نتائج البحث - "cAMP assays"

1

N6-[(Hetero)aryl/(cyclo)alkyl-carbamoyl-methoxy-phenyl]-(2-chloro)-5′-N-ethylcarboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A2B adenosine receptor

المؤلفون: Delia Preti, Francesca Fruttarolo, Allan R. Moorman, Pier Andrea Borea, Stefania Gessi, Pier Giovanni Baraldi, Mojgan Aghazadeh Tabrizi, Romeo Romagnoli, Stefania Baraldi, Katia Varani, Giulia Saponaro

المصدر: Bioorganic & Medicinal Chemistry. 15:2514-2527

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d2e5db5df34a5912a2893061478fe1
https://doi.org/10.1016/j.bmc.2007.01.055

View record from ScienceDirect

2

Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists

المؤلفون: Alessia Ligresti, Valentina Pedani, Francesca Guida, Katia Varani, Vincenzo Di Marzo, Nicolò Pesco, Federico Corelli, Simone Brogi, Claudia Mugnaini, Chiara Falciani, Serena Pasquini, Andrea Tafi, Pier Andrea Borea, Sabatino Maione, Livio Luongo

المساهمون: Pasquini, S, Mugnaini, C, Ligresti, A, Tafi, A, Brogi, S, Falciani, C, Pedani, V, Pesco, N, Guida, Francesca, Luongo, Livio, Varani, K, Borea, Pa, Maione, Sabatino, Di Marzo, V, Corelli, F.

المصدر: Journal of medicinal chemistry (Online) (2012).
info:cnr-pdr/source/autori:Pasquini S, Mugnaini C, Ligresti A, Tafi A, Brogi S, Falciani C, Pedani V, Pesco N, Guida F, Luongo L, Varani K, Borea PA, Maione S, Di Marzo V, Corelli F./titolo:Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists./doi:/rivista:Journal of medicinal chemistry (Online)/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume

مصطلحات موضوعية: Models, Molecular, Agonist, CB2 cannabinoid agonists, Indoles, Cannabinoid receptor, Drug Inverse Agonism, Cannabinoid Receptor Modulators, medicine.drug_class, Stereochemistry, medicine.medical_treatment, cAMP assays, Pain, Carboxamide, CHO Cells, Pharmacology, Receptor, Cannabinoid, CB2, Mice, Radioligand Assay, Structure-Activity Relationship, Cricetulus, cannabinoid receptors, Cricetinae, Drug Discovery, Cyclic AMP, medicine, Cannabinoid receptor type 2, Animals, Combinatorial Chemistry Techniques, Humans, Immunologic Factors, Inverse agonist, Receptor, Pain Measurement, Inflammation, binding experiments, Chemistry, Amides, HEK293 Cells, Drug Design, Molecular Medicine, lipids (amino acids, peptides, and proteins), Cannabinoid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9a30b43c97f7962456efaa6761e9a9
https://publications.cnr.it/doc/188575

3

4-amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as new potent and selective human A3 adenosine receptor antagonists. synthesis, pharmacological evaluation, and ligand-receptor modeling studies

المؤلفون: Stefano Moro, Flavia Varano, Ombretta Lenzi, Osele Ciampi, Vittoria Colotta, Katia Varani, Federico Marighetti, Erika Morizzo, Guido Filacchioni, Daniela Catarzi, Claudia Martini, Letizia Trincavelli

المصدر: Journal of medicinal chemistry. 49(13)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8b26bd3d6f3ee5b8f663e858b45f40
https://pubmed.ncbi.nlm.nih.gov/16789747

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4

BODIPY-conjugated neuropeptide Y ligands: new fluorescent tools to tag Y1, Y2, Y4 and Y5 receptor subtypes

المؤلفون: Dumont, Yvan, Gaudreau, Pierrette, Mazzuferi, Manuela, Langlois, Daniel, Chabot, Jean-Guy, Fournier, Alain, Simonato, Michele, Quirion, Rémi

المساهمون: Department of Psychiatry [Montréal], McGill University = Université McGill [Montréal, Canada], Laboratory of Neuroendocrinology of Aging, Notre-Dame Hospital and Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal (UdeM)-Université de Montréal (UdeM), Department of Clinical and Experimental Medicine (Section of Pharmacology) and Neuroscience Center, Università degli Studi di Ferrara (UniFE), Institut Armand Frappier (INRS-IAF), Réseau International des Instituts Pasteur (RIIP)-Institut National de la Recherche Scientifique [Québec] (INRS), This study was supported by grants from the Canadian Institutes of Health Research (CIHR)

المصدر: British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2005, 146 (8), pp.1069-81. ⟨10.1038/sj.bjp.0706425⟩

مصطلحات موضوعية: Boron Compounds, Male, MESH: Rats, receptor-binding assays, MESH: Boron Compounds, cAMP assays, MESH: Binding, Competitive, MESH: Rats, Sprague-Dawley, confocal microscopy, Ligands, Pancreatic Polypeptide, Transfection, Binding, Competitive, Cell Line, Rats, Sprague-Dawley, MESH: Brain, rat brain, cell imaging, MESH: Ligands, Cyclic AMP, Animals, Humans, MESH: Animals, Neuropeptide Y, Peptide YY, MESH: Neuropeptide Y, MESH: Peptide YY, MESH: Cyclic AMP, Fluorescent Dyes, MESH: Humans, MESH: Kinetics, MESH: Pancreatic Polypeptide, MESH: Transfection, Cell Membrane, Colforsin, Brain, MESH: Receptors, Neuropeptide Y, MESH: Fluorescent Dyes, MESH: Male, MESH: Cell Line, Rats, Receptors, Neuropeptide Y, Kinetics, NPY receptors, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Papers, BODIPY®NPY analogues, MESH: Forskolin, MESH: Cell Membrane