المؤلفون: Dos Santos DF; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Regional Blood Center of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil. Electronic address: daiane-santos@alumni.usp.br., de Pilger DRB; Federal University of São Paulo, São Paulo, São Paulo, Brazil; Department of Microbiology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil., Vandermeulen C; Protein Signaling and Interactions (GIGA), University of Liège, Liège, Belgium., Khouri R; Gonçalo Moniz Research Center (CPqGM), Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Bahia, Brazil., Mantoani SP; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Nunes PSG; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., de Andrade P; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Carvalho I; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Casseb J; Institute of Tropical Medicine of São Paulo, University of São Paulo, São Paulo, São Paulo, Brazil., Twizere JC; Protein Signaling and Interactions (GIGA), University of Liège, Liège, Belgium., Willems L; Molecular and Cellular Epigenetics (GIGA), University of Liège, Liège, Belgium., Freitas-Junior L; Department of Microbiology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil., Kashima S; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Regional Blood Center of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Nov 15; Vol. 28 (22), pp. 115746. Date of Electronic Publication: 2020 Sep 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Gene Products, tax/*antagonists & inhibitors , Heterocyclic Compounds/*pharmacology , Human T-lymphotropic virus 1/*drug effects , Triazoles/*pharmacology, Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Cell Cycle Checkpoints/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Gene Products, tax/metabolism ; Heterocyclic Compounds/chemistry ; Humans ; Molecular Structure ; Structure-Activity Relationship ; Triazoles/chemistry

المؤلفون: Santana CJC; Laboratory of Toxinology, Department of Physiological Sciences, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil.; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Magalhães ACM; Laboratory of Toxinology, Department of Physiological Sciences, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Prías-Márquez CA; Laboratory of Toxinology, Department of Physiological Sciences, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil.; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Falico DA; Laboratory of Toxinology, Department of Physiological Sciences, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil.; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Dos Santos Júnior ACM; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil.; Laboratory of Gene Biology, Department of Cell Biology, University of Brasília, Brasília 70.910-900, Brazil., Lima BD; Laboratory of Gene Biology, Department of Cell Biology, University of Brasília, Brasília 70.910-900, Brazil., Ricart CAO; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., de Pilger DRB; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05.508-900, Brazil., Bonotto RM; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05.508-900, Brazil., Moraes CB; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05.508-900, Brazil., Freitas-Júnior LH; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05.508-900, Brazil., Álvares ADCM; Laboratory of Biophysics, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Freitas SM; Laboratory of Biophysics, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Luz IS; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Pires OR Jr; Laboratory of Toxinology, Department of Physiological Sciences, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Fontes W; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil., Castro MS; Laboratory of Toxinology, Department of Physiological Sciences, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil.; Laboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biology, University of Brasília, Brasília 70.910-900, Brazil.

المصدر: Biomolecules [Biomolecules] 2020 May 20; Vol. 10 (5). Date of Electronic Publication: 2020 May 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Amphibian Proteins/*metabolism , Anura/*metabolism , Defensins/*metabolism , Skin/*metabolism, Amphibian Proteins/chemistry ; Amphibian Proteins/pharmacology ; Animals ; Arboviruses/drug effects ; Bacteria/drug effects ; Candida/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cells, Cultured ; Defensins/chemistry ; Defensins/pharmacology ; Hemolysis/drug effects ; Humans ; Neutrophils/drug effects ; Protein Conformation, alpha-Helical ; Trypanosoma cruzi/drug effects