المؤلفون: Yoshizaki K; Laboratory of Experimental Environmental Pathology, Department of Pathology, São Paulo University Medical School, São Paulo, Brazil., Frias DP; Laboratory of Experimental Environmental Pathology, Department of Pathology, São Paulo University Medical School, São Paulo, Brazil., Maier K; Laboratory of Experimental Environmental Pathology, Department of Pathology, São Paulo University Medical School, São Paulo, Brazil., Smelan J; Laboratory of Experimental Environmental Pathology, Department of Pathology, São Paulo University Medical School, São Paulo, Brazil., Correia AT; Thoracic Surgery Division, Department of Cardiopneumology, InCor, Clinics Hospital, School of Medicine, University of São Paulo, São Paulo, Brazil., Oliveira LMDS; Laboratory of Medical Investigation in Dermatology and Immunodeficiences, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Amato-Lourenço LF; Laboratory of Experimental Environmental Pathology, Department of Pathology, São Paulo University Medical School, São Paulo, Brazil.; Institute of Advanced Studies (IEA) Global Cities Program, University of São Paulo, São Paulo, Brazil., Santillo BT; Laboratory of Medical Investigation in Dermatology and Immunodeficiences, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Prado CM; Federal University of São Paulo, Santos, Brazil., Oshiro TM; Laboratory of Medical Investigation in Dermatology and Immunodeficiences, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Barbuto JAM; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Mauad T; Laboratory of Experimental Environmental Pathology, Department of Pathology, São Paulo University Medical School, São Paulo, Brazil., Macchione M; Laboratory of Experimental Environmental Pathology, Department of Pathology, São Paulo University Medical School, São Paulo, Brazil.

المصدر: Journal of applied toxicology : JAT [J Appl Toxicol] 2024 Sep; Vol. 44 (9), pp. 1317-1328. Date of Electronic Publication: 2024 May 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1263 (Electronic) Linking ISSN: 0260437X NLM ISO Abbreviation: J Appl Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Coculture Techniques* , Cytokines*/metabolism , Dendritic Cells*/drug effects , Dendritic Cells*/metabolism , Cytochrome P-450 Enzyme System*/metabolism , Cytochrome P-450 Enzyme System*/genetics , Propanols*/toxicity , Propanols*/metabolism, Humans ; Cell Line ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1B1/genetics ; Cytochrome P-450 CYP1B1/metabolism ; Perfume/toxicity ; Receptors, Aryl Hydrocarbon/metabolism ; Receptors, Aryl Hydrocarbon/genetics ; Cytochrome P-450 CYP1A2/metabolism ; Cytochrome P-450 CYP1A2/genetics

المؤلفون: Elbarbry FA; School of Pharmacy, Pacific University, 222 SE 8th Ave., Hillsboro, OR, 97123, USA. Fawzy.elbarbry@pacificu.edu., Ibrahim TM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, P.O. Box 33516, Kafrelsheikh, Egypt., Abdelrahman MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, 11829, Egypt., Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, 50019, Sesto Fiorentino, Firenze, Italy., Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, P.O. Box 33516, Kafrelsheikh, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University, Alexandria, Egypt.

المصدر: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2024 Sep; Vol. 49 (5), pp. 583-594. Date of Electronic Publication: 2024 Jun 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: Carbonic Anhydrase Inhibitors*/pharmacology , Carbonic Anhydrase Inhibitors*/chemistry , Coumarins*/pharmacology , Coumarins*/chemistry , Molecular Docking Simulation* , Cytochrome P-450 Enzyme Inhibitors*/pharmacology , Cytochrome P-450 Enzyme System*/metabolism, Humans ; Sulfonamides/pharmacology ; Sulfonamides/chemistry ; Cytochrome P-450 CYP2A6/metabolism ; Cytochrome P-450 CYP2A6/antagonists & inhibitors

المؤلفون: Magliocca M; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Berger B; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Lemoine V; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Kaufmann P; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

المصدر: Journal of clinical pharmacology [J Clin Pharmacol] 2024 Sep; Vol. 64 (9), pp. 1123-1129. Date of Electronic Publication: 2024 May 26.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP3A*/metabolism , Cytochrome P-450 CYP3A Inhibitors*/administration & dosage , Cytochrome P-450 CYP3A Inhibitors*/pharmacokinetics , Drug Interactions* , Midazolam*/administration & dosage , Midazolam*/analogs & derivatives , Midazolam*/pharmacokinetics, Humans ; Cytochrome P-450 CYP3A Inducers/administration & dosage ; Cytochrome P-450 CYP3A Inducers/pharmacokinetics ; Drugs, Investigational/administration & dosage ; Drugs, Investigational/pharmacokinetics

المؤلفون: Xue Y; Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol-Myers Squibb, Princeton, New Jersey (Y.X., L.W., R.H., B.M., A.G., J.X.S.); Regeneron Pharmaceuticals Inc., Tarrytown, New York (M.C.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey (K.D.) yongjun.xue@bms.com., Wang L; Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol-Myers Squibb, Princeton, New Jersey (Y.X., L.W., R.H., B.M., A.G., J.X.S.); Regeneron Pharmaceuticals Inc., Tarrytown, New York (M.C.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey (K.D.)., Huo R; Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol-Myers Squibb, Princeton, New Jersey (Y.X., L.W., R.H., B.M., A.G., J.X.S.); Regeneron Pharmaceuticals Inc., Tarrytown, New York (M.C.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey (K.D.)., Chen M; Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol-Myers Squibb, Princeton, New Jersey (Y.X., L.W., R.H., B.M., A.G., J.X.S.); Regeneron Pharmaceuticals Inc., Tarrytown, New York (M.C.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey (K.D.)., Melo B; Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol-Myers Squibb, Princeton, New Jersey (Y.X., L.W., R.H., B.M., A.G., J.X.S.); Regeneron Pharmaceuticals Inc., Tarrytown, New York (M.C.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey (K.D.)., Dingley K; Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol-Myers Squibb, Princeton, New Jersey (Y.X., L.W., R.H., B.M., A.G., J.X.S.); Regeneron Pharmaceuticals Inc., Tarrytown, New York (M.C.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey (K.D.)., Gaudy A; Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol-Myers Squibb, Princeton, New Jersey (Y.X., L.W., R.H., B.M., A.G., J.X.S.); Regeneron Pharmaceuticals Inc., Tarrytown, New York (M.C.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey (K.D.)., Shen JX; Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol-Myers Squibb, Princeton, New Jersey (Y.X., L.W., R.H., B.M., A.G., J.X.S.); Regeneron Pharmaceuticals Inc., Tarrytown, New York (M.C.); and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey (K.D.).

المصدر: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2024 Aug 14; Vol. 52 (9), pp. 966-974. Date of Electronic Publication: 2024 Aug 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP3A*/metabolism , Drug Interactions* , Biomarkers*/blood , Deoxycholic Acid*/blood , Cytochrome P-450 CYP3A Inducers*/pharmacology , Hydroxycholesterols*/blood, Humans ; Tandem Mass Spectrometry/methods ; Male ; Adult ; Rifampin/pharmacology ; Rifampin/blood ; Cytochrome P-450 CYP3A Inhibitors/pharmacology ; Cytochrome P-450 CYP3A Inhibitors/pharmacokinetics ; Chromatography, Liquid/methods ; Taurine/blood ; Taurine/analogs & derivatives

المؤلفون: Kovar C; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany., Loer HLH; Clinical Pharmacy, Saarland University, Saarbrücken, Germany., Rüdesheim S; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany., Fuhr LM; Clinical Pharmacy, Saarland University, Saarbrücken, Germany., Marok FZ; Clinical Pharmacy, Saarland University, Saarbrücken, Germany., Selzer D; Clinical Pharmacy, Saarland University, Saarbrücken, Germany., Schwab M; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Departments of Clinical Pharmacology, and Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC2180), Image-Guided and Functionally Instructed Tumor Therapies, University of Tübingen, Tübingen, Germany., Lehr T; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.

المصدر: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jul; Vol. 13 (7), pp. 1144-1159. Date of Electronic Publication: 2024 May 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Dasatinib*/pharmacokinetics , Dasatinib*/administration & dosage , Dasatinib*/pharmacology , Drug Interactions* , Cytochrome P-450 CYP3A Inhibitors*/pharmacology , Cytochrome P-450 CYP3A Inhibitors*/pharmacokinetics , Cytochrome P-450 CYP3A Inhibitors*/administration & dosage , Models, Biological* , Protein Kinase Inhibitors*/pharmacokinetics , Protein Kinase Inhibitors*/administration & dosage, Humans ; Cytochrome P-450 CYP3A Inducers/pharmacology ; Cytochrome P-450 CYP3A Inducers/administration & dosage ; Cytochrome P-450 CYP3A/metabolism ; Male ; Adult ; Area Under Curve ; Female ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/administration & dosage ; Middle Aged

المؤلفون: Uno Y; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima City, Kagoshima, Japan (Y.U., K.T.-K.); Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan (M.I.); Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan (H.M.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (N.M., H.Y.) unoxx001@vet.kagoshima-u.ac.jp hyamazak@ac.shoyaku.ac.jp., Tsukiyama-Kohara K; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima City, Kagoshima, Japan (Y.U., K.T.-K.); Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan (M.I.); Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan (H.M.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (N.M., H.Y.)., Ishizuka M; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima City, Kagoshima, Japan (Y.U., K.T.-K.); Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan (M.I.); Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan (H.M.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (N.M., H.Y.)., Mizukawa H; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima City, Kagoshima, Japan (Y.U., K.T.-K.); Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan (M.I.); Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan (H.M.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (N.M., H.Y.)., Murayama N; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima City, Kagoshima, Japan (Y.U., K.T.-K.); Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan (M.I.); Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan (H.M.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (N.M., H.Y.)., Yamazaki H; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima City, Kagoshima, Japan (Y.U., K.T.-K.); Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan (M.I.); Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, Japan (H.M.); and Showa Pharmaceutical University, Machida, Tokyo, Japan (N.M., H.Y.) unoxx001@vet.kagoshima-u.ac.jp hyamazak@ac.shoyaku.ac.jp.

المصدر: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2024 Aug 14; Vol. 52 (9), pp. 1009-1019. Date of Electronic Publication: 2024 Aug 14.

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

مواضيع طبية MeSH: Liver*/metabolism , Liver*/enzymology , Cytochrome P-450 CYP4A*/metabolism , Cytochrome P-450 CYP4A*/genetics , Kidney*/metabolism , Amino Acid Sequence* , Tupaiidae*/genetics , Phylogeny*, Animals ; Humans ; Dogs ; Swine ; Cats ; Cytochrome P-450 Enzyme System/metabolism ; Cytochrome P-450 Enzyme System/genetics ; DNA, Complementary/genetics ; Molecular Sequence Data ; Species Specificity

المؤلفون: Jiang T; Department of Civil and Environmental Engineering, Northeastern University, Boston, MA 02115, USA; Department of Environmental and Sustainable Engineering, University at Albany, State University of New York, Albany, NY 12222, USA., Hou L; Department of Civil and Environmental Engineering, Utah State University, Logan, UT 84322, USA; Utah Water Research Laboratory, Utah State University, Logan, UT 84322, USA., Rahman SM; Department of Civil and Environmental Engineering, Northeastern University, Boston, MA 02115, USA; Department of Civil Engineering, Bangladesh University of Engineering and Technology, BUET Central Road, Dhaka 1000, Bangladesh., Gong Z; Department of Materials, Imperial College London, London LND SW7 2AZ, UK., Bai X; Department of Chemistry, The University of Manchester, Manchester M13 9PL, UK., Vulpe C; Department of Physiological Sciences, Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA., Fasullo M; Department of Nanoscale Science and Engineering, University at Albany, State University of New York, Albany, NY 12222, USA., Gu AZ; School of Civil and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA. Electronic address: aprilgu@cornell.edu.

المصدر: Journal of hazardous materials [J Hazard Mater] 2024 Aug 05; Vol. 474, pp. 134850. Date of Electronic Publication: 2024 Jun 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE

مواضيع طبية MeSH: Titanium*/toxicity , Reactive Oxygen Species*/metabolism , Saccharomyces cerevisiae*/drug effects , Saccharomyces cerevisiae*/genetics , Cytochrome P-450 CYP1A1*/genetics , Cytochrome P-450 CYP1A1*/metabolism , DNA Damage* , Mutagenicity Tests*, Humans ; Cytochrome P-450 CYP1A2/genetics ; Cytochrome P-450 CYP1A2/metabolism ; Mutagens/toxicity ; Oxidative Stress/drug effects ; Genes, Reporter ; Nanoparticles/toxicity ; Metal Nanoparticles/toxicity ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism

المؤلفون: Halman A; Cancer Therapies, Stem Cell Medicine, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia., Lunke S; Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Victoria, Australia., Sadedin S; Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia., Moore C; Cancer Therapies, Stem Cell Medicine, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia., Conyers R; Cancer Therapies, Stem Cell Medicine, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.; The Novo Nordisk Foundation Centre for Stem Cell Medicine, ReNEW, Melbourne Node, Parkville, Victoria, Australia.; Children's Cancer Centre, The Royal Children's Hospital, Parkville, Victoria, Australia.

المصدر: Clinical and translational science [Clin Transl Sci] 2024 Aug; Vol. 17 (8), pp. e13911.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

مواضيع طبية MeSH: Benchmarking* , Cytochrome P-450 CYP2D6*/genetics , Pharmacogenetics*/standards , Pharmacogenetics*/methods, Humans ; Cytochrome P-450 CYP2C19/genetics ; Whole Genome Sequencing/standards ; Whole Genome Sequencing/methods ; Genotyping Techniques/methods ; Genotype ; Cytochrome P-450 CYP2C9/genetics ; Cytochrome P-450 CYP2A6/genetics ; Pharmacogenomic Testing/standards ; Pharmacogenomic Testing/methods ; High-Throughput Nucleotide Sequencing/standards ; Vitamin K Epoxide Reductases

المؤلفون: Chen J; Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China., Li J; Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China., Wu J; Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China., Song Y; Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China., Li L; Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China., Zhang J; Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China., Dong R; Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

المصدر: Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Aug; Vol. 12 (4), pp. e1252.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 101626369 Publication Model: Print Cited Medium: Internet ISSN: 2052-1707 (Electronic) Linking ISSN: 20521707 NLM ISO Abbreviation: Pharmacol Res Perspect Subsets: MEDLINE

مواضيع طبية MeSH: Drug Interactions* , Midazolam*/pharmacokinetics , Midazolam*/administration & dosage , Midazolam*/blood , Midazolam*/analogs & derivatives , Itraconazole*/pharmacology , Itraconazole*/administration & dosage , Cytochrome P-450 CYP3A*/metabolism , Asian People* , Cytochrome P-450 CYP3A Inhibitors*/pharmacology , Cytochrome P-450 CYP3A Inhibitors*/administration & dosage, Humans ; Male ; Adult ; Young Adult ; Rifampin/pharmacology ; Rifampin/administration & dosage ; Healthy Volunteers ; Female ; Cytochrome P-450 CYP3A Inducers/pharmacology ; Area Under Curve ; Research Design ; Clinical Trials as Topic ; East Asian People

المؤلفون: Jaiprasart P; Clinical Pharmacology & Pharmacometrics, Janssen Research & Development, North Wales, PA, USA., Hellemans P; Oncology Research & Development, Janssen Research & Development, Beerse, Belgium., Jiao JJ; Statistics and Decision Science, Janssen Research & Development, Raritan, NJ, USA., Dosne AG; Clinical Pharmacology & Pharmacometrics, Janssen Research & Development, Beerse, Belgium., De Meulder M; Bioanalytical Discovery & Development Sciences, Janssen Research & Development, Beerse, Belgium., De Zwart L; Preclinical Sciences & Translational Safety, Janssen Research & Development, Beerse, Belgium., Brees L; Clinical Pharmacology Unit, Janssen Research & Development, Merksem, Belgium., Zhu W; Clinical Pharmacology & Pharmacometrics, Janssen Research & Development, Raritan, NJ, USA.

المصدر: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2024 Aug; Vol. 13 (8), pp. 852-860. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article; Clinical Trial, Phase I

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

مواضيع طبية MeSH: Drug Interactions* , Healthy Volunteers* , Carbamazepine*/pharmacology , Carbamazepine*/pharmacokinetics , Carbamazepine*/administration & dosage , Area Under Curve* , Cytochrome P-450 CYP3A*/metabolism, Humans ; Adult ; Male ; Female ; Young Adult ; Middle Aged ; Cytochrome P-450 CYP3A Inducers/pharmacology ; Cytochrome P-450 CYP2C9/metabolism ; Pyrazoles/pharmacokinetics ; Pyrazoles/adverse effects ; Pyrazoles/administration & dosage ; Pyrazoles/pharmacology ; Quinoxalines/pharmacokinetics ; Quinoxalines/adverse effects ; Quinoxalines/administration & dosage ; Quinoxalines/pharmacology ; Administration, Oral ; Receptors, Fibroblast Growth Factor/antagonists & inhibitors