المؤلفون: Ville A Palomäki, Vesa Koivukangas, Sanna Meriläinen, Petri Lehenkari, Tuomo J Karttunen

المصدر: Adipocyte, Vol 11, Iss 1, Pp 99-107 (2022)

مصطلحات موضوعية: adipocyte size, fat cell size, qupath, adipocyte tools, imagej, obesity, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Cytology, QH573-671, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2162-3945; https://doaj.org/toc/2162-397X

URL الوصول: https://doaj.org/article/9ff3efc749c24ab88d332bb6629a12b5

المؤلفون: Helen M. M. Waddell, Matthew K. Moore, Morgan A. Herbert-Olsen, Martin K. Stiles, Rexson D. Tse, Sean Coffey, Regis R. Lamberts, Hamish M. Aitken-Buck

المصدر: Adipocyte, Vol 11, Iss 1, Pp 325-334 (2022)

مصطلحات موضوعية: Epicardial adipose tissue, sex differences, fat cell size, paracardial adipose tissue, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Cytology, QH573-671, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2162-3945; https://doaj.org/toc/2162-397X

URL الوصول: https://doaj.org/article/8e22d605723a49a89193f7437e2bc3dd

المؤلفون: Ishwarlal Jialal, Beverley Adams-Huet, Sridevi Devaraj

المصدر: Journal of Clinical Medicine, Vol 12, Iss 13, p 4247 (2023)

مصطلحات موضوعية: fat cell size, gluteal fat, inflammation, fibrosis, angiogenesis, metabolic syndrome, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2077-0383/12/13/4247; https://doaj.org/toc/2077-0383

URL الوصول: https://doaj.org/article/5d4d7909cf414c639c81c437dc4ff7c6

المؤلفون: Meyer, Lauren K, Ciaraldi, Theodore P, Henry, Robert R, Wittgrove, Alan C, Phillips, Susan A

المصدر: Adipocyte. 2(4)

مصطلحات موضوعية: Nutrition, HIV/AIDS, Clinical Research, Obesity, Metabolic and endocrine, adipocyte, fat cell size, adiponectin, high molecular weight, insulin resistance, adipose tissue depots, subcutaneous adipose tissue, visceral adipose tissue

URL الوصول: https://escholarship.org/uc/item/53d3c851

المؤلفون: Devaraj, Ishwarlal Jialal, Beverley Adams-Huet, Sridevi

المصدر: Journal of Clinical Medicine; Volume 12; Issue 13; Pages: 4247

مصطلحات موضوعية: fat cell size, gluteal fat, inflammation, fibrosis, angiogenesis, metabolic syndrome

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=multidiscipl::cc4ddf5b0aeec317fa5dd528a93d708d

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المؤلفون: Jocken, Johan W E, Langin, Dominique, Smit, Egbert, Saris, Wim Hm, Valle, Carine, Hul, Gabby B, Holm, Cecilia, Arner, Peter, Blaak, Ellen E

المصدر: Journal of Clinical Endocrinology and Metabolism. 92(6):2292-2299

مصطلحات موضوعية: independent of fat mass. Data on weight reduction indicated that also other factors (e.g. leptin) relate to ATGL and HSL protein expression., we investigated whether a possible impaired expression could be reversed by a period of weight reduction. METHODS: Adipose tissue biopsies were taken from obese subjects (n = 44) with a wide range of insulin resistance, Obesity is associated with increased triacylglycerol (TAG) storage in adipose tissue and insulin resistance. The mobilization of stored TAG is mediated by hormone-sensitive lipase (HSL) and the recently discovered adipose triglyceride lipase (ATGL). The aim of the present study was to examine whether ATGL and HSL mRNA and protein expression are altered in insulin-resistant conditions. In addition, before and just after a 10-wk hypocaloric diet. ATGL and HSL protein and mRNA expression was determined by Western blot and quantitative RT-PCR, independent of age, gender, fat cell size, respectively. RESULTS: Fasting insulin levels and the degree of insulin resistance (using the homeostasis model assessment index for insulin resistance) were negatively correlated with ATGL and HSL protein expression, ATGL and HSL mRNA and protein levels seem to be highly correlated, and body composition. Both mRNA and protein levels of ATGL and HSL were reduced in insulin-resistant compared with insulin-sensitive subjects (P < 0.05). Weight reduction significantly decreased ATGL and HSL mRNA and protein expression. A positive correlation between the decrease in leptin and the decrease in ATGL protein level after weight reduction was observed. Finally, indicating a tight coregulation and transcriptional control. CONCLUSIONS: In obese subjects, insulin resistance and hyperinsulinemia are strongly associated with ATGL and HSL mRNA and protein expression, Medicin och hälsovetenskap, Klinisk medicin, Endokrinologi och diabetes, Medical and Health Sciences, Clinical Medicine, Endocrinology and Diabetes

URL الوصول: https://lup.lub.lu.se/record/166621
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17356053&dopt=Abstract
http://dx.doi.org/10.1210/jc.2006-1318

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المؤلفون: K.A. Varady, D.J. Roohk, Y.C. Loe, B.K. McEvoy-Hein, M.K. Hellerstein

المصدر: Journal of Lipid Research, Vol 48, Iss 10, Pp 2212-2219 (2007)

مصطلحات موضوعية: calorie restriction, adipose tissue, fat cell size, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520424654; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/51118c3a5ea64063a76639b83605db24

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