المؤلفون: Cheng X; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA., Baki VB; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA., Moran M; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA., Liu B; Department of Nutrition and Health Sciences, University of Nebraska - Lincoln, 230 Filley Hall, Lincoln, NE 68583-0922, USA., Yu J; Department of Nutrition and Health Sciences, University of Nebraska - Lincoln, 230 Filley Hall, Lincoln, NE 68583-0922, USA., Zhao M; Nebraska Center for Virology, School of Biological Sciences, University of Nebraska - Lincoln, Lincoln, NE, USA., Li Q; Nebraska Center for Virology, School of Biological Sciences, University of Nebraska - Lincoln, Lincoln, NE, USA., Riethoven JJ; Nebraska Center for Biotechnology, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA; Nebraska Center for Integrated Biomolecular Communication (NCIBC), University of Nebraska - Lincoln, Lincoln, NE 68588, USA., Gurumurth CB; Mouse Genome Engineering Core Facility, University of Nebraska Medical Center, Omaha, USA., Harris EN; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA; Nebraska Center for Integrated Biomolecular Communication (NCIBC), University of Nebraska - Lincoln, Lincoln, NE 68588, USA; Nebraska Center for the Prevention of Obesity Diseases through Dietary Molecules, University of Nebraska - Lincoln, USA., Sun X; Department of Biochemistry, University of Nebraska - Lincoln, Beadle Center, 1901 Vine St, Lincoln, NE 68588, USA; Nebraska Center for Integrated Biomolecular Communication (NCIBC), University of Nebraska - Lincoln, Lincoln, NE 68588, USA; Nebraska Center for the Prevention of Obesity Diseases through Dietary Molecules, University of Nebraska - Lincoln, USA. Electronic address: xsun17@unl.edu.

المصدر: Molecular metabolism [Mol Metab] 2024 Aug; Vol. 86, pp. 101977. Date of Electronic Publication: 2024 Jun 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Constitutive Androstane Receptor* , Fatty Liver*/metabolism , Fatty Liver*/genetics , Liver*/metabolism , Mice, Knockout*, Animals ; Male ; Mice ; Diet, High-Fat/adverse effects ; Mice, Inbred C57BL ; Non-alcoholic Fatty Liver Disease/metabolism ; Non-alcoholic Fatty Liver Disease/genetics ; RNA-Binding Proteins/metabolism ; RNA-Binding Proteins/genetics ; Signal Transduction ; Stress, Physiological

المؤلفون: Sonkar R; Department of Biology and Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA., Ma H; Department of Biology and Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA., Waxman DJ; Department of Biology and Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2024 Aug 01; Vol. 200 (2), pp. 324-345.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Constitutive Androstane Receptor* , Receptors, Cytoplasmic and Nuclear*/genetics , Receptors, Cytoplasmic and Nuclear*/metabolism , Disease Progression* , Pyridines*/toxicity , Pyridines*/pharmacology , Fatty Liver*/chemically induced , Fatty Liver*/pathology , Fatty Liver*/genetics , Fatty Liver*/metabolism, Animals ; Male ; Female ; Mice ; Liver/drug effects ; Liver/pathology ; Liver/metabolism

المؤلفون: Kotulkar M; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, United States., Paine-Cabrera D; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, United States., Robarts DR; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, United States., Apte U; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, United States.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2024 Aug 01; Vol. 200 (2), pp. 346-356.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Hepatocyte Nuclear Factor 4*/metabolism , Hepatocyte Nuclear Factor 4*/genetics , Liver*/metabolism , Liver*/drug effects , PPAR alpha*/agonists , PPAR alpha*/metabolism , PPAR alpha*/genetics , Mice, Knockout* , Constitutive Androstane Receptor* , Pregnane X Receptor*/genetics , Pregnane X Receptor*/metabolism , Receptors, Cytoplasmic and Nuclear*/genetics , Receptors, Cytoplasmic and Nuclear*/agonists , Receptors, Cytoplasmic and Nuclear*/metabolism, Animals ; Mice ; Receptors, Steroid/genetics ; Receptors, Steroid/metabolism ; Receptors, Steroid/agonists ; Receptors, Aryl Hydrocarbon/agonists ; Receptors, Aryl Hydrocarbon/genetics ; Receptors, Aryl Hydrocarbon/metabolism ; Mice, Inbred C57BL ; Male ; Pyrimidines/pharmacology ; Polychlorinated Dibenzodioxins/toxicity ; Pyridines/pharmacology

المؤلفون: Goettel M; BASF SE, Global Toxicology Agricultural Solutions, Speyerer Strasse 2, Limburgerhof 67117, Germany. Electronic address: manuela.goettel@basf.com., Werner C; BASF SE, Global Toxicology Agricultural Solutions, Speyerer Strasse 2, Limburgerhof 67117, Germany., Honarvar N; BASF SE, Experimental Toxicology and Ecology, Carl-Bosch-Strasse 38, Ludwigshafen am Rhein 67056, Germany., Gröters S; BASF SE, Experimental Toxicology and Ecology, Carl-Bosch-Strasse 38, Ludwigshafen am Rhein 67056, Germany., Fegert I; BASF SE, Global Toxicology Agricultural Solutions, Speyerer Strasse 2, Limburgerhof 67117, Germany., Haines C; Concept Life Sciences Ltd., 2, James Lindsay Place, Dundee Technopole, Dundee DD1 5JJ, United Kingdom., Chatham LR; Concept Life Sciences Ltd., 2, James Lindsay Place, Dundee Technopole, Dundee DD1 5JJ, United Kingdom., Vardy A; Concept Life Sciences Ltd., 2, James Lindsay Place, Dundee Technopole, Dundee DD1 5JJ, United Kingdom., Lake BG; School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK.

المصدر: Toxicology [Toxicology] 2024 Jun; Vol. 505, pp. 153828. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185 (Electronic) Linking ISSN: 0300483X NLM ISO Abbreviation: Toxicology Subsets: MEDLINE

مواضيع طبية MeSH: Rats, Wistar* , Fungicides, Industrial*/toxicity , Receptors, Cytoplasmic and Nuclear*/metabolism , Receptors, Cytoplasmic and Nuclear*/genetics , Constitutive Androstane Receptor* , Hepatocytes*/drug effects , Hepatocytes*/metabolism , Hepatocytes*/pathology, Animals ; Male ; Female ; Rats ; Humans ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Dose-Response Relationship, Drug ; Organ Size/drug effects ; Liver Neoplasms, Experimental/chemically induced ; Liver Neoplasms, Experimental/pathology ; Liver Neoplasms, Experimental/metabolism ; DNA Replication/drug effects ; Cytochrome P-450 Enzyme System/metabolism ; Cytochrome P-450 Enzyme System/genetics ; Microsomes, Liver/drug effects ; Microsomes, Liver/metabolism ; Liver Neoplasms/chemically induced ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology

المؤلفون: Zhao P; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (P.Z., S.F., H.B.); Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (P.Z., S.F., Y.Z., M.H., Y.G., H.B.); and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, 518055, China (H.B.)., Fan S; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (P.Z., S.F., H.B.); Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (P.Z., S.F., Y.Z., M.H., Y.G., H.B.); and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, 518055, China (H.B.)., Zhou Y; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (P.Z., S.F., H.B.); Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (P.Z., S.F., Y.Z., M.H., Y.G., H.B.); and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, 518055, China (H.B.)., Huang M; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (P.Z., S.F., H.B.); Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (P.Z., S.F., Y.Z., M.H., Y.G., H.B.); and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, 518055, China (H.B.)., Gao Y; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (P.Z., S.F., H.B.); Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (P.Z., S.F., Y.Z., M.H., Y.G., H.B.); and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, 518055, China (H.B.) bihchang@smu.edu.cn gaoy46@mail2.sysu.edu.cn., Bi H; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (P.Z., S.F., H.B.); Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (P.Z., S.F., Y.Z., M.H., Y.G., H.B.); and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, 518055, China (H.B.) bihchang@smu.edu.cn gaoy46@mail2.sysu.edu.cn.

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2024 Jun 21; Vol. 390 (1), pp. 88-98. Date of Electronic Publication: 2024 Jun 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Constitutive Androstane Receptor* , PPAR alpha*/metabolism, Humans ; Receptors, Cytoplasmic and Nuclear/metabolism ; Animals ; Osmotic Pressure ; Phase Separation

المؤلفون: Liu J; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Malekoltojari A; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Asokakumar A; Department of Molecular and Integrative Physiology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA., Chow V; Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada., Li L; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn Street, Baltimore, MD, 21201, USA., Li H; Department of Molecular Pharmacology; Department of Genetics; Department of Medicine; Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Grimaldi M; Institut de Recherche en Cancérologie de Montpellier (IRCM), Université Montpellier, Institut régional du Cancer de Montpellier (ICM), Montpellier, Inserm, U1194, France., Dang N; Department of Molecular and Integrative Physiology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA., Campbell J; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Barrett H; Department of Chemistry, University of Toronto, Toronto, ON, M5S 3H6, Canada., Sun J; Department of Chemistry, University of Toronto, Toronto, ON, M5S 3H6, Canada.; School of the Environment, University of Toronto, Toronto, ON, M5S 3H6, Canada., Navarre W; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Wilson D; Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada., Wang H; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn Street, Baltimore, MD, 21201, USA., Mani S; Department of Molecular Pharmacology; Department of Genetics; Department of Medicine; Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Balaguer P; Institut de Recherche en Cancérologie de Montpellier (IRCM), Université Montpellier, Institut régional du Cancer de Montpellier (ICM), Montpellier, Inserm, U1194, France., Anakk S; Department of Molecular and Integrative Physiology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA., Peng H; Department of Chemistry, University of Toronto, Toronto, ON, M5S 3H6, Canada. hui.peng@utoronto.ca.; School of the Environment, University of Toronto, Toronto, ON, M5S 3H6, Canada. hui.peng@utoronto.ca., Krause HM; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada. h.krause@utoronto.ca.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. h.krause@utoronto.ca.

المصدر: Nature communications [Nat Commun] 2024 Mar 22; Vol. 15 (1), pp. 2563. Date of Electronic Publication: 2024 Mar 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Constitutive Androstane Receptor* , Microbiota*, Mice ; Animals ; Humans ; Receptors, Cytoplasmic and Nuclear/metabolism ; Hepatocytes/metabolism ; Ligands

المؤلفون: Shizu R; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan., Makida N; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan., Sobe K; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan., Ishimura M; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan., Takeshita A; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan., Hosaka T; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan., Kanno Y; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan., Sasaki T; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan., Yoshinari K; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, Japan.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2024 Feb 28; Vol. 198 (1), pp. 101-112.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Constitutive Androstane Receptor* , Rodentia*, Animals ; Humans ; Mice ; Cell Proliferation ; Hepatocytes/metabolism ; Liver/metabolism ; Species Specificity

المؤلفون: Sekiguchi M; Department of Food Science, Faculty of Bioresources and Environmental Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan., Fujinami Y; Department of Food Science, Faculty of Bioresources and Environmental Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan., Takado K; Department of Food Science, Faculty of Bioresources and Environmental Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan., Kimoto Y; Department of Food Science, Faculty of Bioresources and Environmental Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan., Higashimura Y; Department of Food Science, Faculty of Bioresources and Environmental Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.

المصدر: Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2023 Oct 25; Vol. 87 (11), pp. 1310-1315.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9205717 Publication Model: Print Cited Medium: Internet ISSN: 1347-6947 (Electronic) Linking ISSN: 09168451 NLM ISO Abbreviation: Biosci Biotechnol Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Constitutive Androstane Receptor* , Diterpenes*/pharmacology, Humans ; Receptors, Cytoplasmic and Nuclear

المؤلفون: Brožová ZR; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Dušek J; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic; Department of Physiology, Faculty of Medicine in Hradec Králové, Charles University, Šimkova 870, 500 03, Hradec Králové, Czech Republic., Palša N; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Maixnerová J; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Kamaraj R; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Smutná L; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Matouš P; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Braeuning A; Department of Food Safety, German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany., Pávek P; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Kuneš J; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Gathergood N; School of Chemistry, University of Lincoln, Joseph Banks Laboratories, Green Lane, Lincoln, Lincolnshire, LN6 7DL, United Kingdom., Špulák M; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic., Pour M; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic. Electronic address: pour@faf.cuni.cz., Carazo A; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic. Electronic address: carazofa@faf.cuni.cz.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2023 Nov 05; Vol. 259, pp. 115631. Date of Electronic Publication: 2023 Jul 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Constitutive Androstane Receptor* , Receptors, Steroid*/agonists , Receptors, Steroid*/metabolism, Humans ; Receptors, Cytoplasmic and Nuclear ; Ligands ; Quinazolines/pharmacology ; Thiones

المؤلفون: Mazin ME; Novosibirsk State University, Novosibirsk, 630090, Russia.; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia., Perevalova AM; Novosibirsk State University, Novosibirsk, 630090, Russia., Yarushkin AA; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia., Pustylnyak YA; Novosibirsk State University, Novosibirsk, 630090, Russia., Rogachev AD; Novosibirsk State University, Novosibirsk, 630090, Russia., Prokopyeva EA; Novosibirsk State University, Novosibirsk, 630090, Russia.; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia., Gulyaeva LF; Novosibirsk State University, Novosibirsk, 630090, Russia.; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia., Pustylnyak VO; Novosibirsk State University, Novosibirsk, 630090, Russia. pustylnyak@post.nsu.ru.; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia.

المصدر: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2023 Aug; Vol. 88 (8), pp. 1061-1069.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MAIK Nauka/Interperiodica Country of Publication: United States NLM ID: 0376536 Publication Model: Print Cited Medium: Internet ISSN: 1608-3040 (Electronic) Linking ISSN: 00062979 NLM ISO Abbreviation: Biochemistry (Mosc) Subsets: MEDLINE

مواضيع طبية MeSH: Constitutive Androstane Receptor*/agonists , Receptors, Cytoplasmic and Nuclear*/metabolism, Animals ; Male ; Mice ; Cell Proliferation ; Hepatocytes/metabolism ; Hyperplasia/metabolism ; Hyperplasia/pathology ; Liver/metabolism ; Mice, Inbred C57BL