المؤلفون: Shin'ichi Takeda, Mutsuki Kuraoka, Yoshitsugu Aoki

المصدر: Experimental Animals

مصطلحات موضوعية: 0301 basic medicine, Duchenne muscular dystrophy, Male, Pathology, medicine.medical_specialty, osteopontin, Review, Muscle disorder, Motor Activity, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Dogs, Japan, Outcome Assessment, Health Care, medicine, accelerometry, X-linked muscular dystrophy, Animals, Humans, Osteopontin, Muscular dystrophy, General Veterinary, biology, outcome measure, business.industry, Muscle weakness, General Medicine, Young Investigator Award, medicine.disease, canine X-linked muscular dystrophy in Japan (CXMDJ), Gait, Muscular Dystrophy, Duchenne, Disease Models, Animal, 030104 developmental biology, biology.protein, Biomarker (medicine), Animal Science and Zoology, medicine.symptom, business, 030217 neurology & neurosurgery, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403a3075c7c2843f0178dbd0728fd88f
http://europepmc.org/articles/PMC8614006

المؤلفون: Yoshitsugu Aoki, A Arzumanov, Kamel Mamchaoui, Tone Yuichiro, Rika Maruyama, Graham McClorey, Shin'ichi Takeda, Toshifumi Yokota, Yasumasa Hashimoto, Maria K. Tsoumpra, Michihiro Imamura, Vincent Mouly, Michael J. Gait, Matthew J.A. Wood, Reiko Terada

المساهمون: Gestionnaire, HAL Sorbonne Université 5, Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Centre de recherche en Myologie – U974 SU-INSERM, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), University of Alberta, University of Oxford, UMRS974, Université Pierre et Marie Curie - Paris 6 (UPMC), University of Oxford [Oxford], Institut de Myologie, Centre National de la Recherche Scientifique (CNRS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Association française contre les myopathies (AFM-Téléthon)-Sorbonne Université (SU), Centre de Recherche en Myologie

المصدر: Nucleic Acid Therapeutics
Nucleic Acid Therapeutics, 2021, 31 (2), pp.172-181. ⟨10.1089/nat.2020.0907⟩
Nucleic Acid Therapeutics, Mary Ann Liebert, Inc. publishers, 2021, 31 (2), pp.172-181. ⟨10.1089/nat.2020.0907⟩

مصطلحات موضوعية: 0301 basic medicine, canine X-linked muscular dystrophy in Japan (CXMD J ), Duchenne muscular dystrophy, Biochemistry, Morpholinos, Dystrophin, Myoblasts, Mice, 0302 clinical medicine, Drug Discovery, Muscular dystrophy, Telomerase, ComputingMilieux_MISCELLANEOUS, biology, Chemistry, Myogenesis, phosphorodiamidate morpholino oligomer, Exons, Original Papers, 3. Good health, Cell biology, 030220 oncology & carcinogenesis, Molecular Medicine, [SDV.MHEP.AHA] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], splice-switching oligonucleotides, Nonsense mutation, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Cell Line, 03 medical and health sciences, Dogs, Genetics, medicine, [SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Animals, Humans, Telomerase reverse transcriptase, Molecular Biology, Cyclin-Dependent Kinase 4, Genetic Therapy, immortalized dystrophic canine myoblast, Oligonucleotides, Antisense, canine X-linked muscular dystrophy in Japan (CXMDJ), medicine.disease, Exon skipping, Muscular Dystrophy, Duchenne, 030104 developmental biology, biology.protein, Cell-penetrating peptide, RNA Splice Sites, Peptides, cell-penetrating peptide

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e6bb92dfaba5985c0590e408a2e368
https://hal.sorbonne-universite.fr/hal-03276095

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المؤلفون: Nakamura A; Third Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan. anakamu@shinshu-u.ac.jp.; Department of Neurology, Matsumoto Medical Center, National Hospital Organization, Matsumoto, Japan. anakamu@shinshu-u.ac.jp., Aoki Y; Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan., Tsoumpra M; Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan., Yokota T; Department of Medical Genetics, University of Alberta Faculty of Medicine and Dentistry, Edmonton, AB, Canada., Takeda S; Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1828, pp. 151-163.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Exons* , RNA Splicing*, Dystrophin/*genetics , Morpholinos/*genetics , Muscular Dystrophy, Duchenne/*genetics , Oligonucleotides, Antisense/*genetics, Animals ; Cells, Cultured ; Dogs ; Fibroblasts/metabolism ; Genetic Therapy ; Genetic Vectors/genetics ; Humans ; Morpholinos/administration & dosage ; Muscular Dystrophy, Duchenne/therapy ; MyoD Protein/genetics ; MyoD Protein/metabolism ; Myoblasts/metabolism ; Oligonucleotides, Antisense/administration & dosage ; Retroviridae/genetics ; Transduction, Genetic