المؤلفون: Yang PS; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., He XY; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China.; School of Animal Science and Technology, Southwest University, Chongqing, P. R. China., Li SS; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Huang DQ; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Shen SY; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Liu XS; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Ma YY; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China.; Yunnan Key Laboratory of Tobacco Chemistry, China Tobacco Yunnan Industrial Co., Ltd, Kunming, P.R. China., Dong M; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Zhou M; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Yang FX; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China.; Yunnan Key Laboratory of Tobacco Chemistry, China Tobacco Yunnan Industrial Co., Ltd, Kunming, P.R. China., Li YK; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China.

المصدر: Natural product research [Nat Prod Res] 2024 Jul; Vol. 38 (14), pp. 2428-2435. Date of Electronic Publication: 2023 Feb 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE

مواضيع طبية MeSH: Chromones*/chemistry , Chromones*/pharmacology , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Antiviral Agents*/isolation & purification, Molecular Structure ; Magnetic Resonance Spectroscopy ; China ; Plant Extracts/chemistry ; Plant Extracts/pharmacology

المؤلفون: Yang YQ; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China., Liu YJ; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China., Qiao WX; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China., Jin W; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China., Zhu SW; Jiangsu Simcere Pharmaceutical Co., Ltd, Nanjing, 210042, China.; State Key Laboratory of Neurology and Oncology Drug Development, Nanjing, 210042, China., Yan YX; Jiangsu Simcere Pharmaceutical Co., Ltd, Nanjing, 210042, China.; State Key Laboratory of Neurology and Oncology Drug Development, Nanjing, 210042, China., Luo Q; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China. qiongluo@nju.edu.cn., Xu Q; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China. molpharm@163.com.; Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, 210023, China. molpharm@163.com.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2024 Sep; Vol. 45 (9), pp. 1926-1936. Date of Electronic Publication: 2024 May 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Sjogren's Syndrome*/drug therapy , Cell Differentiation*/drug effects , Protein-Tyrosine Kinases*/antagonists & inhibitors , Protein-Tyrosine Kinases*/metabolism , Plasma Cells*/drug effects , Chromones*/pharmacology , Chromones*/therapeutic use , Sulfonamides*/pharmacology , Sulfonamides*/therapeutic use, Animals ; Female ; Mice ; Benzofurans/pharmacology ; Benzofurans/therapeutic use ; Hydroxychloroquine/pharmacology ; Hydroxychloroquine/therapeutic use ; Disease Models, Animal ; Humans ; B-Lymphocytes/drug effects ; B-Lymphocytes/metabolism ; Antirheumatic Agents/pharmacology ; Antirheumatic Agents/therapeutic use

المؤلفون: Galla MS; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500037, India., Kale NB; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500037, India., Sharma A; Department of Biological Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500037, India., Hajare A; Department of Biological Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500037, India., Godugu C; Department of Biological Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500037, India., Shankaraiah N; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500037, India. Electronic address: shankar@niperhyd.ac.in.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Sep 01; Vol. 109, pp. 129853. Date of Electronic Publication: 2024 Jun 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*/drug effects , Chromones*/pharmacology , Chromones*/chemistry , Chromones*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Thiazolidinediones*/pharmacology , Thiazolidinediones*/chemistry , Thiazolidinediones*/chemical synthesis , Cell Proliferation*/drug effects , Drug Screening Assays, Antitumor*, Humans ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Molecular Docking Simulation ; HEK293 Cells ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Cell Line, Tumor

المؤلفون: Li X; Chemical Biology Research Center, School of Pharmaceutical Sciences, Chongqing University, 401331 Chongqing, China.; College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing 402160, China., An YN; College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing 402160, China., Fang BY; College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing 402160, China., Ju D; College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing 402160, China., Chen XY; College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing 402160, China., Chen XM; State Key Laboratory of Natural Medicines, Department of Pharmaceutical Engineering, China Pharmaceutical University, 211198 Nanjing, Jiangsu China., Xu ZG; College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing 402160, China.

المصدر: The Journal of organic chemistry [J Org Chem] 2024 Aug 16; Vol. 89 (16), pp. 11671-11681. Date of Electronic Publication: 2024 Aug 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Chromones*/chemistry , Chromones*/pharmacology , Chromones*/chemical synthesis , Lewis Acids*/chemistry, Humans ; Cell Line, Tumor ; Molecular Structure ; Drug Screening Assays, Antitumor ; Cell Proliferation/drug effects ; Catalysis ; Structure-Activity Relationship

المؤلفون: El-Gamil DS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt., Zaky MY; Zoology Department, Molecular Physiology Division, Faculty of Science, Beni-Suef University, Beni Suef, Egypt., Maximous PM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt., Sharaky M; Cancer Biology Department, Pharmacology Unit, National Cancer Institute (NCI), Cairo University, Cairo, Egypt.; Biochemistry Department, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt., El-Dessouki AM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt., Riad NM; Department of Chemistry, School of Life and Medical Sciences, New Administrative Capital, University of Hertfordshire hosted by Global Academic Foundation, Cairo, Egypt., Shaaban S; Department of Chemistry, College of Science, King Faisal University, Al-Ahsa, Saudi Arabia.; Organic Chemistry Division, Department of Chemistry, College of Science, Mansoura University, Mansoura, Egypt., Abdel-Halim M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt., Al-Karmalawy AA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, Egypt.

المصدر: Drug development research [Drug Dev Res] 2024 Aug; Vol. 85 (5), pp. e22228.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE

مواضيع طبية MeSH: ErbB Receptors*/antagonists & inhibitors , ErbB Receptors*/metabolism , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/metabolism , Triple Negative Breast Neoplasms*/pathology , Vascular Endothelial Growth Factor A*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Receptor, Fibroblast Growth Factor, Type 3*/antagonists & inhibitors , Receptor, Fibroblast Growth Factor, Type 3*/metabolism , Molecular Docking Simulation* , Chromones*/pharmacology , Chromones*/chemical synthesis , Chromones*/chemistry , Chromones*/therapeutic use, Humans ; Female ; Animals ; Cell Line, Tumor ; Mice ; Drug Design ; Apoptosis/drug effects ; Cell Proliferation/drug effects

المؤلفون: Chen KM; Department of Parasitology, Chung Shan Medical University, Taichung 402, Taiwan., Lai SC; Department of Parasitology, Chung Shan Medical University, Taichung 402, Taiwan; Clinical Laboratory, Chung Shan Medical University Hospital, Taichung 402, Taiwan. Electronic address: shih@csmu.edu.tw.

المصدر: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2024 Aug; Vol. 57 (4), pp. 647-659. Date of Electronic Publication: 2024 May 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: published by Elsevier for the Taiwan Society of Microbiology Country of Publication: England NLM ID: 100956211 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1995-9133 (Electronic) Linking ISSN: 16841182 NLM ISO Abbreviation: J Microbiol Immunol Infect Subsets: MEDLINE

مواضيع طبية MeSH: Angiostrongylus cantonensis*/drug effects , Meningoencephalitis*/drug therapy , Meningoencephalitis*/parasitology , Strongylida Infections*/drug therapy , Chromones*/pharmacology , Chromones*/therapeutic use , Morpholines*/pharmacology , Morpholines*/therapeutic use, Animals ; Mice ; Signal Transduction/drug effects ; Male ; Receptor, Platelet-Derived Growth Factor beta/metabolism ; Blood-Brain Barrier/drug effects ; Disease Models, Animal ; Phosphatidylinositol 3-Kinases/metabolism ; Anthelmintics/therapeutic use ; Anthelmintics/pharmacology ; Matrix Metalloproteinase 9/metabolism ; Eosinophilia/drug therapy ; Drug Therapy, Combination ; Sulfonamides

SCR Disease Name: Angiostrongyliasis

المؤلفون: Alharthy RD; Department of Chemistry, Science & Arts College, Rabigh Branch, King Abdulaziz University, Rabigh, Saudi Arabia., Khalid S; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan., Fatima S; Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan., Ullah S; Natural and Medical Sciences Research Centre, University of Nizwa, Nizwa, Sultanate of Oman., Khan A; Natural and Medical Sciences Research Centre, University of Nizwa, Nizwa, Sultanate of Oman., Mali SN; Department of Pharmaceutical Science and Technology, Birla Institute of Technology, Mesra, India., Jawarkar RD; Department of Medicinal Chemistry and Drug Discovery, Dr. Rajendra Gode Institute of Pharmacy, Amravati, India., Dhabarde SS; Department of Chemistry, K. V. Pendharkar College, Thane, India., Kashtoh H; Department of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, Republic of Korea., Taslimi P; Department of Biotechnology, Faculty of Science, Bartin University, Bartin, Turkey., Al-Harrasi A; Natural and Medical Sciences Research Centre, University of Nizwa, Nizwa, Sultanate of Oman., Shafiq Z; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan., Boshta NM; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt.

المصدر: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Aug; Vol. 357 (8), pp. e2400140. Date of Electronic Publication: 2024 Apr 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

مواضيع طبية MeSH: Glycoside Hydrolase Inhibitors*/pharmacology , Glycoside Hydrolase Inhibitors*/chemical synthesis , Glycoside Hydrolase Inhibitors*/chemistry , Hypoglycemic Agents*/pharmacology , Hypoglycemic Agents*/chemical synthesis , Hypoglycemic Agents*/chemistry , Drug Design* , Molecular Docking Simulation* , Chromones*/pharmacology , Chromones*/chemical synthesis , Chromones*/chemistry , alpha-Glucosidases*/metabolism , Thiosemicarbazones*/pharmacology , Thiosemicarbazones*/chemistry , Thiosemicarbazones*/chemical synthesis , Diabetes Mellitus, Type 2*/drug therapy, Structure-Activity Relationship ; Molecular Structure ; Humans ; Molecular Dynamics Simulation ; Computer Simulation ; Dose-Response Relationship, Drug

المؤلفون: Fan X; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, and School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, 110016, PR China., Guo J; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, and School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, 110016, PR China., Feng D; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, and School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, 110016, PR China., Li D; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, and School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, 110016, PR China. Electronic address: lidahong0203@163.com., Hua H; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, and School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, 110016, PR China. Electronic address: huimhua@163.com.

المصدر: Phytochemistry [Phytochemistry] 2024 Aug; Vol. 224, pp. 114166. Date of Electronic Publication: 2024 May 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Garcinia*/chemistry , Biflavonoids*/chemistry , Biflavonoids*/pharmacology , Biflavonoids*/isolation & purification , Chromones*/chemistry , Chromones*/pharmacology , Chromones*/isolation & purification , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/chemistry , Anti-Inflammatory Agents*/isolation & purification, Mice ; Animals ; RAW 264.7 Cells ; Structure-Activity Relationship ; Molecular Structure ; Lipopolysaccharides/pharmacology ; Lipopolysaccharides/antagonists & inhibitors ; Nitric Oxide/antagonists & inhibitors ; Nitric Oxide/biosynthesis ; Dose-Response Relationship, Drug

المؤلفون: Kanzouai Y; Engineering Laboratory of Organometallic and Molecular Materials and Environment, Department of Chemistry, Faculty of Sciences Dhar El Mahraz, University of Sidi Mohamed Ben Abdellah, Fez, Morocco., Laghmari M; Laboratory of Natural Resources and Environment, Department of Biology Polydisciplinary Faculty of Taza, Sidi Mohamed Ben Abdellah University, Taza, Morocco., Yamari I; Laboratory of Analytical and Molecular Chemistry, Department of Chemistry, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Casablanca, Morocco., Bouzammit R; Engineering Laboratory of Organometallic and Molecular Materials and Environment, Department of Chemistry, Faculty of Sciences Dhar El Mahraz, University of Sidi Mohamed Ben Abdellah, Fez, Morocco., Bahsis L; Laboratoire de Chimie Analytique et Moléculaire, LCAM, Département de Chimie, Faculté Polydisciplinaire de Safi, Université Cadi Ayyad, Safi, Morocco., Benali T; Laboratory of Natural Resources and Environment, Department of Biology Polydisciplinary Faculty of Taza, Sidi Mohamed Ben Abdellah University, Taza, Morocco.; Environment and Health Team, Polydisciplinary Faculty of Safi, Department of Biology, Cadi Ayyad University, Safi, Morocco., Chtita S; Laboratory of Analytical and Molecular Chemistry, Department of Chemistry, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Casablanca, Morocco., Bakhouch M; Bioorganic Chemistry Team, Department of Chemistry, Faculty of Sciences, University Chouaïb Doukkali, El Jadida, Morocco., Akhazzane M; Cité de l'innovation, Université Sidi Mohamed Ben Abdellah, Fez, Morocco., El Kouali M; Laboratory of Analytical and Molecular Chemistry, Department of Chemistry, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Casablanca, Morocco., Hammani K; Laboratory of Natural Resources and Environment, Department of Biology Polydisciplinary Faculty of Taza, Sidi Mohamed Ben Abdellah University, Taza, Morocco., Al Houari G; Engineering Laboratory of Organometallic and Molecular Materials and Environment, Department of Chemistry, Faculty of Sciences Dhar El Mahraz, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Aug; Vol. 42 (12), pp. 6410-6424. Date of Electronic Publication: 2023 Oct 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Docking Simulation* , Molecular Dynamics Simulation* , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemical synthesis , Isoxazoles*/chemistry , Chromones*/chemistry , Chromones*/chemical synthesis, Catalytic Domain ; Staphylococcus aureus/drug effects ; Microbial Sensitivity Tests ; Molecular Conformation ; Molecular Structure ; Structure-Activity Relationship

المؤلفون: Zou DJ; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China. zhangchangjun@zjut.edu.cn.; School of Ethnic-Minority Medicine, Guizhou Minzu University, Guiyang 50025, China., Liu RZ; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China. zhangchangjun@zjut.edu.cn., Lv YJ; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China. zhangchangjun@zjut.edu.cn., Guo JN; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China. zhangchangjun@zjut.edu.cn., Fan ML; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China. zhangchangjun@zjut.edu.cn., Zhang CJ; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China. zhangchangjun@zjut.edu.cn., Xie YY; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China. zhangchangjun@zjut.edu.cn.; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceutical, Zhejiang University of Technology, Hangzhou, China.; Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of Education, Key Laboratory of Pharmaceutical Engineering of Zhejiang Province, Hangzhou, 310014, China. xyycz@zjut.edu.cn.

المصدر: Organic & biomolecular chemistry [Org Biomol Chem] 2024 Jul 31; Vol. 22 (30), pp. 6189-6197. Date of Electronic Publication: 2024 Jul 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Monoamine Oxidase Inhibitors*/pharmacology , Monoamine Oxidase Inhibitors*/chemistry , Monoamine Oxidase Inhibitors*/chemical synthesis , Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism , Iron Chelating Agents*/pharmacology , Iron Chelating Agents*/chemistry , Iron Chelating Agents*/chemical synthesis , Deferiprone*/pharmacology , Deferiprone*/chemistry , Monoamine Oxidase*/metabolism , Chromones*/chemistry , Chromones*/pharmacology , Chromones*/chemical synthesis, Humans ; Structure-Activity Relationship ; Animals ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Antioxidants/chemical synthesis ; Ferroptosis/drug effects ; Molecular Structure ; Molecular Docking Simulation ; Blood-Brain Barrier/metabolism ; Blood-Brain Barrier/drug effects ; Dose-Response Relationship, Drug