المؤلفون: Kleer JS; Laboratory of Clinical Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland.; Division of Internal Medicine, University Hospital, Basel, Switzerland., Skattum L; Department of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University, and Clinical Immunology and Transfusion Medicine, Region Skåne, Lund, Sweden., Dubler D; Laboratory of Clinical Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland., Fischer I; Division of Pathology, Cantonal Hospital Aarau, Aarau, Switzerland., Zgraggen A; Division of Rheumatology, Cantonal Hospital Aarau, Aarau, Switzerland., Mundwiler E; Division of Laboratory Medicine, Cantonal Hospital Aarau, Aarau, Switzerland., Kim MJ; Division of Nephrology , Cantonal Hospital Aarau, Aarau, Switzerland., Trendelenburg M; Laboratory of Clinical Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland.; Division of Internal Medicine, University Hospital, Basel, Switzerland.

المصدر: Frontiers in immunology [Front Immunol] 2024 Feb 26; Vol. 14, pp. 1257525. Date of Electronic Publication: 2024 Feb 26 (Print Publication: 2023).

نوع المنشور: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Complement C1s*/deficiency , Hereditary Complement Deficiency Diseases* , Lupus Erythematosus, Systemic*/complications , Lupus Erythematosus, Systemic*/diagnosis , Lupus Erythematosus, Systemic*/genetics , Lupus Nephritis*/diagnosis , Lupus Nephritis*/genetics, Adult ; Humans ; Male ; Codon, Nonsense ; Complement C1q/genetics ; Nucleotides ; Reinfection

SCR Disease Name: Complement Component C1s Deficiency

المؤلفون: Yuan D; The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China., Zheng Z; Dalian Medical University, Dalian, China., Shen C; Nanjing University of Chinese Medicine, Nanjing, China., Ye J; The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China. Electronic address: dingyinglinyejun@126.com., Zhu L; The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China. Electronic address: tzheartchina@126.com.

المصدر: Molecular immunology [Mol Immunol] 2024 Feb; Vol. 166, pp. 29-38. Date of Electronic Publication: 2024 Jan 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 7905289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9142 (Electronic) Linking ISSN: 01615890 NLM ISO Abbreviation: Mol Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis*/metabolism , Macrophages*/metabolism , Wnt Signaling Pathway* , Complement C1s*/metabolism, Humans ; beta Catenin/metabolism ; Foam Cells/metabolism

المؤلفون: Xu X; Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS., Herdendorf TJ; Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS., Duan H; Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS., Rohlik DL; Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC., Roy S; Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC., Zhou H; Department of Pharmacology, School of Medicine, St. Louis University, St. Louis, MO., Alkhateeb H; Department of Pharmacology, School of Medicine, St. Louis University, St. Louis, MO., Khandelwal S; Division of Hematology, Duke University Medical Center, Durham, NC., Zhou Q; Department of Chemistry, Kansas State University, Manhattan, KS., Li P; Department of Chemistry, Kansas State University, Manhattan, KS., Arepally GM; Division of Hematology, Duke University Medical Center, Durham, NC., Walker JK; Department of Pharmacology, School of Medicine, St. Louis University, St. Louis, MO.; Department of Chemistry, St. Louis University, St. Louis, MO., Garcia BL; Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC., Geisbrecht BV; Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS.

المصدر: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2024 Feb 15; Vol. 212 (4), pp. 689-701.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Complement Pathway, Classical* , Complement C1s*, Animals ; Sheep ; Peptide Hydrolases ; Complement C1/metabolism ; Endopeptidases ; Pyridines/pharmacology

المؤلفون: Simmons KT; Sanofi, Cambridge, MA, USA., Chan J; Former Sanofi Employee Affiliated with Sanofi at Time of Study., Hussain S; Former Sanofi Employee Affiliated with Sanofi at Time of Study., Rose EL; Former Sanofi Employee Affiliated with Sanofi at Time of Study., Markham K; Former Sanofi Employee Affiliated with Sanofi at Time of Study., Byun TS; Former Sanofi Employee Affiliated with Sanofi at Time of Study., Panicker S; Former Sanofi Employee Affiliated with Sanofi at Time of Study., Parry GC; Former Sanofi Employee Affiliated with Sanofi at Time of Study., Storek M; Sanofi, Cambridge, MA, USA. Electronic address: michael.storek@sanofi.com.

المصدر: Clinical immunology (Orlando, Fla.) [Clin Immunol] 2023 Jun; Vol. 251, pp. 109629. Date of Electronic Publication: 2023 May 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 100883537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-7035 (Electronic) Linking ISSN: 15216616 NLM ISO Abbreviation: Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Complement C1s*/metabolism , Anemia, Hemolytic, Autoimmune*, Humans ; Complement Activation ; Antibodies, Monoclonal, Humanized/pharmacology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Complement Inactivating Agents/therapeutic use ; Complement Pathway, Classical

المؤلفون: Thomas S; Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA., Schulz AM; Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA., Leong JM; Department of Molecular Biology and Microbiology, Tufts School of Medicine, Tufts University, Boston, Massachusetts, USA., Zeczycki TN; Department of Biochemistry & Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA., Garcia BL; Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA. Electronic address: garciabr18@ecu.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 May; Vol. 300 (5), pp. 107236. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Outer Membrane Proteins*/chemistry , Bacterial Outer Membrane Proteins*/genetics , Bacterial Outer Membrane Proteins*/metabolism , Borrelia burgdorferi*/immunology , Borrelia burgdorferi*/metabolism , Borrelia burgdorferi*/genetics , Complement Pathway, Classical*/immunology, Humans ; Complement C1r/metabolism ; Complement C1r/genetics ; Complement C1s/metabolism ; Complement C1s/genetics ; Complement C1s/chemistry ; Lipoproteins/metabolism ; Lipoproteins/genetics ; Lipoproteins/chemistry ; Lipoproteins/immunology ; Lyme Disease/genetics ; Lyme Disease/immunology ; Lyme Disease/microbiology ; Protein Binding

المؤلفون: Ikeda Z; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Kamei T; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Sasaki Y; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Reynolds M; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Sakai N; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Yoshikawa M; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Tawada M; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Morishita N; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Dougan DR; Structural Biology, Takeda Development Center Americas, Inc., San Diego, California 92121, United States., Chen CH; Structural Biology, Takeda Development Center Americas, Inc., San Diego, California 92121, United States., Levin I; Structural Biology, Takeda Development Center Americas, Inc., San Diego, California 92121, United States., Zou H; Structural Biology, Takeda Development Center Americas, Inc., San Diego, California 92121, United States., Kuno M; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Arimura N; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Kikukawa Y; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Kondo M; Discovery Biology, Discovery Science, Axcelead Drug Discovery Partners, Inc., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-0012, Japan., Tohyama K; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan., Sato K; Research, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.

المصدر: Journal of medicinal chemistry [J Med Chem] 2023 May 11; Vol. 66 (9), pp. 6354-6371. Date of Electronic Publication: 2023 Apr 25.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Complement C1s*/chemistry , Complement C1s*/metabolism , Complement Activation*, Humans ; Serine Endopeptidases/metabolism ; Brain/metabolism

المؤلفون: Lorvellec M; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Chouquet A; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Koch J; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Bally I; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Signor L; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Vigne J; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Dalonneau F; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Thielens NM; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Rabilloud T; Chemistry and Biology of Metals, University Grenoble Alpes, CNRS UMR 5249, CEA, IRIG-LCBM, Grenoble, France., Dalzon B; Chemistry and Biology of Metals, University Grenoble Alpes, CNRS UMR 5249, CEA, IRIG-LCBM, Grenoble, France., Rossi V; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France., Gaboriaud C; Institute of Structural Biology (IBS), University Grenoble Alpes, CEA, CNRS, Grenoble, France.

المصدر: Frontiers in immunology [Front Immunol] 2023 Apr 26; Vol. 14, pp. 1151731. Date of Electronic Publication: 2023 Apr 26 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Complement C1s* , HMGB1 Protein*, Humans ; Complement C4/metabolism ; Lipopolysaccharides ; Anti-Inflammatory Agents

المؤلفون: Amberger A; Institute of Human Genetics, Med. Univ. Innsbruck, Innsbruck, Austria., Pertoll J; Institute of Human Genetics, Med. Univ. Innsbruck, Innsbruck, Austria., Traunfellner P; Institute of Human Genetics, Med. Univ. Innsbruck, Innsbruck, Austria., Kapferer-Seebacher I; Department of Conservative Dentistry and Periodontology, Med. Univ. Innsbruck, Innsbruck, Austria., Stoiber H; Institute of Virology, Med. Univ. Innsbruck, Innsbruck, Austria., Klimaschewski L; Institute of Neuroanatomie, Med. Univ. Innsbruck., Innsbruck, Austria., Thielens N; Univ. Grenoble Alpes, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Centre National de la Recherche Scientifique (CNRS), Institut de Biologie Structurale (IBS), Grenoble, France., Gaboriaud C; Univ. Grenoble Alpes, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Centre National de la Recherche Scientifique (CNRS), Institut de Biologie Structurale (IBS), Grenoble, France., Zschocke J; Institute of Human Genetics, Med. Univ. Innsbruck, Innsbruck, Austria.

المصدر: Frontiers in immunology [Front Immunol] 2023 Mar 07; Vol. 14, pp. 1157421. Date of Electronic Publication: 2023 Mar 07 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Ehlers-Danlos Syndrome*/genetics , Ehlers-Danlos Syndrome*/pathology , Complement C1s*/genetics, Humans ; Collagen Type I/genetics ; Mutation, Missense

المؤلفون: Ye J; Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.; The Center for Translational Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China., Xu J; The Center for Translational Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China., Zhang C; The Center for Translational Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China., Zhu L; The Center for Translational Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China., Xia S; Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.

المصدر: Frontiers in immunology [Front Immunol] 2023 Jan 24; Vol. 14, pp. 1081793. Date of Electronic Publication: 2023 Jan 24 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Complement C1s* , Complement C1r*, Humans ; Fluorescence Resonance Energy Transfer ; Immunoassay ; Peptides ; Mannose-Binding Protein-Associated Serine Proteases

المؤلفون: Pitts JK; Department of Pharmacy, Licking Memorial Hospital, Newark, OH, USA., Burns DM; Department of Pharmacy, Licking Memorial Hospital, Newark, OH, USA., Patellos KR; Department of Pharmacy, Licking Memorial Hospital, Newark, OH, USA.

المصدر: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2024 Apr 19; Vol. 81 (9), pp. e220-e225.

نوع المنشور: Review; Case Reports; Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9503023 Publication Model: Print Cited Medium: Internet ISSN: 1535-2900 (Electronic) Linking ISSN: 10792082 NLM ISO Abbreviation: Am J Health Syst Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Complement C1 Inhibitor Protein*/therapeutic use , Angioedema*/chemically induced , Angioedema*/drug therapy, Humans ; Male ; Aged ; Tenecteplase/therapeutic use ; Complement C1s ; Fibrinolytic Agents/adverse effects ; Tissue Plasminogen Activator/adverse effects