المؤلفون: Jerry L; Clinical Pharmacology, Pfizer Inc., New York, New York, USA., Swan L; Clinical Pharmacology, Neurocrine Biosciences, San Diego, California, USA., Dana N; Clinical Pharmacology, Pfizer Inc., New York, New York, USA., Balis FM; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Greengard E; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA., Huiping X; Clinical Pharmacology, Pfizer Inc., New York, New York, USA.

المصدر: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Sep; Vol. 71 (9), pp. e31139. Date of Electronic Publication: 2024 Jun 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Crizotinib*/therapeutic use , Crizotinib*/pharmacokinetics , Anaplastic Lymphoma Kinase*/antagonists & inhibitors , Anaplastic Lymphoma Kinase*/genetics , Protein Kinase Inhibitors*/therapeutic use , Protein Kinase Inhibitors*/pharmacokinetics , Protein Kinase Inhibitors*/adverse effects, Humans ; Child ; Female ; Male ; Adolescent ; Child, Preschool ; Neoplasms/drug therapy ; Neoplasms/pathology ; Lymphoma, Large-Cell, Anaplastic/drug therapy ; Lymphoma, Large-Cell, Anaplastic/pathology ; Young Adult ; Infant

المؤلفون: Wang H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, PR China., Chen H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, PR China., Cui X; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, PR China., Zhang Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, PR China., Zhou J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China., Chen X; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, PR China; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, PR China. Electronic address: xychen@simm.ac.cn.

المصدر: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2024 Aug 15; Vol. 246, pp. 116199. Date of Electronic Publication: 2024 May 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

مواضيع طبية MeSH: Tandem Mass Spectrometry*/methods , Crizotinib*/blood , Crizotinib*/pharmacokinetics , Rats, Sprague-Dawley*, Animals ; Rats ; Male ; Chromatography, Liquid/methods ; Protein Kinase Inhibitors/pharmacokinetics ; Protein Kinase Inhibitors/blood ; Reproducibility of Results ; Hydrolysis ; Pyridines/blood ; Pyridines/pharmacokinetics ; Pyrazoles/blood ; Pyrazoles/pharmacokinetics ; Liquid Chromatography-Mass Spectrometry

المؤلفون: Li Z; Department of Respiratory Diseases, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Ma X; Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Laboratory of Advanced Theranostic Materials and Technology, Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China; Zhejiang International Cooperation Base of Biomedical Materials Technology and Application Zhejiang Engineering Research Center for Biomedical Materials, Ningbo Cixi Institute of Biomedical Engineering, Ningbo 315300, China. Electronic address: maxh@nimte.ac.cn., Yang Y; Department of Respiratory Diseases, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China., Wang Y; Cixi Biomedical Research Institute, Wenzhou Medical University, Zhejiang 315300, China., Zhu W; Cixi Biomedical Research Institute, Wenzhou Medical University, Zhejiang 315300, China., Deng X; Cixi Biomedical Research Institute, Wenzhou Medical University, Zhejiang 315300, China., Chen T; Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Laboratory of Advanced Theranostic Materials and Technology, Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China; Zhejiang International Cooperation Base of Biomedical Materials Technology and Application Zhejiang Engineering Research Center for Biomedical Materials, Ningbo Cixi Institute of Biomedical Engineering, Ningbo 315300, China., Gao C; Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Laboratory of Advanced Theranostic Materials and Technology, Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China; Zhejiang International Cooperation Base of Biomedical Materials Technology and Application Zhejiang Engineering Research Center for Biomedical Materials, Ningbo Cixi Institute of Biomedical Engineering, Ningbo 315300, China., Zhang Y; The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China., Yang W; Department of Respiratory Diseases, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Xing H; Department of Respiratory Diseases, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Ye X; Department of Respiratory Diseases, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China. Electronic address: xiaoqunye@ndefy.ntesmail.com., Wu A; Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Laboratory of Advanced Theranostic Materials and Technology, Chinese Academy of Sciences (CAS) Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China; Zhejiang International Cooperation Base of Biomedical Materials Technology and Application Zhejiang Engineering Research Center for Biomedical Materials, Ningbo Cixi Institute of Biomedical Engineering, Ningbo 315300, China; Cixi Biomedical Research Institute, Wenzhou Medical University, Zhejiang 315300, China. Electronic address: aiguo@nimte.ac.cn., Zhang X; Department of Respiratory Diseases, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China. Electronic address: zhangxinyi@jxndefy.cn.

المصدر: Acta biomaterialia [Acta Biomater] 2024 Sep 01; Vol. 185, pp. 381-395. Date of Electronic Publication: 2024 Jul 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE

مواضيع طبية MeSH: Mitochondria*/metabolism , Mitochondria*/drug effects , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Lung Neoplasms*/metabolism , Drug Resistance, Neoplasm*/drug effects , Crizotinib*/pharmacology , Anaplastic Lymphoma Kinase*/metabolism , Zeolites*/chemistry , Zeolites*/pharmacology , Imidazoles*/pharmacology , Imidazoles*/chemistry, Humans ; Animals ; Cell Line, Tumor ; Metal-Organic Frameworks/chemistry ; Metal-Organic Frameworks/pharmacology ; Mice ; Mice, Nude ; Photochemotherapy

المؤلفون: Guo L; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Ma J; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Xiao M; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Liu J; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Hu Z; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Xia S; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Li N; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China., Yang Y; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China.; Department of Pharmacy, Wuzhou Gongren Hospital, Wuzhou, China., Gong H; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Xi Y; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Fu R; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China., Jiang P; Department of Pharmacy, Jining No 1 People's Hospital, Jining Medical University, Jining, China., Xia C; Chia Tai Tianqing Pharmaceutical Group Co. Ltd, Lianyungang, Jiangsu, China., Lauschke VM; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China.; Institute of Clinical Pharmacy, Central South University, Changsha, China.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China.; Department of Physiology and Pharmacology, Section of Pharmacogenetics, Karolinska Institutet, SE-171 77, Stockholm, Sweden., Yan M; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China. yanmiao@csu.edu.cn.; Institute of Clinical Pharmacy, Central South University, Changsha, China. yanmiao@csu.edu.cn.; International Research Center for Precision Medicine, Transformative Technology and Software Services, Hunan, China. yanmiao@csu.edu.cn.

المصدر: Cell death & disease [Cell Death Dis] 2024 Aug 19; Vol. 15 (8), pp. 600. Date of Electronic Publication: 2024 Aug 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis*/drug effects , NF-E2-Related Factor 2*/metabolism , Crizotinib*/pharmacology , Crizotinib*/adverse effects , Chemical and Drug Induced Liver Injury*/metabolism , Chemical and Drug Induced Liver Injury*/pathology , Chemical and Drug Induced Liver Injury*/genetics , STAT1 Transcription Factor*/metabolism , STAT1 Transcription Factor*/genetics, Humans ; Animals ; Mice ; Signal Transduction/drug effects ; Male ; Phenylenediamines/pharmacology ; Mice, Inbred C57BL ; Hepatocytes/metabolism ; Hepatocytes/drug effects ; Phosphorylation/drug effects

المؤلفون: Xu Y; Department of Respiratory and Critical Care Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhang Y; Department of Respiratory and Critical Care Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Qiang H; Department of Respiratory and Critical Care Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhong H; Department of Respiratory and Critical Care Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Xu J; Department of Respiratory and Critical Care Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhong R; Department of Respiratory and Critical Care Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: tonic_chung@139.com.

المصدر: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2024 Aug; Vol. 194, pp. 107892. Date of Electronic Publication: 2024 Jul 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8800805 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8332 (Electronic) Linking ISSN: 01695002 NLM ISO Abbreviation: Lung Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Crizotinib*/therapeutic use , Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/mortality , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/mortality , Proto-Oncogene Proteins*/genetics , B7-H1 Antigen*/genetics , B7-H1 Antigen*/metabolism , Protein-Tyrosine Kinases*/genetics , Gene Rearrangement* , Protein Kinase Inhibitors*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Aged ; Adult ; Retrospective Studies ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Prognosis

المؤلفون: Wang B; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China., Lao HY; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China., Yuan J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China.

المصدر: Ophthalmology [Ophthalmology] 2024 Aug; Vol. 131 (8), pp. 966. Date of Electronic Publication: 2023 Oct 20.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE

مواضيع طبية MeSH: Scleritis*/drug therapy , Scleritis*/chemically induced , Scleritis*/diagnosis , Crizotinib*/adverse effects , Crizotinib*/therapeutic use, Humans ; Lung Neoplasms/drug therapy ; Protein Kinase Inhibitors/adverse effects ; Protein Kinase Inhibitors/therapeutic use ; Male ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Necrosis/chemically induced ; Female ; Middle Aged

المؤلفون: Nosaki K; Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan., Yoh K; Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan. kyoh@east.ncc.go.jp., Toyozawa R; Department of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan., Horinouchi H; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Morise M; Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan., Ohashi K; Department of Respiratory Medicine, Okayama University Hospital, Okayama, Japan., Murakami H; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Satouchi M; Department of Thoracic Oncology, Hyogo Cancer Center, Akashi, Japan., Sakakibara-Konishi J; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, Sapporo, Japan., Yano S; Department of Respiratory Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan., Okumura F; Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan., Matsumoto S; Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan., Shimokawa M; Department of Biostatistics, Yamaguchi University Graduate School of Medicine, Ube, Japan., Seto T; Department of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan., Goto K; Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

المصدر: International journal of clinical oncology [Int J Clin Oncol] 2024 Aug; Vol. 29 (8), pp. 1142-1151. Date of Electronic Publication: 2024 May 17.

نوع المنشور: Journal Article; Clinical Trial, Phase II

بيانات الدورية: Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 9616295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7772 (Electronic) Linking ISSN: 13419625 NLM ISO Abbreviation: Int J Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Crizotinib*/therapeutic use , Proto-Oncogene Proteins c-met*/genetics , Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Mutation*, Humans ; Female ; Middle Aged ; Male ; Aged ; Adult ; Protein Kinase Inhibitors/therapeutic use ; Protein Kinase Inhibitors/adverse effects ; Japan ; Progression-Free Survival ; Exons ; East Asian People

المؤلفون: Wang J; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, PR China., Xu XY; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, PR China., Li XY; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, PR China., Luo JC; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, PR China., Zhang ZY; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, PR China., Chen J; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, PR China., Cai JP; The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China.. Electronic address: caijp61@vip.sina.com., Zhang LK; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, PR China. Electronic address: zlk494411708@163.com., Qian JC; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, PR China. Electronic address: qianjc@wmu.edu.cn.

المصدر: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2024 Aug; Vol. 489, pp. 117016. Date of Electronic Publication: 2024 Jun 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Crizotinib*/pharmacokinetics , Cytochrome P-450 CYP3A*/genetics , Cytochrome P-450 CYP3A*/metabolism , Rats, Sprague-Dawley* , Drug Interactions* , Microsomes, Liver*/metabolism , Microsomes, Liver*/enzymology , Microsomes, Liver*/drug effects , Polymorphism, Genetic*, Animals ; Humans ; Male ; Rats ; Pyridines/pharmacokinetics ; Pyrazoles/pharmacokinetics ; Pyrazoles/pharmacology

المؤلفون: Santiago-O'Farrill JM; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Blessing Bollu A; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yang H; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Orellana V; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Pina M; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang X; Department of Pathology/Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Liu J; Department of Pathology/Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Bast RC Jr; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lu Z; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2024 Sep 04; Vol. 22 (9), pp. 840-851.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Crizotinib*/pharmacology , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/pathology , Ovarian Neoplasms*/genetics , Autophagy*/drug effects , Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Xenograft Model Antitumor Assays*, Humans ; Female ; Animals ; Mice ; Cell Line, Tumor ; Phthalazines/pharmacology ; Piperazines/pharmacology

المؤلفون: Akane Y; Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan., Yamamoto M; Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan., Takebayashi A; Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan., Hamada R; Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan., Igarashi K; Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan., Emori M; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan., Sugita S; Department of Surgical Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan., Takada K; Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Japan., Hasegawa T; Department of Surgical Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan., Tsugawa T; Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan.

المصدر: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Sep; Vol. 71 (9), pp. e31148. Date of Electronic Publication: 2024 Jun 17.

نوع المنشور: Case Reports; Letter

بيانات الدورية: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Crizotinib*/therapeutic use , Rhabdomyosarcoma, Embryonal*/drug therapy , Rhabdomyosarcoma, Embryonal*/genetics , Rhabdomyosarcoma, Embryonal*/pathology , Anaplastic Lymphoma Kinase*/genetics , Oncogene Proteins, Fusion*/genetics, Humans ; Male ; Protein Kinase Inhibitors/therapeutic use ; Female ; Infant, Newborn ; Receptor Protein-Tyrosine Kinases/genetics