, China., Zhang M; College of Life Sciences, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China., Qu B; College of Life Sciences, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China., Zhen Z; College of Life Sciences, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China. nneehhzz@126.com.

المصدر: In vitro cellular & developmental biology. Animal [In Vitro Cell Dev Biol Anim] 2024 Sep; Vol. 60 (8), pp. 949-958. Date of Electronic Publication: 2024 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 9418515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-706X (Electronic) Linking ISSN: 10712690 NLM ISO Abbreviation: In Vitro Cell Dev Biol Anim Subsets: MEDLINE

مواضيع طبية MeSH: Epithelial Cells*/metabolism , Epithelial Cells*/drug effects , Epithelial Cells*/cytology , Cell Proliferation*/drug effects , Signal Transduction*/drug effects , Mammary Glands, Animal*/cytology , Mammary Glands, Animal*/metabolism , Mammary Glands, Animal*/drug effects , Phosphatidylinositol 3-Kinases*/metabolism , DEAD-box RNA Helicases*/metabolism , DEAD-box RNA Helicases*/genetics , Milk Proteins*/metabolism , Milk Proteins*/biosynthesis , TOR Serine-Threonine Kinases*/metabolism, Animals ; Female ; Mice ; Cyclin D1/metabolism ; Cyclin D1/genetics ; Cattle ; Protein Biosynthesis/drug effects

المؤلفون: Ganesh RB; Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland., Maerkl SJ; Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.

المصدر: ACS synthetic biology [ACS Synth Biol] 2024 Aug 16; Vol. 13 (8), pp. 2555-2566. Date of Electronic Publication: 2024 Jul 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

مواضيع طبية MeSH: Protein Biosynthesis* , Cell-Free System*/metabolism , Transcription, Genetic*, Synthetic Biology/methods ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Recombinant Proteins/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/biosynthesis ; Dextrans/metabolism ; Dextrans/chemistry

المؤلفون: Jiang W; Biological Science Research Center, Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Southwest University, 400715 Chongqing, China; Key Laboratory for Germplasm Creation in Upper Reaches of the Yangtze River, Ministry of Agriculture and Rural Affairs, 400715 Chongqing, China; Engineering Laboratory of Sericultural and Functional Genome and Biotechnology, Development and Reform Commission, 400715 Chongqing, China., Guo K; Biological Science Research Center, Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Southwest University, 400715 Chongqing, China; Key Laboratory for Germplasm Creation in Upper Reaches of the Yangtze River, Ministry of Agriculture and Rural Affairs, 400715 Chongqing, China; Engineering Laboratory of Sericultural and Functional Genome and Biotechnology, Development and Reform Commission, 400715 Chongqing, China., Dong H; Key Laboratory for Germplasm Creation in Upper Reaches of the Yangtze River, Ministry of Agriculture and Rural Affairs, 400715 Chongqing, China; Engineering Laboratory of Sericultural and Functional Genome and Biotechnology, Development and Reform Commission, 400715 Chongqing, China., Zhang X; Biological Science Research Center, Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Southwest University, 400715 Chongqing, China; Key Laboratory for Germplasm Creation in Upper Reaches of the Yangtze River, Ministry of Agriculture and Rural Affairs, 400715 Chongqing, China; Engineering Laboratory of Sericultural and Functional Genome and Biotechnology, Development and Reform Commission, 400715 Chongqing, China., Guo Z; Biological Science Research Center, Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Southwest University, 400715 Chongqing, China., Duan J; Biological Science Research Center, Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Southwest University, 400715 Chongqing, China; Key Laboratory for Germplasm Creation in Upper Reaches of the Yangtze River, Ministry of Agriculture and Rural Affairs, 400715 Chongqing, China; Engineering Laboratory of Sericultural and Functional Genome and Biotechnology, Development and Reform Commission, 400715 Chongqing, China., Jing X; Biological Science Research Center, Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Southwest University, 400715 Chongqing, China; Key Laboratory for Germplasm Creation in Upper Reaches of the Yangtze River, Ministry of Agriculture and Rural Affairs, 400715 Chongqing, China; Engineering Laboratory of Sericultural and Functional Genome and Biotechnology, Development and Reform Commission, 400715 Chongqing, China., Xia Q; Key Laboratory for Germplasm Creation in Upper Reaches of the Yangtze River, Ministry of Agriculture and Rural Affairs, 400715 Chongqing, China; Engineering Laboratory of Sericultural and Functional Genome and Biotechnology, Development and Reform Commission, 400715 Chongqing, China., Zhao P; Biological Science Research Center, Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Southwest University, 400715 Chongqing, China; Key Laboratory for Germplasm Creation in Upper Reaches of the Yangtze River, Ministry of Agriculture and Rural Affairs, 400715 Chongqing, China; Engineering Laboratory of Sericultural and Functional Genome and Biotechnology, Development and Reform Commission, 400715 Chongqing, China. Electronic address: zhaop@swu.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Aug; Vol. 274 (Pt 2), pp. 133400. Date of Electronic Publication: 2024 Jun 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Bombyx*/genetics , Bombyx*/metabolism , Silk*/genetics , Silk*/biosynthesis , Silk*/metabolism , Insect Proteins*/genetics , Insect Proteins*/metabolism , Mutation*, Animals ; Larva/genetics ; Larva/metabolism ; Fibroins/genetics ; Fibroins/metabolism ; Proteomics/methods ; Protein Biosynthesis ; CRISPR-Cas Systems ; 3-Hydroxysteroid Dehydrogenases

المؤلفون: Sumi K; R&D Division, Meiji Co., Ltd., Hachiouji, Tokyo, Japan., Yamazaki K; Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Inage, Chiba, Japan., Nishii R; Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Inage, Chiba, Japan.; Biomedical Imaging Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Tokai National Education and Research System, Higashi-ku, Nagoya, Japan., Sakuda M; R&D Division, Meiji Co., Ltd., Hachiouji, Tokyo, Japan., Nakamura K; R&D Division, Meiji Co., Ltd., Hachiouji, Tokyo, Japan., Ashida K; R&D Division, Meiji Co., Ltd., Hachiouji, Tokyo, Japan., Tamura K; Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Inage, Chiba, Japan., Higashi T; Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Inage, Chiba, Japan.

المصدر: PloS one [PLoS One] 2024 Jul 30; Vol. 19 (7), pp. e0305620. Date of Electronic Publication: 2024 Jul 30 (Print Publication: 2024).

نوع المنشور: Journal Article; Clinical Trial

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Methionine*/metabolism , Positron Emission Tomography Computed Tomography*/methods , Muscle, Skeletal*/metabolism , Muscle, Skeletal*/diagnostic imaging , Muscle Proteins*/metabolism , Muscle Proteins*/biosynthesis, Humans ; Male ; Pilot Projects ; Adult ; Young Adult ; Carbon Radioisotopes ; Protein Biosynthesis

المؤلفون: Sawada A; Department of Physical Therapy, School of Rehabilitation Sciences, Health Sciences University of Hokkaido, Tobetsu 061-0293, Japan.; Graduate School of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan., Takagi R; School of Nursing and Rehabilitation Sciences, Showa University, Yokohama 226-8555, Japan., Takegaki J; Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan.; Faculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan., Fukao N; Graduate School of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan., Okumura K; Graduate School of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan., Fujita S; Faculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.

المصدر: Nutrients [Nutrients] 2024 Jul 23; Vol. 16 (15). Date of Electronic Publication: 2024 Jul 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Rats, Sprague-Dawley* , Gastrectomy* , Muscle, Skeletal*/metabolism , Muscle, Skeletal*/drug effects , Muscle Proteins*/biosynthesis , Muscle Proteins*/metabolism , Leucine*/administration & dosage , Leucine*/pharmacology , Milk*/chemistry, Animals ; Male ; Phosphorylation ; Rats ; Administration, Oral ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; Protein Biosynthesis/drug effects ; Intracellular Signaling Peptides and Proteins

المؤلفون: Pinckaers PJ; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., Domić J; Division of Human Nutrition & Health, Department of Agrotechnology and Food Sciences, Wageningen University, Wageningen, The Netherlands., Petrick HL; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., Holwerda AM; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., Trommelen J; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., Hendriks FK; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., Houben LH; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., Goessens JP; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., van Kranenburg JM; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., Senden JM; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., de Groot LC; Division of Human Nutrition & Health, Department of Agrotechnology and Food Sciences, Wageningen University, Wageningen, The Netherlands., Verdijk LB; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., Snijders T; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands., van Loon LJ; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands. Electronic address: l.vanloon@maastrichtuniversity.nl.

المصدر: The Journal of nutrition [J Nutr] 2024 Jul; Vol. 154 (7), pp. 2120-2132. Date of Electronic Publication: 2023 Nov 15.

نوع المنشور: Journal Article; Randomized Controlled Trial; Comparative Study

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0404243 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-6100 (Electronic) Linking ISSN: 00223166 NLM ISO Abbreviation: J Nutr Subsets: MEDLINE

مواضيع طبية MeSH: Muscle Proteins*/biosynthesis , Muscle Proteins*/metabolism , Cross-Over Studies* , Postprandial Period* , Diet, Vegan*, Humans ; Aged ; Female ; Male ; Aged, 80 and over ; Meals ; Dietary Proteins/administration & dosage ; Amino Acids/blood ; Amino Acids/metabolism ; Protein Biosynthesis

المؤلفون: Monteyne AJ; Department of Sport and Health Sciences, Nutritional Physiology Research Group, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom., West S; Department of Sport and Health Sciences, Nutritional Physiology Research Group, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom., Stephens FB; Department of Sport and Health Sciences, Nutritional Physiology Research Group, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom., Wall BT; Department of Sport and Health Sciences, Nutritional Physiology Research Group, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom. Electronic address: b.t.wall@exeter.ac.uk.

المصدر: The American journal of clinical nutrition [Am J Clin Nutr] 2024 Jul; Vol. 120 (1), pp. 7-16. Date of Electronic Publication: 2024 May 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0376027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-3207 (Electronic) Linking ISSN: 00029165 NLM ISO Abbreviation: Am J Clin Nutr Subsets: MEDLINE

مواضيع طبية MeSH: Leucine*/metabolism , Leucine*/administration & dosage , Muscle Proteins*/biosynthesis , Muscle Proteins*/metabolism , Postprandial Period*, Humans ; Diet ; Dietary Proteins/administration & dosage ; Dietary Proteins/metabolism ; Muscle, Skeletal/metabolism ; Protein Biosynthesis

المؤلفون: Lima KR; Physiology Research Group, Stress, Memory and Behavior Lab, Federal University of Pampa, Uruguaiana, RS, Brazil., Neves BSD; Physiology Research Group, Stress, Memory and Behavior Lab, Federal University of Pampa, Uruguaiana, RS, Brazil., Sigaran GJ; Physiology Research Group, Stress, Memory and Behavior Lab, Federal University of Pampa, Uruguaiana, RS, Brazil., Rosa ACSD; Physiology Research Group, Stress, Memory and Behavior Lab, Federal University of Pampa, Uruguaiana, RS, Brazil., Gomes GCM; Physiology Research Group, Stress, Memory and Behavior Lab, Federal University of Pampa, Uruguaiana, RS, Brazil., Gomes de Gomes M; Physiology Research Group, Stress, Memory and Behavior Lab, Federal University of Pampa, Uruguaiana, RS, Brazil; Center of Sciences, Tehcnologies and Health, Department of Health Sciences, Federal University of Santa Catarina, Araranguá, SC, Brazil., Mello-Carpes PB; Physiology Research Group, Stress, Memory and Behavior Lab, Federal University of Pampa, Uruguaiana, RS, Brazil. Electronic address: pamelacarpes@unipampa.edu.br.

المصدر: Neurochemistry international [Neurochem Int] 2024 Jun; Vol. 176, pp. 105740. Date of Electronic Publication: 2024 Apr 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9754 (Electronic) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE

مواضيع طبية MeSH: Physical Conditioning, Animal*/physiology , Hippocampus*/metabolism , Hippocampus*/drug effects , Anisomycin*/pharmacology , Rats, Wistar* , Brain-Derived Neurotrophic Factor*/metabolism , Brain-Derived Neurotrophic Factor*/biosynthesis , Amnesia*/metabolism , Amnesia*/prevention & control, Animals ; Male ; Rats ; Protein Synthesis Inhibitors/pharmacology ; Sirolimus/pharmacology ; Protein Biosynthesis/drug effects ; Protein Biosynthesis/physiology ; Memory Consolidation/drug effects ; Memory Consolidation/physiology ; Recognition, Psychology/drug effects ; Recognition, Psychology/physiology

المؤلفون: Lejeune C; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France. Electronic address: lejeune.clara@orange.fr., Cornu D; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France. Electronic address: david.cornu@i2bc.paris-saclay.fr., Sago L; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France. Electronic address: laila.sago@i2bc.paris-saclay.fr., Redeker V; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France; Institut Francois Jacob, Molecular Imaging Center (MIRCen), Laboratory of Neurodegenerative Diseases, Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Centre National de la Recherche Scientifique, Université Paris-Saclay, Fontenay-aux-Roses, France. Electronic address: virginie.redeker@cnrs.fr., Virolle MJ; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France. Electronic address: marie-joelle.virolle@i2bc.paris-saclay.fr.

المصدر: Research in microbiology [Res Microbiol] 2024 May-Jun; Vol. 175 (4), pp. 104177. Date of Electronic Publication: 2023 Dec 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: France NLM ID: 8907468 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1769-7123 (Electronic) Linking ISSN: 09232508 NLM ISO Abbreviation: Res Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Streptomyces coelicolor*/metabolism , Streptomyces coelicolor*/genetics , Streptomyces coelicolor*/growth & development , Anti-Bacterial Agents*/biosynthesis , Anti-Bacterial Agents*/metabolism , Bacterial Proteins*/genetics , Bacterial Proteins*/metabolism , Gene Expression Regulation, Bacterial* , Phosphates*/metabolism, Streptomyces lividans/metabolism ; Streptomyces lividans/genetics ; Proteome ; Ribosomal Proteins/metabolism ; Ribosomal Proteins/genetics ; Protein Biosynthesis ; Nitrogen/metabolism ; Proteomics ; Stress, Physiological