المؤلفون: Kunjiappan S; Department of Biotechnology, Kalasalingam Academy of Research and Education, Krishnankoil 626126, Tamilnadu, India. Electronic address: selvaraj.k@kl.ac.in., Panneerselvam T; Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy, Elayampalayam, Namakkal 637205, Tamilnadu, India., Pavadai P; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, M.S. Ramaiah University of Applied Sciences, Bengaluru 560054, Karnataka, India., Balakrishnan V; Department of Biotechnology, Kalasalingam Academy of Research and Education, Krishnankoil 626126, Tamilnadu, India., Pandian SRK; Department of Biotechnology, Kalasalingam Academy of Research and Education, Krishnankoil 626126, Tamilnadu, India., Palanisamy P; School of Mechanical Engineering, Vellore Institute of Technology, Vellore 632014, Tamilnadu, India., Sankaranarayanan M; Medicinal Chemistry Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science-Pilani, Pilani Campus, Pilani-333031, Rajasthan, India., Kabilan SJ; Department of Biotechnology, Kalasalingam Academy of Research and Education, Krishnankoil 626126, Tamilnadu, India., Sundaram GA; Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Poonamallee High Road, Chennai 600 077, Tamilnadu, India., Tseng WL; Department of Chemistry, National Sun Yat-sen University, No. 70, Lien-hai Road, Gushan District, Kaohsiung city 80424, Taiwan; School of Pharmacy, Kaohsiung Medical University, No. 100, Shiquan 1st Road, Sanmin District, Kaohsiung city 80708, Taiwan., Kumar ASK; Department of Chemistry, National Sun Yat-sen University, No. 70, Lien-hai Road, Gushan District, Kaohsiung city 80424, Taiwan. Electronic address: krishnakumar@mail.nsysu.edu.tw.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 277 (Pt 3), pp. 134406. Date of Electronic Publication: 2024 Aug 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Folic Acid*/chemistry , Folic Acid*/pharmacology , Nanoparticles*/chemistry , beta-Glucans*/chemistry , beta-Glucans*/pharmacology , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Folate Receptors, GPI-Anchored*/metabolism, Humans ; MCF-7 Cells ; Female ; Polyethylene Glycols/chemistry ; Pyrimidines/chemistry ; Pyrimidines/pharmacology ; Drug Carriers/chemistry ; Drug Liberation ; Apoptosis/drug effects ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry

المؤلفون: Wang Y; Department of Pharmacy, Affiliated Zhongshan Hospital of Dalian University, Dalian, People's Republic of China., Guo R; School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, People's Republic of China., Zou M; Department of Pharmacy, Affiliated Zhongshan Hospital of Dalian University, Dalian, People's Republic of China., Jiang L; Department of Pharmacy, Affiliated Zhongshan Hospital of Dalian University, Dalian, People's Republic of China., Kong L; School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, People's Republic of China., Zhao S; Department of Pharmacy, Affiliated Zhongshan Hospital of Dalian University, Dalian, People's Republic of China., Zhang X; Department of Pharmacy, Affiliated Zhongshan Hospital of Dalian University, Dalian, People's Republic of China., Wang W; Department of Pharmacy, Affiliated Zhongshan Hospital of Dalian University, Dalian, People's Republic of China., Xu B; Department of Pharmacy, Affiliated Zhongshan Hospital of Dalian University, Dalian, People's Republic of China.

المصدر: International journal of nanomedicine [Int J Nanomedicine] 2024 May 13; Vol. 19, pp. 4217-4234. Date of Electronic Publication: 2024 May 13 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE

مواضيع طبية MeSH: Arthritis, Rheumatoid*/drug therapy , Curcumin*/administration & dosage , Curcumin*/chemistry , Curcumin*/pharmacology , Folate Receptors, GPI-Anchored*/metabolism , Micelles* , Reactive Oxygen Species*/metabolism, Animals ; Male ; Mice ; Rats ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/pharmacokinetics ; Arthritis, Experimental/drug therapy ; Disease Models, Animal ; Drug Carriers/chemistry ; Folic Acid/chemistry ; Folic Acid/pharmacology ; Macrophages/drug effects ; Macrophages/metabolism ; Particle Size ; Polyethylene Glycols/chemistry ; RAW 264.7 Cells

المؤلفون: Elshami FI; Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt., Elrefaei G; Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt., Ibrahim MM; Department of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia., Elmehasseb I; Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt., Shaban SY; Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt. Electronic address: shaban.shaban@sci.kfs.edu.eg.

المصدر: Carbohydrate research [Carbohydr Res] 2024 Sep; Vol. 543, pp. 109207. Date of Electronic Publication: 2024 Jul 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0043535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-426X (Electronic) Linking ISSN: 00086215 NLM ISO Abbreviation: Carbohydr Res Subsets: MEDLINE

مواضيع طبية MeSH: Chitosan*/chemistry , Chitosan*/pharmacology , Folic Acid*/chemistry , Nanoparticles*/chemistry , Pyridines*/chemistry , Pyridines*/pharmacology , Glutathione*/chemistry , Glutathione*/metabolism, Humans ; MCF-7 Cells ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Drug Carriers/chemistry ; Cell Survival/drug effects ; Folate Receptors, GPI-Anchored/metabolism ; Drug Delivery Systems ; Serum Albumin, Human/chemistry ; Serum Albumin, Human/metabolism ; Drug Liberation ; Cell Proliferation/drug effects ; Particle Size

المؤلفون: Li Z; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Lan J; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Liu L; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Wang Y; Shanghai Children's Medical Center, Shanghai 200127, China., Chen L; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Zeng R; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Gu D; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Hu R; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Zhang T; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: zhangtongshutcm@hotmail.com., Ding Y; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; National Innovation Platform for medical industry-education integration, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: Dingyue-2001@hotmail.com.

المصدر: International journal of pharmaceutics [Int J Pharm] 2024 Oct 25; Vol. 664, pp. 124583. Date of Electronic Publication: 2024 Aug 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Liposomes* , Breast Neoplasms*/pathology , Breast Neoplasms*/drug therapy , Indocyanine Green*/administration & dosage , Berberine*/administration & dosage , Berberine*/pharmacology, Female ; Animals ; Mice ; Humans ; Mice, Inbred BALB C ; Cell Line, Tumor ; Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/pharmacology ; Photothermal Therapy/methods ; HSP70 Heat-Shock Proteins/metabolism ; HSP90 Heat-Shock Proteins/metabolism ; Heat-Shock Proteins/metabolism ; Inflammation/drug therapy ; Neoplasm Metastasis/prevention & control ; Folate Receptors, GPI-Anchored/metabolism

المؤلفون: Einafshar E; Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Javid H; Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Medical Laboratory Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran., Amiri H; Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Akbari-Zadeh H; Department of Medical Physics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Hashemy SI; Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: hashemyi@mums.ac.ir.

المصدر: Carbohydrate polymers [Carbohydr Polym] 2024 Sep 15; Vol. 340, pp. 122328. Date of Electronic Publication: 2024 May 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1344 (Electronic) Linking ISSN: 01448617 NLM ISO Abbreviation: Carbohydr Polym Subsets: MEDLINE

مواضيع طبية MeSH: Curcumin*/chemistry , Curcumin*/pharmacology , Graphite*/chemistry , Graphite*/pharmacology , Prostatic Neoplasms*/drug therapy , Prostatic Neoplasms*/diagnostic imaging , Prostatic Neoplasms*/pathology , beta-Cyclodextrins*/chemistry , Theranostic Nanomedicine*/methods , Folic Acid*/chemistry , Folic Acid*/pharmacology , Cell Proliferation*/drug effects, Male ; Humans ; Apoptosis/drug effects ; Cell Line, Tumor ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Drug Carriers/chemistry ; Magnetic Resonance Imaging/methods ; Nanoparticles/chemistry ; Folate Receptors, GPI-Anchored/metabolism ; Drug Liberation ; Magnetite Nanoparticles/chemistry

المؤلفون: Ok HW; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea., Jin S; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea., Park G; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea., Jana B; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.; Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur 741246, India., Ryu JH; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.

المصدر: Molecular pharmaceutics [Mol Pharm] 2024 Sep 02; Vol. 21 (9), pp. 4498-4509. Date of Electronic Publication: 2024 Jul 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Folic Acid*/chemistry , beta-Cyclodextrins*/chemistry , Drug Delivery Systems*/methods , Peptides*/chemistry , Peptides*/pharmacology , Xenograft Model Antitumor Assays*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Organelles/drug effects ; Organelles/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/administration & dosage ; Mice, Nude ; Neoplasms/drug therapy ; Neoplasms/pathology ; Neoplasms/metabolism ; Folate Receptors, GPI-Anchored/metabolism ; Prodrugs/chemistry ; Prodrugs/pharmacology ; Prodrugs/administration & dosage ; Mitochondria/drug effects ; Mitochondria/metabolism ; Female

المؤلفون: McMullon GT; Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom., Ezdoglian A; Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Location VU University Medical Center, 1081 HV Amsterdam, Netherlands., Booth AC; Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom., Jimenez-Royo P; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom., Murphy PS; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom., Jansen G; Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Location VU University Medical Center, 1081 HV Amsterdam, Netherlands., van der Laken CJ; Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Location VU University Medical Center, 1081 HV Amsterdam, Netherlands., Faulkner S; Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Aug 22; Vol. 67 (16), pp. 14062-14076. Date of Electronic Publication: 2024 Aug 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Folic Acid*/chemistry , Folic Acid*/metabolism , Terbium*/chemistry, Humans ; Coordination Complexes/chemistry ; Coordination Complexes/chemical synthesis ; Coordination Complexes/metabolism ; Folate Receptors, GPI-Anchored/metabolism ; Luminescent Agents/chemistry ; Luminescent Agents/chemical synthesis ; Carboxylic Acids/chemical synthesis ; Carboxylic Acids/chemistry

المؤلفون: Liang H; GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, PET Center and Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China., Chen Z; GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, PET Center and Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China., Mo C; GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, PET Center and Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China., Tang G; GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, PET Center and Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China.

المصدر: Journal of labelled compounds & radiopharmaceuticals [J Labelled Comp Radiopharm] 2024 Aug; Vol. 67 (10), pp. 334-340. Date of Electronic Publication: 2024 Jul 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7610510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1344 (Electronic) Linking ISSN: 03624803 NLM ISO Abbreviation: J Labelled Comp Radiopharm Subsets: MEDLINE

مواضيع طبية MeSH: Positron-Emission Tomography*/methods , Fluorine Radioisotopes*/chemistry , Folic Acid*/chemistry , Folic Acid*/pharmacokinetics, Animals ; Mice ; Humans ; Tissue Distribution ; KB Cells ; Radiopharmaceuticals/chemical synthesis ; Radiopharmaceuticals/pharmacokinetics ; Radiopharmaceuticals/chemistry ; Chemistry Techniques, Synthetic ; Folate Receptors, GPI-Anchored/metabolism ; Heterocyclic Compounds, 1-Ring

المؤلفون: Xu ZL; Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou 510080, China., Lyu KX; Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou 510080, China., Fang RH; Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou 510080, China., Huang BX; Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou 510080, China., Zhang MJ; Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou 510080, China., Chen LF; Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou 510080, China., Chen Y; Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou 510080, China., Lei WB; Department of Otorhinolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute, Sun Yat-sen University, Guangzhou 510080, China.

المصدر: Zhonghua yi xue za zhi [Zhonghua Yi Xue Za Zhi] 2024 Jul 09; Vol. 104 (26), pp. 2445-2448.

نوع المنشور: English Abstract; Journal Article

بيانات الدورية: Publisher: Zhonghua yi xue hui Country of Publication: China NLM ID: 7511141 Publication Model: Print Cited Medium: Print ISSN: 0376-2491 (Print) Linking ISSN: 03762491 NLM ISO Abbreviation: Zhonghua Yi Xue Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Squamous Cell Carcinoma of Head and Neck*/diagnosis , Squamous Cell Carcinoma of Head and Neck*/blood , Neoplastic Cells, Circulating*/metabolism , Head and Neck Neoplasms*/diagnosis , Head and Neck Neoplasms*/blood, Humans ; Female ; Male ; Middle Aged ; Aged ; Sensitivity and Specificity ; Biomarkers, Tumor/blood ; ROC Curve ; Folate Receptors, GPI-Anchored/metabolism ; Folate Receptors, GPI-Anchored/blood

المؤلفون: Lodhi MS; School of Biochemistry and Biotechnology, University of the Punjab, Lahore 54890, Pakistan.; Institute of molecular Biology and Biotechnology, The University of Lahore, Lahore 58810, Pakistan., Khalid F; School of Biochemistry and Biotechnology, University of the Punjab, Lahore 54890, Pakistan., Khan MT; Institute of molecular Biology and Biotechnology, The University of Lahore, Lahore 58810, Pakistan., Samra ZQ; School of Biochemistry and Biotechnology, University of the Punjab, Lahore 54890, Pakistan., Muhammad S; Department of Physics, College of Science, King Khalid University, Abha 61413, Saudi Arabia., Zhang YJ; College of Life Sciences, Chongqing Normal University, Shapingba, Chongqing 401331, China., Mou K; Department of Neurosurgery, Bishan Hospital of Chongqing, Chongqing 402760, China.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2022 Jan 01; Vol. 27 (1). Date of Electronic Publication: 2022 Jan 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies*/chemistry , Antibodies*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Drug Delivery Systems* , Magnetite Nanoparticles*/chemistry , Magnetite Nanoparticles*/therapeutic use , Methotrexate*/chemistry , Methotrexate*/pharmacology , Nanocomposites*/chemistry , Nanocomposites*/therapeutic use, Folate Receptors, GPI-Anchored/*antagonists & inhibitors, Animals ; Folate Receptors, GPI-Anchored/immunology ; HeLa Cells ; Humans ; Rabbits