المؤلفون: Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Pharmacy Leiden, Leiden, The Netherlands., de Jong LM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands., van der Geest R; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands., de Leeuw LR; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands., Krisnamurthi R; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands., Geerling JJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands., Van Eck M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Pharmacy Leiden, Leiden, The Netherlands.

المصدر: Biomolecules [Biomolecules] 2024 Apr 02; Vol. 14 (4). Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Apolipoproteins E*/deficiency , Apolipoproteins E*/genetics , Atherosclerosis*/drug therapy , Atherosclerosis*/metabolism , Atherosclerosis*/prevention & control , Atherosclerosis*/pathology , Benzenesulfonamides* , Fluorocarbons* , Macrophages*/metabolism , Macrophages*/drug effects, Animals ; Male ; Mice ; ATP Binding Cassette Transporter 1/metabolism ; ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 1/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 1/genetics ; Liver/metabolism ; Liver/drug effects ; Liver/pathology ; Liver X Receptors/agonists ; Liver X Receptors/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Triglycerides/blood ; Triglycerides/metabolism

المؤلفون: Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333CC Leiden, the Netherlands.. Electronic address: hoekstra@lacdr.leidenuniv.nl., Nahon JE; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333CC Leiden, the Netherlands., de Jong LM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333CC Leiden, the Netherlands., Kröner MJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333CC Leiden, the Netherlands., de Leeuw LR; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333CC Leiden, the Netherlands., Van Eck M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333CC Leiden, the Netherlands.

المصدر: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2019 Jun 01; Vol. 1865 (6), pp. 1402-1409. Date of Electronic Publication: 2019 Feb 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE

مواضيع طبية MeSH: Apolipoproteins E/*genetics , Atherosclerosis/*genetics , Enzyme Inhibitors/*pharmacology , Fatty Liver/*prevention & control , Isoquinolines/*pharmacology , Protein-Arginine N-Methyltransferases/*genetics, Adipose Tissue, White/drug effects ; Adipose Tissue, White/enzymology ; Adipose Tissue, White/pathology ; Allosteric Regulation/drug effects ; Animals ; Aorta/drug effects ; Aorta/metabolism ; Aorta/pathology ; Apolipoproteins E/deficiency ; Atherosclerosis/enzymology ; Atherosclerosis/etiology ; Atherosclerosis/pathology ; Cholesterol/metabolism ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Disease Susceptibility ; Fatty Liver/etiology ; Fatty Liver/genetics ; Fatty Liver/pathology ; Foam Cells/drug effects ; Foam Cells/metabolism ; Foam Cells/pathology ; Gene Expression Regulation ; Liver/drug effects ; Liver/enzymology ; Liver/pathology ; Liver X Receptors/genetics ; Liver X Receptors/metabolism ; Male ; Mice ; Mice, Knockout, ApoE ; Protein-Arginine N-Methyltransferases/antagonists & inhibitors ; Protein-Arginine N-Methyltransferases/metabolism ; Signal Transduction ; Triglycerides/metabolism

المؤلفون: Korte-Bouws GAH; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Faculty of Science, Universities 99, 3584 CG Utrecht, The Netherlands. G.A.H.Korte@uu.nl., Albers E; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Faculty of Science, Universities 99, 3584 CG Utrecht, The Netherlands. e.g.albers@students.uu.nl., Voskamp M; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Faculty of Science, Universities 99, 3584 CG Utrecht, The Netherlands. m.j.voskamp@students.uu.nl., Hendriksen H; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Faculty of Science, Universities 99, 3584 CG Utrecht, The Netherlands. H.Hendriksen@uu.nl., de Leeuw LR; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Faculty of Science, Universities 99, 3584 CG Utrecht, The Netherlands. l.r.deleeuw@uu.nl., Güntürkün O; Department of Biopsychology, Faculty of Psychology, Ruhr-Universität Bochum, Universitätsstraße 150, D-44780 Bochum, Germany. onur.guentuerkuen@ruhr-uni-bochum.de., de Roock S; Paediatric Rheumatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584 EA Utrecht, The Netherlands. S.deRoock@umcutrecht.nl., Vastert SJ; Paediatric Rheumatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584 EA Utrecht, The Netherlands. B.Vastert@umcutrecht.nl., Korte SM; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Faculty of Science, Universities 99, 3584 CG Utrecht, The Netherlands. Sijmen.Korte@rub.de.; Department of Biopsychology, Faculty of Psychology, Ruhr-Universität Bochum, Universitätsstraße 150, D-44780 Bochum, Germany. Sijmen.Korte@rub.de.

المصدر: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2019 Jan 08; Vol. 12 (1). Date of Electronic Publication: 2019 Jan 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238453 Publication Model: Electronic Cited Medium: Print ISSN: 1424-8247 (Print) Linking ISSN: 14248247 NLM ISO Abbreviation: Pharmaceuticals (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Louwe MC; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Lammers B; Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands., Frias MA; Department of Internal Medicine, Endocrinology, Diabetology and Nutrition, University of Geneva, Geneva, Switzerland., Foks AC; Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands., de Leeuw LR; Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands., Hildebrand RB; Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands., Kuiper J; Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands., Smit JWA; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands., Van Berkel TJC; Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands., James RW; Department of Internal Medicine, Endocrinology, Diabetology and Nutrition, University of Geneva, Geneva, Switzerland., Geerling JJ; Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands., Rensen PCN; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Van Eck M; Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands. Electronic address: m.eck@lacdr.leidenuniv.nl.

المصدر: Atherosclerosis [Atherosclerosis] 2016 Aug; Vol. 251, pp. 159-163. Date of Electronic Publication: 2016 Jun 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE

مواضيع طبية MeSH: ATP Binding Cassette Transporter 1/*deficiency , Heart/*physiopathology , Myocardial Infarction/*genetics , Myocardial Infarction/*prevention & control, Animals ; Atherosclerosis/metabolism ; B-Lymphocytes/cytology ; Bone Marrow Transplantation ; Female ; Leukocytes/cytology ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myocardial Infarction/metabolism