المؤلفون: Jäger N; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, 37073 Göttingen, Germany., Ayyub SA; Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany., Peske F; Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany., Liedtke D; Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany., Bohne J; Institute of Virology, Hannover Medical School, 30625 Hannover, Germany., Hoffmann M; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, 37073 Göttingen, Germany., Rodnina MV; Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany., Pöhlmann S; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, 37073 Göttingen, Germany.

المصدر: Viruses [Viruses] 2024 Apr 10; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Fusion Proteins, gag-pol*/genetics , Fusion Proteins, gag-pol*/metabolism , HIV Infections*/virology , HIV Infections*/genetics , HIV Infections*/metabolism , HIV-1*/genetics , HIV-1*/physiology , RNA-Binding Proteins*/metabolism, Humans ; Frameshifting, Ribosomal ; Gene Expression Regulation, Viral ; HEK293 Cells ; Leukemia Virus, Murine/genetics ; Leukemia Virus, Murine/physiology ; Virus Replication

المؤلفون: Centazzo M; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', 20122 Milan, Italy., Manganaro L; INGM, Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', 20122 Milan, Italy.; Department of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy., Alvisi G; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.

المصدر: Viruses [Viruses] 2023 Mar 09; Vol. 15 (3). Date of Electronic Publication: 2023 Mar 09.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: HIV Protease*/genetics , HIV Protease*/metabolism , Fusion Proteins, gag-pol*/metabolism, Humans ; Proteolysis ; Endopeptidases/metabolism ; Virion/metabolism ; Antiviral Agents

المؤلفون: Horikawa M; Department of Molecular Biology, Faculty of Mecidine and Graduate School of Medicine, Hokkaido University, Sapporo, 060-8638, Japan., Sabe H; Department of Molecular Biology, Faculty of Mecidine and Graduate School of Medicine, Hokkaido University, Sapporo, 060-8638, Japan., Onodera Y; Department of Molecular Biology, Faculty of Mecidine and Graduate School of Medicine, Hokkaido University, Sapporo, 060-8638, Japan; Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan. Electronic address: yonodera@med.hokudai.ac.jp.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Dec 10; Vol. 582, pp. 93-99. Date of Electronic Publication: 2021 Oct 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Selection, Genetic*, Acetyltransferases/*genetics , Cell Engineering/*methods , Fusion Proteins, gag-pol/*genetics , Inteins/*genetics , Membrane Glycoproteins/*genetics , Viral Envelope Proteins/*genetics, Acetyltransferases/metabolism ; Artificial Virus-Like Particles/chemistry ; Artificial Virus-Like Particles/metabolism ; Cell Line, Tumor ; Epithelial Cells/cytology ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Fusion Proteins, gag-pol/metabolism ; Gene Expression ; Genes, Reporter ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Humans ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Membrane Glycoproteins/metabolism ; Plasmids/chemistry ; Plasmids/metabolism ; Puromycin/pharmacology ; Transfection/methods ; Vesicular stomatitis Indiana virus/genetics ; Vesicular stomatitis Indiana virus/metabolism ; Viral Envelope Proteins/metabolism ; Red Fluorescent Protein

المؤلفون: Lin YR; Institute of Clinical Medicine, National Yang Ming Chiao Tung University School of Medicine, 112, Taipei, Taiwan., Chu SM; Institute of Clinical Medicine, National Yang Ming Chiao Tung University School of Medicine, 112, Taipei, Taiwan., Yu FH; Institute of Clinical Medicine, National Yang Ming Chiao Tung University School of Medicine, 112, Taipei, Taiwan., Huang KJ; Division of Clinical Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan., Wang CT; Institute of Clinical Medicine, National Yang Ming Chiao Tung University School of Medicine, 112, Taipei, Taiwan. chintien@nycu.edu.tw.; Division of Clinical Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan. chintien@nycu.edu.tw.

المصدر: BMC microbiology [BMC Microbiol] 2022 Apr 09; Vol. 22 (1), pp. 94. Date of Electronic Publication: 2022 Apr 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100966981 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2180 (Electronic) Linking ISSN: 14712180 NLM ISO Abbreviation: BMC Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: HIV-1*/genetics, Fusion Proteins, gag-pol/genetics ; Fusion Proteins, gag-pol/metabolism ; Leucine Zippers/genetics ; Virion ; Virus Assembly

المؤلفون: Nili M; Department of Virology, Tarbiat Modares University, Tehran, Iran., Tayeri K; Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran., Gholami M; Department of Virology, Tarbiat Modares University, Tehran, Iran., Moallemi S; Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran., Sabahi F; Department of Virology, Tarbiat Modares University, Tehran, Iran., Kalhori S; Qazvin University of Medical Sciences, Qazvin, Iran., Baesi K; Hepatitis and AIDS Department, Pasteur Institute of Iran, Tehran, Iran., Hasibi M; Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.

المصدر: Infectious disorders drug targets [Infect Disord Drug Targets] 2019; Vol. 19 (1), pp. 67-72.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101269158 Publication Model: Print Cited Medium: Internet ISSN: 2212-3989 (Electronic) Linking ISSN: 18715265 NLM ISO Abbreviation: Infect Disord Drug Targets Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents/*pharmacology , Fusion Proteins, gag-pol/*genetics , Genome, Viral/*genetics , HIV Infections/*drug therapy , HIV-1/*genetics, Anti-HIV Agents/therapeutic use ; Drug Resistance, Viral/genetics ; Female ; Fusion Proteins, gag-pol/isolation & purification ; HIV Infections/blood ; HIV Infections/virology ; HIV-1/drug effects ; HIV-1/isolation & purification ; Humans ; Iran ; Male ; Mutation ; Phylogeny ; Reference Standards ; Sequence Analysis, RNA/standards ; Treatment Outcome

المؤلفون: Kim JG; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Shan L; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA.

المصدر: Viruses [Viruses] 2022 May 28; Vol. 14 (6). Date of Electronic Publication: 2022 May 28.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: HIV Protease*/metabolism , HIV-1*/physiology, CARD Signaling Adaptor Proteins/metabolism ; Fusion Proteins, gag-pol/metabolism ; Humans ; Neoplasm Proteins/metabolism ; Reverse Transcriptase Inhibitors/pharmacology

المؤلفون: Sauermann U; Unit of Infection Models, Deutsches Primatenzentrum GmbH, Goettingen, Germany., Radaelli A; Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy., Stolte-Leeb N; Unit of Infection Models, Deutsches Primatenzentrum GmbH, Goettingen, Germany., Raue K; Unit of Infection Models, Deutsches Primatenzentrum GmbH, Goettingen, Germany., Bissa M; Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy., Zanotto C; Department of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy., Krawczak M; Institute of Medical Informatics and Statistics, Christian-Albrechts University, Kiel, Germany., Tenbusch M; Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany., Überla K; University Hospital Erlangen, Institute of Clinical and Molecular Virology, Erlangen, Germany., Keele BF; AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., De Giuli Morghen C; Department of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy.; Catholic University Our Lady of Good Counsel, Tirana, Albania., Sopper S; Clinic for Hematology and Oncology, Medical University Innsbruck, Tyrolean Cancer Research Center, Innsbruck, Austria., Stahl-Hennig C; Unit of Infection Models, Deutsches Primatenzentrum GmbH, Goettingen, Germany stahlh@dpz.eu.

المصدر: Journal of virology [J Virol] 2017 Nov 14; Vol. 91 (23). Date of Electronic Publication: 2017 Nov 14 (Print Publication: 2017).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

مواضيع طبية MeSH: Fusion Proteins, gag-pol/*genetics , Gene Products, env/*genetics , SAIDS Vaccines/*immunology , Simian Acquired Immunodeficiency Syndrome/*prevention & control , Simian Immunodeficiency Virus/*immunology, Adenoviridae/genetics ; Animals ; CD4-Positive T-Lymphocytes/metabolism ; CD4-Positive T-Lymphocytes/virology ; CD8-Positive T-Lymphocytes/metabolism ; Chemokine CXCL10/blood ; Fowlpox virus ; Fusion Proteins, gag-pol/immunology ; Gene Products, env/immunology ; Genetic Vectors/administration & dosage ; Genetic Vectors/immunology ; Immunity, Cellular ; Immunity, Humoral ; Macaca mulatta ; Simian Acquired Immunodeficiency Syndrome/blood ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Immunodeficiency Virus/genetics ; Vaccination

المؤلفون: Penno C; School of Biochemistry, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland.; Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland., Kumari R; School of Biochemistry, University College Cork, Cork, Ireland., Baranov PV; School of Biochemistry, University College Cork, Cork, Ireland., van Sinderen D; School of Microbiology, University College Cork, Cork, Ireland.; Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland., Atkins JF; School of Biochemistry, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland.; Department of Human Genetics, University of Utah, Salt Lake City, UT 84112-5330, USA.

المصدر: Nucleic acids research [Nucleic Acids Res] 2017 Sep 29; Vol. 45 (17), pp. 10156-10167.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Frameshifting, Ribosomal* , Genes, gag* , Genes, pol* , INDEL Mutation*, Fusion Proteins, gag-pol/*metabolism , HIV Reverse Transcriptase/*metabolism , HIV-1/*genetics, Amino Acid Sequence ; Base Sequence ; Conserved Sequence ; DNA, Complementary/genetics ; Drug Resistance, Viral ; Fusion Proteins, gag-pol/genetics ; HIV Protease Inhibitors/pharmacology ; HIV Reverse Transcriptase/genetics ; Nucleic Acid Conformation ; Sequence Analysis, DNA ; Substrate Specificity

المؤلفون: Koivisto JM; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark., Poulsen NR; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark., Larsen BS; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark., Weibull MGM; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark., Stein A; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark., Doro F; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark., Winther JR; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark., Lindorff-Larsen K; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark., Willemoës M; From the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200N, Denmark.

المصدر: The Biochemical journal [Biochem J] 2022 Feb 17; Vol. 479 (4), pp. 479-501.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents/*pharmacokinetics , Drug Resistance, Viral/*genetics , HIV Protease/*genetics, Amino Acid Substitution ; AraC Transcription Factor/genetics ; Arabinose/metabolism ; Chymosin/metabolism ; Escherichia coli ; Escherichia coli Proteins/genetics ; Fusion Proteins, gag-pol/metabolism ; Gene Products, gag/metabolism ; Genes, araC ; HIV Protease/chemistry ; HIV Protease/isolation & purification ; HIV Protease/metabolism ; Models, Molecular ; Mutation, Missense ; Point Mutation ; Protein Conformation ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Saquinavir/antagonists & inhibitors ; Saquinavir/pharmacology ; Selection, Genetic ; Sequence Alignment ; Sequence Homology, Amino Acid ; Structure-Activity Relationship ; Substrate Specificity

المؤلفون: Yu FH; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Huang KJ; Division of Clinical Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan., Wang CT; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Division of Clinical Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.

المصدر: PloS one [PLoS One] 2022 Jan 27; Vol. 17 (1), pp. e0262477. Date of Electronic Publication: 2022 Jan 27 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acid Substitution/*genetics , HIV-1/*genetics , HIV-1/*pathogenicity, Amino Acid Sequence ; Cell Line ; Cell Line, Tumor ; Fusion Proteins, gag-pol/genetics ; HEK293 Cells ; HIV Protease/genetics ; HIV Seropositivity/genetics ; HeLa Cells ; Humans ; Mutation/genetics ; Virion/genetics ; Virus Replication/genetics