المؤلفون: Dai D. Nghiem

المصدر: Uro, Vol 1, Iss 4, Pp 222-227 (2021)

مصطلحات موضوعية: tacrolimus toxicity, organ failure, pharmacologic therapy, cytochrome P450-3A, phenytoin, metabolic enhancement, Diseases of the genitourinary system. Urology, RC870-923

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2673-4397/1/4/24; https://doaj.org/toc/2673-4397

URL الوصول: https://doaj.org/article/21f71f5da1574a1d931f2d06d8031fda

المؤلفون: Yaogeng Wang, Rolf W. Sparidans, Sander Potters, Rahime Şentürk, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

المصدر: Pharmaceuticals, Vol 14, Iss 11, p 1087 (2021)

مصطلحات موضوعية: selpercatinib, cytochrome P450-3A, oral exposure, rearranged during transfection (RET) receptor kinase, Slco1a/1b, p-glycoprotein/ABCB1, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/14/11/1087; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/a3ac2265932f41afa84cd9b41d33fe43

المؤلفون: Wenlong Li, Rolf W. Sparidans, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

المصدر: Pharmaceutics, Vol 13, Iss 11, p 1761 (2021)

مصطلحات موضوعية: repotrectinib (TPX-0005), P-glycoprotein, breast cancer resistance protein, brain accumulation, organic anion transporting polypeptides, cytochrome P450-3A, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/13/11/1761; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/96586ee99982471e86dd47f36c4d54e8

المؤلفون: Li, Wenlong, Lehutova, Daniela, Sparidans, Rolf W, Heydari, Paniz, Wang, Jing, Lebre, Maria C, Beijnen, Jos H, Schinkel, Alfred H, Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المصدر: European Journal of Pharmaceutics and Biopharmaceutics, 177, 135. Elsevier

مصطلحات موضوعية: Mice, Knockout, ATP Binding Cassette Transporter, Subfamily B, Organic anion transporting polypeptides, Pharmaceutical Science, Brain, Organic Anion Transporters, P-glycoprotein/ABCB1, General Medicine, Nuclear Receptor Subfamily 1, Group F, Member 3, Cintirorgon, Benzoxazines, Madin Darby Canine Kidney Cells, Oral availability, Mice, Dogs, Brain accumulation, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Cytochrome P-450 CYP3A, Humans, Propionates, Cytochrome P450-3A, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7d98d2e1804d34f5f1bbeb20c569f6
https://dspace.library.uu.nl/handle/1874/421926

المؤلفون: Li, Wenlong, Sparidans, Rolf W., Lebre, Maria C., Beijnen, Jos H., Schinkel, Alfred H., Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المصدر: Pharmaceutics
Volume 13
Issue 11
Pharmaceutics, 13(11), 1. American Chemical Society
Pharmaceutics, Vol 13, Iss 1761, p 1761 (2021)

مصطلحات موضوعية: Genetically modified mouse, animal structures, CYP3A, medicine.drug_class, Pharmaceutical Science, Pharmacology, P-glycoprotein, repotrectinib (TPX-0005), Article, Oral availability, Pharmacy and materia medica, Brain accumulation, medicine, cytochrome P450-3A, Repotrectinib (TPX-0005), organic anion transporting polypeptides, biology, Chemistry, Organic anion transporting polypeptides, Transporter, Breast cancer resistance protein, RS1-441, ALK inhibitor, brain accumulation, oral availability, Trk receptor, breast cancer resistance protein, Toxicity, embryonic structures, biology.protein, Efflux, sense organs, Cytochrome P450-3A

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f39cc628910e18afa3cb91fdf8477f
http://europepmc.org/articles/PMC8619046

المؤلفون: Wang, Yaogeng, Sparidans, Rolf W., Potters, Sander, Şentürk, Rahime, Lebre, Maria C., Beijnen, Jos H., Schinkel, Alfred H., Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المصدر: Pharmaceuticals
Pharmaceuticals, Vol 14, Iss 1087, p 1087 (2021)
Volume 14
Issue 11
Pharmaceuticals, 14(11), 1. MDPI AG

مصطلحات موضوعية: Genetically modified mouse, Abcg2, CYP3A, Transgene, Pharmaceutical Science, Pharmacology, Article, Pharmacy and materia medica, Pharmacokinetics, In vivo, Brain accumulation, Drug Discovery, cytochrome P450-3A, Rearranged during transfection (RET) receptor kinase, biology, CYP3A4, Chemistry, P-glycoprotein/ABCB1, In vitro, RS1-441, brain accumulation, Slco1a/1b, p-glycoprotein/ABCB1, biology.protein, rearranged during transfection (RET) receptor kinase, Medicine, Molecular Medicine, Cytochrome P450-3A, Oral exposure, Selpercatinib, selpercatinib, oral exposure

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577da9c135f79f3cbbd2413a656ce1d4
https://pubmed.ncbi.nlm.nih.gov/34832869

المؤلفون: Li, Wenlong, Tibben, Matthijs, Wang, Yaogeng, Lebre, Maria C, Rosing, Hilde, Beijnen, Jos H, Schinkel, Alfred H, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

المصدر: International Journal of Cancer, 146(6), 1631. Wiley-Liss Inc.

مصطلحات موضوعية: Genetically modified mouse, Cancer Research, ATP Binding Cassette Transporter, Subfamily B, Abcg2, CYP3A, Herb-Drug Interactions, Organic Anion Transporters, P-glycoprotein, Pharmacology, Madin Darby Canine Kidney Cells, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, Pharmacokinetics, Transforming Growth Factor beta, Tetrahydroisoquinolines, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Cytochrome P-450 CYP3A, Humans, Galunisertib, Tissue Distribution, cytochrome P450-3A, Receptor, biology, CYP3A4, Chemistry, Brain, Oatp1a/1b, Neoplasm Proteins, brain accumulation, galunisertib, Oncology, oral availability, 030220 oncology & carcinogenesis, Quinolines, biology.protein, Acridines, Pyrazoles, Female, intestinal disposition, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce90e3ddebbd0e2bc1b7872e31bd5917
https://doi.org/10.1002/ijc.32568

المؤلفون: Wang, Yaogeng, Sparidans, Rolf W, Wang, Jing, Li, Wenlong, Lebre, Maria C, Beijnen, Jos H, Schinkel, Alfred H, Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المصدر: European Journal of Pharmaceutics and Biopharmaceutics, 170, 197. Elsevier

مصطلحات موضوعية: Male, Ritonavir, Elacridar, OATP1A, Administration, Oral, Biological Availability, Brain, Pharmaceutical Science, Drug Synergism, Mice, Inbred Strains, ABCB1, General Medicine, Oral availability, Mice, Pyrimidines, Tandem Mass Spectrometry, Tetrahydroisoquinolines, Acridines, Animals, Pyrazoles, Rifampin, Cytochrome P450-3A, Larotrectinib, Chromatography, Liquid, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a32468337a0ad78f59ea2f040e76f1
https://hdl.handle.net/1874/417732

المؤلفون: Li, Wenlong, Tibben, Matthijs, Wang, Yaogeng, Lebre, Maria C, Rosing, Hilde, Beijnen, Jos H, Schinkel, Alfred H

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

مصطلحات موضوعية: brain accumulation, galunisertib, oral availability, intestinal disposition, cytochrome P450-3A, P-glycoprotein, Oatp1a/1b

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______101::0ce757aa7128ed40489d273e65870d47
https://dspace.library.uu.nl/handle/1874/390157

المؤلفون: Wang, Yaogeng, Sparidans, Rolf W, Potters, Sander, Lebre, Maria C, Beijnen, Jos H, Schinkel, Alfred H, Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Pharmacology

المصدر: Pharmacological Research, 172, 1. Academic Press Inc.

مصطلحات موضوعية: Male, Genetically modified mouse, 3081361) [Vandetanib (PubChem CID], Pyridines, CYP3A, Administration, Oral, Biological Availability, Organic Anion Transporters, Antineoplastic Agents, Elacridar (PubChem CID: 119373), Pharmacology, BCRP/ABCG2, Oral availability, Pharmacokinetics, In vivo, Brain accumulation, Testis, Pralsetinib (PubChem CID: 129073603), 129073603) [Pralsetinib (PubChem CID], Animals, Cytochrome P-450 CYP3A, Distribution (pharmacology), Protein Kinase Inhibitors, 134436906) [Selpercatinib (PubChem CID], Mice, Knockout, CYP3A4, Pralsetinib, 119373) [Elacridar (PubChem CID], Chemistry, 3036703) [Zosuquidar (PubChem CID], Proto-Oncogene Proteins c-ret, Brain, P-glycoprotein/ABCB1, 25102847) [Cabozantinib (PubChem CID], Penetration (firestop), Cabozantinib (PubChem CID: 25102847), In vitro, Pyrimidines, Pyrazoles, Vandetanib (PubChem CID: 3081361), Female, Cytochrome P450-3A, Zosuquidar (PubChem CID: 3036703), Selpercatinib (PubChem CID: 134436906)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af836f8c0f0ffc2be19ee4377fa0acec
https://doi.org/10.1016/j.phrs.2021.105850