المؤلفون: Guimarães Atb, Estrela Dc, de Almeida Sf, da Silva Wam, Mendes Bo, Ferreira Ro, Rabelo Lm, de Souza Jm, Malafaia G, e Silva Bc

المصدر: Journal of Obesity & Eating Disorders. 2

مصطلحات موضوعية: Gerontology, biology, Physiology, Cafeteria, Cognition, biology.organism_classification, medicine.disease, Obesity, Open access publishing, Memory improvement, Standard diet, medicine, Chronic stress, Psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::37890af2e51d96a8092fca641f4c4fcd
https://doi.org/10.21767/2471-8203.100012

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المؤلفون: Ferreira Am, Ana Rita Grosso, de Almeida Sf, João C. Sabino, Nuno C. Santos, de Almeida Mr, Claus M. Azzalin, Patrícia L. Abreu, Marco M. Domingues

المصدر: bioRxiv

مصطلحات موضوعية: Regulation of gene expression, 0303 health sciences, RNA, Biology, Embryonic stem cell, Cell biology, Chromatin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, Stem cell, Reprogramming, Gene, 030217 neurology & neurosurgery, DNA, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2375878ad4525d5d0fd72d9897ac055

المؤلفون: Gaëlle Legube, Sérgio F. de Almeida, Pablo Huertas, Alexandra C Vítor

المساهمون: Laboratoire de Biologie Cellulaire et Moléculaire du Contrôle de la Prolifération (LBCMCP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Repositório da Universidade de Lisboa, Fundação para a Ciência e a Tecnologia (Portugal), European Commission, Programa Operacional do Potencial Humano (Portugal), European Research Council, Agence Nationale de la Recherche (France), Ligue Nationale contre le Cancer (France), Institut National du Cancer (France), Universidad de Sevilla. Departamento de Genética, [Vítor,AC, de Almeida,SF] Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal. [Huertas,P] Department of Genetics, University of Seville, Seville, Spain. [Huertas,P] Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain. [Legube,G] LBCMCP, Centre de Biologie Integrative (CBI), CNRS, Université de Toulouse, Toulouse, France., Work in the SA lab was funded by PTDC/BIM-ONC/0016/2014 and PTDC/BIA-MOL/30438/2017 from Fundação para a Ciência e a Tecnologia (FCT), Portugal, by LISBOA-01-0145-FEDER-007391, project co-funded by FEDER through POR Lisboa, Portugal 2020–Programa Operacional Regional de Lisboa, and FCT, and by the IMM-Laço Fund. The GL laboratory was funded by grants from the European Research Council (ERC-2014-CoG 647344), Agence Nationale pour la Recherche (ANR-18-CE12-0015-02), the Institut National contre le Cancer (INCA), and the Ligue Nationale contre le Cancer (LNCC).

المصدر: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Frontiers Media, 2020, 7, ⟨10.3389/fmolb.2020.00024⟩
Frontiers in Molecular Biosciences, Vol 7 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla

مصطلحات موضوعية: 0301 basic medicine, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair [Medical Subject Headings], Non-homologous DNA end joining, Cell cycle checkpoint, DNA damage, DNA repair, [SDV]Life Sciences [q-bio], ComputingMilieux_LEGALASPECTSOFCOMPUTING, Review, Computational biology, Biology, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints [Medical Subject Headings], Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Cromatina, homologous recombination (HR), 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-Stranded [Medical Subject Headings], Recombinación homóloga, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Recombination, Genetic::Homologous Recombination [Medical Subject Headings], Roturas del ADN de doble cadena, Reparación del ADN por unión de extremidades, Molecular Biosciences, Molecular Biology, lcsh:QH301-705.5, ComputingMilieux_MISCELLANEOUS, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Chromosome Structures::Chromatin [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair::DNA End-Joining Repair [Medical Subject Headings], Double Strand Break Repair, Chromatin, 3. Good health, 030104 developmental biology, Daño del ADN, chemistry, lcsh:Biology (General), Homologous recombination (HR), 030220 oncology & carcinogenesis, Reparación del ADN, chromatin, Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings], DNA, non-homologous DNA end joining

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e0e0736246065f19724974f8131932
https://hal.archives-ouvertes.fr/hal-03011382

المؤلفون: Cardoso BA; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., Duque M; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., Gírio A; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., Fragoso R; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., Oliveira ML; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., Allen JR; MGH Pathology and Harvard Medical School, Charlestown MA 02129., Martins LR; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., Correia NC; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., Silveira AB; Laboratório de Biologia Molecular, Centro Infantil Boldrini, Campinas, SP., Veloso A; MGH Pathology and Harvard Medical School, Charlestown MA 02129., Kimura S; Department of Pathology, Center of Excellence for Leukemia Studies, and Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis TN., Demoen L; Department of Biomolecular Medicine, Ghent University, and Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Matthijssens F; Department of Biomolecular Medicine, Ghent University, and Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Jeha S; Department of Oncology, St. Jude Children's Research Hospital and the University of Tennessee Health Science Center, Memphis TN, US; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital and the University of Tennessee Health Science Center, Memphis TN., Cheng C; Department of Biostatistics, St. Jude Children's Research Hospital and the University of Tennessee Health Science Center, Memphis TN., Pui CH; Department of Oncology, St. Jude Children's Research Hospital and the University of Tennessee Health Science Center, Memphis TN, US; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital and the University of Tennessee Health Science Center, Memphis TN, US; Department of Pathology, St. Jude Children's Research Hospital and the University of Tennessee Health Science Center, Memphis TN., Grosso AR; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal; UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica., Neto JL; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., De Almeida SF; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon., Van Vlieberghe P; Department of Biomolecular Medicine, Ghent University, and Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Mullighan CG; Department of Pathology, Center of Excellence for Leukemia Studies, and Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis TN., Yunes JA; Laboratório de Biologia Molecular, Centro Infantil Boldrini, Campinas, SP., Langenau DM; MGH Pathology and Harvard Medical School, Charlestown MA 02129., Pflumio F; Université Paris-Saclay, INSERM, iRCM/IBFJ CEA, UMR Stabilité Génétique Cellules Souches et Radiations, F-92265, Fontenay-aux-Roses, France; OPALE Carnot Institute, The Organization for Partnerships in Leukemia, Saint-Louis Hospital, 75010 Paris., Barata JT; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon. joao_barata@medicina.ulisboa.pt.

المصدر: Haematologica [Haematologica] 2024 Jun 01; Vol. 109 (6), pp. 1713-1725. Date of Electronic Publication: 2024 Jun 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE

مواضيع طبية MeSH: Phosphatidylinositol 3-Kinases*/metabolism , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/genetics , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/pathology , Proto-Oncogene Proteins c-akt*/metabolism , Signal Transduction* , T-Cell Acute Lymphocytic Leukemia Protein 1*/metabolism , T-Cell Acute Lymphocytic Leukemia Protein 1*/genetics , TOR Serine-Threonine Kinases*/metabolism , Zebrafish*, Animals ; Humans ; Mice ; Cell Line, Tumor ; Gene Expression Regulation, Leukemic ; Receptor, Notch1/metabolism ; Receptor, Notch1/genetics ; Transcription Factors/genetics ; Transcription Factors/metabolism

المؤلفون: Faleiro I; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., Afonso AI; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., Balsinha A; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., Lucas B; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., Martin RM; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., Gomes ER; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., de Almeida SF; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.

المصدر: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Nov 27; Vol. 11, pp. 1239138. Date of Electronic Publication: 2023 Nov 27 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

المؤلفون: Martin RM; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., de Almeida MR; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., Gameiro E; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal., de Almeida SF; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.

المصدر: Nucleic acids research [Nucleic Acids Res] 2023 Nov 10; Vol. 51 (20), pp. 11010-11023.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: R-Loop Structures* , RNA*/chemistry, Humans ; DNA/metabolism ; Protein Domains ; Ribonuclease H/metabolism

المؤلفون: Chora AF; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Pedroso D; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal., Kyriakou E; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Neuherberg, Germany.; Bavarian NMR Centre, Department of Bioscience, School of Natural Sciences, Technical University of Munich, Garching, Germany., Pejanovic N; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Colaço H; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal., Gozzelino R; NOVA Medical School (NMS), Lisbon, Portugal., Barros A; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal., Willmann K; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal., Velho T; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal.; Centro Hospitalar Lisboa Norte - Hospital de Santa Maria, EPE, Avenida Professor Egas Moniz, Lisbon, Portugal., Moita CF; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal., Santos I; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal.; Serviço de Cirurgia, Centro Hospitalar de Setúbal, Setúbal, Portugal., Pereira P; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Carvalho S; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Martins FB; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Ferreira JA; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., de Almeida SF; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., Benes V; EMBL Genomics Core Facilities, Heidelberg, Germany., Anrather J; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States., Weis S; Institute for Infectious Disease and Infection Control, Friedrich-Schiller University, Jena, Germany.; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.; Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Jena, Germany., Soares MP; Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal., Geerlof A; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Neuherberg, Germany., Neefjes J; Department of Cell and Chemical Biology, LUMC, Leiden, Netherlands., Sattler M; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Neuherberg, Germany.; Bavarian NMR Centre, Department of Bioscience, School of Natural Sciences, Technical University of Munich, Garching, Germany., Messias AC; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Neuherberg, Germany.; Bavarian NMR Centre, Department of Bioscience, School of Natural Sciences, Technical University of Munich, Garching, Germany., Neves-Costa A; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal., Moita LF; Innate Immunity and Inflammation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal.; Instituto de Histologia e Biologia do Desenvolvimento, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal.

المصدر: ELife [Elife] 2022 Dec 07; Vol. 11. Date of Electronic Publication: 2022 Dec 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Anthracyclines*/pharmacology , NF-kappa B*, Animals ; Mice ; Antibiotics, Antineoplastic/pharmacology ; Doxorubicin/pharmacology ; DNA Damage ; DNA

المؤلفون: Sabino JC; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., de Almeida MR; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Abreu PL; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Ferreira AM; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Caldas P; Associate laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade Nova de Lisboa, Caparica, Portugal.; UCIBIO-REQUIMTE, Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade Nova de Lisboa, Lisbon, Portugal., Domingues MM; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Santos NC; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Azzalin CM; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Grosso AR; Associate laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade Nova de Lisboa, Caparica, Portugal.; UCIBIO-REQUIMTE, Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade Nova de Lisboa, Lisbon, Portugal., de Almeida SF; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.

المصدر: ELife [Elife] 2022 Feb 22; Vol. 11. Date of Electronic Publication: 2022 Feb 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Dioxygenases*/genetics , R-Loop Structures*, 5-Methylcytosine/metabolism ; Animals ; Cytosine ; DNA/metabolism ; DNA Methylation ; Epigenesis, Genetic ; Epigenomics ; Humans ; Mice

المؤلفون: Gomes ER; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. Electronic address: edgargomes@medicina.ulisboa.pt., de Almeida SF; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. Electronic address: sergioalmeida@medicina.ulisboa.pt.

المصدر: Developmental cell [Dev Cell] 2021 Nov 22; Vol. 56 (22), pp. 3040-3041.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

مواضيع طبية MeSH: Cell Nucleus* , DNA Damage*/genetics, Nuclear Envelope ; Phosphoproteins/genetics