المؤلفون: Li G; Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, School of Life Sciences, Hunan Normal University, Changsha, Hunan, China., Xiao K; Department of Neurosurgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China., Li Y; Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, School of Life Sciences, Hunan Normal University, Changsha, Hunan, China., Gao J; Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, School of Life Sciences, Hunan Normal University, Changsha, Hunan, China., He S; Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, School of Life Sciences, Hunan Normal University, Changsha, Hunan, China. hesp@hunnu.edu.cn., Li T; Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, School of Life Sciences, Hunan Normal University, Changsha, Hunan, China. tingtingli339@hunnu.edu.cn.

المصدر: Cellular oncology (Dordrecht, Netherlands) [Cell Oncol (Dordr)] 2024 Jun; Vol. 47 (3), pp. 851-865. Date of Electronic Publication: 2023 Nov 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 101552938 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3436 (Electronic) Linking ISSN: 22113428 NLM ISO Abbreviation: Cell Oncol (Dordr) Subsets: MEDLINE

مواضيع طبية MeSH: Ubiquitination* , Glioblastoma*/metabolism , Glioblastoma*/pathology , Glioblastoma*/genetics , Cell Proliferation* , Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , Brain Neoplasms*/metabolism , Brain Neoplasms*/pathology , Brain Neoplasms*/genetics, Humans ; Cell Line, Tumor ; Aspartate Carbamoyltransferase/metabolism ; Aspartate Carbamoyltransferase/genetics ; Proteolysis ; Apoptosis/genetics ; Dihydroorotase/metabolism ; Dihydroorotase/genetics ; Gene Expression Regulation, Neoplastic ; Tumor Stem Cell Assay ; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)

المؤلفون: Hu X; Department of Orthopedic Surgery, Hunan Provincial Children's Hospital, Changsha 410000, China., Yang F; Institute of Pharmacy and Pharmacology, Department of Pharmacy, Hunan Provincial People's Hospital, Changsha 410005, China., Mei H; Department of Orthopedic Surgery, Hunan Provincial Children's Hospital, Changsha 410000, China. Electronic address: haibomay1997@126.com.

المصدر: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association [J Orthop Sci] 2024 Jan; Vol. 29 (1), pp. 306-314. Date of Electronic Publication: 2022 Nov 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Japan NLM ID: 9604934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-2023 (Electronic) Linking ISSN: 09492658 NLM ISO Abbreviation: J Orthop Sci Subsets: MEDLINE

مواضيع طبية MeSH: Osteosarcoma*/metabolism , Signal Transduction* , Bone Neoplasms*/metabolism , Securin*/genetics, Humans ; Animals ; Mice ; Gene Knockdown Techniques ; Cell Movement ; Biomarkers, Tumor ; Prognosis ; Tumor Stem Cell Assay ; Neoplasm Invasiveness ; Cell Line, Tumor

المؤلفون: Fatehi-Agdam M; Students Research Committee, School of Medicine, Ardabil University of Medical Sciences, Ardabil.; Research Laboratory for Embryology and Stem Cells, Department of Anatomical Sciences, School of Medicine, Ardabil University of Medical Sciences, Ardabil., Vatankhah MA; Students Research Committee, School of Medicine, Ardabil University of Medical Sciences, Ardabil.; Research Laboratory for Embryology and Stem Cells, Department of Anatomical Sciences, School of Medicine, Ardabil University of Medical Sciences, Ardabil., Panahizadeh R; Students Research Committee, School of Medicine, Ardabil University of Medical Sciences, Ardabil.; Research Laboratory for Embryology and Stem Cells, Department of Anatomical Sciences, School of Medicine, Ardabil University of Medical Sciences, Ardabil., Jeddi F; Research Laboratory for Embryology and Stem Cells, Department of Anatomical Sciences, School of Medicine, Ardabil University of Medical Sciences, Ardabil., Najafzadeh N; Research Laboratory for Embryology and Stem Cells, Department of Anatomical Sciences, School of Medicine, Ardabil University of Medical Sciences, Ardabil.

المصدر: Drug research [Drug Res (Stuttg)] 2021 Jan; Vol. 71 (1), pp. 17-25. Date of Electronic Publication: 2020 Sep 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Thieme Country of Publication: Germany NLM ID: 101602406 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2194-9387 (Electronic) Linking ISSN: 21949379 NLM ISO Abbreviation: Drug Res (Stuttg) Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Stem Cell Assay*, Antineoplastic Combined Chemotherapy Protocols/*pharmacology , Metformin/*pharmacology , Stomach Neoplasms/*drug therapy, Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cell Line, Tumor ; Docetaxel/pharmacology ; Docetaxel/therapeutic use ; Drug Synergism ; Fluorouracil/pharmacology ; Fluorouracil/therapeutic use ; Gene Expression Regulation, Neoplastic/drug effects ; Hedgehog Proteins/metabolism ; Humans ; Metformin/therapeutic use ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Stomach Neoplasms/pathology ; Zinc Finger Protein GLI1/metabolism

المؤلفون: Mattei F; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy. fabrizio.mattei@iss.it., Andreone S; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy., Schiavoni G; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy. giovanna.schiavoni@iss.it.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2265, pp. 385-406.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Stem Cell Assay*, Lung Neoplasms/*metabolism , Melanoma, Experimental/*metabolism, Animals ; Cell Line, Tumor ; Lung Neoplasms/pathology ; Lung Neoplasms/secondary ; Melanoma, Experimental/pathology ; Mice ; Neoplasm Metastasis

المؤلفون: Khalili, Ehsan, Lakzaei, Mostafa, Aminian, Mahdi^{Aff1, IDs10529024034761_cor3}

المصدر: Biotechnology Letters. 46(3):385-398

المؤلفون: Matsui T; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan., Nuryadi E; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.; Department of Radiotherapy, Dr. Cipto Mangunkusumo National General Hospital - Faculty of Medicine Universitas Indonesia, Jakarta 10430, Indonesia., Komatsu S; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan., Hirota Y; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan., Shibata A; Gunma University Initiative for Advanced Research (GIAR), Gunma University, Maebashi 371-8511, Japan., Oike T; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan. oiketakahiro@gmail.com.; Gunma University Heavy Ion Medical Center, Maebashi 371-8511, Japan. oiketakahiro@gmail.com., Nakano T; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2019 Aug 25; Vol. 20 (17). Date of Electronic Publication: 2019 Aug 25.

نوع المنشور: Journal Article; Meta-Analysis

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers* , Radiation Tolerance* , Tumor Stem Cell Assay*, Cell Survival/*radiation effects, Cell Line, Tumor ; Humans ; Photons ; Radiotherapy ; Tumor Cells, Cultured

المؤلفون: Patra B; Institute of Biomedical Engineering, École Polytechnique de Montréal, Montréal, Qc, Canada.; Department of Engineering Physics, École Polytechnique de Montréal, Montréal, Qc, Canada.; Institut du Cancer de Montréal, Montréal, Qc, Canada., Lafontaine J; Institut du Cancer de Montréal, Montréal, Qc, Canada., Bavoux M; Institut du Cancer de Montréal, Montréal, Qc, Canada.; Department of Pharmacology and Physiology, Université de Montréal, Montréal, Qc, Canada.; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Qc, Canada., Zerouali K; Department of Radiation Oncology, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Qc, Canada., Glory A; Institut du Cancer de Montréal, Montréal, Qc, Canada.; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Qc, Canada., Ahanj M; Department of Radiation Oncology, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Qc, Canada., Carrier JF; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Qc, Canada.; Department of Radiation Oncology, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Qc, Canada., Gervais T; Institute of Biomedical Engineering, École Polytechnique de Montréal, Montréal, Qc, Canada.; Department of Engineering Physics, École Polytechnique de Montréal, Montréal, Qc, Canada.; Institut du Cancer de Montréal, Montréal, Qc, Canada.; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Qc, Canada., Wong P; Institut du Cancer de Montréal, Montréal, Qc, Canada. philip.wong.chum@ssss.gouv.qc.ca.; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Qc, Canada. philip.wong.chum@ssss.gouv.qc.ca.; Department of Radiation Oncology, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Qc, Canada. philip.wong.chum@ssss.gouv.qc.ca.

المصدر: Scientific reports [Sci Rep] 2019 Feb 18; Vol. 9 (1), pp. 2214. Date of Electronic Publication: 2019 Feb 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Flow Cytometry*/methods , Lab-On-A-Chip Devices* , Radiation, Ionizing* , Tumor Stem Cell Assay*, Antineoplastic Agents/*pharmacology , Cell Death/*drug effects , Cell Death/*radiation effects, Cell Line, Tumor ; Humans ; Radiation Dosage ; Sarcoma ; Soft Tissue Neoplasms ; Spheroids, Cellular ; Tumor Cells, Cultured

المؤلفون: Schubert, Steffen^{Aff1, IDs40629023002807_cor1}, Wolf, Carina, Schreiver, Ines, Siewert, Katherina, Karst, Uwe

المصدر: Allergo Journal International: Interdisciplinary Journal of Allergy, Clinical Immunology and Environmental Medicine. 33(2):60-66

المؤلفون: Bijian K; Segal Cancer Centre and Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Departments of Medicine and Oncology, McGill University, Montreal, Quebec H3A 0B8, Canada., Wernic D; Segal Cancer Centre and Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Departments of Medicine and Oncology, McGill University, Montreal, Quebec H3A 0B8, Canada., Nivedha AK; Department of Chemistry, McGill University, Montréal, Québec H3A 0B8, Canada.; Molecular Forecaster, 7171 rue Frederick Banting, Saint Laurent, Quebec H4S 1Z9, Canada., Su J; Segal Cancer Centre and Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Departments of Medicine and Oncology, McGill University, Montreal, Quebec H3A 0B8, Canada., Lim FPL; Department of Chemistry, McGill University, Montréal, Québec H3A 0B8, Canada., Miron CE; Department of Chemistry, McGill University, Montréal, Québec H3A 0B8, Canada., Amzil H; Segal Cancer Centre and Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Departments of Medicine and Oncology, McGill University, Montreal, Quebec H3A 0B8, Canada., Moitessier N; Department of Chemistry, McGill University, Montréal, Québec H3A 0B8, Canada., Alaoui-Jamali MA; Segal Cancer Centre and Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Departments of Medicine and Oncology, McGill University, Montreal, Quebec H3A 0B8, Canada.

المصدر: Journal of medicinal chemistry [J Med Chem] 2022 Feb 24; Vol. 65 (4), pp. 3134-3150. Date of Electronic Publication: 2022 Feb 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Aurora Kinase A/*antagonists & inhibitors , Protein Kinase C/*antagonists & inhibitors , Protein Kinase Inhibitors/*pharmacology , Selenium Compounds/*pharmacology, Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/drug therapy ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Female ; Humans ; Hydrogen Bonding ; Isoenzymes ; Molecular Docking Simulation ; Protein Kinase Inhibitors/chemistry ; Small Molecule Libraries ; Structure-Activity Relationship ; Substrate Specificity ; Tumor Stem Cell Assay

المؤلفون: Winter-Holt JJ, Bardelle C; BioPharmaceuticals R&D, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom., Chiarparin E, Dale IL, Davey PRJ, Davies NL, Denz C; Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Fillery SM, Guérot CM, Han F; Pharmaron Beijing Co. Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Hughes SJ, Kulkarni M; Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Liu Z; Pharmaron Beijing Co. Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Milbradt A, Moss TA, Niu H; Pharmaron Beijing Co. Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Patel J, Rabow AA, Schimpl M, Shi J; Pharmaron Beijing Co. Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Sun D; Pharmaron Beijing Co. Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Yang D; Pharmaron Beijing Co. Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Guichard S; Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2022 Feb 24; Vol. 65 (4), pp. 3306-3331. Date of Electronic Publication: 2022 Feb 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: ATPases Associated with Diverse Cellular Activities/*antagonists & inhibitors , Antineoplastic Agents/*chemical synthesis , Antineoplastic Agents/*pharmacology , Breast Neoplasms/*drug therapy , DNA-Binding Proteins/*antagonists & inhibitors, Cell Line, Tumor ; Crystallography, X-Ray ; Drug Discovery ; Drug Screening Assays, Antitumor ; Female ; Humans ; Models, Molecular ; Small Molecule Libraries ; Structure-Activity Relationship ; Substrate Specificity ; Tumor Stem Cell Assay