المؤلفون: Ng, Eunice Sze Yin, Kady, Nermin, Hu, Jane, Dave, Arpita, Jiang, Zhichun, Pei, Jacqueline, Gorin, Michael B, Matynia, Anna, Radu, Roxana A

المصدر: Cells. 11(21)

مصطلحات موضوعية: Eye Disease and Disorders of Vision, Neurosciences, Macular Degeneration, Neurodegenerative, Underpinning research, 1.1 Normal biological development and functioning, Eye, Humans, Stargardt Disease, Complement Membrane Attack Complex, Retinal Pigment Epithelium, ATP-Binding Cassette Transporters, Complement System Proteins, Cell Death, recessive Stargardt disease, retinal pigment epithelium, complement system, bisretinoid-lipofuscin, "disease-in-a-dish", retinoids, macular degeneration, ABCA4, “disease-in-a-dish”

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6zg9m1pg

المؤلفون: Jin Zhao, Hye Jin Kim, Diego Montenegro, Josh L. Dunaief, Janet R. Sparrow

المصدر: Frontiers in Ophthalmology, Vol 3 (2023)

مصطلحات موضوعية: iron, photoreceptor cells, retinal pigment epithelium, intravitreal injection, bisretinoid vitamin A, visual cycle, Medicine

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fopht.2023.1305864/full; https://doaj.org/toc/2674-0826

URL الوصول: https://doaj.org/article/a7610c600fc24bcd8b4c8261a335b3c0

المؤلفون: Hu, Jane, Pauer, Gayle J, Hagstrom, Stephanie A, Bok, Dean, DeBenedictis, Meghan J, Bonilha, Vera L, Hollyfield, Joe G, Radu, Roxana A

مصطلحات موضوعية: Biochemistry and Cell Biology, Medicinal and Biomolecular Chemistry, Chemical Sciences, Biological Sciences, Rare Diseases, Neurosciences, Eye Disease and Disorders of Vision, Neurodegenerative, Macular Degeneration, Aetiology, 2.1 Biological and endogenous factors, Eye, ATP-Binding Cassette Transporters, Animals, Humans, Mice, Retina, Retinal Pigment Epithelium, Stargardt Disease, Stargardt disease, Complement system, Retinal pigment epithelium, Membrane attack complex, Bisretinoid-lipofuscin, Age-related macular degeneration, Medical Biochemistry and Metabolomics, Pharmacology and Pharmaceutical Sciences, Biochemistry and cell biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/82c9x0sw

المؤلفون: Lenis, Tamara L, Hu, Jane, Ng, Sze Yin, Jiang, Zhichun, Sarfare, Shanta, Lloyd, Marcia B, Esposito, Nicholas J, Samuel, William, Jaworski, Cynthia, Bok, Dean, Finnemann, Silvia C, Radeke, Monte J, Redmond, T Michael, Travis, Gabriel H, Radu, Roxana A

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(47)

مصطلحات موضوعية: Macular Degeneration, Neurosciences, Rare Diseases, Genetics, Eye Disease and Disorders of Vision, Neurodegenerative, Aetiology, 2.1 Biological and endogenous factors, Eye, ATP-Binding Cassette Transporters, Animals, Cells, Cultured, Disease Models, Animal, Lipofuscin, Lysosomes, Mice, Mice, Inbred BALB C, Mice, Knockout, Phagocytosis, Photoreceptor Cells, Retina, Retinal Degeneration, Retinal Pigment Epithelium, Retinaldehyde, Rhodopsin, Stargardt Disease, c-Mer Tyrosine Kinase, Stargardt disease, retinal pigment epithelium, bisretinoid, lipofuscin, ABCA4

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/22h745hj

المؤلفون: Alexey N. Semenov, Eugene G. Maksimov, Anastasia M. Moysenovich, Marina A. Yakovleva, Georgy V. Tsoraev, Alla A. Ramonova, Evgeny A. Shirshin, Nikolai N. Sluchanko, Tatiana B. Feldman, Andrew B. Rubin, Mikhail P. Kirpichnikov, Mikhail A. Ostrovsky

المصدر: Antioxidants, Vol 12, Iss 2, p 413 (2023)

مصطلحات موضوعية: carotenoid-binding protein, zeaxanthin delivery, retinal pigment epithelium, lipofuscin, bisretinoid fluorophores, bisretinoid oxidation and degradation products, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/2/413; https://doaj.org/toc/2076-3921

URL الوصول: https://doaj.org/article/b23b1696131d4d6194be47326a1320f3

المؤلفون: Tatiana Feldman, Dmitriy Ostrovskiy, Marina Yakovleva, Alexander Dontsov, Sergey Borzenok, Mikhail Ostrovsky

المصدر: International Journal of Molecular Sciences, Vol 23, Iss 20, p 12234 (2022)

مصطلحات موضوعية: age-related macular degeneration, retinal pigment epithelium, lipofuscin granules, bisretinoid fluorophores, bisretinoid oxidation and degradation products, cytotoxicity, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/23/20/12234; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/2e526664f8c041a68c2964caf5dec76b

المؤلفون: Eunice Sze Yin Ng, Nermin Kady, Jane Hu, Arpita Dave, Zhichun Jiang, Jacqueline Pei, Michael B. Gorin, Anna Matynia, Roxana A. Radu

المصدر: Cells, Vol 11, Iss 21, p 3462 (2022)

مصطلحات موضوعية: recessive Stargardt disease (STGD1), retinal pigment epithelium (RPE), complement system, bisretinoid-lipofuscin, “disease-in-a-dish”, retinoids, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/21/3462; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/182604b4edaa4086ad8c400026a6bd81

المؤلفون: Ueda, Keiko^Aff12, Kim, Hye Jin^Aff12, Zhao, Jin^Aff12, Sparrow, Janet R.^{Aff12, Aff13}

المساهمون: COHEN, IRUN R., Series Editor^Aff1, LAJTHA, ABEL, Series Editor^Aff2, LAMBRIS, JOHN D., Series Editor^Aff3, PAOLETTI, RODOLFO, Series Editor^Aff4, REZAEI, NIMA, Series Editor^Aff5, Ash, John D., editor^Aff6, Anderson, Robert E., editor^Aff7, LaVail, Matthew M., editor^Aff8, Bowes Rickman, Catherine, editor^Aff9, Hollyfield, Joe G., editor^Aff10, Grimm, Christian, editor^Aff11

المصدر: Retinal Degenerative Diseases : Mechanisms and Experimental Therapy. 1074:395-401

المؤلفون: Marina Yakovleva, Alexander Dontsov, Natalia Trofimova, Natalia Sakina, Alexey Kononikhin, Arseny Aybush, Alexander Gulin, Tatiana Feldman, Mikhail Ostrovsky

المصدر: International Journal of Molecular Sciences, Vol 23, Iss 1, p 222 (2021)

مصطلحات موضوعية: age-related macular degeneration, retinal pigment epithelium, lipofuscin granules, bisretinoid fluorophores, bisretinoid oxidation products, cytotoxic carbonyls, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/23/1/222; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/2566171e0a7a4459bdfe0e8704e706e2

المؤلفون: Ueda, Keiko, Kim, Hye Jin, Zhao, Jin, Song, Ying, Dunaief, Joshua L., Sparrow, Janet R.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2018 May 01. 115(19), 4963-4968.

URL الوصول: https://www.jstor.org/stable/26509584