المؤلفون: Jane A. Mitchell, Ricky Vaja, Blerina Ahmetaj-Shala, Nicholas S. Kirkby, Peter M. George, Santosh S. Atanur

المساهمون: British Heart Foundation

المصدر: JACC: Basic to Translational Science

مصطلحات موضوعية: 0301 basic medicine, Cardiac & Cardiovascular Systems, Endothelium, ACE2, CTSB, cathepsin B, Inflammation, 030204 cardiovascular system & hematology, medicine.disease_cause, PPIA, peptidylprolyl isomerase A, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, INFLAMMATION, INFECTION, medicine, ADAM17, ADAM metallopeptidase domain 17, Respiratory system, 1102 Cardiorespiratory Medicine and Haematology, PPIB, peptidylprolyl isomerase B, Coronavirus, Peptidylprolyl isomerase, Science & Technology, ACE2, angiotensin converting enzyme 2, COVID-19, coronavirus disease-2019, business.industry, cardiovascular, GTEx, Genotype-Tissue Expression, SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2, COVID-19, 1103 Clinical Sciences, BSG, basigin, endothelial cells, Epithelium, CTSL, cathepsin L, 030104 developmental biology, medicine.anatomical_structure, age, PBMC, peripheral blood mononuclear cells, Basigin, Immunology, Cardiovascular System & Cardiology, CD147, TMPRSS2, transmembrane serine protease 2, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Life Sciences & Biomedicine, SYSTEM

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac3c81f45036514a8b648435b093b0b
https://doi.org/10.1016/j.jacbts.2020.09.010

المؤلفون: Charles Nicaise, Kevin Willemart, Florian Poulain, Nicolas Gillet, Noémie Avalosse, Riselane Lotfi, Jacques Gilloteaux, Noelle Ninanne, Noémie Lejeune, Kathleen De Swert, Valery Bielarz

المصدر: Brain Research
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344

مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, viruses, Cell, Neuroblastoma, 0302 clinical medicine, RA, retinoic acid, tmprss2, transmembrane protease, serine 2, BBB, blood–brain barrier, Cytopathic effect, COVID-19, coronavirus disease 2019, ctsb, cathepsin B, General Neuroscience, Serine Endopeptidases, ish, in situ hybridization, medicine.anatomical_structure, Neurotropism, Angiotensin-Converting Enzyme 2, Cell type, SARS-CoV, severe acute respiratory syndrome coronavirus, Clinical Neurology, Biology, Models, Biological, Article, ctsl, cathepsin L, MOI, multiplicity-of-infection, 03 medical and health sciences, Downregulation and upregulation, Cell Line, Tumor, medicine, Humans, Molecular Biology, Tropism, hprt, hypoxanthine–guanine phosphoribosyltransferase, SARS-CoV-2, ace2, angiotensin-converting enzyme 2, COVID-19, medicine.disease, Molecular biology, 030104 developmental biology, Cell culture, Susceptibility, Vero cell, Neurology (clinical), Glioblastoma, 030217 neurology & neurosurgery, SARS-CoV-2, severe acute respiratory syndrome coronavirus-2, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6b19eec2e5f936a29312b7975f27ca
https://researchportal.unamur.be/en/publications/b4334368-1063-4325-9db9-a5dc776e2c12

المؤلفون: Jeganathan Manivannan, Lakshmikirupa Sundaresan

المصدر: Gene Reports

مصطلحات موضوعية: IL-17, interleukin-17, Exposome, PTM, post-translational modification, Proteome, Pathway analysis, Microarray, TMPRSS2, transmembrane protease, serine 2, CTSB, cathepsin B, Omics, RNA-Seq, Biology, PM, particulate matter, ACE2, angiotensin-converting enzyme 2, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Interactome, Article, PPAR, peroxisome proliferator-activated receptors, PPI, protein-protein interaction, Transcriptome, Pathogenesis, GSEA, gene set enrichment analysis, DEG, differentially expressed genes, X2K, eXpression2Kinases, Genetics, GEO, Gene Expression Omnibus, COVID19, coronavirus disease 2019, TNF, tumor necrosis factor, COVID-19, VEGF, vascular endothelial growth factor, CTSL, cathepsin L, Immunology, RNA-seq, Particulate matter, TLR, Toll-like receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e60ca6165e24941ea13af5b9061bd3
https://doi.org/10.1016/j.genrep.2021.101312

المؤلفون: Anthony P. Davenport, H. Llewelyn Roderick, Emma L. Robinson, Kanar Alkass, Janet J. Maguire, Olaf Bergmann

المساهمون: Cardiologie, RS: Carim - H02 Cardiomyopathy, Maguire, Janet [0000-0002-9254-7040], Davenport, Anthony [0000-0002-2096-3117], Apollo - University of Cambridge Repository

المصدر: Journal of Molecular and Cellular Cardiology, 147, 88-91. ELSEVIER SCI LTD
Journal of Molecular and Cellular Cardiology

مصطلحات موضوعية: 0301 basic medicine, Aging, Cathepsin L, ACE, angiotensin I converting enzyme, Disease, 030204 cardiovascular system & hematology, BDKRB2, bradykinin receptor B2, ComputingMethodologies_ARTIFICIALINTELLIGENCE, Cathepsin B, Angiotensin, 0302 clinical medicine, Interferon, MAS1, MAS1 proto-oncogene G protein-coupled receptor, Medicine, TMPRSS11D, transmembrane protease serine 11D, Myocytes, Cardiac, TMPRSS2, transmembrane protease serine 2, Young adult, Furin, IFNAR1, interferon (alpha beta and omega) receptor 1, biology, Serine Endopeptidases, Interleukin, AGTR1, angiotensin II receptor type 1, Apelin, BDKRB1, bradykinin receptor B1, apelin, Interferon gamma receptor 1, TMPRSS11E, transmembrane protease serine 11E, Angiotensin-Converting Enzyme 2, Cardiology and Cardiovascular Medicine, Coronavirus Infections, medicine.drug, Angiotensins, InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL, Pneumonia, Viral, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, RNA-sequencing, CTSB, cathepsin B, Virus Attachment, APLNR, apelin receptor, IRF1, interferon regulatory factor 1 (regulates transcription of interferons), Peptidyl-Dipeptidase A, Bradykinin, FURIN, furin (paired basic amino acid cleaving enzyme), TMPRSS2, Article, 03 medical and health sciences, Betacoronavirus, Downregulation and upregulation, Humans, ADAM17, ADAM metallopeptidase domain 17, IL6R, interleukin 6 receptor, Molecular Biology, Pandemics, Gene, ComputingMethodologies_COMPUTERGRAPHICS, SLC6A19, solute carrier family 6 (neutral amino acid transporter) member 19 (aka B0AT1), SARS-CoV-2, business.industry, Myocardium, human cardiomyocytes, IFNAR2, interferon (alpha beta and omega) receptor 2 (IFNAR1and 2 form chains for interferons alpha and beta), COVID-19, Virus Internalization, angiotensin, CTSL, cathepsin L, ComputingMethodologies_PATTERNRECOGNITION, 030104 developmental biology, Immunology, biology.protein, IFNGR1, Interferon gamma receptor 1, Human cardiomyocytes, ACE2, angiotensin I converting enzyme 2, business

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f95f476673d68f64444c4caae84f8cf
https://doi.org/10.1101/2020.07.07.191429

المؤلفون: Mennatullah El-Nadi, Eyyad Nassar, Burkhard Greve, Hebatallah Hassan, Yahia M. Ismail, Sherif Abdelaziz Ibrahim, Mohamed El-Shinawi, Moshira Ezzat Saleh, Mahmoud Amer, Martin Götte

المصدر: Matrix Biology Plus
Matrix Biology Plus, Vol 6, Iss, Pp 100030-(2020)

مصطلحات موضوعية: ER, estrogen receptor, Cathepsin L, TNF-α, tumor necrosis factor-α, Biochemistry, Pathogenesis, 0302 clinical medicine, Invasion, HPSE, heparanase, skin and connective tissue diseases, lcsh:QH301-705.5, 0303 health sciences, CD163+ M2-type tumor-associated macrophages, biology, qPCR, quantitative real-time PCR, MTT, 3-(4,5-dimethyl-2-yl)-2,5-diphenyltetrazolium bromide, ECM, extracellular matrix, 3. Good health, OGT 2115, 2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid, Interleukin 10, 030220 oncology & carcinogenesis, IL-10, Inflammatory Breast Carcinoma, IRB, Institutional Review Board, Triple negative subtype, Histology, Biophysics, FFPE, Formalin-Fixed Paraffin-Embedded, Inflammatory breast cancer, Article, 03 medical and health sciences, Breast cancer, TAMs, tumor-associated macrophages, Genetics, medicine, TN, triple negative, Heparanase, Molecular Biology, 030304 developmental biology, HSPGs, heparan sulfate proteoglycans, business.industry, rh IL-10, recombinant human interleukin-10, PR, progesterone receptor, Cell Biology, IBC, inflammatory breast cancer, medicine.disease, HER-2, human epidermal growth factor receptor-2, CTSL, cathepsin L, lcsh:Biology (General), MMP2, matrix metalloproteinase2, biology.protein, Cancer research, business, CD163

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be276262e2e607a20100873b99492bf

المصدر: Autophagy

مصطلحات موضوعية: GPN, glycyl-l-phenylalanine 2-naphthylamide, MTOR, mechanistic target of rapamycin, Cell Survival, Green Fluorescent Proteins, CQ, chloroquine, CTSB, cathepsin B, Heterocyclic Compounds, 4 or More Rings, Inhibitory Concentration 50, RFP, red fluorescent protein, vacuolin-1, lysosomes, Microscopy, Electron, Transmission, ATG, autophagy-related, Phagosomes, Leup, leupeptin, tfLC3, tandem fluorescence-tagged LC3, Autophagy, LAMP1, lysosomal-associated membrane protein 1, Homeostasis, Humans, MAP1LC3, microtubule-associated protein 1 light chain 3, Cell Proliferation, rab5 GTP-Binding Proteins, GFP, green fluorescent protein, Adenosine Triphosphatases, pH, BAF, bafilomycin A1, Lentivirus, RAB5A, Chloroquine, Hep G2 Cells, Hydrogen-Ion Concentration, EGFR, epidermal growth factor receptor, CTSL, cathepsin L, Metabolism, endosomes, Mutation, Calcium, Brief Reports, Corrigendum, autophagosomes, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::139bbe20d0579621c443886f6b01ff49
https://pubmed.ncbi.nlm.nih.gov/25483964

المؤلفون: Zhanggui Wang, Xinbing Sui, Liangkun You, Jiansheng Xie, Zhao Jing, Hongsen Li, Jiawei Shou, Hongming Pan, Weidong Han

المصدر: Autophagy

مصطلحات موضوعية: ATF4, activating transcription factor 4, NES, nuclear export signal, ConA, concanavalin A, Cellular homeostasis, Review, Stat3 Signaling Pathway, STAT3, BNIP3, BCL2/adenovirus E1B 19kDa interacting protein 3, EIF2A, eukaryotic initiation factor 2A, 65kDa, Neoplasms, ALK, anaplastic lymphoma receptor tyrosine kinase, miRNA, microRNA, Mitophagy, FOXO1/3, forkhead box O1/3, RTK, receptor tyrosine kinases, receptor tyrosine kinases, PTPN6, protein tyrosine phosphatase, non-receptor type 6, BECN1, targeted therapy, CuB, cucurbitacin B, Mitochondria, Cell biology, STAT3, signal transducer and activator of transcription 3 (acute-phase response factor), COX8, cytochrome c oxidase subunit VIII, PDGFRB, platelet-derived growth factor receptor, β polypeptide, IMM, inner mitochondrial membrane, Subcellular Fractions, CNTF, ciliary neurotrophic factor, STAT3 Transcription Factor, KDR, kinase insert domain receptor, autophagy, MMP14, matrix metallopeptidase 14 (membrane-inserted), Programmed cell death, Cell signaling, MLS, mitochondrial localization sequence, PTPN2, protein tyrosine phosphatase, non-receptor type 2, IL6, interleukin 6, ETC, electron transport chain, HIF1A, hypoxia inducible factor 1, α subunit (basic helix-loop-helix transcription factor), VHL, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase, CTSB, cathepsin B, NFKB1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, Biology, BAG3, Models, Biological, ER, endoplasmic reticulum, XPO1, exportin 1, ROS, reactive oxygen species, MAPK1, mitogen-activated protein kinase 1, SH2, src homology 2, Animals, Humans, cancer, PRKAA2, protein kinase, AMP-activated, α 2 catalytic subunit, Molecular Biology, EIF2AK2, eukaryotic translation initiation factor 2-α kinase 2, EGF, epidermal growth factor, PTPN11, protein tyrosine phosphatase, non-receptor type 11, Autophagy, HDAC3, histone deacetylase 3, NDUFA13, NADH dehydrogenase (ubiquinone) 1 α subcomplex, 13, Cell Biology, LMP, lysosomal membrane permeabilization, CTSL, cathepsin L, mitophagy, NLS, nuclear localization signal, mitoSTAT3, mitochondrial STAT3, Cancer research, CYCS, cytochrome c, somatic, MAP1LC3A, microtubule-associated protein 1 light chain 3 α

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7370b1766f56b7801df377b10de63140
https://doi.org/10.1080/15548627.2015.1017192

المؤلفون: Maria Dominguez, Issidora S. Papassideri, Aimilia D. Sklirou, Marianna Ralli, Ioannis P. Trougakos, Alexios-Leandros Skaltsounis

المصدر: Redox Biology
Redox Biology, Vol 5, Iss, Pp 205-215 (2015)

مصطلحات موضوعية: Antioxidant responses, Sqstm1, sequestosome 1, Clinical Biochemistry, Cell, PDR, proteome damage responses, Chaperone, hdac6, histone deacetylase 6, Biochemistry, Antioxidants, Cell Movement, hsf1, heat shock transcription factor-1, lcsh:QH301-705.5, Cellular Senescence, lcsh:R5-920, BECN1, Keap1, Kelch-like ECH-associated protein 1, medicine.anatomical_structure, ctsd, cathepsin-D, HDFs, human diploid fibroblasts, Matrix Metalloproteinase 9, Nqo1, NAD(P)H dehydrogenase, quinone 1, Matrix Metalloproteinase 2, lcsh:Medicine (General), Oligopeptides, Nrf2, NF-E2-related factor 2, Research Paper, ALS, autophagy lysosome system, Senescence, Proteasome Endopeptidase Complex, Cell Survival, NF-E2-Related Factor 2, Human fibroblasts, Biology, Hexapeptide-11, Cell Line, ER, endoplasmic reticulum, ROS, reactive oxygen species, UPS, ubiquitin proteasome system, Extracellular, medicine, Autophagy, CLU, apolipoprotein J/Clusterin, Humans, Viability assay, ctsl, cathepsin-L, Txnrd1, thioredoxin reductase 1, hsp, heat shock protein, Proteasome, Organic Chemistry, PN, proteostasis network, Fibroblasts, KEAP1, Diploidy, Oxidative Stress, Proteostasis, lcsh:Biology (General), becn1, beclin-1, Molecular Chaperones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21d891c4db690600e8c356f78ea8f22
https://pubmed.ncbi.nlm.nih.gov/25974626

المؤلفون: Manivannan J; Environmental Health and Toxicology Lab, Department of Environmental Sciences, School of Life Sciences, Bharathiar University, Coimbatore 641046, Tamil Nadu, India., Sundaresan L; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.

المصدر: Gene reports [Gene Rep] 2021 Dec; Vol. 25, pp. 101312. Date of Electronic Publication: 2021 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101680713 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2452-0144 (Print) Linking ISSN: 24520144 NLM ISO Abbreviation: Gene Rep Subsets: PubMed not MEDLINE

المؤلفون: Ahmetaj-Shala B; Cardiorespiratory Interface, National Heart and Lung Institute, Imperial College London, London, United Kingdom., Vaja R; Cardiorespiratory Interface, National Heart and Lung Institute, Imperial College London, London, United Kingdom., Atanur SS; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom.; Institute of Translational Medicine and Therapeutics, Data Science Group, National Institute for Health Research, Biomedical Research Centre, Imperial College London, London, United Kingdom., George PM; Cardiorespiratory Interface, National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Interstitial Lung Disease Unit, National Heart and Lung Institute, Imperial College London, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom., Kirkby NS; Cardiorespiratory Interface, National Heart and Lung Institute, Imperial College London, London, United Kingdom., Mitchell JA; Cardiorespiratory Interface, National Heart and Lung Institute, Imperial College London, London, United Kingdom.

المصدر: JACC. Basic to translational science [JACC Basic Transl Sci] 2020 Nov; Vol. 5 (11), pp. 1111-1123. Date of Electronic Publication: 2020 Oct 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier on behalf of the American College of Cardiology Foundation Country of Publication: United States NLM ID: 101677259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2452-302X (Electronic) Linking ISSN: 2452302X NLM ISO Abbreviation: JACC Basic Transl Sci Subsets: PubMed not MEDLINE